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Lett."],"published-print":{"date-parts":[[2026,2,1]]},"abstract":"<jats:p>\n                    Optofluidic whispering gallery mode microbubble cavities offer several advantages, including high quality factors, small mode volumes, and real-time detection capabilities, making them well-suited for applications in high-precision sensing. The sensing mechanism of microcavity-based solution sensors typically relies on detecting mode shifts, broadening, or splitting induced by variations in the refractive index of the analyte. In this study, we introduce a novel, to the best of our knowledge, detection method that integrates cavity photothermal oscillation spectroscopy with a deep neural network. This hybrid technique enables high-precision detection of anhydrous ethanol concentrations in multi-component mixture solution while remaining insensitive to mode shifts. Experimental results demonstrate a predicted accuracy of 0.992 and a mean squared error of 5.29\u2009\u00d7\u200910\n                    <jats:sup>\u22124<\/jats:sup>\n                    within the 0\u20131% concentration range.\n                  <\/jats:p>","DOI":"10.1364\/ol.582789","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T20:00:09Z","timestamp":1768248009000},"page":"792","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cavity photothermal oscillation spectroscopy generation in an optofluidic microbubble resonator for multi-component mixture solution detection"],"prefix":"10.1364","volume":"51","author":[{"given":"Weida","family":"Chen","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/020azk594","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianhe","family":"Wu","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/020azk594","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya","family":"Hu","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/020azk594","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Li","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/020azk594","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Huang","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/020azk594","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2760-5224","authenticated-orcid":true,"given":"Hongliang","family":"Ren","sequence":"additional","affiliation":[{"name":"Zhejiang University of Technology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2484-7292","authenticated-orcid":true,"given":"Chang-Ling","family":"Zou","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Quantum Information, University of Science and Technology of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9137-0298","authenticated-orcid":true,"given":"Xiankai","family":"Sun","sequence":"additional","affiliation":[{"name":"The Chinese University of Hong Kong, Shatin, New Territories"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianzeng","family":"Zhang","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/020azk594","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7786-0437","authenticated-orcid":true,"given":"Qijing","family":"Lu","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/020azk594","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2026,1,30]]},"reference":[{"key":"ol-51-3-792-R1","doi-asserted-by":"publisher","first-page":"1444","DOI":"10.1021\/acs.analchem.7b05330","type":"journal-article","volume":"90","author":"Wrobel","year":"2018","journal-title":"Anal. 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All rights, including for text and data mining (TDM), Artificial Intelligence (AI) training, and similar technologies, are reserved.","name":"copyright","label":"Copyright"}]}}