{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:48:29Z","timestamp":1790812109392,"version":"4.1.0"},"reference-count":21,"publisher":"Optica Publishing Group","issue":"12","license":[{"start":{"date-parts":[[2022,6,7]],"date-time":"2022-06-07T00:00:00Z","timestamp":1654560000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1364\/OA_License_v2#VOR"},{"start":{"date-parts":[[2022,6,7]],"date-time":"2022-06-07T00:00:00Z","timestamp":1654560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/opg.optica.org\/policies\/opg-tdm-policy.json"}],"funder":[{"name":"Shandong Key Research and Development\n\t\t\t\t\t\tProgram","award":["2021CXGC010212"],"award-info":[{"award-number":["2021CXGC010212"]}]},{"DOI":"10.13039\/501100010877","name":"Science, Technology and Innovation\n\t\t\t\t\t\tCommission of Shenzhen Municipality","doi-asserted-by":"publisher","award":["KQTD20200820113012029"],"award-info":[{"award-number":["KQTD20200820113012029"]}],"id":[{"id":"10.13039\/501100010877","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Guangdong Natural Science Foundation\n\t\t\t\t\t\tJoint Fund","award":["2020A1515110380"],"award-info":[{"award-number":["2020A1515110380"]}]},{"name":"Guangdong Provincial Key Laboratory of\n\t\t\t\t\t\tAdvanced Biomaterials","award":["2022B1212010003"],"award-info":[{"award-number":["2022B1212010003"]}]},{"name":"Startup grant from Southern University of\n\t\t\t\t\t\tScience and Technology"}],"content-domain":{"domain":["opg.optica.org"],"crossmark-restriction":false},"short-container-title":["Opt. Lett."],"published-print":{"date-parts":[[2022,6,15]]},"abstract":"<jats:p>Point spread function (PSF) engineering is an important technique to\n\t\t\t\t\tencode the properties (e.g., 3D positions, color, and orientation) of\n\t\t\t\t\ta single molecule in the shape of the PSF, often with the help of a\n\t\t\t\t\tprogrammable phase modulator. A deformable mirror (DM) is currently\n\t\t\t\t\tthe most widely used phase modulator for fluorescence detection as it\n\t\t\t\t\tshows negligible photon loss. However, it relies on careful\n\t\t\t\t\tcalibration for precise wavefront control. Therefore, design of an\n\t\t\t\t\toptimal PSF not only relies on the theoretical calculation of the\n\t\t\t\t\tmaximum information content, but also the physical behavior of the\n\t\t\t\t\tphase modulator, which is often ignored during the optimization\n\t\t\t\t\tprocess. Here, we develop a framework for PSF engineering which could\n\t\t\t\t\tgenerate a device specific optimal PSF for 3D super-resolution imaging\n\t\t\t\t\tusing a DM. We use our method to generate two types of PSFs with\n\t\t\t\t\tdepths of field comparable to the widely used astigmatism and tetrapod\n\t\t\t\t\tPSFs, respectively. We demonstrate the superior performance of the DM\n\t\t\t\t\tspecific optimal PSF over the conventional astigmatism and tetrapod\n\t\t\t\t\tPSF both theoretically and experimentally.<\/jats:p>","DOI":"10.1364\/ol.460949","type":"journal-article","created":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T07:30:44Z","timestamp":1653377444000},"page":"3031","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Deformable mirror based optimal PSF engineering for 3D super-resolution imaging"],"prefix":"10.1364","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0132-5707","authenticated-orcid":true,"given":"Shuang","family":"Fu","sequence":"first","affiliation":[{"name":"Southern University of Science and Technology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengfan","family":"Li","sequence":"additional","affiliation":[{"name":"Southern University of Science and Technology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lulu","family":"Zhou","sequence":"additional","affiliation":[{"name":"Southern University of Science and Technology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingchuan","family":"He","sequence":"additional","affiliation":[{"name":"Southern University of Science and Technology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Liu","sequence":"additional","affiliation":[{"name":"Zhejiang University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3931-6884","authenticated-orcid":true,"given":"Xiang","family":"Hao","sequence":"additional","affiliation":[{"name":"Zhejiang University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4109-3824","authenticated-orcid":true,"given":"Yiming","family":"Li","sequence":"additional","affiliation":[{"name":"Southern University of Science and Technology"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2022,6,7]]},"reference":[{"key":"ol-47-12-3031-R1","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1146\/annurev-biophys-102521-112912","volume":"51","author":"Liu","year":"2022","journal-title":"Annu. Rev. Biophys."},{"key":"ol-47-12-3031-R2","doi-asserted-by":"publisher","first-page":"12483","DOI":"10.1021\/acsnano.1c04708","volume":"15","author":"Xiang","year":"2021","journal-title":"ACS Nano"},{"key":"ol-47-12-3031-R3","doi-asserted-by":"publisher","first-page":"7244","DOI":"10.1021\/acs.chemrev.6b00629","volume":"117","author":"von Diezmann","year":"2017","journal-title":"Chem. Rev."