{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T08:38:11Z","timestamp":1785400691933,"version":"3.56.0"},"reference-count":44,"publisher":"Optica Publishing Group","issue":"8","license":[{"start":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T00:00:00Z","timestamp":1658793600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1364\/OA_License_v2#VOR-OA"},{"start":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T00:00:00Z","timestamp":1658793600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/opg.optica.org\/policies\/opg-tdm-policy.json"}],"content-domain":{"domain":["opg.optica.org"],"crossmark-restriction":false},"short-container-title":["Biomed. Opt. Express"],"published-print":{"date-parts":[[2022,8,1]]},"abstract":"<jats:p>\n                    We assessed the ability of the optical attenuation coefficient (AC) to detect early-stage glaucoma with two AC estimation algorithms: retinal layer intensity ratio (LIR) and depth-resolved confocal (DRC). We also introduced new depth-dependent AC parameters for retinal nerve fiber layer assessment. Optical coherence tomography B-scans were collected from 44 eyes of age-similar participants with eye health ranging from healthy to severe glaucoma, including glaucoma suspect patients. Mean AC values estimated from the DRC method are comparable to ratio-extracted values (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&gt;\u20090.5 for all study groups), and the depth-dependent AC\n                    <jats:sub>DRC<\/jats:sub>\n                    parameters enhance the utility of the AC for detection of early-stage glaucoma.\n                  <\/jats:p>","DOI":"10.1364\/boe.461348","type":"journal-article","created":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T12:30:09Z","timestamp":1658147409000},"page":"4326","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Depth-resolved extraction of optical attenuation for glaucoma assessment in clinical settings: a pilot study"],"prefix":"10.1364","volume":"13","author":[{"given":"Shuang","family":"Chang","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02vm5rt34","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Murff","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02vm5rt34","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodore","family":"Leng","sequence":"additional","affiliation":[{"name":"Byers Eye Institute at Stanford"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvia L.","family":"Groth","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey K.","family":"Bowden","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02vm5rt34","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2022,7,26]]},"reference":[{"key":"boe-13-8-4326-R1","first-page":"e144","volume":"9","author":"Adelson","year":"2020","journal-title":"Lancet Glob. 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