{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T19:16:34Z","timestamp":1792178194092,"version":"4.4.0"},"update-to":[{"DOI":"10.1371\/journal.pbio.3000834","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T00:00:00Z","timestamp":1602547200000}}],"reference-count":43,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000185","name":"Defense Advanced Research Projects Agency","doi-asserted-by":"publisher","award":["N66001-16-C-4058"],"award-info":[{"award-number":["N66001-16-C-4058"]}],"id":[{"id":"10.13039\/100000185","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["MOP-115178"],"award-info":[{"award-number":["MOP-115178"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Jeanne Timmins Costello Postdoctoral Fellowship"}],"content-domain":{"domain":["www.plosbiology.org"],"crossmark-restriction":false},"short-container-title":["PLoS Biol"],"DOI":"10.1371\/journal.pbio.3000834","type":"journal-article","created":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T13:54:11Z","timestamp":1601560451000},"page":"e3000834","update-policy":"https:\/\/doi.org\/10.1371\/journal.pbio.corrections_policy","source":"Crossref","is-referenced-by-count":79,"title":["tACS entrains neural activity while somatosensory input is blocked"],"prefix":"10.1371","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9433-8675","authenticated-orcid":true,"given":"Pedro G.","family":"Vieira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1837-687X","authenticated-orcid":true,"given":"Matthew R.","family":"Krause","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher C.","family":"Pack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,10,1]]},"reference":[{"issue":"1","key":"pbio.3000834.ref001","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.neuron.2010.06.005","article-title":"Endogenous electric fields may guide neocortical network activity","volume":"67","author":"F Frohlich","year":"2010","journal-title":"Neuron"},{"issue":"36","key":"pbio.3000834.ref002","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aaz2747","article-title":"Dose-dependent effects of transcranial alternating current stimulation on spike timing in awake nonhuman primates","volume":"6","author":"L Johnson","year":"2020","journal-title":"Sci Adv"},{"issue":"12","key":"pbio.3000834.ref003","doi-asserted-by":"crossref","first-page":"5747","DOI":"10.1073\/pnas.1815958116","article-title":"Transcranial alternating current stimulation entrains single-neuron activity in the primate brain","volume":"116","author":"MR Krause","year":"2019","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"34","key":"pbio.3000834.ref004","doi-asserted-by":"crossref","first-page":"11476","DOI":"10.1523\/JNEUROSCI.5252-09.2010","article-title":"Transcranial electric stimulation entrains cortical neuronal populations in rats","volume":"30","author":"S Ozen","year":"2010","journal-title":"J Neurosci"},{"issue":"1","key":"pbio.3000834.ref005","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/s41467-018-08183-w","article-title":"tACS motor system effects can be caused by transcutaneous stimulation of peripheral nerves","volume":"10","author":"B Asamoah","year":"2019","journal-title":"Nat Commun"},{"issue":"1","key":"pbio.3000834.ref006","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1038\/s41467-018-02928-3","article-title":"Direct effects of transcranial electric stimulation on brain circuits in rats and humans","volume":"9","author":"M Voroslakos","year":"2018","journal-title":"Nat Commun"},{"issue":"6","key":"pbio.3000834.ref007","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1016\/j.brs.2019.06.029","article-title":"LTD-like plasticity of the human primary motor cortex can be reversed by gamma-tACS","volume":"12","author":"A Guerra","year":"2019","journal-title":"Brain Stimul"},{"issue":"1","key":"pbio.3000834.ref008","doi-asserted-by":"crossref","first-page":"12858","DOI":"10.1038\/s41598-019-49166-1","article-title":"State-Dependent Effects of Transcranial Oscillatory Currents on the Motor System during Action Observation","volume":"9","author":"M Feurra","year":"2019","journal-title":"Sci Rep"},{"issue":"1","key":"pbio.3000834.ref009","doi-asserted-by":"crossref","first-page":"5092","DOI":"10.1038\/s41467-018-07233-7","article-title":"Immediate neurophysiological effects of transcranial electrical stimulation","volume":"9","author":"A Liu","year":"2018","journal-title":"Nat Commun"},{"issue":"6","key":"pbio.3000834.ref010","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1213\/01.ANE.0000219588.25375.36","article-title":"The role of the craniospinal nerves in mediating the antinociceptive effect of transcranial electrostimulation in the rat","volume":"102","author":"V Nekhendzy","year":"2006","journal-title":"Anesth Analg"},{"issue":"10","key":"pbio.3000834.ref011","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.jpain.2005.06.001","article-title":"Deep tissue afferents, but not cutaneous afferents, mediate transcutaneous electrical nerve stimulation-Induced antihyperalgesia","volume":"6","author":"R Radhakrishnan","year":"2005","journal-title":"J Pain"},{"issue":"1","key":"pbio.3000834.ref012","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.brs.2010.05.002","article-title":"Reducing