{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T14:53:14Z","timestamp":1774363994277,"version":"3.50.1"},"update-to":[{"DOI":"10.1371\/journal.pcbi.1006009","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2018,3,14]],"date-time":"2018-03-14T00:00:00Z","timestamp":1520985600000}}],"reference-count":86,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2018,3,2]],"date-time":"2018-03-02T00:00:00Z","timestamp":1519948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.ploscompbiol.org"],"crossmark-restriction":false},"short-container-title":["PLoS Comput Biol"],"DOI":"10.1371\/journal.pcbi.1006009","type":"journal-article","created":{"date-parts":[[2018,3,2]],"date-time":"2018-03-02T18:23:41Z","timestamp":1520015021000},"page":"e1006009","update-policy":"https:\/\/doi.org\/10.1371\/journal.pcbi.corrections_policy","source":"Crossref","is-referenced-by-count":21,"title":["Classifying dynamic transitions in high dimensional neural mass models: A random forest approach"],"prefix":"10.1371","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3166-9685","authenticated-orcid":true,"given":"Lauric A.","family":"Ferrat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Goodfellow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John R.","family":"Terry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2018,3,2]]},"reference":[{"issue":"1","key":"ref1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/BF00270757","article-title":"Model of brain rhythmic activity\u2014The alpha-rhythm of the thalamus","volume":"15","author":"FH Lopes da Silva","year":"1974","journal-title":"Kybernetik"},{"issue":"9","key":"ref2","doi-asserted-by":"crossref","first-page":"e1004352","DOI":"10.1371\/journal.pcbi.1004352","article-title":"Relating Alpha Power and Phase to Population Firing and Hemodynamic Activity Using a Thalamo-cortical Neural Mass Model","volume":"11","author":"R Becker","year":"2015","journal-title":"PLoS computational biology"},{"issue":"1","key":"ref3","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/s10827-013-0493-1","article-title":"A thalamo-cortical neural mass model for the simulation of brain rhythms during sleep","volume":"37","author":"F Cona","year":"2014","journal-title":"Journal of Computational Neuroscience"},{"issue":"9","key":"ref4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pcbi.1005022","article-title":"A Thalamocortical Neural Mass Model of the EEG during NREM Sleep and Its Response to Auditory Stimulation","volume":"12","author":"M Schellenberger Costa","year":"2016","journal-title":"PLoS Computational Biology"},{"issue":"11","key":"ref5","doi-asserted-by":"crossref","first-page":"e1003923","DOI":"10.1371\/journal.pcbi.1003923","article-title":"Characterization of K-Complexes and Slow Wave Activity in a Neural Mass Model","volume":"10","author":"A Weigenand","year":"2014","journal-title":"PLoS Computational Biology"},{"key":"ref6","article-title":"Dynamics of biologically informed neural mass models of the brain","author":"A Spiegler","year":"2011"},{"issue":"3","key":"ref7","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/j.neuroimage.2010.12.074","article-title":"Intermittent spike-wave dynamics in a heterogeneous, spatially extended neural mass model","volume":"55","author":"M Goodfellow","year":"2011","journal-title":"NeuroImage"},{"issue":"3","key":"ref8","doi-asserted-by":"crossref","first-page":"2644","DOI":"10.1016\/j.neuroimage.2011.08.060","article-title":"Self-organised transients in a neural mass model of epileptogenic tissue dynamics","volume":"59","author":"M Goodfellow","year":"2012","journal-title":"NeuroImage"},{"issue":"0","key":"ref9","doi-asserted-by":"crossref","first-page":"29215","DOI":"10.1038\/srep29215","article-title":"Estimation of brain network ictogenicity predicts outcome from epilepsy surgery","volume":"6","author":"M Goodfellow","year":"2016","journal-title":"Scientific reports"},{"key":"ref10","first-page":"1","article-title":"Computational models of epileptiform activity","author":"F Wendling","year":"2015","journal-title":"Journal of Neuroscience Methods"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1046\/j.1460-9568.2002.01985.x","article-title":"Epileptic fast activity can be explained by a model of impaired GABAergic dendritic inhibition","volume":"15","author":"F Wendling","year":"2002","journal-title":"European Journal of