{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:50:33Z","timestamp":1792788633937,"version":"4.5.0"},"reference-count":18,"publisher":"Optica Publishing Group","issue":"20","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1364\/OA_License_v2#VOR"},{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/opg.optica.org\/policies\/opg-tdm-policy.json"}],"funder":[{"name":"Qinghai University Research Ability\n\t\t\t\t\t\tEnhancement Project","award":["2026KTSQ05"],"award-info":[{"award-number":["2026KTSQ05"]}]}],"content-domain":{"domain":["opg.optica.org"],"crossmark-restriction":false},"short-container-title":["Opt. Lett."],"published-print":{"date-parts":[[2026,10,15]]},"abstract":"<jats:p>Diffraction-based quantitative phase microscopy (QPM) conventionally\n\t\t\t\t\trequires stringent numerical aperture (NA) matching between\n\t\t\t\t\tillumination and objective lens (OL). We propose\n\t\t\t\t\thigh-spatiotemporal-resolution QPM under unmatched illumination\n\t\t\t\t\t(HSR-QPM-UI) that fully eliminates this constraint. By introducing a\n\t\t\t\t\t0.5\u03c0 phase shift exclusively to the non-scattered components of object\n\t\t\t\t\twaves under symmetric unmatched illumination, we physically encode\n\t\t\t\t\tlow-frequency phase information into intensity variations. A rigorous\n\t\t\t\t\tlinear forward model and an explicit phase transfer function are\n\t\t\t\t\tderived, enabling non-iterative phase retrieval via frequency-adaptive\n\t\t\t\t\tdeconvolution, achieving &gt;700-fold reconstruction speedup over\n\t\t\t\t\titerative methods. A shared phase modulation strategy permits\n\t\t\t\t\tacquisition speed limited only by the camera exposure time. The\n\t\t\t\t\tspatial light modulator (SLM)-based aberration compensation ensures\n\t\t\t\t\trobustness in real systems. Simulations and experiments collectively\n\t\t\t\t\tdemonstrate the superior phase imaging performance of HSR-QPM-UI. This\n\t\t\t\t\tapproach opens new avenues for high-throughput, real-time, label-free,\n\t\t\t\t\tand high-resolution quantitative phase imaging.<\/jats:p>","DOI":"10.1364\/ol.610597","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T13:42:01Z","timestamp":1791466921000},"page":"5866","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["High-spatiotemporal-resolution quantitative phase microscopy under unmatched illumination"],"prefix":"10.1364","volume":"51","author":[{"given":"Ying","family":"Ma","sequence":"first","affiliation":[{"name":"Qinghai University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunfei","family":"Ma","sequence":"additional","affiliation":[{"name":"Qinghai University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taiqiang","family":"Dai","sequence":"additional","affiliation":[{"name":"The Fourth Military Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haixin","family":"Xue","sequence":"additional","affiliation":[{"name":"Qinghai University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulian","family":"Han","sequence":"additional","affiliation":[{"name":"Qinghai University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengting","family":"Ma","sequence":"additional","affiliation":[{"name":"Qinghai University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Liu","sequence":"additional","affiliation":[{"name":"The Open University of Shaanxi"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2026,10,14]]},"reference":[{"key":"ol-51-20-5866-R1","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1038\/s41377-024-01619-7","type":"journal-article","volume":"13","author":"Chaumet","year":"2024","journal-title":"Light Sci.\n\t\t\t\t\tAppl."},{"key":"ol-51-20-5866-R2","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1038\/s41377-024-01460-y","type":"journal-article","volume":"13","author":"Huang","year":"2024","journal-title":"Light Sci. 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All rights, including\n\t\t\t\t\tfor text and data mining (TDM), Artificial Intelligence (AI) training,\n\t\t\t\t\tand similar technologies, are reserved.","name":"copyright","label":"Copyright"}]}}