{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T04:39:49Z","timestamp":1774931989695,"version":"3.50.1"},"reference-count":111,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2013,3,7]],"date-time":"2013-03-07T00:00:00Z","timestamp":1362614400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.ploscompbiol.org"],"crossmark-restriction":false},"short-container-title":["PLoS Comput Biol"],"DOI":"10.1371\/journal.pcbi.1002937","type":"journal-article","created":{"date-parts":[[2013,3,7]],"date-time":"2013-03-07T21:55:46Z","timestamp":1362693346000},"page":"e1002937","update-policy":"https:\/\/doi.org\/10.1371\/journal.pcbi.corrections_policy","source":"Crossref","is-referenced-by-count":110,"title":["Trade-off between Multiple Constraints Enables Simultaneous Formation of Modules and Hubs in Neural Systems"],"prefix":"10.1371","volume":"9","author":[{"given":"Yuhan","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengjun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claus C.","family":"Hilgetag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changsong","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2013,3,7]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/0165-0173(94)00016-I","article-title":"Large-scale cortical networks and cognition","volume":"20","author":"S Bressler","year":"1995","journal-title":"Brain Research Reviews"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1093\/brain\/121.6.1013","article-title":"From sensation to cognition","volume":"121","author":"M Mesulam","year":"1998","journal-title":"Brain"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/S0893-6080(00)00059-9","article-title":"Towards a network theory of cognition","volume":"13","author":"A McIntosh","year":"2000","journal-title":"Neural Networks"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1146\/annurev.neuro.25.112701.142846","article-title":"Beyond phrenology: what can neuroimaging tell us about distributed circuitry?","volume":"25","author":"K Friston","year":"2002","journal-title":"Annual review of neuroscience"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Buzs\u00e1ki G (2006) Rhythms of the Brain. USA: Oxford University Press.","DOI":"10.1093\/acprof:oso\/9780195301069.001.0001"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.tics.2004.07.008","article-title":"Organization, development and function of complex brain networks","volume":"8","author":"O Sporns","year":"2004","journal-title":"Trends in Cognitive Sciences"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1177\/1073858406293182","article-title":"Small-world brain networks","volume":"12","author":"D Bassett","year":"2006","journal-title":"The Neuroscientist"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"238103","DOI":"10.1103\/PhysRevLett.97.238103","article-title":"Hierarchical organization unveiled by functional connectivity in complex brain networks","volume":"97","author":"C Zhou","year":"2006","journal-title":"Physical review letters"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.physd.2006.09.008","article-title":"Structural and functional clusters of complex brain networks","volume":"224","author":"L Zemanov\u00e1","year":"2006","journal-title":"Physica D: Nonlinear Phenomena"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"10240","DOI":"10.1073\/pnas.0701519104","article-title":"Network structure of cerebral cortex shapes functional connectivity on multiple time scales","volume":"104","author":"C Honey","year":"2007","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.tins.2007.04.004","article-title":"The topographic brain: from neural connectivity to cognition","volume":"30","author":"J Thivierge","year":"2007","journal-title":"Trends in Neurosciences"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1016\/j.clinph.2007.08.010","article-title":"The application of graph theoretical analysis to complex networks in the brain","volume":"118","author":"J Reijneveld","year":"2007","journal-title":"Clinical Neurophysiology"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1753-4631-1-3","article-title":"Graph theoretical analysis of complex networks in the brain","volume":"1","author":"C Stam","year":"2007","journal-title":"Nonlinear Biomedical Physics"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1038\/nrn2575","article-title":"Complex brain networks: graph theoretical analysis of structural and functional systems","volume":"10","author":"E Bullmore","year":"2009","journal-title":"Nat Rev Neurosci"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.neuroimage.2010.01.071","article-title":"Can structure predict function in the human brain?","volume":"52","author":"C Honey","year":"2010","journal-title":"Neuroimage"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3389\/fnins.2011.00083","article-title":"Exploring brain function from anatomical connectivity","volume":"5","author":"G Zamora-L\u00f3pez","year":"2011","journal-title":"Front