{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T15:44:04Z","timestamp":1775144644764,"version":"3.50.1"},"reference-count":79,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T00:00:00Z","timestamp":1575504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"crossref","award":["BB\/J014575\/1"],"award-info":[{"award-number":["BB\/J014575\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"crossref","award":["EP\/N014529\/1"],"award-info":[{"award-number":["EP\/N014529\/1"]}],"id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"crossref"}]},{"name":"National Centre for the Replacement Refinement & Reduction of Animals in Research","award":["NC\/K500379\/1"],"award-info":[{"award-number":["NC\/K500379\/1"]}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"crossref","award":["BB\/I001816\/1"],"award-info":[{"award-number":["BB\/I001816\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000361","name":"Diabetes UK","doi-asserted-by":"crossref","award":["18\/0005886"],"award-info":[{"award-number":["18\/0005886"]}],"id":[{"id":"10.13039\/501100000361","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plosbiology.org"],"crossmark-restriction":false},"short-container-title":["PLoS Biol"],"DOI":"10.1371\/journal.pbio.3000482","type":"journal-article","created":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T13:29:30Z","timestamp":1575552570000},"page":"e3000482","update-policy":"https:\/\/doi.org\/10.1371\/journal.pbio.corrections_policy","source":"Crossref","is-referenced-by-count":7,"title":["The homeostatic dynamics of feeding behaviour identify novel mechanisms of anorectic agents"],"prefix":"10.1371","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4208-6888","authenticated-orcid":true,"given":"Thomas M.","family":"McGrath","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleanor","family":"Spreckley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aina Fernandez","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Viscomi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amin","family":"Alamshah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elina","family":"Akalestou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3417-0310","authenticated-orcid":true,"given":"Kevin G.","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4083-972X","authenticated-orcid":true,"given":"Nick S.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2019,12,5]]},"reference":[{"issue":"2","key":"pbio.3000482.ref001","doi-asserted-by":"crossref","first-page":"G183","DOI":"10.1152\/ajpgi.00434.2003","article-title":"Gastrointestinal satiety signals II. Cholecystokinin.","volume":"286","author":"TH Moran","year":"2004","journal-title":"American Journal of Physiology-Gastrointestinal and Liver Physiology"},{"issue":"1","key":"pbio.3000482.ref002","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.cmet.2010.06.001","article-title":"Assessment of feeding behavior in laboratory mice","volume":"12","author":"KL Ellacott","year":"2010","journal-title":"Cell metabolism"},{"issue":"5","key":"pbio.3000482.ref003","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.cmet.2016.04.006","article-title":"Parabrachial CGRP neurons control meal termination","volume":"23","author":"CA Campos","year":"2016","journal-title":"Cell metabolism"},{"issue":"2","key":"pbio.3000482.ref004","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1006\/jtbi.1998.0759","article-title":"Satiety splits feeding behaviour into bouts","volume":"194","author":"B Tolkamp","year":"1998","journal-title":"Journal of Theoretical Biology"},{"issue":"2","key":"pbio.3000482.ref005","doi-asserted-by":"crossref","first-page":"R378","DOI":"10.1152\/ajpregu.00661.2010","article-title":"The temporal structure of feeding behavior","volume":"301","author":"BJ Tolkamp","year":"2011","journal-title":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology"},{"issue":"1","key":"pbio.3000482.ref006","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1111\/j.1749-6632.1989.tb53236.x","article-title":"The microstructure of ingestive behavior","volume":"575","author":"JD Davis","year":"1989","journal-title":"Annals of the New York Academy of Sciences"},{"issue":"1","key":"pbio.3000482.ref007","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.conb.2011.11.004","article-title":"The