},{"key":"ol-47-12-3031-R4","doi-asserted-by":"publisher","first-page":"4194","DOI":"10.1021\/acs.nanolett.5b01396","volume":"15","author":"Shechtman","year":"2015","journal-title":"Nano Lett."},{"key":"ol-47-12-3031-R5","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1126\/science.1153529","volume":"319","author":"Huang","year":"2008","journal-title":"Science"},{"key":"ol-47-12-3031-R6","doi-asserted-by":"publisher","first-page":"3067","DOI":"10.1038\/s41467-021-23279-6","volume":"12","author":"Orange-Kedem","year":"2021","journal-title":"Nat. Commun."},{"key":"ol-47-12-3031-R7","doi-asserted-by":"publisher","first-page":"2995","DOI":"10.1073\/pnas.0900245106","volume":"106","author":"Pavani","year":"2009","journal-title":"Proc. Natl. Acad. Sci."},{"key":"ol-47-12-3031-R8","doi-asserted-by":"publisher","first-page":"133902","DOI":"10.1103\/PhysRevLett.113.133902","volume":"113","author":"Shechtman","year":"2014","journal-title":"Phys. Rev. Lett."},{"key":"ol-47-12-3031-R9","doi-asserted-by":"publisher","first-page":"2409","DOI":"10.1038\/s41467-018-04709-4","volume":"9","author":"Aristov","year":"2018","journal-title":"Nat. Commun."},{"key":"ol-47-12-3031-R10","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1038\/s41592-020-0853-5","volume":"17","author":"Nehme","year":"2020","journal-title":"Nat. Methods"},{"key":"ol-47-12-3031-R11","doi-asserted-by":"publisher","first-page":"2466","DOI":"10.1364\/OL.388695","volume":"45","author":"Zhou","year":"2020","journal-title":"Opt. Lett."},{"key":"ol-47-12-3031-R12","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1364\/OPTICA.2.000177","volume":"2","author":"Burke","year":"2015","journal-title":"Optica"},{"key":"ol-47-12-3031-R13","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1038\/s41592-018-0053-8","volume":"15","author":"Mlodzianoski","year":"2018","journal-title":"Nat. Methods"},{"key":"ol-47-12-3031-R14","doi-asserted-by":"publisher","first-page":"8397","DOI":"10.1364\/OE.26.008397","volume":"26","author":"Siemons","year":"2018","journal-title":"Opt. Express"},{"key":"ol-47-12-3031-R15","doi-asserted-by":"publisher","first-page":"3275","DOI":"10.1364\/BOE.451634","volume":"13","author":"Hung","year":"2022","journal-title":"Biomed. Opt. Express"},{"key":"ol-47-12-3031-R16","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1038\/nmeth.4661","volume":"15","author":"Li","year":"2018","journal-title":"Nat. Methods"},{"key":"ol-47-12-3031-R17","doi-asserted-by":"publisher","first-page":"1082","DOI":"10.1038\/s41592-021-01236-x","volume":"18","author":"Speiser","year":"2021","journal-title":"Nat. Methods"},{"key":"ol-47-12-3031-R19","doi-asserted-by":"publisher","first-page":"24461","DOI":"10.1364\/OE.18.024461","volume":"18","author":"Stallinga","year":"2010","journal-title":"Opt. Express"},{"key":"ol-47-12-3031-R20","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1038\/s41592-019-0574-9","volume":"16","author":"Thevathasan","year":"2019","journal-title":"Nat. Methods"},{"key":"ol-47-12-3031-R21","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1038\/nmeth.2448","volume":"10","author":"Nieuwenhuizen","year":"2013","journal-title":"Nat. Methods"},{"key":"ol-47-12-3031-R22","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1038\/nmeth.2566","volume":"10","author":"El Beheiry","year":"2013","journal-title":"Nat. Methods"}],"container-title":["Optics Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/opg.optica.org\/viewmedia.cfm?URI=ol-47-12-3031&seq=0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T15:28:45Z","timestamp":1722958125000},"score":1,"resource":{"primary":{"URL":"https:\/\/opg.optica.org\/abstract.cfm?URI=ol-47-12-3031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,7]]},"references-count":21,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022]]},"published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.1364\/ol.460949","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2022.05.09.491071","asserted-by":"object"}]},"ISSN":["0146-9592","1539-4794"],"issn-type":[{"value":"0146-9592","type":"print"},{"value":"1539-4794","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,7]]},"assertion":[{"value":"Optica Publishing Group","name":"publisher","label":"This article is maintained by"},{"value":"https:\/\/doi.org\/10.1364\/OL.460949","name":"articlelink","label":"Crossref DOI link to publisher maintained version"},{"value":"letter","name":"content_type","label":"Article type"},{"value":"Screened by Similarity Check","name":"cross_check","label":"Similarity check"},{"value":"Yes","order":0,"name":"peer_reviewed","label":"Peer reviewed","group":{"name":"peer_review","label":"Peer review"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review process","group":{"name":"peer_review","label":"Peer review"}},{"value":"14 April 2022","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"23 May 2022","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"7 June 2022","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2022 Optica Publishing\n\t\t\t\t\tGroup","name":"copyright","label":"Copyright"}]}}