Neuroscience"},{"issue":"1-3","key":"ref12","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.schres.2014.06.011","article-title":"The functional anatomy of schizophrenia: A dynamic causal modeling study of predictive coding","volume":"158","author":"N Fogelson","year":"2014","journal-title":"Schizophrenia Research"},{"issue":"6","key":"ref13","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.neunet.2011.02.009","article-title":"A thalamo-cortico-thalamic neural mass model to study alpha rhythms in Alzheimer\u2019s disease","volume":"24","author":"BS Bhattacharya","year":"2011","journal-title":"Neural Networks"},{"issue":"4","key":"ref14","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1097\/WCO.0000000000000344","article-title":"A new neuroinformatics approach to personalized medicine in neurology","volume":"29","author":"MI Falcon","year":"2016","journal-title":"Current Opinion in Neurology"},{"issue":"November","key":"ref15","first-page":"1","article-title":"Estimation of Effective Connectivity via Data-Driven Neural Modeling","volume":"8","author":"DR Freestone","year":"2014","journal-title":"Estimation of Effective Connectivity via Data-Driven Neural Modeling"},{"issue":"2","key":"ref16","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1162\/NECO_a_00925","article-title":"Controllability Analysis of the Neural Mass Model with Dynamic Parameters","volume":"29","author":"X Liu","year":"2017","journal-title":"Neural Computation"},{"issue":"May","key":"ref17","first-page":"57","article-title":"Neural masses and fields in dynamic causal modeling","volume":"7","author":"R Moran","year":"2013","journal-title":"Frontiers in computational neuroscience"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/B978-012372560-8\/50042-5","article-title":"Dynamic causal models for EEG","author":"K Friston","year":"2007","journal-title":"Statistical Parametric Mapping: The Analysis of Functional Brain Images"},{"issue":"4","key":"ref19","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/BF00199471","article-title":"Electroencephalogram and visual evoked potential generation in a mathematical model of coupled cortical columns","volume":"73","author":"BH Jansen","year":"1995","journal-title":"Biological Cybernetics"},{"issue":"2","key":"ref20","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/BF02463252","article-title":"A model of the spatial-temporal characteristics of the alpha rhythm","volume":"44","author":"A van Rotterdam","year":"1982","journal-title":"Bulletin of Mathematical Biology"},{"issue":"2-3","key":"ref21","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/BF00317988","article-title":"Simulation of chaotic EEG patterns with a dynamic model of the olfactory system","volume":"56","author":"WJ Freeman","year":"1987","journal-title":"Biological Cybernetics"},{"issue":"C","key":"ref22","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0079-6123(08)60995-4","article-title":"Models of Neuronal Populations: The Basic Mechanisms of Rhythmicity","volume":"45","author":"FH Lopes da Silva","year":"1976","journal-title":"Progress in Brain Research"},{"issue":"5","key":"ref23","first-page":"423","article-title":"Mass action in the nervous system","volume":"1","author":"WJ Freeman","year":"1975","journal-title":"Neuroscience"},{"issue":"4","key":"ref24","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/BF00344205","article-title":"EEG analysis gives model of neuronal template-matching mechanism for sensory search with olfactory bulb","volume":"35","author":"WJ Freeman","year":"1979","journal-title":"Biological Cybernetics"},{"issue":"1","key":"ref25","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/BF01845841","article-title":"Nonlinear dynamics of paleocortex manifested in the olfactory EEG","volume":"35","author":"WJ Freeman","year":"1979","journal-title":"Biological Cybernetics"},{"issue":"4","key":"ref26","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/BF00337412","article-title":"Nonlinear gain mediating cortical stimulus-response relations","volume":"33","author":"WJ Freeman","year":"1979","journal-title":"Biological Cybernetics"},{"issue":"669","key":"ref27","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1098\/rstb.1956.0012","article-title":"Properties of a Mass of Cells Capable of Regenerating Pulses","volume":"240","author":"RL Beurle","year":"1956","journal-title":"Philosophical