{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T08:45:57Z","timestamp":1785401157466,"version":"3.56.0"},"reference-count":27,"publisher":"Optica Publishing Group","issue":"13","license":[{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1364\/OA_License_v2#VOR"},{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/opg.optica.org\/policies\/opg-tdm-policy.json"}],"funder":[{"name":"Central Project Management Agency","award":["10-038-T-0048"],"award-info":[{"award-number":["10-038-T-0048"]}]},{"name":"Central Project Management Agency","award":["10-038-T-0300"],"award-info":[{"award-number":["10-038-T-0300"]}]}],"content-domain":{"domain":["opg.optica.org"],"crossmark-restriction":false},"short-container-title":["Opt. Lett."],"published-print":{"date-parts":[[2026,7,1]]},"abstract":"<jats:p>Fourier-domain Full-Field Optical Coherence Microscopy (FD-FF-OCM)\n\t\t\t\t\tenables high-resolution, high-speed volumetric imaging but provides\n\t\t\t\t\tlimited intrinsic contrast. We present dynamic FD-FF-OCM, which\n\t\t\t\t\tenhances contrast by analyzing temporal fluctuations in the complex\n\t\t\t\t\tFD-FF-OCM signal. The system provides access to fluctuation\n\t\t\t\t\tfrequencies of 0.3\u201358\u2009Hz while acquiring wide-field volumetric data\n\t\t\t\t\tover a 200\u2009\u00b5m axial range in 3.3\u2009s, with dynamic cellular features\n\t\t\t\t\tclearly resolved down to 70\u2009\u00b5m and blurred structural contrast\n\t\t\t\t\tremaining visible at larger depths. Imaging of freshly excised mouse\n\t\t\t\t\tliver demonstrates substantially improved contrast over static\n\t\t\t\t\tFD-FF-OCM, enabling clearer visualization of hepatocytes, their\n\t\t\t\t\tnuclei, and sinusoids.<\/jats:p>","DOI":"10.1364\/ol.597379","type":"journal-article","created":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T12:00:09Z","timestamp":1780056009000},"page":"3581","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Dynamic Fourier-domain full-field optical coherence microscopy"],"prefix":"10.1364","volume":"51","author":[{"given":"Aust\u0117ja","family":"Tre\u010diokait\u0117","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erikas","family":"Tarvydas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3742-067X","authenticated-orcid":true,"given":"Egidijus","family":"Auksorius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2026,6,23]]},"reference":[{"key":"ol-51-13-3581-R1","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1038\/s41377-022-00740-9","type":"journal-article","volume":"11","author":"Sampson","year":"2022","journal-title":"Light: Sci.\n\t\t\t\t\tAppl."},{"key":"ol-51-13-3581-R2","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1038\/s43586-025-00406-x","type":"journal-article","volume":"5","author":"Singh","year":"2025","journal-title":"Nat. Rev. Methods\n\t\t\t\t\tPrimers"},{"key":"ol-51-13-3581-R3","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1038\/s42003-024-05973-5","type":"journal-article","volume":"7","author":"Ren","year":"2024","journal-title":"Commun.\n\t\t\t\t\tBiol."},{"key":"ol-51-13-3581-R4","doi-asserted-by":"publisher","first-page":"036601","DOI":"10.1088\/1361-6633\/ad2229","type":"journal-article","volume":"87","author":"Nolte","year":"2024","journal-title":"Rep. Prog. Phys."},{"key":"ol-51-13-3581-R5","doi-asserted-by":"publisher","first-page":"1511","DOI":"10.1364\/BOE.7.001511","type":"journal-article","volume":"7","author":"Apelian","year":"2016","journal-title":"Biomed. Opt.\n\t\t\t\t\tExpress"},{"key":"ol-51-13-3581-R6","doi-asserted-by":"publisher","first-page":"992","DOI":"10.1038\/s42003-023-05378-w","type":"journal-article","volume":"6","author":"Monfort","year":"2023","journal-title":"Commun.\n\t\t\t\t\tBiol."},{"key":"ol-51-13-3581-R7","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1038\/s42003-022-03479-6","type":"journal-article","volume":"5","author":"Groux","year":"2022","journal-title":"Commun.\n\t\t\t\t\tBiol."},{"key":"ol-51-13-3581-R8","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1038\/s41377-020-00375-8","type":"journal-article","volume":"9","author":"Scholler","year":"2020","journal-title":"Light: Sci.\n\t\t\t\t\tAppl."},{"key":"ol-51-13-3581-R9","doi-asserted-by":"publisher","first-page":"2768","DOI":"10.1364\/BOE.390782","type":"journal-article","volume":"11","author":"Leung","year":"2020","journal-title":"Biomed. Opt.\n\t\t\t\t\tExpress"},{"key":"ol-51-13-3581-R10","doi-asserted-by":"publisher","first-page":"4766","DOI":"10.1364\/OL.396134","type":"journal-article","volume":"45","author":"M\u00fcnter","year":"2020","journal-title":"Opt. Lett."},{"key":"ol-51-13-3581-R11","doi-asserted-by":"publisher","first-page":"6024","DOI":"10.1364\/BOE.425001","type":"journal-article","volume":"12","author":"M\u00fcnter","year":"2021","journal-title":"Biomed. Opt.\n\t\t\t\t\tExpress"},{"key":"ol-51-13-3581-R12","doi-asserted-by":"publisher","first-page":"32426","DOI":"10.1038\/s41598-025-15032-6","type":"journal-article","volume":"15","author":"Burhan","year":"2025","journal-title":"Sci. Rep."