{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T17:08:50Z","timestamp":1791911330917,"version":"4.3.4"},"update-to":[{"DOI":"10.1371\/journal.pbio.3003277","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T00:00:00Z","timestamp":1754352000000}}],"reference-count":292,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T00:00:00Z","timestamp":1753747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014507","name":"Molson Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014507","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003151","name":"Fonds de recherche du Qu\u00e9bec \u2013 Nature et technologies","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003151","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009484","name":"Helmholtz International Research School for Teratronics, Karlsruher Institut f\u00fcr Technologie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009484","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006308","name":"Helga og Peter Kornings Fond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006308","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014507","name":"Molson Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014507","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003151","name":"Fonds de recherche du Qu\u00e9bec \u2013 Nature et technologies","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003151","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["RGPIN-2017-04265"],"award-info":[{"award-number":["RGPIN-2017-04265"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-180439"],"award-info":[{"award-number":["PJT-180439"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Brain Canada Foundation Future Leaders Fund"},{"DOI":"10.13039\/501100001804","name":"Canada Research Chairs","doi-asserted-by":"publisher","award":["CRC-2022-00169"],"award-info":[{"award-number":["CRC-2022-00169"]}],"id":[{"id":"10.13039\/501100001804","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000864","name":"Michael J. Fox Foundation for Parkinson's Research","doi-asserted-by":"publisher","award":["MJFF-021133"],"award-info":[{"award-number":["MJFF-021133"]}],"id":[{"id":"10.13039\/100000864","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Healthy Brains for Healthy Lives","award":["Discovery Grant"],"award-info":[{"award-number":["Discovery Grant"]}]}],"content-domain":{"domain":["www.plosbiology.org"],"crossmark-restriction":false},"short-container-title":["PLoS Biol"],"abstract":"<jats:p>Blood perfusion delivers oxygen and nutrients to all cells, making it a fundamental feature of brain organization. How cerebral blood perfusion maps onto micro-, meso- and macro-scale brain structure and function is therefore a key question in neuroscience. Here we analyze pseudo-continuous arterial spin labeling (ASL) data from 1305 healthy individuals in the HCP Lifespan studies (5\u201322 and 36\u2013100 years) to reconstruct a high-resolution normative cerebral blood perfusion map. At the cellular and molecular level, cerebral blood perfusion co-localizes with granular layer IV, biological pathways for maintenance of cellular relaxation potential and mitochondrial organization, and with neurotransmitter and neuropeptide receptors involved in vasomodulation. At the regional level, blood perfusion aligns with cortical arealization and is greatest in regions with high metabolic demand and resting-state functional hubs. Looking across individuals, blood perfusion is dynamic throughout the lifespan, follows micro-architectural changes in development, and maps onto individual differences in physiological changes in aging. In addition, we find that cortical atrophy in multiple neurodegenerative diseases (late-onset Alzheimer\u2019s disease, TDP-43C, and dementia with Lewy bodies) is most pronounced in regions with lower perfusion, highlighting the utility of perfusion topography as an indicator of transdiagnostic vulnerability. Finally, we show that ASL-derived perfusion can be used to delineate arterial territories in a data-driven manner, providing insights into how the vascular system is linked to human brain function. Collectively, this work highlights how cerebral blood perfusion is central to, and interlinked with, multiple structural and functional systems in the brain.