Transactions of the Royal Society B: Biological Sciences"},{"issue":"8","key":"ref28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1000092","article-title":"The dynamic brain: From spiking neurons to neural masses and cortical fields","volume":"4","author":"G Deco","year":"2008","journal-title":"PLoS Computational Biology"},{"issue":"April","key":"ref29","first-page":"40","article-title":"NeuroElectro: a window to the world\u2019s neuron electrophysiology data","volume":"8","author":"SJ Tripathy","year":"2014","journal-title":"Frontiers in neuroinformatics"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"3232","DOI":"10.1162\/NECO_a_00206","article-title":"Neural Mass Activity, Bifurcations, and Epilepsy","volume":"23","author":"J Touboul","year":"2011","journal-title":"Neural Computation"},{"key":"ref31","first-page":"63","article-title":"Recent Advances in Predicting and Preventing Epileptic Seizures","author":"DR Freestone","year":"2013"},{"issue":"3","key":"ref32","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1016\/j.neuroimage.2011.08.111","article-title":"Characterising the dynamics of EEG waveforms as the path through parameter space of a neural mass model: Application to epilepsy seizure evolution","volume":"59","author":"AJ Nevado-Holgado","year":"2012","journal-title":"NeuroImage"},{"issue":"2","key":"ref33","doi-asserted-by":"crossref","first-page":"2188","DOI":"10.1111\/j.1460-9568.2012.08082.x","article-title":"The dynamic evolution of focal-onset epilepsies\u2014combining theoretical and clinical observations","volume":"36","author":"A Blenkinsop","year":"2012","journal-title":"European Journal of Neuroscience"},{"key":"ref34","unstructured":"Hebbink J. Activity types in a neural mass model. University of Twente; 2014. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.utwente.nl\/en\/eemcs\/sacs\/teaching\/Thesis\/hebbink-jurgen-activity-types-in-a-neural-mass-model-fp-report-final.pdf\" xlink:type=\"simple\">https:\/\/www.utwente.nl\/en\/eemcs\/sacs\/teaching\/Thesis\/hebbink-jurgen-activity-types-in-a-neural-mass-model-fp-report-final.pdf<\/ext-link>."},{"issue":"3","key":"ref35","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/j.neuroimage.2009.12.081","article-title":"Bifurcation analysis of neural mass models: Impact of extrinsic inputs and dendritic time constants","volume":"52","author":"A Spiegler","year":"2010","journal-title":"NeuroImage"},{"issue":"1","key":"ref36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0951-8320(96)00002-6","article-title":"Importance measures in global sensitivity analysis of nonlinear models","volume":"52","author":"T Homma","year":"1996","journal-title":"Reliability Engineering & System Safety"},{"issue":"10","key":"ref37","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1016\/j.envsoft.2006.10.004","article-title":"An effective screening design for sensitivity analysis of large models","volume":"22","author":"F Campolongo","year":"2007","journal-title":"Environmental Modelling & Software"},{"issue":"5941","key":"ref38","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1126\/science.1173536","article-title":"Generalized Models Reveal Stabilizing Factors in Food Webs","volume":"325","author":"T Gross","year":"2009","journal-title":"Science"},{"key":"ref39","article-title":"vol. 1 of Springer Series in Statistics","author":"T Hastie","year":"2009"},{"issue":"2","key":"ref40","first-page":"239","article-title":"Comparison of Three Methods for Selecting Values of Input Variables in the Analysis of Output from a Computer Code","volume":"21","author":"MD McKay","year":"1979","journal-title":"Technometrics"},{"issue":"4","key":"ref41","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s004220000160","article-title":"Relevance of nonlinear lumped-parameter models in the analysis of depth-EEG epileptic signals","volume":"83","author":"F Wendling","year":"2000","journal-title":"Biological cybernetics"},{"issue":"3","key":"ref42","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1113\/jphysiol.2006.105379","article-title":"Contributions of principal neocortical neurons to magnetoencephalography and electroencephalography signals","volume":"575","author":"S Murakami","year":"2006","journal-title":"The Journal of Physiology"},{"issue":"3","key":"ref43","first-page":"1","article-title":"Influence of extrinsic inputs and synaptic