procedural pain and discomfort associated with transcranial direct current stimulation","volume":"4","author":"JL McFadden","year":"2011","journal-title":"Brain Stimul"},{"issue":"4","key":"pbio.3000834.ref013","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1113\/JP272738","article-title":"Systematic evaluation of the impact of stimulation intensity on neuroplastic after-effects induced by transcranial direct current stimulation","volume":"595","author":"A Jamil","year":"2017","journal-title":"J Physiol"},{"key":"pbio.3000834.ref014","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.neulet.2016.06.056","article-title":"Working memory capacity differentially influences responses to tDCS and HD-tDCS in a retro-cue task","volume":"629","author":"F Gozenman","year":"2016","journal-title":"Neurosci Lett"},{"issue":"3","key":"pbio.3000834.ref015","doi-asserted-by":"crossref","first-page":"111","DOI":"10.15540\/nr.2.3.111","article-title":"High-definition tDCS of noun and verb retrieval in naming and lexical decision","volume":"2","author":"S Malyutina","year":"2015","journal-title":"NeuroRegulation"},{"issue":"20","key":"pbio.3000834.ref016","doi-asserted-by":"crossref","first-page":"3086","DOI":"10.1016\/j.cub.2017.09.020","article-title":"Transcranial Direct Current Stimulation Facilitates Associative Learning and Alters Functional Connectivity in the Primate Brain","volume":"27","author":"MR Krause","year":"2017","journal-title":"Curr Biol"},{"issue":"4","key":"pbio.3000834.ref017","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1177\/1948550617697177","article-title":"Equivalence Tests: A Practical Primer for t Tests, Correlations, and Meta-Analyses","volume":"8","author":"D Lakens","year":"2017","journal-title":"Soc Psychol Personal Sci"},{"issue":"1","key":"pbio.3000834.ref018","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/cercor\/bhs270","article-title":"A weighted and directed interareal connectivity matrix for macaque cerebral cortex","volume":"24","author":"NT Markov","year":"2014","journal-title":"Cereb Cortex"},{"issue":"8","key":"pbio.3000834.ref019","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1002\/cne.23513","article-title":"Subcortical connections of area V4 in the macaque","volume":"522","author":"R Gattass","year":"2014","journal-title":"J Comp Neurol"},{"issue":"3","key":"pbio.3000834.ref020","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1093\/cercor\/bhm061","article-title":"Cortical connections of area V4 in the macaque","volume":"18","author":"LG Ungerleider","year":"2008","journal-title":"Cereb Cortex"},{"issue":"11","key":"pbio.3000834.ref021","doi-asserted-by":"crossref","first-page":"3425","DOI":"10.1016\/j.clinph.2016.08.016","article-title":"Animal models of transcranial direct current stimulation: Methods and mechanisms","volume":"127","author":"MP Jackson","year":"2016","journal-title":"Clin Neurophysiol"},{"key":"pbio.3000834.ref022","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.18834","article-title":"Measurements and models of electric fields in the in vivo human brain during transcranial electric stimulation","volume":"6","author":"Y Huang","year":"2017","journal-title":"Elife"},{"key":"pbio.3000834.ref023","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.cortex.2019.10.006","article-title":"Modulating brain activity and behaviour with tDCS: Rumours of its death have been greatly exaggerated","volume":"123","author":"HL Filmer","year":"2020","journal-title":"Cortex"},{"key":"pbio.3000834.ref024","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/0006-8993(73)90386-7","article-title":"Synaptic delay: its effect on information transmission in the crayfish caudal photoreceptor system","volume":"51","author":"DA Harris","year":"1973","journal-title":"Brain Res"},{"key":"pbio.3000834.ref025","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1098\/rspb.1965.0016","article-title":"The Measurement of Synaptic Delay, and the Time Course of Acetylcholine Release at the Neuromuscular Junction","volume":"161","author":"B Katz","year":"1965","journal-title":"Proc R Soc Lond B Biol Sci"},{"issue":"45","key":"pbio.3000834.ref026","doi-asserted-by":"crossref","first-page":"22438","DOI":"10.1073\/pnas.1912927116","article-title":"How does transcranial alternating current stimulation entrain single-neuron activity in the primate brain?","volume":"116","author":"A Khatoun","year":"2019","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"pbio.3000834.ref027","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.brs.2018.09.010","article-title":"Can transcranial electric stimulation with multiple electrodes reach deep targets?","volume":"12","author":"Y Huang","year":"2019","journal-title":"Brain Stimul"},{"issue":"45","key":"pbio.3000834.ref028","doi-asserted-by":"crossref","first-page":"22440","DOI":"10.1073\/pnas.1914483116","article-title":"Reply to Khatoun et al.: Speculation about brain stimulation must be constrained by observation","volume":"116","author":"MR Krause","year":"2019","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"pbio.3000834.ref029","first-page":"4","article-title":"Cortical plasticity induced by different degrees of peripheral nerve injuries: a rat functional magnetic