<\/jats:p>","DOI":"10.1371\/journal.pbio.3003277","type":"journal-article","created":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T17:42:48Z","timestamp":1753810968000},"page":"e3003277","update-policy":"https:\/\/doi.org\/10.1371\/journal.pbio.corrections_policy","source":"Crossref","is-referenced-by-count":9,"title":["Mapping cerebral blood perfusion and its links to multi-scale brain organization across the human lifespan"],"prefix":"10.1371","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-9905-8813","authenticated-orcid":true,"given":"Asa","family":"Farahani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen-Qi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric G.","family":"Ceballos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justine Y.","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Wennberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yashar","family":"Zeighami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahsa","family":"Dadar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudine J.","family":"Gauthier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Dagher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0307-2862","authenticated-orcid":true,"given":"Bratislav","family":"Misic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,7,29]]},"reference":[{"key":"pbio.3003277.ref001","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.neuroimage.2016.11.006","article-title":"Multi-scale brain networks","volume":"160","author":"RF Betzel","year":"2017","journal-title":"NeuroImage."},{"issue":"3","key":"pbio.3003277.ref002","doi-asserted-by":"crossref","DOI":"10.1103\/RevModPhys.94.031002","article-title":"Colloquium: multiscale modeling of brain network organization","volume":"94","author":"C Presigny","year":"2022","journal-title":"Rev Mod Phys."},{"issue":"17","key":"pbio.3003277.ref003","doi-asserted-by":"crossref","first-page":"5290","DOI":"10.1523\/JNEUROSCI.16-17-05290.1996","article-title":"Morphology and physiology of cortical neurons in layer I","volume":"16","author":"S Hestrin","year":"1996","journal-title":"J Neurosci."},{"issue":"10","key":"pbio.3003277.ref004","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1038\/nrn1769","article-title":"An integrated approach to classifying neuronal phenotypes","volume":"6","author":"M Migliore","year":"2005","journal-title":"Nat Rev Neurosci."},{"issue":"8","key":"pbio.3003277.ref005","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1038\/nrn3962","article-title":"From the neuron doctrine to neural networks","volume":"16","author":"R Yuste","year":"2015","journal-title":"Nat Rev Neurosci."},{"issue":"3","key":"pbio.3003277.ref006","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/nrn.2016.182","article-title":"Micro-connectomics: probing the organization of neuronal networks at the cellular scale","volume":"18","author":"M Schr\u00f6ter","year":"2017","journal-title":"Nat Rev Neurosci."},{"issue":"7879","key":"pbio.3003277.ref007","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1038\/s41586-021-03941-1","article-title":"Morphological diversity of single neurons in molecularly defined cell types","volume":"598","author":"H Peng","year":"2021","journal-title":"Nature."},{"key":"pbio.3003277.ref008","unstructured":"Basar E. Brain function and oscillations: volume I: brain oscillations. Principles and approaches. Springer; 2012."},{"issue":"9","key":"pbio.3003277.ref009","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1038\/nrn2886","article-title":"Spiking activity propagation in neuronal networks: reconciling different perspectives on neural coding","volume":"11","author":"A Kumar","year":"2010","journal-title":"Nat Rev Neurosci."},{"issue":"1","key":"pbio.3003277.ref010","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1146\/annurev-neuro-062111-150444","article-title":"Mechanisms of gamma oscillations","volume":"35","author":"G Buzs\u00e1ki","year":"2012","journal-title":"Annu Rev Neurosci."},{"issue":"2","key":"pbio.3003277.ref011","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/s41583-018-0094-0","article-title":"Portraits of communication in neuronal networks","volume":"20","author":"G Hahn","year":"2018","journal-title":"Nat Rev Neurosci."},{"issue":"7370","key":"pbio.3003277.ref012","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1038\/nature10523","article-title":"Spatio-temporal transcriptome of the human brain","volume":"478","author":"HJ Kang","year":"2011","journal-title":"Nature."