gains on dynamics of Wendling\u2019s neural mass model: A bifurcation analysis","volume":"15","author":"S Geng","year":"2017","journal-title":"Journal of Integrative Neuroscience"},{"issue":"5","key":"ref44","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1152\/jn.1993.70.5.2066","article-title":"Signal delay and input synchronization in passive dendritic structures","volume":"70","author":"H Agmon-Snir","year":"1993","journal-title":"Journal of neurophysiology"},{"issue":"1","key":"ref45","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/neu.20144","article-title":"Synaptic integration in dendritic trees","volume":"64","author":"AT Gulledge","year":"2005","journal-title":"Journal of Neurobiology"},{"issue":"2","key":"ref46","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1113\/jphysiol.2007.143065","article-title":"Transition to seizures in the isolated immature mouse hippocampus: a switch from dominant phasic inhibition to dominant phasic excitation","volume":"586","author":"M Derchansky","year":"2008","journal-title":"The Journal of physiology"},{"issue":"2","key":"ref47","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S0306-4522(02)00874-6","article-title":"Increased spike broadening and slow afterhyperpolarization in CA1 pyramidal cells of streptozotocin-induced diabetic rats","volume":"118","author":"A Kamal","year":"2003","journal-title":"Neuroscience"},{"issue":"12","key":"ref48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0015915","article-title":"Molecular and electrophysiological characterization of GFP-expressing ca1 interneurons in GAD65-GFP mice","volume":"5","author":"CJ Wierenga","year":"2010","journal-title":"PLoS ONE"},{"issue":"2","key":"ref49","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0896-6273(93)90310-N","article-title":"Physiological evidence for two distinct GABAA responses in rat hippocampus","volume":"10","author":"RA Pearce","year":"1993","journal-title":"Neuron"},{"issue":"6","key":"ref50","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1093\/cercor\/7.6.510","article-title":"Synaptic interactions in neocortical local circuits: dual intracellular recordings in vitro","volume":"7","author":"A Thomson","year":"1997","journal-title":"Cerebral Cortex"},{"issue":"2","key":"ref51","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.neuroscience.2004.03.014","article-title":"Dynamics of non-convulsive epileptic phenomena modeled by a bistable neuronal network","volume":"126","author":"P Suffczynski","year":"2004","journal-title":"Neuroscience"},{"issue":"July 2016","key":"ref52","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.neuroimage.2016.11.034","article-title":"Temporally correlated fluctuations drive epileptiform dynamics","volume":"146","author":"M Jedynak","year":"2017","journal-title":"NeuroImage"},{"key":"ref53","article-title":"Classification and Regression Trees","author":"L Breiman","year":"1984"},{"issue":"1","key":"ref54","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0020-0190(76)90095-8","article-title":"Constructing optimal binary decision trees is NP-complete","volume":"5","author":"L Hyafil","year":"1976","journal-title":"Information Processing Letters"},{"key":"ref55","unstructured":"Breiman L. Consistency for a simple model of random forests. University of California at Berkeley. Technical Report 670; 2004."},{"issue":"1","key":"ref56","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1023\/A:1010933404324","article-title":"Random forest","volume":"45","author":"L Breiman","year":"2001","journal-title":"Machine Learning"},{"key":"ref57","unstructured":"Breiman L. Some infinity theory for predictor ensembles. University of California at Berkeley. Technical Report 577 (August 2000); 2000. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.stat.berkeley.edu\/{~}breiman\/\" xlink:type=\"simple\">https:\/\/www.stat.berkeley.edu\/{~}breiman\/<\/ext-link>."},{"key":"ref58","unstructured":"Caruana R, Niculescu-Mizil A. An empirical comparison of supervised learning algorithms. In: Proceedings of the 23rd international conference on Machine learning\u2014ICML\u201906. New York, New York, USA: ACM Press; 2006. p. 161\u2013168. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/portal.acm.org\/citation.cfm?doid=1143844.1143865\" xlink:type=\"simple\">http:\/\/portal.acm.org\/citation.cfm?doid=1143844.1143865<\/ext-link>."