Neurosci"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1038\/30918","article-title":"Collective dynamics of small-worldnetworks","volume":"393","author":"D Watts","year":"1998","journal-title":"Nature"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1093\/cercor\/bhj127","article-title":"Small-world networks and functional connectivity in alzheimer&apos;s disease","volume":"17","author":"C Stam","year":"2007","journal-title":"Cerebral Cortex"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1093\/brain\/awn018","article-title":"Disrupted small-world networks in schizophrenia","volume":"131","author":"Y Liu","year":"2008","journal-title":"Brain"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"e1049","DOI":"10.1371\/journal.pone.0001049","article-title":"Identification and classification of hubs in brain networks","volume":"2","author":"O Sporns","year":"2007","journal-title":"PLoS One"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"e159","DOI":"10.1371\/journal.pbio.0060159","article-title":"Mapping the structural core of human cerebral cortex","volume":"6","author":"P Hagmann","year":"2008","journal-title":"PLoS Biology"},{"key":"ref22","first-page":"1","article-title":"Cortical hubs form a module for multisensory integration on top of the hierarchy of cortical networks","volume":"4","author":"G Zamora-L\u00f3pez","year":"2010","journal-title":"Frontiers in Neuroinformatics"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1038\/358152a0","article-title":"Objective analysis of the topological organization of the primate cortical visual system","volume":"358","author":"M Young","year":"1992","journal-title":"Nature"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1098\/rstb.2000.0551","article-title":"Anatomical connectivity defines the organization of clusters of cortical areas in the macaque monkey and the cat","volume":"355","author":"C Hilgetag","year":"2000","journal-title":"Phil Trans R Soc Lond B"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1385\/NI:2:3:353","article-title":"Clustered organization of cortical connectivity","volume":"2","author":"C Hilgetag","year":"2004","journal-title":"Neuroinformatics"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.physd.2006.09.008","article-title":"Structural and functional clusters of complex brain networks","volume":"224","author":"L Zemanov\u00e1","year":"2006","journal-title":"Physica D: Nonlinear Phenomena"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/1752-0509-1-16","article-title":"Predicting the connectivity of primate cortical networks from topological and spatial node properties","volume":"1","author":"L Costa","year":"2007","journal-title":"BMC Systems Biology"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"7821","DOI":"10.1073\/pnas.122653799","article-title":"Community structure in social and biological networks","volume":"99","author":"M Girvan","year":"2002","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1103\/RevModPhys.74.47","article-title":"Statistical mechanics of complex networks","volume":"74","author":"R Albert","year":"2002","journal-title":"Reviews of modern physics"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1126\/science.1073374","article-title":"Hierarchical organization of modularity in metabolic networks","volume":"297","author":"E Ravasz","year":"2002","journal-title":"Science"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/j.mri.2008.01.048","article-title":"Community structure and modularity in networks of correlated brain activity","volume":"26","author":"A Schwarz","year":"2008","journal-title":"Magnetic resonance imaging"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1002\/hbm.20663","article-title":"Hierarchical functional modularity in the resting-state human brain","volume":"30","author":"L Ferrarini","year":"2009","journal-title":"Human brain mapping"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.neuroimage.2008.09.062","article-title":"Age-related changes in modular organization of human brain functional networks","volume":"44","author":"D Meunier","year":"2009","journal-title":"Neuroimage"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1523\/JNEUROSCI.15-02-01463.1995","article-title":"Analysis of connectivity in the cat cerebral cortex","volume":"15","author":"J Scannell","year":"1995","journal-title":"The Journal of Neuroscience"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1098\/rspb.1993.0040","article-title":"The organization of neural systems in the primate cerebral cortex","volume":"252","author":"M Young","year":"1993","journal-title":"Proceedings of the Royal Society of London Series B: Biological Sciences"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"e9240","DOI":"10.1371\/journal.pone.0009240","article-title":"Mesoscopic organization reveals the constraints governing caenorhabditis elegans nervous system","volume":"5","author":"R Pan","year":"2010","journal-title":"PloS