},{"issue":"7416","key":"pbio.3003277.ref013","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/nature11405","article-title":"An anatomically comprehensive atlas of the adult human brain transcriptome","volume":"489","author":"MJ Hawrylycz","year":"2012","journal-title":"Nature."},{"issue":"7495","key":"pbio.3003277.ref014","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/nature13185","article-title":"Transcriptional landscape of the prenatal human brain","volume":"508","author":"JA Miller","year":"2014","journal-title":"Nature."},{"issue":"12","key":"pbio.3003277.ref015","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1038\/nn.4156","article-title":"The psychencode project","volume":"18","author":"S Akbarian","year":"2015","journal-title":"Nat Neurosci."},{"issue":"4","key":"pbio.3003277.ref016","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1097\/WCO.0b013e32832d95db","article-title":"Receptor mapping: architecture of the human cerebral cortex","volume":"22","author":"K Zilles","year":"2009","journal-title":"Curr Opinion Neurol."},{"key":"pbio.3003277.ref017","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3389\/fnana.2017.00078","article-title":"Multiple transmitter receptors in regions and layers of the human cerebral cortex","volume":"11","author":"K Zilles","year":"2017","journal-title":"Front Neuroanat."},{"issue":"11","key":"pbio.3003277.ref018","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1038\/s41593-022-01186-3","article-title":"Mapping neurotransmitter systems to the structural and functional organization of the human neocortex","volume":"25","author":"JY Hansen","year":"2022","journal-title":"Nat Neurosci."},{"issue":"1","key":"pbio.3003277.ref019","first-page":"120","article-title":"A high-resolution in vivo atlas of the human brain\u2019s serotonin system","volume":"37","author":"V Beliveau","year":"2017","journal-title":"J Neurosci."},{"key":"pbio.3003277.ref020","doi-asserted-by":"crossref","first-page":"117878","DOI":"10.1016\/j.neuroimage.2021.117878","article-title":"A high-resolution in vivo atlas of the human brain\u2019s benzodiazepine binding site of GABAA receptors","volume":"232","author":"M N\u00f8rgaard","year":"2021","journal-title":"NeuroImage."},{"issue":"7","key":"pbio.3003277.ref021","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1038\/s41593-023-01351-2","article-title":"Gradients of neurotransmitter receptor expression in the macaque cortex","volume":"26","author":"S Froudist-Walsh","year":"2023","journal-title":"Nat Neurosci."},{"issue":"6226","key":"pbio.3003277.ref022","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1126\/science.aaa1934","article-title":"Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq","volume":"347","author":"A Zeisel","year":"2015","journal-title":"Science."},{"issue":"1","key":"pbio.3003277.ref023","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/nbt.4038","article-title":"Integrative single-cell analysis of transcriptional and epigenetic states in the human adult brain","volume":"36","author":"BB Lake","year":"2017","journal-title":"Nat Biotechnol."},{"issue":"1","key":"pbio.3003277.ref024","doi-asserted-by":"crossref","first-page":"8868","DOI":"10.1038\/s41598-018-27293-5","article-title":"Brain cell type specific gene expression and co-expression network architectures","volume":"8","author":"AT McKenzie","year":"2018","journal-title":"Sci Rep."},{"issue":"1","key":"pbio.3003277.ref025","first-page":"1","article-title":"Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders","volume":"11","author":"J Seidlitz","year":"2020","journal-title":"Nat Commun."},{"issue":"6139","key":"pbio.3003277.ref026","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1126\/science.1235381","article-title":"BigBrain: an ultrahigh-resolution 3D human brain model","volume":"340","author":"K Amunts","year":"2013","journal-title":"Science."},{"issue":"5","key":"pbio.3003277.ref027","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3000284","article-title":"Microstructural and functional gradients are increasingly dissociated in transmodal cortices","volume":"17","author":"C Paquola","year":"2019","journal-title":"PLoS Biol."},{"issue":"7","key":"pbio.3003277.ref028","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1093\/cercor\/bhy074","article-title":"Mapping cortical laminar structure in the 3D BigBrain","volume":"28","author":"K Wagstyl","year":"2018","journal-title":"Cerebral Cortex."