{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T01:42:47Z","timestamp":1788054167727,"version":"build-2784847793"},"update-to":[{"DOI":"10.1371\/journal.pcbi.1008065","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2020,8,26]],"date-time":"2020-08-26T00:00:00Z","timestamp":1598400000000}}],"reference-count":26,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2020,8,14]],"date-time":"2020-08-14T00:00:00Z","timestamp":1597363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["IIS-1526415"],"award-info":[{"award-number":["IIS-1526415"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["CCF-1718093"],"award-info":[{"award-number":["CCF-1718093"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["IIS-1909425"],"award-info":[{"award-number":["IIS-1909425"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.ploscompbiol.org"],"crossmark-restriction":false},"short-container-title":["PLoS Comput Biol"],"DOI":"10.1371\/journal.pcbi.1008065","type":"journal-article","created":{"date-parts":[[2020,8,14]],"date-time":"2020-08-14T15:18:12Z","timestamp":1597418292000},"page":"e1008065","update-policy":"https:\/\/doi.org\/10.1371\/journal.pcbi.corrections_policy","source":"Crossref","is-referenced-by-count":11,"title":["Inferring the ancestry of parents and grandparents from genetic data"],"prefix":"10.1371","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7657-0144","authenticated-orcid":true,"given":"Jingwen","family":"Pei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9735-0418","authenticated-orcid":true,"given":"Yiming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0513-6591","authenticated-orcid":true,"given":"Rasmus","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4988-3521","authenticated-orcid":true,"given":"Yufeng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,8,14]]},"reference":[{"key":"pcbi.1008065.ref001","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1159\/000121396","article-title":"Genetics and Identity","volume":"11","author":"A Nordgren","year":"2008","journal-title":"Community Genet"},{"key":"pcbi.1008065.ref002","doi-asserted-by":"crossref","first-page":"2381","DOI":"10.1126\/science.1078311","article-title":"Genetic structure of human populations","volume":"298","author":"NA Rosenberg","year":"2002","journal-title":"Science"},{"key":"pcbi.1008065.ref003","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1126\/science.1153717","article-title":"Worldwide human relationships inferred from genome-wide patterns of variation","volume":"319","author":"J Li","year":"2008","journal-title":"Science"},{"key":"pcbi.1008065.ref004","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1093\/genetics\/155.2.945","article-title":"Inference of Population Structure Using Multilocus Genotype Data","volume":"155","author":"JP Pritchard","year":"2000","journal-title":"Genetics"},{"key":"pcbi.1008065.ref005","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/gepi.20064","article-title":"Estimation of individual admixture: analytical and study design considerations","volume":"28","author":"H Tang","year":"2005","journal-title":"Genetic epidemiology"},{"key":"pcbi.1008065.ref006","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1101\/gr.094052.109","article-title":"Fast model-based estimation of ancestry in unrelated individuals","volume":"19","author":"D Alexander","year":"2009","journal-title":"Genome research"},{"key":"pcbi.1008065.ref007","doi-asserted-by":"crossref","first-page":"i190","DOI":"10.1093\/bioinformatics\/btv239","article-title":"Inferring parental genomic ancestries using pooled semi-Markov processes","volume":"31","author":"JY Zou","year":"2015","journal-title":"Bioinformatics"},{"key":"pcbi.1008065.ref008","first-page":"607","article-title":"Population genetics models of local ancestry","volume":"191","author":"S Gravel","year":"2012","journal-title":"Genome research"},{"key":"pcbi.1008065.ref009","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1038\/nature15393","article-title":"A global reference for human genetic variation","volume":"526","author":"The 1000 Genomes Project Consortium","year":"2015","journal-title":"Nature"},{"key":"pcbi.1008065.ref010","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1534\/genetics.114.162362","article-title":"The Lengths of Admixture Tracts","volume":"197","author":"M Liang","year":"2014","journal-title":"Genetics"},{"key":"pcbi.1008065.ref011","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1086\/504302","article-title":"Reconstructing Genetic Ancestry Blocks in Admixed Individuals","volume":"79","author":"H Tang","year":"2006","journal-title":"American Journal of Human Genetics"},{"key":"pcbi.1008065.ref012","doi-asserted-by":"crossref","first-page":"e1000519","DOI":"10.1371\/journal.pgen.1000519","article-title":"Sensitive Detection of Chromosomal Segments of Distinct Ancestry in Admixed Populations","volume":"5","author":"A Price","year":"2009","journal-title":"PLoS