resonance imaging study under 9.4 Tesla","volume":"8","author":"R Li","year":"2013","journal-title":"J Brachial Plex Peripher Nerve Inj"},{"issue":"7","key":"pbio.3000834.ref030","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1002\/mds.27350","article-title":"Noninvasive neuromodulation in essential tremor demonstrates relief in a sham-controlled pilot trial","volume":"33","author":"PT Lin","year":"2018","journal-title":"Mov Disord"},{"issue":"1","key":"pbio.3000834.ref031","doi-asserted-by":"crossref","first-page":"4927","DOI":"10.1038\/s41598-018-23290-w","article-title":"Using high-amplitude and focused transcranial alternating current stimulation to entrain physiological tremor","volume":"8","author":"A Khatoun","year":"2018","journal-title":"Sci Rep"},{"issue":"2","key":"pbio.3000834.ref032","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.brs.2014.11.003","article-title":"Montage matters: the influence of transcranial alternating current stimulation on human physiological tremor","volume":"8","author":"AR Mehta","year":"2015","journal-title":"Brain Stimul"},{"issue":"5","key":"pbio.3000834.ref033","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1161\/STROKEAHA.108.540500","article-title":"Effects of combined peripheral nerve stimulation and brain polarization on performance of a motor sequence task after chronic stroke","volume":"40","author":"P Celnik","year":"2009","journal-title":"Stroke"},{"issue":"12","key":"pbio.3000834.ref034","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a034157","article-title":"Recording and Decoding of Vagal Neural Signals Related to Changes in Physiological Parameters and Biomarkers of Disease","volume":"9","author":"TP Zanos","year":"2019","journal-title":"Cold Spring Harb Perspect Med"},{"key":"pbio.3000834.ref035","doi-asserted-by":"crossref","unstructured":"Datta A, Krause, M.R., Pilly, P.K., Choe, J., Zanos, T.P., Thomas, C., and Pack, C.C. On comparing in vivo intracranial recordings in non-human primates to predictions of optimized transcranial electrical stimulation. Proceedings of the 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 2016.","DOI":"10.1109\/EMBC.2016.7591061"},{"issue":"6","key":"pbio.3000834.ref036","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.brs.2014.08.005","article-title":"Neurosensory effects of transcranial alternating current stimulation","volume":"7","author":"V Raco","year":"2014","journal-title":"Brain Stimul"},{"issue":"3","key":"pbio.3000834.ref037","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.cub.2013.12.041","article-title":"Entrainment of brain oscillations by transcranial alternating current stimulation","volume":"24","author":"RF Helfrich","year":"2014","journal-title":"Curr Biol"},{"issue":"24","key":"pbio.3000834.ref038","doi-asserted-by":"crossref","first-page":"8699","DOI":"10.1523\/JNEUROSCI.0971-11.2011","article-title":"Quality metrics to accompany spike sorting of extracellular signals","volume":"31","author":"DN Hill","year":"2011","journal-title":"J Neurosci"},{"issue":"1","key":"pbio.3000834.ref039","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.neuroimage.2010.01.073","article-title":"The pairwise phase consistency: a bias-free measure of rhythmic neuronal synchronization","volume":"51","author":"M Vinck","year":"2010","journal-title":"Neuroimage"},{"issue":"1","key":"pbio.3000834.ref040","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1152\/jn.00642.2010","article-title":"Removal of spurious correlations between spikes and local field potentials","volume":"105","author":"TP Zanos","year":"2011","journal-title":"Journal of neurophysiology"},{"key":"pbio.3000834.ref041","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.neuroimage.2016.03.065","article-title":"Physiological processes non-linearly affect electrophysiological recordings during transcranial electric stimulation","volume":"140","author":"N Noury","year":"2016","journal-title":"Neuroimage"},{"issue":"6634","key":"pbio.3000834.ref042","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1136\/bmj.296.6634.1454","article-title":"Calculating confidence intervals for some non-parametric analyses","volume":"296","author":"MJ Campbell","year":"1988","journal-title":"Br Med J (Clin Res Ed)"},{"key":"pbio.3000834.ref043","unstructured":"R Core Team. R: A Language and Environment for Statistical Computing. 2018."}],"updated-by":[{"DOI":"10.1371\/journal.pbio.3000834","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T00:00:00Z","timestamp":1602547200000}}],"container-title":["PLOS Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pbio.3000834","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T13:59:09Z","timestamp":1602597549000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pbio.3000834"}},"subtitle":[],"editor":[{"given":"Simon","family":"Hanslmayr","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,10,1]]},"references-count":43,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2020,10,1]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pbio.3000834","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/691022","asserted-by":"object"}]},"ISSN":["1545-7885"],"issn-type":[{"value":"1545-7885","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,1]]}}}