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Lett."],"published-print":{"date-parts":[[2020,11,1]]},"abstract":"<jats:p>We present a scheme for correction of <jats:inline-formula>\n      <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" display=\"inline\">\n\t<mml:mi>x<\/mml:mi>\n      <\/mml:math>\n    <\/jats:inline-formula>-<jats:inline-formula>\n      <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" display=\"inline\">\n\t<mml:mi>y<\/mml:mi>\n      <\/mml:math>\n    <\/jats:inline-formula>-separable aberrations in optical\n\t\t\t\t\tcoherence tomography (OCT) designed to work with phase unstable\n\t\t\t\t\tsystems with no hardware modifications. Our approach, termed SHARP, is\n\t\t\t\t\tbased on computational adaptive optics and numerical phase correction\n\t\t\t\t\tand follows from the fact that local phase stability is sufficient for\n\t\t\t\t\tthe deconvolution of optical aberrations. We demonstrate its\n\t\t\t\t\tapplicability in a raster-scan polygon-laser OCT system with strong\n\t\t\t\t\tphase-jitter noise, achieving successful refocusing at depths up to 4\n\t\t\t\t\ttimes the Rayleigh range. We also present <jats:italic toggle=\"yes\">in\n\t\t\t\t\tvivo<\/jats:italic> endoscopic and <jats:italic toggle=\"yes\">ex vivo<\/jats:italic>\n\t\t\t\t\tanterior segment OCT data, showing significant enhancement of image\n\t\t\t\t\tquality, particularly when combining SHARP results with a\n\t\t\t\t\tresolution-preserving despeckling technique like TNode.<\/jats:p>","DOI":"10.1364\/ol.401283","type":"journal-article","created":{"date-parts":[[2020,9,8]],"date-time":"2020-09-08T14:30:28Z","timestamp":1599575428000},"page":"5982","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Computational adaptive optics in phase-unstable optical coherence tomography"],"prefix":"10.1364","volume":"45","author":[{"given":"Sebasti\u00e1n","family":"Ruiz-Lopera","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9","family":"Restrepo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Cuartas-V\u00e9lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett E.","family":"Bouma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9201-2196","authenticated-orcid":true,"given":"N\u00e9stor","family":"Uribe-Patarroyo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2020,10,27]]},"reference":[{"key":"ol-45-21-5982-R1","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1586\/17469899.2.6.1019","volume":"2","author":"Pircher","year":"2007","journal-title":"Expert Rev. 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