{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:30:36Z","timestamp":1785429036642,"version":"3.56.0"},"reference-count":37,"publisher":"Optica Publishing Group","issue":"4","license":[{"start":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T00:00:00Z","timestamp":1710720000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1364\/OA_License_v2#VOR-OA"},{"start":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T00:00:00Z","timestamp":1710720000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/opg.optica.org\/policies\/opg-tdm-policy.json"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21EB028409"],"award-info":[{"award-number":["R21EB028409"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["opg.optica.org"],"crossmark-restriction":false},"short-container-title":["Biomed. Opt. Express"],"published-print":{"date-parts":[[2024,4,1]]},"abstract":"<jats:p>\n                    The mammalian oviduct (or fallopian tube) is a tubular organ hosting reproductive events leading to pregnancy. Dynamic 3D imaging of the mouse oviduct with optical coherence tomography (OCT) has recently emerged as a promising approach to study the hidden processes vital to elucidate the role of oviduct in mammalian reproduction and reproductive disorders. In particular, with an intravital window,\n                    <jats:italic>in vivo<\/jats:italic>\n                    OCT imaging is a powerful solution to studying how the oviduct transports preimplantation embryos towards the uterus for pregnancy, a long-standing question that is critical for uncovering the functional cause of tubal ectopic pregnancy. However, simultaneously tracking embryo movement and acquiring large-field-of-view images of oviduct activity in 3D has been challenging due to the generally limited volumetric imaging rate of OCT. A lack of OCT-based 3D velocimetry method for large, sparse particles acts as a technical hurdle for analyzing the mechanistic process of the embryo transport. Here, we report a new particle streak velocimetry method to address this hurdle. The method relies on the 3D streak of a moving particle formed during the acquisition of a single OCT volume, where double B-scans are acquired at each B-scan location to resolve ambiguity in assessing the movement of particle. We validated this method with the gold-standard, direct volumetric particle tracking in a flow phantom, and we demonstrated its\n                    <jats:italic>in vivo<\/jats:italic>\n                    applications for simultaneous velocimetry of embryos and imaging of oviduct. This work sets the stage for quantitative understanding of the oviduct transport function\n                    <jats:italic>in vivo<\/jats:italic>\n                    , and the method fills in a gap in OCT-based velocimetry, providing the potential to enable new applications in 3D flow imaging.\n                  <\/jats:p>","DOI":"10.1364\/boe.519595","type":"journal-article","created":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T16:00:10Z","timestamp":1709913610000},"page":"2466","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Three-dimensional particle streak velocimetry based on optical coherence tomography for assessing preimplantation embryo movement in mouse oviduct in vivo"],"prefix":"10.1364","volume":"15","author":[{"given":"Tianqi","family":"Fang","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02z43xh36","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Han","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02z43xh36","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyu","family":"Sun","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02z43xh36","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleese","family":"Mukhamedjanova","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02z43xh36","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9447-719X","authenticated-orcid":true,"given":"Shang","family":"Wang","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02z43xh36","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2024,3,18]]},"reference":[{"key":"boe-15-4-2466-R1","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1095\/biolreprod.115.135418","volume":"94","author":"Ishikawa","year":"2016","journal-title":"Biol. 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