{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T06:17:52Z","timestamp":1768025872383,"version":"3.49.0"},"update-to":[{"DOI":"10.1371\/journal.pcbi.1013845","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T00:00:00Z","timestamp":1767916800000}}],"reference-count":33,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000155","name":"Division of Environmental Biology","doi-asserted-by":"publisher","award":["#2207922"],"award-info":[{"award-number":["#2207922"]}],"id":[{"id":"10.13039\/100000155","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000153","name":"Division of Biological Infrastructure","doi-asserted-by":"publisher","award":["#2412115"],"award-info":[{"award-number":["#2412115"]}],"id":[{"id":"10.13039\/100000153","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.ploscompbiol.org"],"crossmark-restriction":false},"short-container-title":["PLoS Comput Biol"],"abstract":"<jats:p>Global trade of material goods involves the potential to create pathways for the spread of infectious pathogens. One trade sector in which this synergy is clearly critical is that of wildlife trade networks. This highly complex system involves important and understudied bidirectional coupling between the economic decision making of the stakeholders and the contagion dynamics on the emergent trade network. While each of these components are independently well studied, there is a meaningful gap in understanding the feedback dynamics that can arise between them. In the present study, we describe a general game theoretic model for trade networks of goods susceptible to contagion. The primary result relies on the acyclic nature of the trade network and shows that, through the course of trading with stochastic infections, the probability of infection converges to a directly computable fixed point. This allows us to compute best responses and thus identify equilibria in the game. We present ways to use this model to describe and evaluate trade networks in terms of global and individual risk of infection under a wide variety of structural or individual modifications to the trade network. In capturing the bidirectional coupling of the system, we provide critical insight into the global and individual drivers and consequences for risks of infection inherent in and arising from the global wildlife trade, and any economic trade network with associated contagion risks.<\/jats:p>","DOI":"10.1371\/journal.pcbi.1013845","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T18:43:44Z","timestamp":1766774624000},"page":"e1013845","update-policy":"https:\/\/doi.org\/10.1371\/journal.pcbi.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["A game theoretic treatment of contagion in trade networks"],"prefix":"10.1371","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3264-5375","authenticated-orcid":true,"given":"John S.","family":"McAlister","sequence":"first","affiliation":[]},{"given":"Jesse L.","family":"Brunner","sequence":"additional","affiliation":[]},{"given":"Danielle 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Fajardo","year":"2021","journal-title":"Sci Rep."},{"issue":"3","key":"pcbi.1013845.ref007","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0152578","article-title":"Role of cattle movements in bovine tuberculosis spread in France between 2005 and 2014","volume":"11","author":"A Palisson","year":"2016","journal-title":"PLoS One."},{"issue":"11","key":"pcbi.1013845.ref008","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pstr.0000139","article-title":"Growth and globalization of the Central African wildlife economy: Insights from a 23-year study of wild meat markets on Bioko Island, Equatorial Guinea","volume":"3","author":"DV Mitchell","year":"2024","journal-title":"PLOS Sustain Transform."},{"issue":"1","key":"pcbi.1013845.ref009","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1186\/s13071-023-06000-y","article-title":"The global risk of infectious disease emergence from giant land snail invasion and pet trade","volume":"16","author":"JMW Gippet","year":"2023","journal-title":"Parasit Vectors."},{"issue":"4","key":"pcbi.1013845.ref010","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1002\/wsb.718","article-title":"Risk of pathogen spillover to bighorn sheep from domestic sheep and goat flocks on private land","volume":"40","author":"LM Heinse","year":"2016","journal-title":"Wildlife Society Bulletin."},{"key":"pcbi.1013845.ref011","article-title":"Governance principles for the wildlife trade to reduce spillover and pandemic risk","author":"D Biggs","year":"2023","journal-title":"CABI One Health."},{"issue":"1924","key":"pcbi.1013845.ref012","first-page":"20192736","article-title":"Global shifts in mammalian population trends reveal key predictors of virus spillover risk","volume":"287","author":"CK Johnson","year":"2020","journal-title":"Proc Biol Sci."},{"key":"pcbi.1013845.ref013","doi-asserted-by":"crossref","first-page":"582743","DOI":"10.3389\/fvets.2020.582743","article-title":"Emerging zoonotic diseases: should we rethink the animal-human interface?","volume":"7","author":"I Magouras","year":"2020","journal-title":"Front Vet Sci."},{"issue":"4","key":"pcbi.1013845.ref014","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1007\/s10640-020-00449-6","article-title":"Disease risk from human-environment interactions: environment and development economics for joint conservation-health policy","volume":"76","author":"HJ Albers","year":"2020","journal-title":"Environ Resour Econ (Dordr)."},{"key":"pcbi.1013845.ref015","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.jedc.2015.02.005","article-title":"Managing dynamic epidemiological risks through trade","volume":"53","author":"RD Horan","year":"2015","journal-title":"J Econ Dyn Control."