surveillance state of behavioral automation","volume":"22","author":"AT Schaefer","year":"2012","journal-title":"Current opinion in neurobiology"},{"issue":"11","key":"pbio.3000482.ref008","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1038\/nn.3812","article-title":"Big behavioral data: psychology, ethology and the foundations of neuroscience","volume":"17","author":"A Gomez-Marin","year":"2014","journal-title":"Nature neuroscience"},{"issue":"1","key":"pbio.3000482.ref009","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.neuron.2014.09.005","article-title":"Toward a science of computational ethology","volume":"84","author":"DJ Anderson","year":"2014","journal-title":"Neuron"},{"key":"pbio.3000482.ref010","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1146\/annurev-neuro-070815-013845","article-title":"Computational analysis of behavior","volume":"39","author":"SR Egnor","year":"2016","journal-title":"Annual review of neuroscience"},{"key":"pbio.3000482.ref011","first-page":"2946","volume-title":"Neural Information Processing Systems 2016: Advances in neural information processing systems","author":"M Johnson","year":"2016"},{"issue":"3","key":"pbio.3000482.ref012","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.neuron.2016.12.041","article-title":"Neuroscience needs behavior: correcting a reductionist Bias","volume":"93","author":"JW Krakauer","year":"2017","journal-title":"Neuron"},{"issue":"3","key":"pbio.3000482.ref013","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1111\/j.2517-6161.1984.tb01308.x","article-title":"Piecewise-deterministic Markov processes: A general class of non-diffusion stochastic models","volume":"46","author":"MH Davis","year":"1984","journal-title":"Journal of the Royal Statistical Society Series B (Methodological)"},{"key":"pbio.3000482.ref014","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/978-3-319-12145-1_15","volume-title":"Semigroups of Operators-Theory and Applications","author":"R Rudnicki","year":"2015"},{"issue":"4","key":"pbio.3000482.ref015","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.jtbi.2008.09.044","article-title":"Simulating the formation of keratin filament networks by a piecewise-deterministic Markov process","volume":"256","author":"M Beil","year":"2009","journal-title":"Journal of theoretical biology"},{"key":"pbio.3000482.ref016","first-page":"276","volume-title":"ESAIM: Proceedings","author":"R Azas","year":"2014"},{"issue":"3","key":"pbio.3000482.ref017","doi-asserted-by":"crossref","first-page":"e0193049","DOI":"10.1371\/journal.pone.0193049","article-title":"Probabilistic models of individual and collective animal behavior","volume":"13","author":"K Bod\u2019ov\u00e1","year":"2018","journal-title":"PLoS ONE"},{"issue":"2","key":"pbio.3000482.ref018","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s10955-009-9850-x","article-title":"Non-equilibrium thermodynamics of piecewise deterministic Markov processes","volume":"137","author":"A Faggionato","year":"2009","journal-title":"Journal of Statistical Physics"},{"issue":"3","key":"pbio.3000482.ref019","doi-asserted-by":"crossref","first-page":"033206","DOI":"10.1088\/1742-5468\/aa64f3","article-title":"On the Hamiltonian structure of large deviations in stochastic hybrid systems.","volume":"2017","author":"PC Bressloff","year":"2017","journal-title":"Journal of Statistical Mechanics: Theory and Experiment"},{"key":"pbio.3000482.ref020","author":"DA Booth","year":"1978"},{"issue":"1","key":"pbio.3000482.ref021","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.physbeh.2004.04.037","article-title":"Gastric satiation is volumetric, intestinal satiation is nutritive","volume":"82","author":"TL Powley","year":"2004","journal-title":"Physiology & behavior"},{"issue":"1","key":"pbio.3000482.ref022","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1172\/JCI30227","article-title":"Gastrointestinal regulation of food intake","volume":"117","author":"DE Cummings","year":"2007","journal-title":"Journal of Clinical Investigation"},{"key":"pbio.3000482.ref023","author":"A Gelman","year":"2014"},{"key":"pbio.3000482.ref024","volume-title":"Texts in Statistical Science","author":"R