one"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"238701","DOI":"10.1103\/PhysRevLett.91.238701","article-title":"Network information and connected correlations","volume":"91","author":"E Schneidman","year":"2003","journal-title":"Physical review letters"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1038\/nature04701","article-title":"Weak pairwise correlations imply strongly correlated network states in a neural population","volume":"440","author":"E Schneidman","year":"2006","journal-title":"Nature"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"021915","DOI":"10.1103\/PhysRevE.75.021915","article-title":"Functional structure of cortical neuronal networks grown in vitro","volume":"75","author":"L Bettencourt","year":"2007","journal-title":"Physical Review E"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1098\/rstb.2005.1645","article-title":"Undirected graphs of frequencydependent functional connectivity in whole brain networks","volume":"360","author":"R Salvador","year":"2005","journal-title":"Philosophical Transactions of the Royal Society B: Biological Sciences"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"18102","DOI":"10.1103\/PhysRevLett.107.018102","article-title":"Geometric effects on complex network structure in the cortex","volume":"107","author":"J Henderson","year":"2011","journal-title":"Physical Review Letters"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"5868","DOI":"10.1073\/pnas.1111738109","article-title":"Simple models of human brain functional networks","volume":"109","author":"P V\u00e9rtes","year":"2012","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.neuroimage.2007.02.012","article-title":"Characterizing brain anatomical connections using diffusion weighted mri and graph theory","volume":"36","author":"Y Iturria-Medina","year":"2007","journal-title":"Neuroimage"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1016\/j.neuroimage.2007.10.060","article-title":"Studying the human brain anatomical network via diffusion-weighted mri and graph theory","volume":"40","author":"Y Iturria-Medina","year":"2008","journal-title":"Neuroimage"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1093\/cercor\/bhn102","article-title":"Mapping anatomical connectivity patterns of human cerebral cortex using in vivo diffusion tensor imaging tractography","volume":"19","author":"G Gong","year":"2009","journal-title":"Cerebral Cortex"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1523\/JNEUROSCI.3874-05.2006","article-title":"A resilient, low-frequency, small-world human brain functional network with highly connected association cortical hubs","volume":"26","author":"S Achard","year":"2006","journal-title":"The Journal of Neuroscience"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"e1001066","DOI":"10.1371\/journal.pcbi.1001066","article-title":"Structural properties of the caenorhabditis elegans neuronal network","volume":"7","author":"L Varshney","year":"2011","journal-title":"PLoS computational biology"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"4756","DOI":"10.1523\/JNEUROSCI.0141-08.2008","article-title":"Structural insights into aberrant topological patterns of large-scale cortical networks in alzheimer&apos;s disease","volume":"28","author":"Y He","year":"2008","journal-title":"The Journal of Neuroscience"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/236","article-title":"The metabolic cost of neural information","volume":"1","author":"S Laughlin","year":"1998","journal-title":"Nature neuroscience"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1126\/science.1089662","article-title":"Communication in neuronal networks","volume":"301","author":"S Laughlin","year":"2003","journal-title":"Science"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S0140525X06009010","article-title":"Pr\u00e9cis of principles of brain evolution","volume":"29","author":"G Striedter","year":"2006","journal-title":"Behavioral and Brain Sciences"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/nrn3214","article-title":"The economy of brain network organization","volume":"13","author":"E Bullmore","year":"2012","journal-title":"Nature Reviews Neuroscience"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1098\/rspb.1991.0102","article-title":"Neuronal branching patterns and the economy of cortical wiring","volume":"245","author":"G Mitchison","year":"1991","journal-title":"Proceedings of the Royal Society of London Series B: Biological Sciences"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1007\/BF00204115","article-title":"Local optimization of neuron arbors","volume":"66","author":"C Cherniak","year":"1992","journal-title":"Biological cybernetics"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"2418","DOI":"10.1523\/JNEUROSCI.14-04-02418.1994","article-title":"Component placement optimization in the brain","volume":"14","author":"C Cherniak","year":"1994","journal-title":"The Journal of