},{"issue":"4","key":"pbio.3003277.ref029","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3000678","article-title":"BigBrain 3D atlas of cortical layers: cortical and laminar thickness gradients diverge in sensory and motor cortices","volume":"18","author":"K Wagstyl","year":"2020","journal-title":"PLoS Biol."},{"issue":"41","key":"pbio.3003277.ref030","doi-asserted-by":"crossref","first-page":"17757","DOI":"10.1073\/pnas.1010459107","article-title":"Regional aerobic glycolysis in the human brain","volume":"107","author":"SN Vaishnavi","year":"2010","journal-title":"Proc Natl Acad Sci USA."},{"issue":"50","key":"pbio.3003277.ref031","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adi7632","article-title":"An energy costly architecture of neuromodulators for human brain evolution and cognition","volume":"9","author":"G Castrillon","year":"2023","journal-title":"Sci Adv."},{"issue":"12","key":"pbio.3003277.ref032","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1038\/nn.3862","article-title":"A hierarchy of intrinsic timescales across primate cortex","volume":"17","author":"JD Murray","year":"2014","journal-title":"Nat Neurosci."},{"issue":"4","key":"pbio.3003277.ref033","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1093\/brain\/awy035","article-title":"Atlas of the normal intracranial electroencephalogram: neurophysiological awake activity in different cortical areas","volume":"141","author":"B Frauscher","year":"2018","journal-title":"Brain."},{"key":"pbio.3003277.ref034","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.62116","article-title":"Topographic gradients of intrinsic dynamics across neocortex","volume":"9","author":"G Shafiei","year":"2020","journal-title":"eLife."},{"key":"pbio.3003277.ref035","article-title":"Neuronal timescales are functionally dynamic and shaped by cortical microarchitecture","volume":"9","author":"R Gao","year":"2020","journal-title":"eLife."},{"issue":"3","key":"pbio.3003277.ref036","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/s41583-020-0262-x","article-title":"Macroscopic gradients of synaptic excitation and inhibition in the neocortex","volume":"21","author":"XJ Wang","year":"2020","journal-title":"Nat Rev Neurosci."},{"key":"pbio.3003277.ref037","article-title":"From local properties to brain-wide organization: a review of intraregional temporal features in functional magnetic resonance imaging data","author":"B Wang","year":"2023","journal-title":"Hum Brain Mapp."},{"issue":"5","key":"pbio.3003277.ref038","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1242\/dev.028845","article-title":"Neurovascular development uses VEGF-A signaling to regulate blood vessel ingression into the neural tube","volume":"136","author":"JM James","year":"2009","journal-title":"Development."},{"key":"pbio.3003277.ref039","doi-asserted-by":"crossref","DOI":"10.1093\/cercor\/bhp040","article-title":"Neurovascular congruence during cerebral cortical development","volume":"19","author":"D Stubbs","year":"2009","journal-title":"Cerebral Cortex."},{"issue":"1","key":"pbio.3003277.ref040","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1146\/annurev-neuro-060909-152829","article-title":"Connecting vascular and nervous system development: angiogenesis and the blood-brain barrier","volume":"33","author":"SJ Tam","year":"2010","journal-title":"Annu Rev Neurosci."},{"issue":"1","key":"pbio.3003277.ref041","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1146\/annurev-neuro-071714-033835","article-title":"Neuronal and vascular interactions","volume":"38","author":"BJ Andreone","year":"2015","journal-title":"Annu Rev Neurosci."},{"issue":"1","key":"pbio.3003277.ref042","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.devcel.2018.01.023","article-title":"Neurovascular communication during CNS development","volume":"45","author":"I Paredes","year":"2018","journal-title":"Developm Cell."},{"issue":"2","key":"pbio.3003277.ref043","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.neubiorev.2004.03.002","article-title":"The selfish brain: competition for energy resources","volume":"28","author":"A Peters","year":"2004","journal-title":"Neurosci Biobehav Rev."},{"issue":"6","key":"pbio.3003277.ref044","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/S0924-977X(02)00098-6","article-title":"Blood\u2013brain barrier, brain metabolism and cerebral blood flow","volume":"12","author":"O Paulson","year":"2002","journal-title":"Eur Neuropsychopharmacol."