},{"key":"ref59","first-page":"3133","article-title":"Do we Need Hundreds of Classifiers to Solve Real World Classification Problems?","volume":"15","author":"M Fern\u00e1ndez-Delgado","year":"2014","journal-title":"Journal of Machine Learning Research"},{"issue":"421","key":"ref60","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/BF00058655","article-title":"Bagging Predictors","volume":"24","author":"L Breiman","year":"1996","journal-title":"Machine Learning"},{"issue":"1","key":"ref61","doi-asserted-by":"crossref","first-page":"32","DOI":"10.2202\/1544-6115.1691","article-title":"Random Forests for Genetic Association Studies","volume":"10","author":"BA Goldstein","year":"2011","journal-title":"Statistical Applications in Genetics and Molecular Biology"},{"key":"ref62","first-page":"409","article-title":"R: A Language and Environment for Statistical Computing","volume":"1","year":"2017"},{"issue":"5","key":"ref63","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1177\/154405910408300516","article-title":"Indian Hedgehog: A Mechanotransduction Mediator in Condylar Cartilage","volume":"83","author":"GH Tang","year":"2004","journal-title":"Journal of Dental Research"},{"key":"ref64","doi-asserted-by":"crossref","unstructured":"Therneau T, Atkinson B, Ripley B. rpart: Recursive Partitioning and Regression Trees. R package version 4.1-11.; 2017. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/cran.r-project.org\/web\/packages\/rpart\" xlink:type=\"simple\">https:\/\/cran.r-project.org\/web\/packages\/rpart<\/ext-link>.","DOI":"10.32614\/CRAN.package.rpart"},{"key":"ref65","unstructured":"Milborrow S. rpart.plot: Plot\u2019rpart\u2019 Models: An Enhanced Version of\u2019plot.rpart\u2019 version 2.1.2; 2017. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/cran.r-project.org\/package=rpart.plot\" xlink:type=\"simple\">https:\/\/cran.r-project.org\/package=rpart.plot<\/ext-link>."},{"key":"ref66","unstructured":"Goodfellow I, Bengio Y, Courville A. Deep Learning. In: Deep Learning; 2016. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.deeplearningbook.org\" xlink:type=\"simple\">http:\/\/www.deeplearningbook.org<\/ext-link>."},{"issue":"3","key":"ref67","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/BF00994018","article-title":"Support-vector networks","volume":"20","author":"C Cortes","year":"1995","journal-title":"Machine Learning"},{"issue":"3","key":"ref68","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1111\/j.1467-9868.2004.05304.x","article-title":"Probabilistic sensitivity analysis of complex models: A Bayesian approach","volume":"66","author":"JE Oakley","year":"2004","journal-title":"Journal of the Royal Statistical Society Series B: Statistical Methodology"},{"issue":"1-2","key":"ref69","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.ymssp.2012.05.010","article-title":"Bayesian sensitivity analysis of bifurcating nonlinear models","volume":"34","author":"W Becker","year":"2013","journal-title":"Mechanical Systems and Signal Processing"},{"issue":"October","key":"ref70","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1198\/016214508000000689","article-title":"Bayesian Treed Gaussian Process Models with an Application to Computer Modeling","volume":"103","author":"R Gramacy","year":"2008","journal-title":"Journal of the American Statistical Asociation"},{"issue":"4","key":"ref71","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/S0034-4257(03)00132-9","article-title":"An assessment of the effectiveness of decision tree methods for land cover classification","volume":"86","author":"M Pal","year":"2003","journal-title":"Remote Sensing of Environment"},{"issue":"1","key":"ref72","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10115-007-0114-2","article-title":"Top 10 algorithms in data mining","volume":"14","author":"X Wu","year":"2008","journal-title":"Knowledge and Information Systems"},{"issue":"July","key":"ref73","first-page":"1","article-title":"The importance of modeling epileptic seizure dynamics as spatio-temporal patterns","volume":"3","author":"G Baier","year":"2012","journal-title":"Frontiers in Physiology"},{"issue":"1","key":"ref74","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1093\/bib\/bbq011","article-title":"Letter to the Editor: Stability of Random Forest importance measures","volume":"12","author":"ML Calle","year":"2011","journal-title":"Briefings