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Opt. Express"],"published-print":{"date-parts":[[2023,11,1]]},"abstract":"<jats:p>\n                    Autoantibodies against New York esophageal squamous cell cancer 1 (NY-ESO-1) play a crucial role in the diagnosis of esophageal cancer. In this work, a surface plasmonic tilted fiber Bragg grating (TFBG) biosensor is proposed for the detection of NY-ESO-1 antibody, as well as the investigation of the hook effect (which refers to the false negative result in some immunoassays when the concentration of antibodies in the sample is very high) during biomolecular binding between NY-ESO-1 antigen and antibody. The biosensor is made by an 18\u00b0 TFBG coated with a 50-nm-thick gold film over the fiber surface together with NY-ESO-1 antigens attached to the metallic surface serving as bio-receptors. This biosensor can provide a limit of detection at a concentration of 2\u2009\u00d7\u200910\n                    <jats:sup>\u22127<\/jats:sup>\n                    \u00b5g\/ml with a good linearity in the range from 2\u2009\u00d7\u200910\n                    <jats:sup>\u22127<\/jats:sup>\n                    to 2\u2009\u00d7\u200910\n                    <jats:sup>\u22125<\/jats:sup>\n                    \u00b5g\/ml. For a concentration higher than 2\u2009\u00d7\u200910\n                    <jats:sup>\u22123<\/jats:sup>\n                    \u00b5g\/ml, the performance of the sensor probe is reduced owing to the hook effect. Furthermore, experimental results have also demonstrated the repeatability of the proposed biosensor. This proposed biosensor features label-free, compactness, and fast response, which could be potentially applied in the diagnosis of esophageal cancer.\n                  <\/jats:p>","DOI":"10.1364\/boe.504401","type":"journal-article","created":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T09:00:05Z","timestamp":1697101205000},"page":"5921","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["NY-ESO-1 antigen-antibody interaction process based on an TFBG plasmonic sensor"],"prefix":"10.1364","volume":"14","author":[{"given":"Hang","family":"Qu","sequence":"first","affiliation":[{"name":"Shantou University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linyao","family":"Tan","sequence":"additional","affiliation":[{"name":"Shantou University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang-Cai","family":"Wu","sequence":"additional","affiliation":[{"name":"Cancer Hospital of Shantou University Medical College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiyuan","family":"Huang","sequence":"additional","affiliation":[{"name":"Shantou University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaiwei","family":"Li","sequence":"additional","affiliation":[{"name":"Jilin University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyong","family":"Chen","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01m8p7q42","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Wei","family":"Xu","sequence":"additional","affiliation":[{"name":"Cancer Hospital of Shantou University Medical College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0239-6144","authenticated-orcid":true,"given":"Xuehao","family":"Hu","sequence":"additional","affiliation":[{"name":"University of Mons"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2023,10,23]]},"reference":[{"key":"boe-14-11-5921-R1","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1016\/S0929-6646(10)60072-1","volume":"109","author":"Chung","year":"2010","journal-title":"J Formos Med Assoc."},{"key":"boe-14-11-5921-R2","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.6004\/jnccn.2019.7337","volume":"17","author":"Kelly","year":"2019","journal-title":"J Natl Compr Canc Netw."},{"key":"boe-14-11-5921-R3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/annonc\/5.suppl_3.S1","volume":"5","author":"Siewert","year":"2014","journal-title":"Ann Oncol."},{"key":"boe-14-11-5921-R4","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1038\/ajg.2013.384","volume":"109","author":"Xu","year":"2014","journal-title":"Am J Gastroenterol."},{"key":"boe-14-11-5921-R6","doi-asserted-by":"publisher","first-page":"e582","DOI":"10.1016\/j.clon.2023.06.014","volume":"35","author":"Sun","year":"2023","journal-title":"Clinical Oncology."},{"key":"boe-14-11-5921-R7","doi-asserted-by":"publisher","first-page":"103674","DOI":"10.1016\/j.ebiom.2021.103674","volume":"73","author":"Wang","year":"2021","journal-title":"EBioMedicine."},{"key":"boe-14-11-5921-R8","doi-asserted-by":"publisher","first-page":"3937","DOI":"10.3892\/ol.2019.10044","volume":"17","author":"Kakimoto","year":"2019","journal-title":"Oncology letters."},{"key":"boe-14-11-5921-R9","doi-asserted-by":"publisher","first-page":"104138","DOI":"10.1016\/j.bioorg.2020.104138","volume":"103","author":"Shi","year":"2020","journal-title":"Bioorg Chem."},{"key":"boe-14-11-5921-R10","doi-asserted-by":"publisher","first-page":"6551","DOI":"10.1158\/1078-0432.CCR-04-0819","volume":"10","author":"Fujita","year":"2004","journal-title":"Clinical cancer research : an official journal of the American Association for Cancer Research."},{"key":"boe-14-11-5921-R11","first-page":"1","volume":"95","author":"Gnjatic","year":"2006"},{"key":"boe-14-11-5921-R12","first-page":"67","author":"HosseiniHosseini","year":"2018"},{"key":"boe-14-11-5921-R13","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1109\/LPT.2017.2682183","volume":"29","author":"Chen","year":"2017","journal-title":"IEEE Photonics Technology Letters."},{"key":"boe-14-11-5921-R14","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.optlastec.2015.10.007","volume":"78","author":"Guo","year":"2016","journal-title":"Optics & Laser Technology."},{"key":"boe-14-11-5921-R15","doi-asserted-by":"publisher","first-page":"106615","DOI":"10.1016\/j.optlastec.2020.106615","volume":"134","author":"Wen","year":"2021","journal-title":"Optics & Laser Technology."},{"key":"boe-14-11-5921-R16","doi-asserted-by":"publisher","first-page":"16505","DOI":"10.1364\/OE.17.016505","volume":"17","author":"Piliarik","year":"2009","journal-title":"Opt. 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