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Sacks","year":"1982","journal-title":"J Morphol"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0966-6362(96)82849-9","article-title":"Human balance and posture control during standing and walking.","volume":"3","author":"DA Winter","year":"1995","journal-title":"Gait Posture"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/s00221-003-1464-y","article-title":"Differential activation of neuromuscular compartments in the rabbit masseter muscle during different oral behaviors.","volume":"150","author":"CG Widmer","year":"2003","journal-title":"Exp Brain Res"},{"key":"ref52","doi-asserted-by":"crossref","DOI":"10.1002\/9780470316894","article-title":"Statistical Factor Analysis and Related Methods: Theory and Applications","author":"A Basilevsky","year":"1994"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1152\/jn.1994.71.3.931","article-title":"Changes in a postural strategy with inter-paw 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Res"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.jphysparis.2009.08.001","article-title":"Comparison of human and humanoid robot control of upright stance.","volume":"103","author":"RJ Peterka","year":"2009","journal-title":"J Physiol Paris"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1152\/jn.2002.88.3.1097","article-title":"Sensorimotor integration in human postural control.","volume":"88","author":"RJ Peterka","year":"2002","journal-title":"J Neurophysiol"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s004220050587","article-title":"Postural control model interpretation of stabilogram diffusion analysis.","volume":"82","author":"RJ Peterka","year":"2000","journal-title":"Biol Cybern"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1162\/089976602753712918","article-title":"Cosine tuning minimizes motor errors.","volume":"14","author":"E Todorov","year":"2002","journal-title":"Neural Comput"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.jbiomech.2009.10.009","article-title":"Modular control of human walking: Adaptations to altered mechanical demands.","volume":"43","author":"CP McGowan","year":"2010","journal-title":"J Biomech"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1016\/j.jbiomech.2009.03.009","article-title":"Modular control of human walking: A simulation study.","volume":"42","author":"RR Neptune","year":"2009","journal-title":"J Biomech"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1152\/jn.01054.2007","article-title":"A Simple Experimentally Based Model Using Proprioceptive Regulation of Motor Primitives Captures Adjusted Trajectory Formation in Spinal Frogs.","volume":"103","author":"WJ Kargo","year":"2010","journal-title":"J Neurophysiol"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"7601","DOI":"10.1073\/pnas.0901512106","article-title":"Simplified and effective motor control based on muscle synergies to exploit musculoskeletal dynamics.","volume":"106","author":"M Berniker","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"2320","DOI":"10.1162\/neco.2006.18.10.2320","article-title":"Properties of synergies arising from a theory of optimal motor behavior.","volume":"18","author":"M Chhabra","year":"2006","journal-title":"Neural Comput"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1038\/nn963","article-title":"Optimal feedback control as a theory of motor coordination.","volume":"5","author":"E Todorov","year":"2002","journal-title":"Nat Neurosci"},{"key":"ref67","first-page":"50","article-title":"IEEE Symposium on Adaptive Dynamic Programming And Reinforcement Learning (ADPRL)","author":"D Liu","year":"2009","journal-title":"IEEE Symposium on Adaptive Dynamic Programming And Reinforcement Learning (ADPRL)"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1002\/rob.20093","article-title":"From task parameters to motor synergies: A hierarchical framework for approximately-optimal control of redundant manipulators.","volume":"22","author":"E Todorov","year":"2005","journal-title":"J Robot Syst"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/BF00237855","article-title":"Fixed patterns of rapid postural responses among leg muscles during stance.","volume":"30","author":"LM Nashner","year":"1977","journal-title":"Exp Brain Res"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/0304-3940(89)90014-1","article-title":"Compensation of translational and rotational perturbations in human posture: stabilization of the centre of gravity.","volume":"105","author":"A Gollhofer","year":"1989","journal-title":"Neurosci Lett"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s002210050940","article-title":"Directional sensitivity of stretch reflexes and balance corrections for normal subjects in the roll and pitch planes.","volume":"129","author":"MG Carpenter","year":"1999","journal-title":"Exp Brain Res"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1109\/10.362914","article-title":"An optimal control model for analyzing human postural balance.","volume":"42","author":"AD Kuo","year":"1995","journal-title":"IEEE Trans Biomed Eng"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"9431","DOI":"10.1523\/JNEUROSCI.5537-09.2010","article-title":"Spinal-like regulator facilitates control of a two-degree-of-freedom wrist.","volume":"30","author":"G Raphael","year":"2010","journal-title":"J 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in an isometric pushing task: prediction by kinematic and musculoskeletal models.","volume":"150","author":"MW Schmidt","year":"2003","journal-title":"Exp Brain Res"},{"key":"ref78","first-page":"1620","article-title":"Biped