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Lett."],"published-print":{"date-parts":[[2025,3,15]]},"abstract":"<jats:p>Optical coherence tomography (OCT) systems utilize 2D scanning methods to acquire reflectance-based volumetric images of samples, such as the human retina, with micrometer-scale depth resolution. A common method for performing this scanning at high speeds is to use a pair of sequential, single-axis galvanometer scanners. An undesired effect of using separated scanners is the variation in the beam position at the pupil plane, a phenomenon known as beam wander or pupil wobble. This can lead to loss of signal and vignetting artifacts in the resulting images. To overcome these limitations, we propose a method to deterministically analyze the pupil wobble in a given retinal OCT system and to correct for the displacement using pupil tracking OCT with a 2D scanning mirror placed anti-conjugate to the pupil plane. We demonstrate that we can model the pattern of pupil wobble present in any OCT system both theoretically and empirically and then use a pupil tracking system to correct for the displacement of the beam to acquire OCT images without the imposed artifacts.<\/jats:p>","DOI":"10.1364\/ol.547035","type":"journal-article","created":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T12:00:03Z","timestamp":1739361603000},"page":"1969","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pupil wobble in point-scanning retinal optical coherence tomography systems"],"prefix":"10.1364","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7881-8898","authenticated-orcid":true,"given":"Amit","family":"Narawane","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00py81415","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3756-2440","authenticated-orcid":true,"given":"Pablo","family":"Ortiz","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00py81415","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5051-0880","authenticated-orcid":true,"given":"Mark","family":"Draelos","sequence":"additional","affiliation":[{"name":"University of Michigan"},{"name":"University of Michigan Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1686-4191","authenticated-orcid":true,"given":"Ryan P.","family":"McNabb","sequence":"additional","affiliation":[{"name":"Duke University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony N.","family":"Kuo","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00py81415","id-type":"ROR","asserted-by":"publisher"}]},{"name":"Duke University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph A.","family":"Izatt","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00py81415","id-type":"ROR","asserted-by":"publisher"}]},{"name":"Duke University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2025,3,10]]},"reference":[{"key":"ol-50-6-1969-R1","doi-asserted-by":"publisher","first-page":"1178","DOI":"10.1126\/science.1957169","volume":"254","author":"Huang","year":"1991","journal-title":"Science"},{"key":"ol-50-6-1969-R2","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1001\/archopht.1995.01100030081025","volume":"113","author":"Hee","year":"1995","journal-title":"Arch. 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Draelos M. , \u201c Pupil-wobble ,\u201d\u00a0 GitHub \u00a0( 2024 ), https:\/\/github.com\/amit-narawane\/Pupil-Wobble ."}],"container-title":["Optics Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/opg.optica.org\/viewmedia.cfm?URI=ol-50-6-1969&seq=0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T13:07:26Z","timestamp":1741612046000},"score":1,"resource":{"primary":{"URL":"https:\/\/opg.optica.org\/abstract.cfm?URI=ol-50-6-1969"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,10]]},"references-count":11,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025]]},"published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.1364\/ol.547035","relation":{},"ISSN":["0146-9592","1539-4794"],"issn-type":[{"value":"0146-9592","type":"print"},{"value":"1539-4794","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,10]]},"assertion":[{"value":"Optica Publishing Group","name":"publisher","label":"This article is maintained by"},{"value":"https:\/\/doi.org\/10.1364\/OL.547035","name":"articlelink","label":"Crossref DOI link to publisher maintained version"},{"value":"letter","name":"content_type","label":"Article type"},{"value":"Screened by Similarity Check","name":"cross_check","label":"Similarity check"},{"value":"Yes","order":0,"name":"peer_reviewed","label":"Peer reviewed","group":{"name":"peer_review","label":"Peer review"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review process","group":{"name":"peer_review","label":"Peer review"}},{"value":"5 November 2024","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"12 February 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"10 March 2025","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2025 Optica Publishing Group. All rights, including for text and data mining (TDM), Artificial Intelligence (AI) training, and similar technologies, are reserved.","name":"copyright","label":"Copyright"}]}}