},{"key":"ol-51-13-3581-R13","doi-asserted-by":"publisher","first-page":"6761","DOI":"10.1364\/OE.20.006761","type":"journal-article","volume":"20","author":"Hillmann","year":"2012","journal-title":"Opt.\n\t\t\t\t\tExpress"},{"key":"ol-51-13-3581-R14","doi-asserted-by":"publisher","first-page":"35209","DOI":"10.1038\/srep35209","type":"journal-article","volume":"6","author":"Hillmann","year":"2016","journal-title":"Sci. Rep."},{"key":"ol-51-13-3581-R15","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1364\/OPTICA.6.000608","type":"journal-article","volume":"6","author":"Stremplewski","year":"2019","journal-title":"Optica"},{"key":"ol-51-13-3581-R16","doi-asserted-by":"publisher","first-page":"6390","DOI":"10.1364\/BOE.10.006390","type":"journal-article","volume":"10","author":"Auksorius","year":"2019","journal-title":"Biomed. Opt. Express"},{"key":"ol-51-13-3581-R17","doi-asserted-by":"publisher","first-page":"105513","DOI":"10.1016\/j.isci.2022.105513","type":"journal-article","volume":"25","author":"Auksorius","year":"2022","journal-title":"iScience"},{"key":"ol-51-13-3581-R18","doi-asserted-by":"publisher","first-page":"1695","DOI":"10.1364\/BOE.584783","type":"journal-article","volume":"17","author":"Tateno","year":"2026","journal-title":"Biomed. Opt.\n\t\t\t\t\tExpress"},{"key":"ol-51-13-3581-R19","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.bbe.2025.01.001","type":"journal-article","volume":"45","author":"Miku\u0142a-Zda\u0144kowska","year":"2025","journal-title":"Biocybern. Biomed.\n\t\t\t\t\tEng."},{"key":"ol-51-13-3581-R20","doi-asserted-by":"publisher","first-page":"2099","DOI":"10.1364\/OPTCON.564109","type":"journal-article","volume":"4","author":"Adomavi\u010dius","year":"2025","journal-title":"Opt.\n\t\t\t\t\tContinuum"},{"key":"ol-51-13-3581-R21","doi-asserted-by":"publisher","first-page":"33500","DOI":"10.1364\/OE.498654","type":"journal-article","volume":"31","author":"Puyo","year":"2023","journal-title":"Opt.\n\t\t\t\t\tExpress"},{"key":"ol-51-13-3581-R22","doi-asserted-by":"publisher","first-page":"1413","DOI":"10.1364\/OL.417178","type":"journal-article","volume":"46","author":"Auksorius","year":"2021","journal-title":"Opt. Lett."},{"key":"ol-51-13-3581-R23","doi-asserted-by":"publisher","first-page":"2849","DOI":"10.1364\/BOE.393801","type":"journal-article","volume":"11","author":"Auksorius","year":"2020","journal-title":"Biomed. Opt.\n\t\t\t\t\tExpress"},{"key":"ol-51-13-3581-R24","doi-asserted-by":"publisher","first-page":"3061","DOI":"10.1364\/BOE.563044","type":"journal-article","volume":"16","author":"Bellesini","year":"2025","journal-title":"Biomed. Opt.\n\t\t\t\t\tExpress"},{"key":"ol-51-13-3581-R25","doi-asserted-by":"publisher","first-page":"19412","DOI":"10.1364\/OE.21.019412","type":"journal-article","volume":"21","author":"Ju","year":"2013","journal-title":"Opt.\n\t\t\t\t\tExpress"},{"key":"ol-51-13-3581-R26","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1038\/s44303-026-00153-y","type":"journal-article","volume":"4","author":"Tarvydas","year":"2026","journal-title":"npj Imaging"},{"key":"ol-51-13-3581-R27","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1364\/BOE.581000","type":"journal-article","volume":"17","author":"Thakur","year":"2026","journal-title":"Biomed. Opt.\n\t\t\t\t\tExpress"}],"container-title":["Optics Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/opg.optica.org\/viewmedia.cfm?URI=ol-51-13-3581&seq=0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T14:19:08Z","timestamp":1782397148000},"score":1,"resource":{"primary":{"URL":"https:\/\/opg.optica.org\/abstract.cfm?URI=ol-51-13-3581"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,23]]},"references-count":27,"journal-issue":{"issue":"13","published-online":{"date-parts":[[2026]]},"published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.1364\/ol.597379","relation":{},"ISSN":["0146-9592","1539-4794"],"issn-type":[{"value":"0146-9592","type":"print"},{"value":"1539-4794","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,23]]},"assertion":[{"value":"Optica Publishing Group","name":"publisher","label":"This article is maintained by"},{"value":"https:\/\/doi.org\/10.1364\/OL.597379","name":"articlelink","label":"Crossref DOI link to publisher maintained version"},{"value":"letter","name":"content_type","label":"Article type"},{"value":"Screened by Similarity Check","name":"cross_check","label":"Similarity check"},{"value":"Yes","order":0,"name":"peer_reviewed","label":"Peer reviewed","group":{"name":"peer_review","label":"Peer review"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review process","group":{"name":"peer_review","label":"Peer review"}},{"value":"9 March 2026","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"28 May 2026","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"23 June 2026","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2026 Optica Publishing Group. All rights, including\n\t\t\t\t\tfor text and data mining (TDM), Artificial Intelligence (AI) training,\n\t\t\t\t\tand similar technologies, are reserved.","name":"copyright","label":"Copyright"}]}}