},{"issue":"8","key":"pbio.3003277.ref045","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.arcmed.2014.11.018","article-title":"Role of the blood\u2013brain barrier in the nutrition of the central nervous system","volume":"45","author":"P Campos-Bedolla","year":"2014","journal-title":"Archiv Med Res."},{"issue":"1","key":"pbio.3003277.ref046","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.neuron.2017.07.030","article-title":"The neurovascular unit coming of age: a journey through neurovascular coupling in health and disease","volume":"96","author":"C Iadecola","year":"2017","journal-title":"Neuron."},{"issue":"6","key":"pbio.3003277.ref047","doi-asserted-by":"crossref","DOI":"10.1161\/STR.0000000000000431","article-title":"The neurovasculome: key roles in brain health and cognitive impairment: a scientific statement from the American Heart Association\/American Stroke Association","volume":"54","author":"C Iadecola","year":"2023","journal-title":"Stroke."},{"issue":"7048","key":"pbio.3003277.ref048","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1038\/nature03875","article-title":"Common mechanisms of nerve and blood vessel wiring","volume":"436","author":"P Carmeliet","year":"2005","journal-title":"Nature."},{"issue":"7347","key":"pbio.3003277.ref049","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1038\/nature10144","article-title":"Molecular mechanisms and clinical applications of angiogenesis","volume":"473","author":"P Carmeliet","year":"2011","journal-title":"Nature."},{"issue":"4","key":"pbio.3003277.ref050","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1161\/CIRCRESAHA.108.188144","article-title":"Guidance of vascular development","volume":"104","author":"B Larrivee","year":"2009","journal-title":"Circulat Res."},{"issue":"11","key":"pbio.3003277.ref051","doi-asserted-by":"crossref","first-page":"3855","DOI":"10.1073\/pnas.83.11.3855","article-title":"Developing brain produces an angiogenesis factor.","volume":"83","author":"W Risau","year":"1986","journal-title":"Proc Natl Acad Sci USA."},{"issue":"5","key":"pbio.3003277.ref052","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/S0959-437X(00)00124-6","article-title":"Vascular developmental biology: getting nervous","volume":"10","author":"DT Shima","year":"2000","journal-title":"Curr Opinion Genet Develop."},{"issue":"9","key":"pbio.3003277.ref053","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1038\/nrg1158","article-title":"Blood vessels and nerves: common signals, pathways and diseases","volume":"4","author":"P Carmeliet","year":"2003","journal-title":"Nat Rev Genet."},{"issue":"1","key":"pbio.3003277.ref054","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1146\/annurev-cellbio-100818-125142","article-title":"Neurovascular interactions in the nervous system","volume":"35","author":"M Segarra","year":"2019","journal-title":"Annu Rev Cell Dev Biol."},{"issue":"1","key":"pbio.3003277.ref055","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0012-1606(02)00045-3","article-title":"Neurovascular congruence results from a shared patterning mechanism that utilizes Semaphorin3A and Neuropilin-1","volume":"255","author":"D Bates","year":"2003","journal-title":"Develop Biol."},{"issue":"1","key":"pbio.3003277.ref056","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1152\/ajplegacy.1945.143.1.53","article-title":"The determination of cerebral blood flow in man by the use of nitrous oxide in low concentrations","volume":"143","author":"SS Kety","year":"1945","journal-title":"Am J Physiol Legacy Content."},{"issue":"4","key":"pbio.3003277.ref057","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1172\/JCI101994","article-title":"The nitrous oxide method for the quantitative determination of cerebral blood flow in man: theory, procedure and normal values 1","volume":"27","author":"SS Kety","year":"1948","journal-title":"J Clin Invest."},{"issue":"2","key":"pbio.3003277.ref058","first-page":"259","article-title":"Brain SPECT in clinical practice. Part I: perfusion","volume":"42","author":"AM Catafau","year":"2001","journal-title":"J Nucl Med."},{"issue":"4","key":"pbio.3003277.ref059","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1002\/jmri.21093","article-title":"Absolute quantification of cerebral blood flow in normal volunteers: correlation between Xe-133 SPECT and dynamic susceptibility contrast MRI","volume":"26","author":"L Knutsson","year":"2007","journal-title":"Magnet Resonan Imaging."