{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T12:26:54Z","timestamp":1774787214668,"version":"3.50.1"},"reference-count":28,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2005,6,24]],"date-time":"2005-06-24T00:00:00Z","timestamp":1119571200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.ploscompbiol.org"],"crossmark-restriction":false},"short-container-title":["PLoS Comput Biol"],"DOI":"10.1371\/journal.pcbi.0010007","type":"journal-article","created":{"date-parts":[[2005,6,24]],"date-time":"2005-06-24T17:29:50Z","timestamp":1119634190000},"page":"e7","update-policy":"https:\/\/doi.org\/10.1371\/journal.pcbi.corrections_policy","source":"Crossref","is-referenced-by-count":21,"title":["Susceptibility to Superhelically Driven DNA Duplex Destabilization: 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origins.\n\t\t\t\t\tScience\n\t\t\t\t\t294\n\t\t\t\t\t2357\n\t\t\t\t\t2360","DOI":"10.1126\/science.1066101"},{"key":"pcbi-0010007-b23","doi-asserted-by":"crossref","unstructured":"Raghuraman\n\t\t\t\t\t\t\tMK\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tWinzeler\n\t\t\t\t\t\t\tEA\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tCollingwood\n\t\t\t\t\t\t\tD\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tHunt\n\t\t\t\t\t\t\tS\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tWodicka\n\t\t\t\t\t\t\tL\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\t2001\n\t\t\t\t\tReplication dynamics of the yeast genome.\n\t\t\t\t\tScience\n\t\t\t\t\t294\n\t\t\t\t\t115\n\t\t\t\t\t121","DOI":"10.1126\/science.294.5540.115"},{"key":"pcbi-0010007-b24","doi-asserted-by":"crossref","unstructured":"Breier\n\t\t\t\t\t\t\tAM\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tChatterji\n\t\t\t\t\t\t\tS\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tCozzarelli\n\t\t\t\t\t\t\tNR\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\t2004\n\t\t\t\t\tPrediction of Saccharomyces cerevisiae replication origins.\n\t\t\t\t\tGenome Biol\n\t\t\t\t\t5\n\t\t\t\t\tR22","DOI":"10.1186\/gb-2004-5-4-r22"},{"key":"pcbi-0010007-b25","unstructured":"Stanford University School of Medicine Department of Genetics\n\t\t\t\t\t2004\n\t\t\t\t\tSaccharomyces Genome Database [database]\n\t\t\t\t\tAvailable: http:\/\/www.yeastgenome.org\/. Accessed 19 May 2005."},{"key":"pcbi-0010007-b26","doi-asserted-by":"crossref","unstructured":"Kowalski\n\t\t\t\t\t\t\tD\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tNatale\n\t\t\t\t\t\t\tDA\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tEddy\n\t\t\t\t\t\t\tMJ\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\t1988\n\t\t\t\t\tStable DNA unwinding, not \u201cbreathing,\u201d accounts for single-strand-specific nuclease hypersensitivity of specific A+T-rich sequences.\n\t\t\t\t\tProc Natl Acad Sci U S A\n\t\t\t\t\t85\n\t\t\t\t\t9464\n\t\t\t\t\t9468","DOI":"10.1073\/pnas.85.24.9464"},{"key":"pcbi-0010007-b27","doi-asserted-by":"crossref","unstructured":"Kouzine\n\t\t\t\t\t\t\tF\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLiu\n\t\t\t\t\t\t\tJ\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSanford\n\t\t\t\t\t\t\tS\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tChung\n\t\t\t\t\t\t\tHJ\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLevens\n\t\t\t\t\t\t\tD\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\t2004\n\t\t\t\t\tThe dynamic response of upstream DNA to transcription-generated torsional stress.\n\t\t\t\t\tNat Struct Mol Biol\n\t\t\t\t\t11\n\t\t\t\t\t1092\n\t\t\t\t\t1100","DOI":"10.1038\/nsmb848"},{"key":"pcbi-0010007-b28","doi-asserted-by":"crossref","unstructured":"Zaret\n\t\t\t\t\t\t\tKS\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSherman\n\t\t\t\t\t\t\tF\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\t1982\n\t\t\t\t\tDNA sequence required for efficient transcription termination in yeast.\n\t\t\t\t\tCell\n\t\t\t\t\t28\n\t\t\t\t\t563\n\t\t\t\t\t573","DOI":"10.1016\/0092-8674(82)90211-2"}],"container-title":["PLoS Computational Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pcbi.0010007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T17:26:15Z","timestamp":1588785975000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pcbi.0010007"}},"subtitle":[],"editor":[{"given":"Philip","family":"Bourne","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2005,6,24]]},"references-count":28,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2005,6,24]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pcbi.0010007","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1027645.335714","asserted-by":"object"}]},"ISSN":["1553-7358"],"issn-type":[{"value":"1553-7358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,6,24]]}}}