neuroscience"},{"key":"ref56","doi-asserted-by":"crossref","unstructured":"Ram\u00f3n y Cajal S (1995) Histology of the nervous system of man and vertebrates. New York: Oxford University Press.","DOI":"10.1093\/oso\/9780195074017.001.0001"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/0166-2236(95)98373-7","article-title":"Neural component placement","volume":"18","author":"C Cherniak","year":"1995","journal-title":"Trends in neurosciences"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0896-6273(02)00679-7","article-title":"Wiring optimization in cortical circuits","volume":"34","author":"D Chklovskii","year":"2002","journal-title":"Neuron"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"7937","DOI":"10.1073\/pnas.0932745100","article-title":"Connectivity optimization and the positioning of cortical areas","volume":"100","author":"V Klyachko","year":"2003","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.tins.2004.02.007","article-title":"Interneuron diversity series: circuit complexity and axon wiring economy of cortical interneurons","volume":"27","author":"G Buzsaki","year":"2004","journal-title":"TRENDS in Neurosciences"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1146\/annurev.neuro.27.070203.144226","article-title":"Maps in the brain: What can we learn from them?","volume":"27","author":"D Chklovskii","year":"2004","journal-title":"Annu Rev Neurosci"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1162\/0899766041732422","article-title":"Exact solution for the optimal neuronal layout problem","volume":"16","author":"D Chklovskii","year":"2004","journal-title":"Neural computation"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"e95","DOI":"10.1371\/journal.pcbi.0020095","article-title":"Nonoptimal component placement, but short processing paths, due to long-distance projections in neural systems","volume":"2","author":"M Kaiser","year":"2006","journal-title":"PLoS Comput Biol"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1073\/pnas.0305212101","article-title":"Global optimization of cerebral cortex layout","volume":"101","author":"C Cherniak","year":"2004","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"4723","DOI":"10.1073\/pnas.0506806103","article-title":"Wiring optimization can relate neuronal structure and function","volume":"103","author":"B Chen","year":"2006","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.physa.2005.12.013","article-title":"Wiring cost in the organization of a biological neuronal network","volume":"367","author":"Y Ahn","year":"2006","journal-title":"Physica A: Statistical Mechanics and its Applications"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"3033","DOI":"10.1098\/rsta.2007.0007","article-title":"Brain architecture: a design for natural computation","volume":"365","author":"M Kaiser","year":"2007","journal-title":"Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"e1000711","DOI":"10.1371\/journal.pcbi.1000711","article-title":"Neocortical axon arbors trade-off material and conduction delay conservation","volume":"6","author":"J Budd","year":"2010","journal-title":"PLoS Comput Biol"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"17180","DOI":"10.1073\/pnas.0703183104","article-title":"Optimally wired subnetwork determines neuroanatomy of caenorhabditis elegans","volume":"104","author":"A P\u00e9rez-Escudero","year":"2007","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"ref70","first-page":"519","article-title":"A wire length minimization approach","volume":"29","author":"A Koulakov","year":"2001","journal-title":"Neuron"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"3674","DOI":"10.1103\/PhysRevLett.86.3674","article-title":"Optimal wiring principle and plateaus in the degree of separation for cortical neurons","volume":"86","author":"J Karbowski","year":"2001","journal-title":"Physical review letters"},{"key":"ref72","doi-asserted-by":"crossref","unstructured":"Hilgetag C, Kaiser M (2008) Organization and function of complex cortical networks. In: Lectures in Supercomputational Neuroscience: Dynamics in Complex Brain. pp. 107\u2013133.","DOI":"10.1007\/978-3-540-73159-7_4"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S0165-0173(00)00038-2","article-title":"Cns energy metabolism as related to function","volume":"34","author":"A Ames","year":"2000","journal-title":"Brain Research Reviews"},{"key":"ref74","doi-asserted-by":"crossref","unstructured":"Von Der Malsburg C (1994) The correlation theory of brain function. In: Models of neural networks II: Temporal Aspects of Coding and Information Processing in Biological Systems. Springer Verlag. pp. 95\u2013119.","DOI":"10.1007\/978-1-4612-4320-5_2"},{"key":"ref75","unstructured":"Destexhe A, Sejnowski T (2001) Thalamocortical assemblies. Oxford: Oxford University Press."