{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T12:41:51Z","timestamp":1785415311999,"version":"3.56.0"},"reference-count":10,"publisher":"Optica Publishing Group","issue":"12","license":[{"start":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T00:00:00Z","timestamp":1748822400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1364\/OA_License_v2#VOR"},{"start":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T00:00:00Z","timestamp":1748822400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/opg.optica.org\/policies\/opg-tdm-policy.json"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62027824"],"award-info":[{"award-number":["62027824"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62205010"],"award-info":[{"award-number":["62205010"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005089","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["L223018"],"award-info":[{"award-number":["L223018"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["YWF-22-L1265"],"award-info":[{"award-number":["YWF-22-L1265"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["opg.optica.org"],"crossmark-restriction":false},"short-container-title":["Opt. Lett."],"published-print":{"date-parts":[[2025,6,15]]},"abstract":"<jats:p>Accurate visualization of corneal microstructures with micrometer resolution is critical for diagnosing ocular diseases and guiding treatment strategies. Reflectance confocal microscopy (RCM) was developed for high-resolution three-dimensional (3D) imaging, but its reliance on mechanical scanning limits the 3D imaging speed and may introduce motion artifacts. Here, we demonstrated a time-stretch chromatic confocal microscopy (TSCCM), a single-shot volumetric imaging technique that eliminates mechanical axial scanning by encoding depth information into time-domain swept waveforms. A supercontinuum laser pulse is temporally stretched from picoseconds to 85\u2005ns using free-space angular-chirp-enhanced delay (FACED). FACED enables a low-loss dispersive system that replaces conventional single-mode fiber (SMF), reducing power loss by 1.4\u20131.8\u00d7 while achieving a dispersion of 0.55\u2005ns\/nm across 650\u2013850\u2005nm. Combined with a chromatic objective, TSCCM enables depth-resolved detection at an A-scan rate of up to 1\u2005MHz. Our system achieves 5 volumes per second with 1\u20132.2\u2005\u03bcm lateral resolution, 346\u2005\u03bcm penetration depth in phantoms, and 150\u2005\u03bcm in rodent corneas. By decoupling imaging speed from mechanical constraints, TSCCM offers a transformative platform for real-time, high-resolution ophthalmic diagnostics.<\/jats:p>","DOI":"10.1364\/ol.564590","type":"journal-article","created":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T06:59:49Z","timestamp":1747205989000},"page":"3828","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development and characterization of a temporal dispersive chromatic confocal microscopy for enhancing real-time three-dimensional cornea imaging"],"prefix":"10.1364","volume":"50","author":[{"given":"Zhexi","family":"Liu","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00wk2mp56","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuefang","family":"Yang","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00wk2mp56","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianghao","family":"Shen","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00wk2mp56","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xun","family":"Chen","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00wk2mp56","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1830-008X","authenticated-orcid":true,"given":"Shuhua","family":"Yue","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00wk2mp56","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5355-1613","authenticated-orcid":true,"given":"Pu","family":"Wang","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00wk2mp56","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2025,6,2]]},"reference":[{"key":"ol-50-12-3828-R1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s42399-019-00207-w","volume":"2","author":"\u00c1vila","year":"2020","journal-title":"SN Compr. 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All rights, including for text and data mining (TDM), Artificial Intelligence (AI) training, and similar technologies, are reserved.","name":"copyright","label":"Copyright"}]}}