{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T19:27:19Z","timestamp":1774812439886,"version":"3.50.1"},"reference-count":12,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2014,1,23]],"date-time":"2014-01-23T00:00:00Z","timestamp":1390435200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.ploscompbiol.org"],"crossmark-restriction":false},"short-container-title":["PLoS Comput Biol"],"DOI":"10.1371\/journal.pcbi.1003404","type":"journal-article","created":{"date-parts":[[2014,1,23]],"date-time":"2014-01-23T22:55:45Z","timestamp":1390517745000},"page":"e1003404","update-policy":"https:\/\/doi.org\/10.1371\/journal.pcbi.corrections_policy","source":"Crossref","is-referenced-by-count":13,"title":["Bioinformatics Projects Supporting Life-Sciences Learning in High Schools"],"prefix":"10.1371","volume":"10","author":[{"given":"Isabel","family":"Marques","sequence":"first","affiliation":[]},{"given":"Paulo","family":"Almeida","sequence":"additional","affiliation":[]},{"given":"Renato","family":"Alves","sequence":"additional","affiliation":[]},{"given":"Maria Jo\u00e3o","family":"Dias","sequence":"additional","affiliation":[]},{"given":"Ana","family":"Godinho","sequence":"additional","affiliation":[]},{"given":"Jos\u00e9 B.","family":"Pereira-Leal","sequence":"additional","affiliation":[]}],"member":"340","published-online":{"date-parts":[[2014,1,23]]},"reference":[{"key":"ref1","article-title":"Science Education Now: a renewed pedagogy for the future of Europe","author":"M Rocard","year":"2007","journal-title":"European Commission"},{"key":"ref2","unstructured":"Kang K (2012) Graduate Enrollment in Science and Engineering Grew Substantially in the Past Decade but Slowed in 2010. National Center for Science and Engineering Studies. Available: http:\/\/www.nsf.gov\/statistics\/infbrief\/nsf12317\/<\/ext-link>. Accessed 20 December 2013."},{"key":"ref3","unstructured":"Kearney C (2010) Efforts to Increase Students' Interest in Pursuing Mathematics, Science and Technology Studies and Careers. Wastiau P, Gras-Vel\u00e1zquez A, Gre\u010dnerov\u00e1 B, Baptista R, editors. Brussels: European Schoolnet. Available: http:\/\/cms.eun.org\/shared\/data\/pdf\/spice_kearney_mst_report_nov2010.pdf<\/ext-link>. Accessed 20 December 2013."},{"key":"ref4","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1002\/j.2168-9830.2006.tb00884.x","article-title":"Inductive teaching and learning methods: Definitions, comparisons, and research bases","volume":"95","author":"MJ Prince","year":"2006","journal-title":"J Eng Ed"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1002\/bmb.2004.494032040376","article-title":"Bioinformatics in undergraduate education: Practical examples","volume":"32","author":"JA Boyle","year":"2004","journal-title":"Biochem Mol Biol Educ"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1662\/0002-7685(2001)063[0643:BPTFDS]2.0.CO;2","article-title":"Building phylogenetic trees from DNA sequence data: Investigating polar bear & giant panda ancestry","volume":"63","author":"C Alexandra Maier","year":"2001","journal-title":"The American Biology Teacher"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1002\/bmb.2006.49403401030","article-title":"A web-based genetic polymorphism learning approach for high school students and science teachers","volume":"34","author":"E Amenkhienan","year":"2006","journal-title":"Biochem Mol Biol Educ"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1038\/embor.2008.25","article-title":"Hedgehogs, humans and high-school science. The benefits of involving high-school students in university research","volume":"9","author":"G Pavesi","year":"2008","journal-title":"EMBO Rep"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1187\/cbe.07-08-0061","article-title":"An Innovative Plant Genomics and Gene Annotation Program for High School, Community College, and University Faculty","volume":"7","author":"G Hacisalihoglu","year":"2008","journal-title":"CBE Life Sci Educ"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"e1002244","DOI":"10.1371\/journal.pcbi.1002244","article-title":"A first attempt to bring computational biology into advanced high school biology classrooms","volume":"7","author":"SR Gallagher","year":"2011","journal-title":"PLoS Comp Biol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1187\/cbe.07-05-0026","article-title":"Bioinformatics in high school biology curricula: a study of state science standards","volume":"7","author":"SH Wefer","year":"2008","journal-title":"CBE Life Sci Educ"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"e1002243","DOI":"10.1371\/journal.pcbi.1002243","article-title":"Ten simple rules for teaching bioinformatics at the high school level","volume":"7","author":"D Form","year":"2011","journal-title":"PLoS Comp Biol"}],"container-title":["PLoS Computational Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pcbi.1003404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T06:33:17Z","timestamp":1589005997000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pcbi.1003404"}},"subtitle":[],"editor":[{"given":"Fran","family":"Lewitter","sequence":"first","affiliation":[]}],"short-title":[],"issued":{"date-parts":[[2014,1,23]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2014,1,23]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pcbi.1003404","relation":{},"ISSN":["1553-7358"],"issn-type":[{"value":"1553-7358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,23]]}}}