{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T13:35:15Z","timestamp":1767706515047},"reference-count":51,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2014,4,10]],"date-time":"2014-04-10T00:00:00Z","timestamp":1397088000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.ploscompbiol.org"],"crossmark-restriction":false},"short-container-title":["PLoS Comput Biol"],"DOI":"10.1371\/journal.pcbi.1003523","type":"journal-article","created":{"date-parts":[[2014,4,10]],"date-time":"2014-04-10T16:50:52Z","timestamp":1397148652000},"page":"e1003523","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pcbi.corrections_policy","source":"Crossref","is-referenced-by-count":93,"title":["Optimal Schedules of Light Exposure for Rapidly Correcting Circadian Misalignment"],"prefix":"10.1371","volume":"10","author":[{"given":"Kirill","family":"Serkh","sequence":"first","affiliation":[]},{"given":"Daniel B.","family":"Forger","sequence":"additional","affiliation":[]}],"member":"340","published-online":{"date-parts":[[2014,4,10]]},"reference":[{"key":"ref1","unstructured":"(2012) U.S. Citizen Traffic to Overseas Regions, Canada &amp; Mexico 2012. ITA Office of Travel &amp; Tourism Industries."},{"key":"ref2","first-page":"3","article-title":"Nonstandard work schedules over the life course: a first look","author":"HB Presser","year":"2011","journal-title":"Monthly Labor Review"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s11910-009-0024-7","article-title":"Neurobehavioral, health, and safety consequences associated with shift work in safety-sensitive professions","volume":"9","author":"LK Barger","year":"2009","journal-title":"Current neurology and neuroscience reports"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1093\/occmed\/kqg048","article-title":"Health disorders of shift workers","volume":"53","author":"A Knutsson","year":"2003","journal-title":"Occupational Medicine"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/S0140-6736(01)06108-6","article-title":"Health in a 24-h society","volume":"358","author":"SMW Rajaratnam","year":"2001","journal-title":"The Lancet"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1126\/science.3726555","article-title":"Bright light resets the human circadian pacemaker independent of the timing of the sleep-wake cycle","volume":"233","author":"CA Czeisler","year":"1986","journal-title":"Science"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/350059a0","article-title":"Light-induced suppression of endogenous circadian amplitude in humans","volume":"350","author":"ME Jewett","year":"1991","journal-title":"Nature"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1034\/j.1600-079X.2002.01885.x","article-title":"The effects of prior light history on the suppression of melatonin by light in humans","volume":"33","author":"M H\u00e9bert","year":"2002","journal-title":"Journal of Pineal Research"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"e1000418","DOI":"10.1371\/journal.pcbi.1000418","article-title":"Taking the Lag out of Jet Lag Through Model-Based Schedule Design","volume":"5","author":"DA Dean","year":"2009","journal-title":"PLoS computational biology"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/350018a0","article-title":"Resetting the human clock","volume":"350","author":"AT Winfree","year":"1991","journal-title":"Nature"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"R1574","DOI":"10.1152\/ajpregu.2000.279.5.R1574","article-title":"Dynamic resetting of the human circadian pacemaker by intermittent bright light","volume":"279","author":"DW Rimmer","year":"2000","journal-title":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"E174","DOI":"10.1152\/ajpendo.00385.2003","article-title":"Efficacy of a single sequence of intermittent bright light pulses for delaying circadian phase in humans","volume":"287","author":"C Gronfier","year":"2004","journal-title":"American Journal of Physiology-Endocrinology and Metabolism"},{"key":"ref13","first-page":"566","article-title":"Scheduled exposure to daylight: a potential strategy to reduce \u201cjet lag\u201d following transmeridian flight","volume":"20","author":"S Daan","year":"1984","journal-title":"Psychopharmacology bulletin"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1177\/0748730402238238","article-title":"Circadian adaptation to night-shift work by judicious light and darkness exposure","volume":"17","author":"DB Boivin","year":"2002","journal-title":"Journal of Biological Rhythms"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/074873049701200103","article-title":"Conflicting bright light exposure during night shifts impedes circadian adaptation","volume":"12","author":"PJ Mitchell","year":"1997","journal-title":"Journal of biological rhythms"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1177\/074873049901400608","article-title":"Revised limit cycle oscillator model of human circadian pacemaker","volume":"14","author":"ME