McElreath","year":"2015"},{"issue":"6898","key":"pbio.3000482.ref025","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1038\/nature00887","article-title":"Gut hormone PYY3-36 physiologically inhibits food intake","volume":"418","author":"RL Batterham","year":"2002","journal-title":"Nature"},{"issue":"1","key":"pbio.3000482.ref026","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.physbeh.2011.02.038","article-title":"Peripheral glucagon-like peptide-1 (GLP-1) and satiation","volume":"105","author":"M Punjabi","year":"2011","journal-title":"Physiology & behavior"},{"issue":"1","key":"pbio.3000482.ref027","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1037\/0033-295X.111.1.128","article-title":"The timing of meals","volume":"111","author":"JH Strubbe","year":"2004","journal-title":"Psychological review"},{"issue":"11","key":"pbio.3000482.ref028","doi-asserted-by":"crossref","first-page":"s37","DOI":"10.1210\/jc.2008-1630","article-title":"Central control of body weight and appetite.","volume":"93","author":"SC Woods","year":"2008","journal-title":"The Journal of Clinical Endocrinology & Metabolism"},{"issue":"2","key":"pbio.3000482.ref029","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.physbeh.2004.02.012","article-title":"Gastrointestinal mechanisms of satiation for food","volume":"81","author":"RC Ritter","year":"2004","journal-title":"Physiology & Behavior"},{"issue":"5","key":"pbio.3000482.ref030","doi-asserted-by":"crossref","first-page":"R1568","DOI":"10.1152\/ajpregu.2001.281.5.R1568","article-title":"Parametric analysis of gastric distension responses in the parabrachial nucleus","volume":"281","author":"JP Baird","year":"2001","journal-title":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology"},{"issue":"2","key":"pbio.3000482.ref031","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1111\/j.1476-5381.2010.00885.x","article-title":"Inverse agonism of cannabinoid CB1 receptors potentiates LiCl-induced nausea in the conditioned gaping model in rats","volume":"161","author":"C Limebeer","year":"2010","journal-title":"British journal of pharmacology"},{"issue":"12","key":"pbio.3000482.ref032","doi-asserted-by":"crossref","first-page":"3193","DOI":"10.1016\/j.peptides.2006.08.001","article-title":"Dose-dependent effects of peptide YY (3\u201336) on conditioned taste aversion in rats","volume":"27","author":"PK Chelikani","year":"2006","journal-title":"Peptides"},{"issue":"11","key":"pbio.3000482.ref033","doi-asserted-by":"crossref","first-page":"4582","DOI":"10.1523\/JNEUROSCI.3729-14.2015","article-title":"Parabrachial calcitonin gene-related peptide neurons mediate conditioned taste aversion","volume":"35","author":"ME Carter","year":"2015","journal-title":"Journal of Neuroscience"},{"issue":"7","key":"pbio.3000482.ref034","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1016\/j.celrep.2018.01.067","article-title":"AgRP neurons require carnitine acetyltransferase to regulate metabolic flexibility and peripheral nutrient partitioning","volume":"22","author":"A Reichenbach","year":"2018","journal-title":"Cell reports"},{"issue":"6","key":"pbio.3000482.ref035","doi-asserted-by":"crossref","first-page":"R1606","DOI":"10.1152\/ajpregu.00817.2004","article-title":"Neuropeptide Y prepares rats for scheduled feeding","volume":"288","author":"DL Drazen","year":"2005","journal-title":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology"},{"issue":"1\u20133","key":"pbio.3000482.ref036","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.regpep.2011.07.004","article-title":"Slower gastric emptying in high-fat diet induced obese rats is associated with attenuated plasma ghrelin and elevated plasma leptin and cholecystokinin concentrations","volume":"171","author":"J Li","year":"2011","journal-title":"Regulatory peptides"},{"issue":"4","key":"pbio.3000482.ref037","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/j.1365-2982.2004.00529.x","article-title":"A non-invasive method for measurement of gastric emptying in mice: effects of altering fat content and CCK A receptor blockade.","volume":"16","author":"K Whited","year":"2004","journal-title":"Neurogastroenterology & Motility"},{"issue":"9","key":"pbio.3000482.ref038","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.2337\/dc09-0723","article-title":"Effects