walking pattern generation by using preview control of zero-moment point.","author":"S Kajita","year":"2003"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1109\/ROBOT.1999.770006","article-title":"Development of a Bipedal Humanoid Robot-Control Method of Whole Body Cooperative Dynamic Biped Walking.","author":"J Yamaguchi","year":"1999","journal-title":"Proceedings of the IEEE International Conference on Robotics & Automation"},{"key":"ref80","first-page":"163","article-title":"Angular momentum primitives for human turning: Control implications for biped robots.","author":"MT Farrell","year":"2008","journal-title":"Proceedings of the 8"},{"key":"ref81","first-page":"Article 74","article-title":"Optimal Feedback Control for Character Animation Using an Abstract Model.","volume":"29","author":"Y Ye","year":"2010","journal-title":"ACM Trans Graph (SIGGRAPH)"},{"key":"ref82","first-page":"167","article-title":"The Reaction Mass Pendulum (RMP) Model for Humanoid Robot Gait and Balance Control.","volume":"71","author":"S-H Lee","year":"2009","journal-title":"Humanoid Robots"},{"key":"ref83","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1242\/jeb.008573","article-title":"Angular momentum in human walking.","volume":"211","author":"H Herr","year":"2008","journal-title":"J Exp Biol"},{"key":"ref84","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.jbiomech.2010.08.015","article-title":"Muscle contributions to whole-body sagittal plane angular momentum during walking.","volume":"44","author":"RR Neptune","year":"2011","journal-title":"J Biomech"},{"key":"ref85","first-page":"1685","article-title":"Angular momentum primitives for human walking: biomechanics and control.","author":"M Popovic","year":"2004"},{"key":"ref86","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0021-9290(94)00072-C","article-title":"The redundant nature of locomotor optimization laws.","volume":"28","author":"JJ Collins","year":"1995","journal-title":"J Biomech"},{"key":"ref87","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s00285-009-0306-3","article-title":"An analytical approach to the problem of inverse optimization with additive objective functions: an application to human prehension.","volume":"61","author":"AV Terekhov","year":"2009","journal-title":"J Math Biol"},{"key":"ref88","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1145\/1073204.1073314","article-title":"Learning physics-based motion style with nonlinear inverse optimization.","volume":"24","author":"CK Liu","year":"2005","journal-title":"ACM Trans Graph (SIGGRAPH)"},{"key":"ref89","doi-asserted-by":"crossref","first-page":"e1002183","DOI":"10.1371\/journal.pcbi.1002183","article-title":"Evidence for Composite Cost Functions in Arm Movement Planning: An Inverse Optimal Control Approach.","volume":"7","author":"B Berret","year":"2011","journal-title":"PLoS Comput Biol"},{"key":"ref90","doi-asserted-by":"crossref","first-page":"4244","DOI":"10.1152\/jn.00404.2005","article-title":"Optimal Control of Redundant Muscles in Step-Tracking Wrist Movements.","volume":"94","author":"M Haruno","year":"2005","journal-title":"J Neurophysiol"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/0021-9290(88)90249-7","article-title":"Estimated mechanical properties of synergistic muscles involved in movements of a variety of human joints.","volume":"21","author":"JM Winters","year":"1988","journal-title":"J Biomech"},{"key":"ref92","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1093\/ptj\/73.12.830","article-title":"Motor unit recruitment and the gradation of muscle force.","volume":"73","author":"HP Clamann","year":"1993","journal-title":"Phys Ther"},{"key":"ref93","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1038\/35106566","article-title":"The central nervous system stabilizes unstable dynamics by learning optimal impedance.","volume":"414","author":"E Burdet","year":"2001","journal-title":"Nature"},{"key":"ref94","article-title":"Infinite-horizon optimal control framework for goal-directed movements [Abstract].","author":"D Huh","year":"2010"},{"key":"ref95","doi-asserted-by":"crossref","first-page":"10507","DOI":"10.1523\/JNEUROSCI.1343-10.2010","article-title":"Temporal Discounting of Reward and the Cost of Time in Motor Control.","volume":"30","author":"R Shadmehr","year":"2010","journal-title":"J Neurosci"},{"key":"ref96","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s00422-006-0064-x","article-title":"The Main Sequence of Saccades Optimizes Speed-accuracy Trade-off.","volume":"95","author":"CM Harris","year":"2006","journal-title":"Biol Cybern"},{"key":"ref97","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1002\/jmor.10233","article-title":"Three-dimensional model of the feline hindlimb.","volume":"261","author":"TJ Burkholder","year":"2004","journal-title":"Journal of Morphology"},{"key":"ref98","article-title":"Neuromechanical Constraints and Optimality for Balance","author":"JL McKay","year":"2010"},{"key":"ref99","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s00221-008-1280-5","article-title":"A computational neuroanatomy for motor control.","volume":"185","author":"R Shadmehr","year":"2008","journal-title":"Exp Brain Res"},{"key":"ref100","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1523\/JNEUROSCI.02-11-01527.1982","article-title":"On the Relations between the Direction of Two-Dimensional Arm Movements and Cell Discharge in Primate Motor Cortex.","volume":"2","author":"AP Georgopoulos","year":"1982","journal-title":"J