},{"issue":"6","key":"pbio.3003277.ref060","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1097\/00004728-198012000-00001","article-title":"Quantitative measurement of regional cerebral blood flow and oxygen metabolism in man using 15O and positron emission tomography","volume":"4","author":"RSJ Frackowiak","year":"1980","journal-title":"J Comput Assist Tomography."},{"issue":"5","key":"pbio.3003277.ref061","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1177\/0271678X16636393","article-title":"Comparison of cerebral blood flow measurement with [15O]-water positron emission tomography and arterial spin labeling magnetic resonance imaging: a systematic review","volume":"36","author":"AP Fan","year":"2016","journal-title":"J Cereb Blood Flow Metab."},{"issue":"5","key":"pbio.3003277.ref062","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1002\/mrm.1910360511","article-title":"High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part II: Experimental comparison and preliminary results","volume":"36","author":"L \u00d8stergaard","year":"1996","journal-title":"Magnet Resonan Med."},{"issue":"4","key":"pbio.3003277.ref063","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1097\/00004647-199804000-00011","article-title":"Absolute cerebral blood flow and blood volume measured by magnetic resonance imaging bolus tracking: comparison with positron emission tomography values","volume":"18","author":"L \u00d8stergaard","year":"1998","journal-title":"J Cereb Blood Flow Metabol."},{"issue":"2","key":"pbio.3003277.ref064","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1097\/RMR.0b013e31821e53f5","article-title":"Perfusion MRI using dynamic-susceptibility contrast MRI: quantification issues in patient studies","volume":"21","author":"F Calamante","year":"2010","journal-title":"Topics Magnet Reson Imaging."},{"issue":"4","key":"pbio.3003277.ref065","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1002\/mrm.25006","article-title":"Dynamic susceptibility contrast MRI with a prebolus contrast agent administration design for improved absolute quantification of perfusion","volume":"72","author":"L Knutsson","year":"2013","journal-title":"Magn Reson Med."},{"issue":"1","key":"pbio.3003277.ref066","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/mrm.1910230106","article-title":"Perfusion imaging","volume":"23","author":"JA Detre","year":"1992","journal-title":"Magnet Resonance Med."},{"issue":"1","key":"pbio.3003277.ref067","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1073\/pnas.89.1.212","article-title":"Magnetic resonance imaging of perfusion using spin inversion of arterial water","volume":"89","author":"DS Williams","year":"1992","journal-title":"Proc Natl Acad Sci USA."},{"issue":"2","key":"pbio.3003277.ref068","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1148\/radiology.208.2.9680569","article-title":"Multisection cerebral blood flow MR imaging with continuous arterial spin labeling","volume":"208","author":"DC Alsop","year":"1998","journal-title":"Radiology."},{"issue":"1","key":"pbio.3003277.ref069","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1002\/mrm.10180","article-title":"Improved accuracy of human cerebral blood perfusion measurements using arterial spin labeling: accounting for capillary water permeability","volume":"48","author":"LM Parkes","year":"2002","journal-title":"Magnet Resonance Med."},{"issue":"3","key":"pbio.3003277.ref070","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1017\/S1355617707070646","article-title":"Measurement of cerebral perfusion with arterial spin labeling: Part 1. Methods","volume":"13","author":"TT LIU","year":"2007","journal-title":"J Int Neuropsychol Soc."},{"issue":"1","key":"pbio.3003277.ref071","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1002\/mrm.25197","article-title":"Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: a consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia","volume":"73","author":"DC Alsop","year":"2014","journal-title":"Magnet Resonance Med."},{"issue":"2","key":"pbio.3003277.ref072","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1148\/radiol.2016150789","article-title":"Arterial spin labeling perfusion of the brain: emerging clinical applications","volume":"281","author":"S Haller","year":"2016","journal-title":"Radiology."