{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:55:40Z","timestamp":1785426940162,"version":"3.56.0"},"reference-count":41,"publisher":"Optica Publishing Group","issue":"7","license":[{"start":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T00:00:00Z","timestamp":1750723200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T00:00:00Z","timestamp":1750723200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/opg.optica.org\/policies\/opg-tdm-policy.json"}],"funder":[{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","award":["610110"],"award-info":[{"award-number":["610110"]}],"id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR-15-RHUS-0001"],"award-info":[{"award-number":["ANR-15-RHUS-0001"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013388","name":"Office National d'\u00e9tudes et de Recherches A\u00e9rospatiales","doi-asserted-by":"publisher","award":["PRF TELEMAC"],"award-info":[{"award-number":["PRF TELEMAC"]}],"id":[{"id":"10.13039\/501100013388","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013388","name":"Office National d'\u00e9tudes et de Recherches A\u00e9rospatiales","doi-asserted-by":"publisher","award":["ONERA chair \"Seeing through fog\""],"award-info":[{"award-number":["ONERA chair \"Seeing through fog\""]}],"id":[{"id":"10.13039\/501100013388","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["opg.optica.org"],"crossmark-restriction":false},"short-container-title":["Biomed. Opt. Express"],"published-print":{"date-parts":[[2025,7,1]]},"abstract":"<jats:p>\n                    Structured illumination microscopy (SIM) is one of the most versatile super-resolution techniques. Yet, its application to high-resolution live imaging has been mainly limited to fluorescent and stationary specimens. Here, we present advancements in SIM to jointly tackle all the challenges of imaging living samples,\n                    <jats:italic>i.e.<\/jats:italic>\n                    , obtaining super-resolution over an undistorted wide-field while dealing with sample motion, multiple scattering, sample-induced optical aberrations, and low signal-to-noise ratio. By using adaptive optics to compensate for optical aberrations and a reconstruction algorithm tailored for moving and thick tissue, we successfully apply SIM to\n                    <jats:italic>in vivo<\/jats:italic>\n                    retinal imaging and demonstrate structured illumination ophthalmoscopy with optical sectioning and resolution improvement for\n                    <jats:italic>in vivo<\/jats:italic>\n                    imaging of the human retina.\n                  <\/jats:p>","DOI":"10.1364\/boe.559670","type":"journal-article","created":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T12:14:13Z","timestamp":1750767253000},"page":"2923","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["<i>In vivo<\/i>\n                    structured illumination ophthalmoscopy demonstration on the human retina using adaptive optics"],"prefix":"10.1364","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9749-6510","authenticated-orcid":true,"given":"Yann","family":"Lai-Tim","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/005y2ap84","id-type":"ROR","asserted-by":"publisher"}]},{"name":"Quinze-Vingts National Ophthalmology Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8364-4957","authenticated-orcid":true,"given":"Laurent M.","family":"Mugnier","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/005y2ap84","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5560-5443","authenticated-orcid":true,"given":"L\u00e9a","family":"Krafft","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/005y2ap84","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Chen","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Saclay and Quantel Medical"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyril","family":"Petit","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/005y2ap84","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7685-3999","authenticated-orcid":true,"given":"Pedro","family":"Mec\u00ea","sequence":"additional","affiliation":[{"name":"PSL University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Grieve","sequence":"additional","affiliation":[{"name":"Quinze-Vingts National Ophthalmology Hospital"},{"name":"Sorbonne Universit\u00e9"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Paques","sequence":"additional","affiliation":[{"name":"Quinze-Vingts National Ophthalmology Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6209-9443","authenticated-orcid":true,"given":"Serge","family":"Meimon","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/005y2ap84","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2025,6,24]]},"reference":[{"key":"boe-16-7-2923-R1","doi-asserted-by":"publisher","first-page":"2884","DOI":"10.1364\/JOSAA.14.002884","volume":"14","author":"Liang","year":"1997","journal-title":"J. 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Further distribution of this work must maintain attribution to the author(s) and the published article\u2019s title, journal citation, and DOI.","name":"copyright","label":"Copyright"}]}}