Jewett","year":"1999","journal-title":"Journal of Biological Rhythms"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1177\/074873099129000867","article-title":"A Simpler Model of the Human Circadian Pacemaker","volume":"14","author":"DB Forger","year":"1999","journal-title":"Journal of Biological Rhythms"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.1126\/science.284.5423.2177","article-title":"Stability, precision, and near-24-hour period of the human circadian pacemaker","volume":"284","author":"CA Czeisler","year":"1999","journal-title":"Science"},{"key":"ref19","first-page":"A15","article-title":"Comparison of Mathematical Model Predictions to Experimental Data of Fatigue and Performance","volume":"75","author":"HPA Van Dongen","year":"2004","journal-title":"Aviation, Space, and Environmental Medicine"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1177\/0748730407301376","article-title":"Developing mathematical models of neurobehavioral performance for the \u201cReal World\u201d","volume":"22","author":"DA Dean","year":"2007","journal-title":"Journal of Biological Rhythms"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1177\/074873049901400609","article-title":"Quantifying human circadian pacemaker response to brief, extended, and repeated light stimuli over the phototopic range","volume":"14","author":"RE Kronauer","year":"1999","journal-title":"Journal of biological rhythms"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Winfree AT (2001) The geometry of biological time: Springer Verlag.","DOI":"10.1007\/978-1-4757-3484-3"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1038\/msb.2012.62","article-title":"A mechanism for robust circadian timekeeping via stoichiometric balance","volume":"8","author":"JK Kim","year":"2012","journal-title":"Molecular systems biology"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"20130221","DOI":"10.1098\/rsif.2013.0221","article-title":"Genetic redundancy strengthens the circadian clock leading to a narrow entrainment range","volume":"10","author":"A Erzberger","year":"2013","journal-title":"Journal of The Royal Society Interface"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jtbi.2013.04.039","article-title":"Critical phase shifts slow down circadian clock recovery: Implications for jet lag","volume":"333","author":"J-C Leloup","year":"2013","journal-title":"Journal of theoretical biology"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1126\/science.288.5466.682","article-title":"Resetting Central and Peripheral Circadian Oscillators in Transgenic Rats","volume":"288","author":"S Yamazaki","year":"2000","journal-title":"Science"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"6141","DOI":"10.1523\/JNEUROSCI.23-14-06141.2003","article-title":"An Abrupt Shift in the Day\/Night Cycle Causes Desynchrony in the Mammalian Circadian Center","volume":"23","author":"M Nagano","year":"2003","journal-title":"The Journal of Neuroscience"},{"key":"ref28","first-page":"R704","article-title":"Phase shifting two coupled circadian pacemakers: implications for jet lag","volume":"249","author":"PH Gander","year":"1985","journal-title":"American Journal of Physiology"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"148","DOI":"10.3109\/07420529209064526","article-title":"A mathematical model of the human circadian system and its application to jet lag","volume":"9","author":"A Gundel","year":"1992","journal-title":"Chronobiology International"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"e1000104","DOI":"10.1371\/journal.pcbi.1000104","article-title":"Circadian phase resetting via single and multiple control targets","volume":"4","author":"N Bagheri","year":"2008","journal-title":"PLoS computational biology"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"3007","DOI":"10.1109\/CDC.2012.6426226","article-title":"Optimal circadian rhythm control with light input for rapid entrainment and improved vigilance","author":"J Zhang","year":"2012","journal-title":"Decision and Control (CDC), 2012 IEEE 51st Annual Conference on"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1093\/sleep\/30.9.1129","article-title":"Optimization of biomathematical model predictions for cognitive performance impairment in individuals: accounting for unknown traits and uncertain states in homeostatic and circadian processes","volume":"30","author":"HPA Van Dongen","year":"2007","journal-title":"Sleep"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"6058","DOI":"10.1109\/CDC.2010.5718105","article-title":"Circadian system modeling and phase control","author":"J Zhang","year":"2010","journal-title":"Decision and Control (CDC), 2010 49th IEEE Conference on"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.jtbi.2004.04.043","article-title":"Starting, stopping, and resetting biological oscillators: in search of optimum perturbations","volume":"230","author":"DB Forger","year":"2004","journal-title":"Journal of theoretical biology"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"88301","DOI":"10.1103\/PhysRevLett.105.088301","article-title":"Optimal waveform for the entrainment of a weakly forced oscillator","volume":"105","author":"T Harada","year":"2010","journal-title":"Physical review letters"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1177\/074873049400900310","article-title":"Phase-amplitude resetting of the human circadian pacemaker via bright light: a further analysis","volume":"9","author":"ME Jewett","year":"1994","journal-title":"Journal of biological rhythms"},{"key":"ref37","unstructured":"Winfree AT (1987) Timing of Biological Clocks. W H Freeman &amp; Co."