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In: Century-Crofts N-YA, editor. Classical conditioning II: Current research and Theory: Black A.H, P.W.H."},{"key":"ref12","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1037\/0033-295X.87.6.532","article-title":"A model for Pavlovian learning: variations in the effectiveness of conditioned but not of unconditioned stimuli","volume":"87","author":"JM Pearce","year":"1980","journal-title":"Psychol Rev"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1038\/nn.2904","article-title":"Differential roles of human striatum and amygdala in associative learning","volume":"14","author":"J Li","year":"2011","journal-title":"Nat Neurosci"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0959-4388(00)00078-7","article-title":"Classical fear conditioning in functional neuroimaging","volume":"10","author":"C Buchel","year":"2000","journal-title":"Curr Opin 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