of a protein preload on gastric emptying, glycemia, and gut hormones after a carbohydrate meal in diet-controlled type 2 diabetes","volume":"32","author":"J Ma","year":"2009","journal-title":"Diabetes Care"},{"issue":"6340","key":"pbio.3000482.ref039","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1126\/science.aam7100","article-title":"Rapid binge-like eating and body weight gain driven by zona incerta GABA neuron activation","volume":"356","author":"X Zhang","year":"2017","journal-title":"Science"},{"issue":"9","key":"pbio.3000482.ref040","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1038\/nn.3767","article-title":"Central amygdala PKC-\u03b4 + neurons mediate the influence of multiple anorexigenic signals","volume":"17","author":"H Cai","year":"2014","journal-title":"Nature neuroscience"},{"issue":"7551","key":"pbio.3000482.ref041","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1038\/nature14416","article-title":"Neurons for hunger and thirst transmit a negative-valence teaching signal","volume":"521","author":"JN Betley","year":"2015","journal-title":"Nature"},{"issue":"5","key":"pbio.3000482.ref042","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.cell.2015.01.033","article-title":"Sensory detection of food rapidly modulates arcuate feeding circuits","volume":"160","author":"Y Chen","year":"2015","journal-title":"Cell"},{"key":"pbio.3000482.ref043","doi-asserted-by":"crossref","first-page":"e07122","DOI":"10.7554\/eLife.07122","article-title":"Arcuate hypothalamic AgRP and putative POMC neurons show opposite changes in spiking across multiple timescales","volume":"4","author":"Y Mandelblat-Cerf","year":"2015","journal-title":"Elife"},{"issue":"6","key":"pbio.3000482.ref044","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1016\/j.cell.2013.11.002","article-title":"Parallel, redundant circuit organization for homeostatic control of feeding behavior","volume":"155","author":"JN Betley","year":"2013","journal-title":"Cell"},{"issue":"3","key":"pbio.3000482.ref045","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.cell.2014.12.026","article-title":"Visualizing hypothalamic network dynamics for appetitive and consummatory behaviors","volume":"160","author":"JH Jennings","year":"2015","journal-title":"Cell"},{"issue":"4","key":"pbio.3000482.ref046","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.neuron.2011.02.016","article-title":"Reward mechanisms in obesity: new insights and future directions","volume":"69","author":"PJ Kenny","year":"2011","journal-title":"Neuron"},{"issue":"1","key":"pbio.3000482.ref047","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1017\/S0029665107005332","article-title":"Sensory processing in the brain related to the control of food intake","volume":"66","author":"ET Rolls","year":"2007","journal-title":"Proceedings of the Nutrition Society"},{"issue":"2","key":"pbio.3000482.ref048","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1523\/JNEUROSCI.1202-15.2016","article-title":"Lateral hypothalamic area glutamatergic neurons and their projections to the lateral habenula regulate feeding and reward","volume":"36","author":"AM Stamatakis","year":"2016","journal-title":"Journal of Neuroscience"},{"issue":"2","key":"pbio.3000482.ref049","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1038\/509","article-title":"Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans","volume":"19","author":"H Krude","year":"1998","journal-title":"Nature genetics"},{"issue":"9","key":"pbio.3000482.ref050","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1038\/12506","article-title":"Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin","volume":"5","author":"L Yaswen","year":"1999","journal-title":"Nature medicine"},{"issue":"3","key":"pbio.3000482.ref051","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/nn.2739","article-title":"AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training","volume":"14","author":"Y Aponte","year":"2011","journal-title":"Nature neuroscience"},{"issue":"7410","key":"pbio.3000482.ref052","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1038\/nature11270","article-title":"Deconstruction of a neural circuit for