{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:16:51Z","timestamp":1785428211990,"version":"3.56.0"},"reference-count":23,"publisher":"Optica Publishing Group","issue":"18","license":[{"start":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T00:00:00Z","timestamp":1692662400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1364\/OA_License_v2#VOR-OA"},{"start":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T00:00:00Z","timestamp":1692662400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/opg.optica.org\/policies\/opg-tdm-policy.json"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["CZ55\/32-2"],"award-info":[{"award-number":["CZ55\/32-2"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["WA1657\/6-2"],"award-info":[{"award-number":["WA1657\/6-2"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","award":["201706500012"],"award-info":[{"award-number":["201706500012"]}],"id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["opg.optica.org"],"crossmark-restriction":false},"short-container-title":["Opt. Express"],"published-print":{"date-parts":[[2023,8,28]]},"abstract":"<jats:p>\n                    Various techniques in microscopy are based on point-wise acquisition, which provides advantages in acquiring sectioned images, for example in confocal or two-photon microscopy. The advantages come along with the need to perform three-dimensional scanning, which is often realized by mechanical movement achieved by stage-scanning or piezo-based scanning in the axial direction. Lateral scanning often employs galvo-mirrors, leading to a reflective setup and hence to a folded beam path. In this paper, we introduce a fully refractive microscope capable of three-dimensional scanning, which employs the combination of an adaptive lens, an adaptive prism, and a tailored telecentric f-theta objective. Our results show that this microscope is capable to perform flexible three-dimensional scanning, with low scan-induced aberrations, at a uniform resolution over a large tuning range of\n                    <jats:italic>X<\/jats:italic>\n                    =\n                    <jats:italic>Y<\/jats:italic>\n                    =6300\u00a0\n                    <jats:italic>\u03bc<\/jats:italic>\n                    m and\n                    <jats:italic>Z<\/jats:italic>\n                    =480\u00a0\n                    <jats:italic>\u03bc<\/jats:italic>\n                    m with only transmissive components. We demonstrate the capabilities at the example of volumetric measurements on the transgenic fluorescence of the thyroid of a zebrafish embryo and mixed pollen grains. This is the first step towards flexible aberration-free volumetric smart microscopy of three-dimensional samples like embryos and organoids, which could be exploited for the demands in both lateral and axial dimensions in biomedical samples without compromising image quality.\n                  <\/jats:p>","DOI":"10.1364\/oe.496150","type":"journal-article","created":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T14:53:40Z","timestamp":1692716020000},"page":"29703","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Fully refractive telecentric f-theta microscope based on adaptive elements for 3D raster scanning of biological tissues"],"prefix":"10.1364","volume":"31","author":[{"given":"Wenjie","family":"Wang","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/042aqky30","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4562-0759","authenticated-orcid":true,"given":"Katharina","family":"Schmidt","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/042aqky30","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1324-1615","authenticated-orcid":true,"given":"Matthias C.","family":"Wapler","sequence":"additional","affiliation":[{"name":"University of Freiburg"},{"name":"Otto von Guericke University Magdeburg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0532-1519","authenticated-orcid":true,"given":"Ulrike","family":"Wallrabe","sequence":"additional","affiliation":[{"name":"University of Freiburg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen W.","family":"Czarske","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/042aqky30","id-type":"ROR","asserted-by":"publisher"}]},{"name":"TU Dresden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nektarios","family":"Koukourakis","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/042aqky30","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2023,8,22]]},"reference":[{"key":"oe-31-18-29703-R1","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1126\/science.1082160","volume":"300","author":"Stephens","year":"2003","journal-title":"Science"},{"key":"oe-31-18-29703-R2","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1126\/science.2321027","volume":"248","author":"Denk","year":"1990","journal-title":"Science"},{"key":"oe-31-18-29703-R3","doi-asserted-by":"publisher","first-page":"6025","DOI":"10.1364\/OE.22.006025","volume":"22","author":"Koukourakis","year":"2014","journal-title":"Opt. 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