Genetics"},{"key":"pcbi.1008065.ref013","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.ajhg.2007.09.022","article-title":"Estimating local ancestry in admixed populations","volume":"82","author":"S Sankararaman","year":"2008","journal-title":"American Journal of Human Genetics"},{"key":"pcbi.1008065.ref014","doi-asserted-by":"crossref","first-page":"i213","DOI":"10.1093\/bioinformatics\/btp197","article-title":"Inference of locus-specific ancestry in closely related populations","volume":"25","author":"B Pa\u015faniuc","year":"2009","journal-title":"Bioinformatics"},{"key":"pcbi.1008065.ref015","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1073\/pnas.84.8.2363","article-title":"Construction of multilocus genetic linkage maps in humans","volume":"84","author":"ES Lander","year":"1987","journal-title":"Proc of the Nat Academy of Science"},{"key":"pcbi.1008065.ref016","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1159\/000154413","article-title":"A faster and more general hidden Markov model algorithm for multipoint likelihood calculations","volume":"47","author":"R Idury","year":"1997","journal-title":"Hum Hered"},{"key":"pcbi.1008065.ref017","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1007\/BF01589116","article-title":"On the limited memory BFGS method for large scale optimization","volume":"45","author":"DC Liu","year":"1989","journal-title":"Mathematical Programming"},{"key":"pcbi.1008065.ref018","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1086\/519795","article-title":"PLINK: a tool set for whole-genome association and population-based linkage analyses","volume":"81","author":"S Purcell","year":"2007","journal-title":"The American Journal of Human Genetics"},{"key":"pcbi.1008065.ref019","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1101\/gr.083634.108","article-title":"Fast and flexible simulation of DNA sequence data","volume":"19","author":"G Chen","year":"2009","journal-title":"Genome research"},{"key":"pcbi.1008065.ref020","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.ajhg.2013.06.020","article-title":"RFmix: a discriminative modeling approach for rapid and robust local-ancestry inference","volume":"93","author":"B Maples","year":"2013","journal-title":"The American Journal of Human Genetics"},{"key":"pcbi.1008065.ref021","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1038\/nature09298","article-title":"Integrating common and rare genetic variation in diverse human populations","volume":"467","author":"International HapMap 3 Consortium","year":"2010","journal-title":"Nature"},{"key":"pcbi.1008065.ref022","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1086\/521987","article-title":"Rapid and accurate haplotype phasing and missing data inference for whole genome association studies by use of localized haplotype clustering","volume":"81","author":"SR Browning","year":"2007","journal-title":"American Journal of Human Genetics"},{"key":"pcbi.1008065.ref023","doi-asserted-by":"crossref","first-page":"2505","DOI":"10.1534\/g3.114.014274","article-title":"Spatial Localization of Recent Ancestors for Admixed Individuals","volume":"4","author":"WY Yang","year":"2014","journal-title":"G3: Genes, Genomes, Genetics"},{"key":"pcbi.1008065.ref024","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/978-3-662-48221-6_9","volume-title":"Algorithms in Bioinformatics","author":"Y Margalit","year":"2015"},{"key":"pcbi.1008065.ref025","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1534\/genetics.119.302139","article-title":"Fine-Scale Inference of Ancestry Segments Without Prior Knowledge of Admixing Groups","volume":"212","author":"M Salter-Townshend","year":"2019","journal-title":"Genetics"},{"key":"pcbi.1008065.ref026","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1038\/nprot.2010.116","article-title":"Data quality control in genetic case-control association studies","volume":"5","author":"C Anderson","year":"2010","journal-title":"Nature protocols"}],"updated-by":[{"DOI":"10.1371\/journal.pcbi.1008065","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2020,8,26]],"date-time":"2020-08-26T00:00:00Z","timestamp":1598400000000}}],"container-title":["PLOS Computational Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pcbi.1008065","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,6]],"date-time":"2022-11-06T19:30:54Z","timestamp":1667763054000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pcbi.1008065"}},"subtitle":[],"editor":[{"given":"Sergei L.","family":"Kosakovsky Pond","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,8,14]]},"references-count":26,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2020,8,14]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pcbi.1008065","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/308494","asserted-by":"object"}]},"ISSN":["1553-7358"],"issn-type":[{"value":"1553-7358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,14]]}}}