in Bioinformatics"},{"issue":"3","key":"ref75","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1002\/jmri.24611","article-title":"Investigation of glutamine and GABA levels in patients with idiopathic generalized epilepsy using MEGAPRESS","volume":"41","author":"FA Chowdhury","year":"2015","journal-title":"Journal of Magnetic Resonance Imaging"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"g254","DOI":"10.1136\/bmj.g254","article-title":"Drug treatment of epilepsy in adults","volume":"348","author":"D Schmidt","year":"2014","journal-title":"The BMJ"},{"issue":"6","key":"ref77","doi-asserted-by":"crossref","first-page":"3229","DOI":"10.1152\/jn.01128.2015","article-title":"Specific imbalance of excitatory\/inhibitory signaling establishes seizure onset pattern in temporal lobe epilepsy","volume":"115","author":"M Avoli","year":"2016","journal-title":"Journal of Neurophysiology"},{"issue":"3","key":"ref78","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1016\/j.neuroimage.2003.07.015","article-title":"A neural mass model for MEG\/EEG: Coupling and neuronal dynamics","volume":"20","author":"O David","year":"2003","journal-title":"NeuroImage"},{"issue":"1","key":"ref79","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.neuroimage.2008.04.239","article-title":"Population dynamics: Variance and the sigmoid activation function","volume":"42","author":"AC Marreiros","year":"2008","journal-title":"NeuroImage"},{"issue":"37","key":"ref80","doi-asserted-by":"crossref","first-page":"9866","DOI":"10.1523\/JNEUROSCI.2761-07.2007","article-title":"Perturbed Chloride Homeostasis and GABAergic Signaling in Human Temporal Lobe Epilepsy","volume":"27","author":"G Huberfeld","year":"2007","journal-title":"Journal of Neuroscience"},{"issue":"33","key":"ref81","doi-asserted-by":"crossref","first-page":"10416","DOI":"10.1523\/JNEUROSCI.1670-09.2009","article-title":"Intracellular Chloride Ions Regulate the Time Course of GABA-Mediated Inhibitory Synaptic Transmission","volume":"29","author":"CM Houston","year":"2009","journal-title":"Journal of Neuroscience"},{"key":"ref82","doi-asserted-by":"crossref","unstructured":"Rosch RE, Hunter P, Baldeweg T, Friston K, Meyer M. Imaging and dynamic causal modelling reveal brain-wide changes in effective connectivity and synaptic dynamics during epileptic seizures. bioRxiv. 2017;","DOI":"10.1101\/160259"},{"key":"ref83","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4020-6356-5","article-title":"Numerical Continuation Methods for Dynamical Systems","author":"B Krauskopf","year":"2007"},{"issue":"s12","key":"ref84","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/j.0013-9580.2003.12005.x","article-title":"Epilepsies as Dynamical Diseases of Brain Systems: Basic Models of the Transition Between Normal and Epileptic Activity","volume":"44","author":"FL da Silva","year":"2003","journal-title":"Epilepsia"},{"issue":"1","key":"ref85","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/hbm.20032","article-title":"Estimation of multiscale neurophysiologic parameters by electroencephalographic means","volume":"23","author":"PA Robinson","year":"2004","journal-title":"Human Brain Mapping"},{"key":"ref86","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1016\/j.neuroimage.2006.02.034","article-title":"Mechanisms of evoked and induced responses in MEG\/EEG","volume":"31","author":"O David","year":"2006","journal-title":"NeuroImage"}],"updated-by":[{"DOI":"10.1371\/journal.pcbi.1006009","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2018,3,14]],"date-time":"2018-03-14T00:00:00Z","timestamp":1520985600000}}],"container-title":["PLOS Computational Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pcbi.1006009","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T18:33:15Z","timestamp":1719858795000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pcbi.1006009"}},"subtitle":[],"editor":[{"given":"Levin","family":"Kuhlmann","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2018,3,2]]},"references-count":86,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,3,2]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pcbi.1006009","relation":{"new_version":[{"id-type":"doi","id":"10.1371\/journal.pcbi.1006009","asserted-by":"object"}]},"ISSN":["1553-7358"],"issn-type":[{"value":"1553-7358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,2]]}}}