hunger","volume":"488","author":"D Atasoy","year":"2012","journal-title":"Nature"},{"issue":"8","key":"pbio.3000482.ref053","doi-asserted-by":"crossref","first-page":"3624","DOI":"10.1523\/JNEUROSCI.2742-12.2013","article-title":"Acute and long-term suppression of feeding behavior by POMC neurons in the brainstem and hypothalamus, respectively","volume":"33","author":"C Zhan","year":"2013","journal-title":"Journal of Neuroscience"},{"issue":"6","key":"pbio.3000482.ref054","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/j.neuron.2004.06.004","article-title":"Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis","volume":"42","author":"N Balthasar","year":"2004","journal-title":"Neuron"},{"issue":"6836","key":"pbio.3000482.ref055","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1038\/35078085","article-title":"Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus","volume":"411","author":"MA Cowley","year":"2001","journal-title":"Nature"},{"issue":"5667","key":"pbio.3000482.ref056","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1126\/science.1089459","article-title":"Rapid rewiring of arcuate nucleus feeding circuits by leptin","volume":"304","author":"S Pinto","year":"2004","journal-title":"Science"},{"issue":"7702","key":"pbio.3000482.ref057","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1038\/s41586-018-0049-7","article-title":"Genetic identification of leptin neural circuits in energy and glucose homeostases","volume":"556","author":"J Xu","year":"2018","journal-title":"Nature"},{"issue":"7698","key":"pbio.3000482.ref058","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/nature25511","article-title":"Encoding of danger by parabrachial CGRP neurons","volume":"555","author":"CA Campos","year":"2018","journal-title":"Nature"},{"issue":"3","key":"pbio.3000482.ref059","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.physbeh.2008.07.018","article-title":"Ileal brake: a sensible food target for appetite control. A review","volume":"95","author":"P Maljaars","year":"2008","journal-title":"Physiology & behavior"},{"issue":"8","key":"pbio.3000482.ref060","doi-asserted-by":"crossref","first-page":"3585","DOI":"10.1210\/endo.136.8.7628397","article-title":"Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV","volume":"136","author":"TJ Kieffer","year":"1995","journal-title":"Endocrinology"},{"issue":"4","key":"pbio.3000482.ref061","first-page":"377","article-title":"Cellular localization, half-life, and secretion of peptide YY","volume":"45","author":"F Lluis","year":"1989","journal-title":"Revista espanola de fisiologia"},{"issue":"1","key":"pbio.3000482.ref062","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1111\/j.1749-6632.2003.tb03176.x","article-title":"The gut hormone peptide YY regulates appetite","volume":"994","author":"RL Batterham","year":"2003","journal-title":"Annals of the New York Academy of Sciences"},{"issue":"138","key":"pbio.3000482.ref063","doi-asserted-by":"crossref","first-page":"20170736","DOI":"10.1098\/rsif.2017.0736","article-title":"Quantitative approaches to energy and glucose homeostasis: machine learning and modelling for precision understanding and prediction","volume":"15","author":"T McGrath","year":"2018","journal-title":"Journal of The Royal Society Interface"},{"issue":"1","key":"pbio.3000482.ref064","doi-asserted-by":"crossref","first-page":"11011","DOI":"10.1016\/j.ifacol.2017.08.2480","article-title":"A short-term dynamical model for ghrelin","volume":"50","author":"J Pires","year":"2017","journal-title":"IFAC-PapersOnLine."},{"issue":"3\u20134","key":"pbio.3000482.ref065","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.physbeh.2009.03.028","article-title":"The conditioned satiating effect of orosensory stimuli","volume":"97","author":"JD Davis","year":"2009","journal-title":"Physiology & behavior"},{"issue":"4","key":"pbio.3000482.ref066","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.neuron.2017.06.014","article-title":"Toward a wiring diagram understanding of appetite control","volume":"95","author":"ML Andermann","year":"2017","journal-title":"Neuron"},{"key":"pbio.3000482.ref067","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.physbeh.2013.03.024","article-title":"Forebrain networks and the control of feeding