},{"key":"pcbi.1013845.ref016","article-title":"Game theory approach for secured supply chain management in effective trade management","author":"W Chu","year":"2024","journal-title":"Ann Oper Res."},{"issue":"2","key":"pcbi.1013845.ref017","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/s00182-013-0366-x","article-title":"Farsighted free trade networks","volume":"42","author":"J Zhang","year":"2013","journal-title":"Int J Game Theory."},{"issue":"14","key":"pcbi.1013845.ref018","doi-asserted-by":"crossref","first-page":"7626","DOI":"10.3390\/su13147626","article-title":"Complex network game model simulation of arctic sustainable fishery trade cooperation under COVID-19","volume":"13","author":"C Zhao","year":"2021","journal-title":"Sustainability."},{"issue":"11","key":"pcbi.1013845.ref019","article-title":"Infectious disease modeling of social contagion in networks","volume":"6","author":"AL Hill","year":"2010","journal-title":"PLoS Comput Biol."},{"issue":"11","key":"pcbi.1013845.ref020","doi-asserted-by":"crossref","first-page":"118702","DOI":"10.1103\/PhysRevLett.112.118702","article-title":"Controlling contagion processes in activity driven networks","volume":"112","author":"S Liu","year":"2014","journal-title":"Phys Rev Lett."},{"key":"pcbi.1013845.ref021","doi-asserted-by":"crossref","first-page":"7723","DOI":"10.1038\/ncomms8723","article-title":"Topological data analysis of contagion maps for examining spreading processes on networks","volume":"6","author":"D Taylor","year":"2015","journal-title":"Nat Commun."},{"key":"pcbi.1013845.ref022","doi-asserted-by":"crossref","first-page":"031919","DOI":"10.1103\/PhysRevE.76.031919","article-title":"How disease models in static networks can fail to approximate disease in dynamic networks","volume":"76","author":"NH Fefferman","year":"2007","journal-title":"Phys Rev E Stat Nonlin Soft Matter Phys."},{"issue":"6","key":"pcbi.1013845.ref023","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1509\/jm.10.0088","article-title":"Seeding strategies for viral marketing: an empirical comparison","volume":"75","author":"O Hinz","year":"2011","journal-title":"Journal of Marketing."},{"issue":"4","key":"pcbi.1013845.ref024","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1080\/10835547.2013.12091371","article-title":"Strategic mortgage default in the context of a social network: an epidemiological approach","volume":"35","author":"M Seiler","year":"2013","journal-title":"Journal of Real Estate Research."},{"key":"pcbi.1013845.ref025","volume-title":"Game theory a modeling approach","author":"D Housman","year":"2023"},{"key":"pcbi.1013845.ref026","unstructured":"McAlister JS. Spillover model in wildlife trade. 2025."},{"issue":"9","key":"pcbi.1013845.ref027","doi-asserted-by":"crossref","DOI":"10.1111\/csp2.12995","article-title":"Understanding the demand for and value of pathogen-free amphibians to US pet owners","volume":"5","author":"K Cavasos","year":"2023","journal-title":"Conservat Sci and Prac."},{"issue":"2","key":"pcbi.1013845.ref028","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1007\/s10393-023-01645-8","article-title":"Attitudes and behavioral intentions of pet amphibian owners about biosecurity practices","volume":"20","author":"K Cavasos","year":"2023","journal-title":"Ecohealth."},{"issue":"6","key":"pcbi.1013845.ref029","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1111\/cobi.13336","article-title":"Network analysis of a stakeholder community combatting illegal wildlife trade","volume":"33","author":"A Moshier","year":"2019","journal-title":"Conservation Biology."},{"issue":"1","key":"pcbi.1013845.ref030","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s12992-024-01055-7","article-title":"Governance of the wildlife trade and the prevention of emerging zoonoses: a mixed methods network analysis of transnational organisations, silos, and power dynamics","volume":"20","author":"C Clifford Astbury","year":"2024","journal-title":"Global Health."},{"issue":"1","key":"pcbi.1013845.ref031","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s10393-017-1211-7","article-title":"Summarizing US wildlife trade with an eye toward assessing the risk of infectious disease introduction","volume":"14","author":"KM Smith","year":"2017","journal-title":"Ecohealth."},{"key":"pcbi.1013845.ref032","article-title":"Dealing in deadly pathogens: Taking stock of the legal trade in live wildlife and potential risks to human health","volume":"17","author":"\u00d6E Can","year":"2019","journal-title":"Glob Ecol Conserv."},{"key":"pcbi.1013845.ref033","article-title":"Compliance with animal welfare regulations: drivers and consequences","author":"C Berg","year":"2020","journal-title":"CABI Reviews."}],"updated-by":[{"DOI":"10.1371\/journal.pcbi.1013845","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T00:00:00Z","timestamp":1767916800000}}],"container-title":["PLOS Computational Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pcbi.1013845","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T18:47:08Z","timestamp":1767984428000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pcbi.1013845"}},"subtitle":[],"editor":[{"given":"Christian","family":"Hilbe","sequence":"first","affiliation":[]}],"short-title":[],"issued":{"date-parts":[[2025,12,26]]},"references-count":33,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2025,12,26]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pcbi.1013845","relation":{},"ISSN":["1553-7358"],"issn-type":[{"value":"1553-7358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,26]]}}}