{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T03:25:10Z","timestamp":1785554710257,"version":"3.56.0"},"reference-count":31,"publisher":"Optica Publishing Group","issue":"8","license":[{"start":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T00:00:00Z","timestamp":1775433600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1364\/OA_License_v2#VOR"},{"start":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T00:00:00Z","timestamp":1775433600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/opg.optica.org\/policies\/opg-tdm-policy.json"}],"funder":[{"name":"Instruments Research & Development Establishment","award":["DIR\/ECS\/IRDE\/Proc(BCR)\/24-25\/003(CARS)"],"award-info":[{"award-number":["DIR\/ECS\/IRDE\/Proc(BCR)\/24-25\/003(CARS)"]}],"id":[{"id":"https:\/\/ror.org\/03jy6ar87","id-type":"ROR","asserted-by":"publisher"}]},{"name":"Indian Institute of Technology BHU","award":["IIT(BHU)\/RD\/2025-26\/CPCG-01\/608"],"award-info":[{"award-number":["IIT(BHU)\/RD\/2025-26\/CPCG-01\/608"]}],"id":[{"id":"https:\/\/ror.org\/01kh5gc44","id-type":"ROR","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002742","name":"Banaras Hindu University","doi-asserted-by":"crossref","award":["R\/Dev\/IoE\/ Incentive\/2021-22\/3244990"],"award-info":[{"award-number":["R\/Dev\/IoE\/ Incentive\/2021-22\/3244990"]}],"id":[{"id":"10.13039\/501100002742","id-type":"DOI","asserted-by":"crossref"},{"id":"https:\/\/ror.org\/04cdn2797","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":["opg.optica.org"],"crossmark-restriction":false},"short-container-title":["J. Opt. Soc. Am. A"],"published-print":{"date-parts":[[2026,8,1]]},"abstract":"<jats:p>The polarization of light is a fundamental property, and its measurement is desired for extracting the optical response of the interacting matter. The Jones matrix description directly assesses a sample\u2019s response to the light\u2013matter interactions. The Jones matrix approach uses a coherent basis and is suitable for expressing the interaction of coherent light with non-depolarizing samples, such as biological cells and thin samples. Usually, polarization measurement requires multiple measurements, which is unsuitable for dynamic samples. Here, we present a polarization digital holographic microscope to image the Jones matrix elements of biological cells from a single measurement. Using angular multiplexing, the proposed system employs a modified Mach\u2013Zehnder interferometer with two Sagnac interferometer geometries to image the complete Jones matrix elements from a single hologram. With this approach, we retrieve the complete Jones matrix for each pixel and perform a Jones matrix decomposition to extract key polarization parameters, including inhomogeneity, diattenuation, and retardance of the cervical cancer HeLa cells. This comprehensive set of quantitative parameters characterizes cellular anisotropy and offers a meaningful interpretation of light\u2013matter interaction in complex biological media.<\/jats:p>","DOI":"10.1364\/josaa.589616","type":"journal-article","created":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T12:00:10Z","timestamp":1773835210000},"page":"D10","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Decomposing the images of the Jones matrix microscope for quantitative analysis"],"prefix":"10.1364","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8644-2576","authenticated-orcid":true,"given":"Mohit","family":"Rathor","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01kh5gc44","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6690-3343","authenticated-orcid":true,"given":"Shivam Kumar","family":"Chaubey","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01kh5gc44","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akash","family":"Debnath","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01kh5gc44","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rupen","family":"Tamang","sequence":"additional","affiliation":[{"name":"Banaras Hindu University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biplob","family":"Koch","sequence":"additional","affiliation":[{"name":"Banaras Hindu University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3117-2695","authenticated-orcid":true,"given":"Rakesh Kumar","family":"Singh","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01kh5gc44","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2026,4,6]]},"reference":[{"key":"josaa-43-8-D10-R1","article-title":"Biomedical optical imaging technologies","volume-title":"Biological and Medical Physics, Biomedical Engineering","author":"Drexler","year":"2008"},{"key":"josaa-43-8-D10-R2","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1038\/nmeth817","type":"journal-article","volume":"2","author":"Lichtman","year":"2005","journal-title":"Nat. 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All rights, including for text and data mining (TDM), Artificial Intelligence (AI) training, and similar technologies, are reserved.","name":"copyright","label":"Copyright"}]}}