by environmental learned cues","volume":"121","author":"GD Petrovich","year":"2013","journal-title":"Physiology & behavior"},{"issue":"5","key":"pbio.3000482.ref068","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/0031-9384(79)90199-9","article-title":"Cholecystokinin, meal pattern, and the intermeal interval: can eating be stopped before it starts?","volume":"23","author":"S Hsiao","year":"1979","journal-title":"Physiology & behavior"},{"key":"pbio.3000482.ref069","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.peptides.2014.01.008","article-title":"CCK-58 elicits both satiety and satiation in rats while CCK-8 elicits only satiation","volume":"54","author":"J Overduin","year":"2014","journal-title":"Peptides"},{"issue":"3","key":"pbio.3000482.ref070","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1210\/en.2008-1221","article-title":"Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms","volume":"150","author":"EB Ruttimann","year":"2008","journal-title":"Endocrinology"},{"issue":"4","key":"pbio.3000482.ref071","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1007\/BF01316798","article-title":"Truncated GLP-1 (proglucagon 78\u2013107-amide) inhibits gastric and pancreatic functions in man","volume":"38","author":"A Wettergren","year":"1993","journal-title":"Digestive diseases and sciences"},{"issue":"10","key":"pbio.3000482.ref072","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1109\/TBME.2007.893506","article-title":"Meal simulation model of the glucose-insulin system","volume":"54","author":"C Dalla Man","year":"2007","journal-title":"IEEE Transactions on biomedical engineering"},{"issue":"8","key":"pbio.3000482.ref073","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1111\/j.1365-2036.2011.04609.x","article-title":"The role of gastric motility in the control of food intake","volume":"33","author":"P Janssen","year":"2011","journal-title":"Alimentary pharmacology & therapeutics"},{"issue":"1\u20132","key":"pbio.3000482.ref074","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.autneu.2006.01.008","article-title":"Signals for nausea and emesis: Implications for models of upper gastrointestinal diseases","volume":"125","author":"PL Andrews","year":"2006","journal-title":"Autonomic Neuroscience"},{"issue":"2","key":"pbio.3000482.ref075","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.cmet.2015.12.002","article-title":"An emerging technology framework for the neurobiology of appetite","volume":"23","author":"SM Sternson","year":"2016","journal-title":"Cell metabolism"},{"key":"pbio.3000482.ref076","doi-asserted-by":"crossref","first-page":"e27702","DOI":"10.7554\/eLife.27702","article-title":"Automated long-term recording and analysis of neural activity in behaving animals.","volume":"6","author":"AK Dhawale","year":"2017","journal-title":"eLife"},{"key":"pbio.3000482.ref077","doi-asserted-by":"crossref","DOI":"10.4148\/2475-7772.1004","article-title":"Bayesian inference for a covariance matrix","author":"I Alvarez","year":"2014"},{"key":"pbio.3000482.ref078","doi-asserted-by":"crossref","first-page":"e55","DOI":"10.7717\/peerj-cs.55","article-title":"Probabilistic programming in Python using PyMC3","volume":"2","author":"J Salvatier","year":"2016","journal-title":"PeerJ Computer Science"},{"key":"pbio.3000482.ref079","first-page":"30","article-title":"Hamiltonian Monte Carlo for hierarchical models.","volume":"79","author":"M Betancourt","year":"2015","journal-title":"Current trends in Bayesian methodology with applications"}],"container-title":["PLOS Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pbio.3000482","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T13:30:05Z","timestamp":1575552605000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pbio.3000482"}},"subtitle":[],"editor":[{"given":"Scott","family":"Kanoski","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2019,12,5]]},"references-count":79,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2019,12,5]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pbio.3000482","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/578344","asserted-by":"object"}]},"ISSN":["1545-7885"],"issn-type":[{"value":"1545-7885","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,5]]}}}