},{"key":"ref38","doi-asserted-by":"crossref","first-page":"147","DOI":"10.3109\/07420528909064625","article-title":"Transition between advance and delay responses to eastbound transmeridian flights","volume":"6","author":"A Gundel","year":"1989","journal-title":"Chronobiology international"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"e30037","DOI":"10.1371\/journal.pone.0030037","article-title":"Amplitude Reduction and Phase Shifts of Melatonin, Cortisol and Other Circadian Rhythms after a Gradual Advance of Sleep and Light Exposure in Humans","volume":"7","author":"DJ Dijk","year":"2012","journal-title":"PloS one"},{"key":"ref40","first-page":"1","article-title":"Validating the Use of Wrist-Level Light Monitoring for In-Hospital Circadian Studies","author":"ACN Jardim","year":"2011","journal-title":"Chronobiology International"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1046\/j.1440-1819.2001.00857.x","article-title":"Re-entrainment of the circadian rhythms of plasma melatonin in an 11-h eastward bound flight","volume":"55","author":"T Takahashi","year":"2001","journal-title":"Psychiatry and clinical neurosciences"},{"key":"ref42","unstructured":"Izhikevich EM (2010) Dynamical Systems in Neuroscience: The Geometry of Excitability and Bursting (Computational Neuroscience): The MIT Press."},{"key":"ref43","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1080\/07420520500180371","article-title":"Comparison of amplitude recovery dynamics of two limit cycle oscillator models of the human circadian pacemaker","volume":"22","author":"P Indic","year":"2005","journal-title":"Chronobiology international"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1177\/0748730405277233","article-title":"How to trick mother nature into letting you fly around or stay up all night","volume":"20","author":"VL Revell","year":"2005","journal-title":"Journal of biological rhythms"},{"key":"ref45","first-page":"953","article-title":"Light visor treatment for jet lag after westward travel across six time zones","volume":"73","author":"Z Boulos","year":"2002","journal-title":"Aviation, space, and environmental medicine"},{"key":"ref46","first-page":"722","article-title":"Type 0 resetting of the human circadian pacemaker to consecutive bright light pulses against a background of very dim light","volume":"26","author":"S Khalsa","year":"1997","journal-title":"Sleep Res"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"14806","DOI":"10.1073\/pnas.2036281100","article-title":"A detailed predictive model of the mammalian circadian clock","volume":"100","author":"DB Forger","year":"2003","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"859","DOI":"10.2514\/3.25412","article-title":"Efficient algorithm for time-optimal control of a two-link manipulator","volume":"13","author":"EB Meier","year":"1990","journal-title":"Journal of Guidance, Control, and Dynamics"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1056\/NEJMcp0909838","article-title":"Jet lag","volume":"362","author":"RL Sack","year":"2010","journal-title":"New England Journal of Medicine"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1016\/S0140-6736(97)07569-7","article-title":"Jet-lag","volume":"350","author":"J Waterhouse","year":"1997","journal-title":"The Lancet"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.jsmc.2009.02.006","article-title":"How to travel the world without jet lag","volume":"4","author":"CI Eastman","year":"2009","journal-title":"Sleep medicine clinics"}],"container-title":["PLoS Computational Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pcbi.1003523","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,9]],"date-time":"2019-08-09T07:50:47Z","timestamp":1565337047000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pcbi.1003523"}},"subtitle":[],"editor":[{"given":"Olaf","family":"Sporns","sequence":"first","affiliation":[]}],"short-title":[],"issued":{"date-parts":[[2014,4,10]]},"references-count":51,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2014,4,10]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pcbi.1003523","relation":{},"ISSN":["1553-7358"],"issn-type":[{"value":"1553-7358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,10]]}}}