Neurosci"},{"key":"ref101","doi-asserted-by":"crossref","first-page":"2913","DOI":"10.1523\/JNEUROSCI.08-08-02913.1988","article-title":"Primate motor cortex and free arm movements to visual targets in three- dimensional space. I. Relations between single cell discharge and direction of movement.","volume":"8","author":"AB Schwartz","year":"1988","journal-title":"J Neurosci"},{"key":"ref102","first-page":"00764.02009","article-title":"The decerebrate cat generates the essential features of the force constraint strategy.","author":"CF Honeycutt","year":"2010","journal-title":"J Neurophysiol"},{"key":"ref103","doi-asserted-by":"crossref","first-page":"2751","DOI":"10.1152\/jn.91040.2008","article-title":"Electromyographic Responses From the Hindlimb Muscles of the Decerebrate Cat to Horizontal Support Surface Perturbations.","volume":"101","author":"CF Honeycutt","year":"2009","journal-title":"J Neurophysiol"},{"key":"ref104","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1152\/jn.01381.2007","article-title":"Neurons in the Pontomedullary Reticular Formation Signal Posture and Movement Both as an Integrated Behavior and Independently.","volume":"100","author":"B Schepens","year":"2008","journal-title":"J Neurophysiol"},{"key":"ref105","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1152\/jn.91013.2008","article-title":"The Pontomedullary Reticular Formation Contributes to the Compensatory Postural Responses Observed Following Removal of the Support Surface in the Standing Cat.","volume":"101","author":"PJ Stapley","year":"2009","journal-title":"J Neurophysiol"},{"key":"ref106","doi-asserted-by":"crossref","first-page":"S168","DOI":"10.1088\/1741-2560\/4\/3\/S04","article-title":"Limb-state feedback from ensembles of simultaneously recorded dorsal root ganglion neurons.","volume":"4","author":"DJ Weber","year":"2007","journal-title":"J Neural Eng"},{"key":"ref107","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1152\/jn.00022.2001","article-title":"Independent representations of limb axis length and orientation in spinocerebellar response components.","volume":"87","author":"RE Poppele","year":"2002","journal-title":"J Neurophysiol"},{"key":"ref108","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1152\/jn.1986.55.3.425","article-title":"Multiple Axon Collaterals of Single Corticospinal Axons in the Cat Spinal-Cord.","volume":"55","author":"Y Shinoda","year":"1986","journal-title":"J Neurophysiol"},{"key":"ref109","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1152\/jn.1980.44.4.751","article-title":"Postspike facilitation of forelimb muscle activity by primate corticomotoneuronal cells.","volume":"44","author":"EE Fetz","year":"1980","journal-title":"J Neurophysiol"},{"key":"ref110","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s00221-002-1166-x","article-title":"Primary motor cortical neurons encode functional muscle synergies.","volume":"146","author":"RN Holdefer","year":"2002","journal-title":"Exp Brain Res"},{"key":"ref111","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1152\/jn.00469.2010","article-title":"Sequential Activation of Motor Cortical Neurons Contributes to Intralimb Coordination During Reaching in the Cat by Modulating Muscle Synergies.","volume":"105","author":"S Yakovenko","year":"2011","journal-title":"J Neurophysiol"},{"key":"ref112","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1073\/pnas.0808362106","article-title":"Subdivisions of primary motor cortex based on cortico-motoneuronal cells.","volume":"106","author":"JA Rathelot","year":"2009","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"ref113","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1523\/JNEUROSCI.5894-08.2010","article-title":"A neural basis for motor primitives in the spinal cord.","volume":"30","author":"CB Hart","year":"2010","journal-title":"J Neurosci"},{"key":"ref114","article-title":"The Coordination and Regulation of Movements","author":"N Bernstein","year":"1967"},{"key":"ref115","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.conb.2004.07.007","article-title":"Sparse coding of sensory inputs.","volume":"14","author":"BA Olshausen","year":"2004","journal-title":"Curr Opin Neurobiol"},{"key":"ref116","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1080\/00222895.2010.526453","article-title":"Modularity for sensorimotor control: evidence and a new prediction.","volume":"42","author":"A d'Avella","year":"2010","journal-title":"J Mot Behav"},{"key":"ref117","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.conb.2009.09.002","article-title":"The case for and against muscle synergies.","volume":"19","author":"MC Tresch","year":"2009","journal-title":"Curr Opin Neurobiol"},{"key":"ref118","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/BF00275687","article-title":"Simplified neuron model as a principal component analyzer.","volume":"15","author":"E Oja","year":"1982","journal-title":"J Math Biol"},{"key":"ref119","doi-asserted-by":"crossref","first-page":"3570","DOI":"10.1016\/j.jbiomech.2007.06.001","article-title":"Inter-joint coupling effects on muscle contributions to endpoint force and acceleration in a musculoskeletal model of the cat hindlimb.","volume":"40","author":"KW van Antwerp","year":"2007","journal-title":"J Biomech"},{"key":"ref120","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1152\/jn.01058.2009","article-title":"Motor Memory and Local Minimization of Error and Effort, Not Global Optimization, Determine Motor Behavior.","volume":"104","author":"G Ganesh","year":"2010","journal-title":"J Neurophysiol"}],"container-title":["PLoS Computational 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