},{"key":"ref76","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1038\/35086012","article-title":"Correlated neuronal activity and the flow of neural information","volume":"2","author":"E Salinas","year":"2001","journal-title":"Nature reviews Neuroscience"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1007\/s00422-004-0471-9","article-title":"Global and local synchrony of coupled neurons in small-world networks","volume":"90","author":"N Masuda","year":"2004","journal-title":"Biological cybernetics"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1038\/nrn2258","article-title":"Noise in the nervous system","volume":"9","author":"A Faisal","year":"2008","journal-title":"Nature Reviews Neuroscience"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"11747","DOI":"10.1073\/pnas.0903641106","article-title":"Cognitive fitness of cost-efficient brain functional networks","volume":"106","author":"D Bassett","year":"2009","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"7619","DOI":"10.1523\/JNEUROSCI.1443-09.2009","article-title":"Efficiency of functional brain networks and intellectual performance","volume":"29","author":"M van den Heuvel","year":"2009","journal-title":"The Journal of Neuroscience"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"e1000395","DOI":"10.1371\/journal.pcbi.1000395","article-title":"Brain anatomical network and intelligence","volume":"5","author":"Y Li","year":"2009","journal-title":"PLoS computational biology"},{"key":"ref82","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nrn2793","article-title":"The neuroscience of human intelligence differences","volume":"11","author":"I Deary","year":"2010","journal-title":"Nature Reviews Neuroscience"},{"key":"ref83","unstructured":"Dehaene S (2002) The cognitive neuroscience of consciousness. MIT Press."},{"key":"ref84","doi-asserted-by":"crossref","first-page":"3366","DOI":"10.1093\/brain\/awp089","article-title":"Impaired small-world efficiency in structural cortical networks in multiple sclerosis associated with white matter lesion load","volume":"132","author":"Y He","year":"2009","journal-title":"Brain"},{"key":"ref85","doi-asserted-by":"crossref","first-page":"9477","DOI":"10.1523\/JNEUROSCI.0333-10.2010","article-title":"Functional connectivity and brain networks in schizophrenia","volume":"30","author":"M Lynall","year":"2010","journal-title":"The Journal of Neuroscience"},{"key":"ref86","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.euroneuro.2010.03.008","article-title":"Exploring the brain network: a review on resting-state fmri functional connectivity","volume":"20","author":"M van den Heuvel","year":"2010","journal-title":"European Neuropsychopharmacology"},{"key":"ref87","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1749-6632.2010.05888.x","article-title":"The human connectome: a complex network","volume":"1224","author":"O Sporns","year":"2011","journal-title":"Annals of the New York Academy of Sciences"},{"key":"ref88","doi-asserted-by":"crossref","first-page":"e1000748","DOI":"10.1371\/journal.pcbi.1000748","article-title":"Efficient physical embedding of topologically complex information processing networks in brains and computer circuits","volume":"6","author":"D Bassett","year":"2010","journal-title":"PLoS computational biology"},{"key":"ref89","doi-asserted-by":"crossref","first-page":"e17","DOI":"10.1371\/journal.pcbi.0030017","article-title":"Efficiency and cost of economical brain functional networks","volume":"3","author":"S Achard","year":"2007","journal-title":"PLoS computational biology"},{"key":"ref90","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1098\/rstb.1986.0056","article-title":"The structure of the nervous system of the nematode caenorhabditis elegans","volume":"314","author":"J White","year":"1986","journal-title":"Philosophical Transactions of the Royal Society of London B, Biological Sciences"},{"key":"ref91","unstructured":"Oshio K, Iwasaki Y, Morita S, Osana Y, Gomi S, <etal>et al<\/etal>.. Database of synaptic connectivity of c. elegans for computation. Technical report, Technical Report 3, CCeP, Keio Future, Keio University, Japan, 2003. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/ims.dse.ibaraki.ac.jp\/research\/databaseen.html\" xlink:type=\"simple\">http:\/\/ims.dse.ibaraki.ac.jp\/research\/databaseen.html<\/ext-link>."},{"key":"ref92","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1385\/NI:2:2:127","article-title":"Online retrieval, processing, and visualization of primate connectivity data from the cocomac database","volume":"2","author":"R K\u00f6tter","year":"2004","journal-title":"Neuroinformatics"},{"key":"ref93","unstructured":"Paxinos G, Huang X, Toga A (2008) The Rhesus Monkey Brain in Stereotaxic Coordinates. Academic Press."