{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T06:23:04Z","timestamp":1772173384443,"version":"3.50.1"},"update-to":[{"DOI":"10.1371\/journal.pcbi.1012622","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T00:00:00Z","timestamp":1750982400000}}],"reference-count":44,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T00:00:00Z","timestamp":1750032000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011310","name":"Rural and Environment Science and Analytical Services Division","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011310","id-type":"DOI","asserted-by":"publisher"}]},{"name":"French National Research Agency and Boehringer Ingelheim Animal Health France","award":["ANR-16-IDEX-0005"],"award-info":[{"award-number":["ANR-16-IDEX-0005"]}]},{"name":"the Industrial Chair in Veterinary Public Health"},{"name":"the Scottish Government's Rural and Environment Science and Analytical Services Division"}],"content-domain":{"domain":["www.ploscompbiol.org"],"crossmark-restriction":false},"short-container-title":["PLoS Comput Biol"],"abstract":"<jats:p>We introduce the inference for populations at risk (iPAR) framework which enables modelling and estimation of spatial disease dynamics in scenarios where the population at risk is unknown or poorly mapped. This framework addresses a gap in spatial infectious disease modelling approaches, with current methods typically requiring data on the spatial distribution of the population at risk. The principles for iPAR are demonstrated in the context of a susceptible-infected disease dynamics model coupled with Bayesian inference implemented via data-augmentation Markov chain Monte Carlo (MCMC). This implementation of iPAR is tested for a range of scenarios using simulated outbreak data. Results indicate that the method can effectively estimate key properties of disease spread from spatio-temporal case reports and make useful predictions of future spread. The method is then applied to a case study exploring the 2014\u20132019 Estonian outbreak of African Swine Fever (ASF) in wild boar. Estimates of epidemiological parameters reveal evidence for long distance transmission, as well as disease control via reduction of the wild boar population in Estonia.<\/jats:p>","DOI":"10.1371\/journal.pcbi.1012622","type":"journal-article","created":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T13:45:00Z","timestamp":1750081500000},"page":"e1012622","update-policy":"https:\/\/doi.org\/10.1371\/journal.pcbi.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["iPAR: A framework for modelling and inferring information about disease spread when the populations at risk are 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