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RT-PCR detected mRNA expression of TREK-1 in the carotid body. Furthermore, in situ hybridization revealed the localization of TREK-1 mRNA in the glomus cells. TREK-1 immunoreactivity was mainly distributed in the glomus cells and nerve fibers in the carotid body. TREK-1 may modulate potassium current of glomus cells and\/or afferent nerve endings in the rat carotid body.<\/jats:p>","DOI":"10.1369\/jhc.5a6755.2005","type":"journal-article","created":{"date-parts":[[2005,12,12]],"date-time":"2005-12-12T20:50:23Z","timestamp":1134420623000},"page":"467-472","source":"Crossref","is-referenced-by-count":18,"title":["Expression of Tandem P Domain K\n                    <sup>+<\/sup>\n                    Channel, TREK-1, in the Rat Carotid Body"],"prefix":"10.1177","volume":"54","author":[{"given":"Y.","family":"Yamamoto","sequence":"first","affiliation":[{"name":"Laboratory of Veterinary Anatomy, Faculty of Agriculture, Iwate University, Morioka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Taniguchi","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Anatomy, Faculty of Agriculture, Iwate University, Morioka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2006,4,1]]},"reference":[{"key":"bibr1-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2004.077503"},{"key":"bibr2-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.2000.00135.x"},{"key":"bibr3-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2004.076240"},{"key":"bibr4-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2002.035998"},{"key":"bibr5-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/cdg528"},{"key":"bibr6-jhc.5A6755.2005","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/S0026-895X(24)26499-3","volume":"57","author":"Duprat F","year":"2000","journal-title":"Mol Pharmacol"},{"key":"bibr7-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M010357200"},{"key":"bibr8-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(01)00030-6"},{"key":"bibr9-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2003.10.008"},{"key":"bibr10-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M108125200"},{"key":"bibr11-jhc.5A6755.2005","first-page":"315","volume-title":"Anatomic-Endocrine Interactions","author":"Kummer W","year":"1997"},{"key":"bibr12-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/19.8.1784"},{"key":"bibr13-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1016\/S0028-3908(02)00339-8"},{"key":"bibr14-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.275.14.10128"},{"key":"bibr15-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-328X(01)00129-2"},{"key":"bibr16-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-328X(00)00263-1"},{"key":"bibr17-jhc.5A6755.2005","first-page":"31","volume":"548","author":"Miller P","year":"2003","journal-title":"J Physiol"},{"key":"bibr18-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00334.2003"},{"key":"bibr19-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1994.sp020229"},{"key":"bibr20-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000027440.68031.B0"},{"key":"bibr21-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4615-2966-8_27"},{"key":"bibr22-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2002.018382"},{"key":"bibr23-jhc.5A6755.2005","doi-asserted-by":"crossref","first-page":"535","DOI":"10.55782\/ane-1996-1157","volume":"56","author":"Strosznajder RP","year":"1996","journal-title":"Acta Neurobiol Exp (Wars)"},{"key":"bibr24-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.21-19-07491.2001"},{"key":"bibr25-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.2003.027052"},{"key":"bibr26-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1016\/0197-0186(95)00130-1"},{"key":"bibr27-jhc.5A6755.2005","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(02)03181-5"}],"container-title":["Journal of Histochemistry &amp; 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