},{"key":"ref94","doi-asserted-by":"crossref","first-page":"3185","DOI":"10.1111\/j.1460-9568.2007.05574.x","article-title":"Simulation of robustness against lesions of cortical networks","volume":"25","author":"M Kaiser","year":"2007","journal-title":"European Journal of Neuroscience"},{"key":"ref95","doi-asserted-by":"crossref","first-page":"17757","DOI":"10.1073\/pnas.1010459107","article-title":"Regional aerobic glycolysis in the human brain","volume":"107","author":"S Vaishnavi","year":"2010","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"ref96","doi-asserted-by":"crossref","first-page":"16876","DOI":"10.1523\/JNEUROSCI.4136-10.2010","article-title":"Diffusion tensor tractography reveals abnormal topological organization in structural cortical networks in alzheimer&apos;s disease","volume":"30","author":"C Lo","year":"2010","journal-title":"The Journal of Neuroscience"},{"key":"ref97","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1523\/JNEUROSCI.05-04-00956.1985","article-title":"The neural circuit for touch sensitivity in caenorhabditis elegans","volume":"5","author":"M Chalfie","year":"1985","journal-title":"The Journal of neuroscience"},{"key":"ref98","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0896-6273(00)81168-X","article-title":"rpm-1, a conserved neuronal gene that regulates targeting and synaptogenesis in <italic>C. elegans<\/italic>","volume":"26","author":"A Schaefer","year":"2000","journal-title":"Neuron"},{"key":"ref99","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1146\/annurev.neuro.27.070203.144259","article-title":"Neuronal substrates of complex behaviors in c. elegans","volume":"28","author":"M Bono","year":"2005","journal-title":"Annu Rev Neurosci"},{"key":"ref100","doi-asserted-by":"crossref","first-page":"3184","DOI":"10.1073\/pnas.0409009101","article-title":"A circuit for navigation in caenorhabditis elegans","volume":"102","author":"J Gray","year":"2005","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref101","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/nmeth1075","article-title":"Microfluidics for in vivo imaging of neuronal and behavioral activity in caenorhabditis elegans","volume":"4","author":"N Chronis","year":"2007","journal-title":"Nature methods"},{"key":"ref102","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0896-6273(00)80021-5","article-title":"Neuroglia and pioneer neurons express unc-6 to provide global and local netrin cues for guiding migrations in c. elegans","volume":"16","author":"W Wadsworth","year":"1996","journal-title":"Neuron"},{"key":"ref103","doi-asserted-by":"crossref","first-page":"036103","DOI":"10.1103\/PhysRevE.69.036103","article-title":"Spatial growth of real-world networks","volume":"69","author":"M Kaiser","year":"2004","journal-title":"Physical Review E"},{"key":"ref104","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/cercor\/1.1.1","article-title":"Distributed hierarchical processing in the primate cerebral cortex","volume":"1","author":"D Felleman","year":"1991","journal-title":"Cerebral cortex"},{"key":"ref105","article-title":"A weighted and directed interareal connectivity matrix for macaque cerebral cortex","author":"N Markov","year":"2012","journal-title":"Cerebral Cortex"},{"key":"ref106","unstructured":"Press WH, Teukolsky SA, Vetterling WT, Flannery BP (2007) Numerical recipes. 3rd edition. Cambridge University Press Cambridge."},{"key":"ref107","doi-asserted-by":"crossref","first-page":"066133","DOI":"10.1103\/PhysRevE.69.066133","article-title":"Fast algorithm for detecting community structure in networks","volume":"69","author":"M Newman","year":"2004","journal-title":"Physical Review E"},{"key":"ref108","doi-asserted-by":"crossref","first-page":"118703","DOI":"10.1103\/PhysRevLett.100.118703","article-title":"Community structure in directed networks","volume":"100","author":"E Leicht","year":"2008","journal-title":"Physical Review Letters"},{"key":"ref109","doi-asserted-by":"crossref","first-page":"046106","DOI":"10.1103\/PhysRevE.81.046106","article-title":"Performance of modularity maximization in practical contexts","volume":"81","author":"B Good","year":"2010","journal-title":"Physical Review E"},{"key":"ref110","first-page":"12064358","article-title":"Robust detection of dynamic community structure in networks. Chaos: In press","author":"D Bassett","year":"2012","journal-title":"arXiv preprint arXiv"},{"key":"ref111","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1137\/070710111","article-title":"Power-law distributions in empirical data","volume":"51","author":"A Clauset","year":"2009","journal-title":"SIAM review"}],"container-title":["PLoS Computational Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pcbi.1002937","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T00:33:55Z","timestamp":1715042035000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pcbi.1002937"}},"subtitle":[],"editor":[{"given":"Olaf","family":"Sporns","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2013,3,7]]},"references-count":111,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2013,3,7]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pcbi.1002937","relation":{},"ISSN":["1553-7358"],"issn-type":[{"value":"1553-7358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,7]]}}}