},{"key":"pbio.3003277.ref073","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1016\/j.neuroimage.2018.09.060","article-title":"Extending the human connectome project across ages: imaging protocols for the lifespan development and aging projects","volume":"183","author":"MP Harms","year":"2018","journal-title":"NeuroImage."},{"key":"pbio.3003277.ref074","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.neuroimage.2018.08.050","article-title":"The lifespan human connectome project in development: a large-scale study of brain connectivity development in 5\u201321 year olds","volume":"183","author":"LH Somerville","year":"2018","journal-title":"NeuroImage."},{"key":"pbio.3003277.ref075","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.neuroimage.2018.10.009","article-title":"The lifespan human connectome project in aging: an overview","volume":"185","author":"SY Bookheimer","year":"2019","journal-title":"Neuroimage."},{"issue":"7906","key":"pbio.3003277.ref076","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/s41586-022-04554-y","article-title":"Brain charts for the human lifespan","volume":"604","author":"RA Bethlehem","year":"2022","journal-title":"Nature."},{"issue":"4560","key":"pbio.3003277.ref077","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1126\/science.7089587","article-title":"Sex and handedness differences in cerebral blood flow during rest and cognitive activity","volume":"217","author":"RC Gur","year":"1982","journal-title":"Science."},{"issue":"7","key":"pbio.3003277.ref078","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1212\/WNL.34.7.855","article-title":"Cerebral blood flow changes in benign aging and cerebrovascular disease","volume":"34","author":"TG Shaw","year":"1984","journal-title":"Neurology."},{"issue":"6","key":"pbio.3003277.ref079","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1038\/jcbfm.1988.133","article-title":"Sex differences in regional cerebral blood flow","volume":"8","author":"G Rodriguez","year":"1988","journal-title":"J Cereb Blood Flow Metab."},{"issue":"1","key":"pbio.3003277.ref080","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0165-1781(89)90009-7","article-title":"Sex roles and regional cerebral blood flow","volume":"27","author":"DG Daniel","year":"1989","journal-title":"Psychiatry Res."},{"issue":"2","key":"pbio.3003277.ref081","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1093\/schbul\/16.2.247","article-title":"Gender differences in regional cerebral blood flow","volume":"16","author":"RE Gur","year":"1990","journal-title":"Schizophrenia Bullet."},{"issue":"4","key":"pbio.3003277.ref082","first-page":"559","article-title":"Gender differences in cerebral blood flow as a function of cognitive state with PET","volume":"37","author":"G Esposito","year":"1996","journal-title":"J Nucl Med."},{"issue":"7","key":"pbio.3003277.ref083","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1177\/0271678X16668536","article-title":"Sex differences of human cortical blood flow and energy metabolism","volume":"37","author":"J Aanerud","year":"2016","journal-title":"J Cereb Blood Flow Metab."},{"issue":"4","key":"pbio.3003277.ref084","doi-asserted-by":"crossref","first-page":"4911","DOI":"10.18632\/aging.202673","article-title":"Sex and age-related differences in cerebral blood flow investigated using pseudo-continuous arterial spin labeling magnetic resonance imaging","volume":"13","author":"JS Alisch","year":"2021","journal-title":"Aging (Albany NY)."},{"key":"pbio.3003277.ref085","doi-asserted-by":"crossref","first-page":"117807","DOI":"10.1016\/j.neuroimage.2021.117807","article-title":"Characterizing cerebral hemodynamics across the adult lifespan with arterial spin labeling MRI data from the human connectome project-aging","volume":"230","author":"MR Juttukonda","year":"2021","journal-title":"NeuroImage."},{"issue":"7615","key":"pbio.3003277.ref086","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/nature18933","article-title":"A multi-modal parcellation of human cerebral cortex","volume":"536","author":"MF Glasser","year":"2016","journal-title":"Nature."},{"issue":"11","key":"pbio.3003277.ref087","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1038\/s41593-020-00711-6","article-title":"Topographic organization of the human subcortex unveiled with functional connectivity gradients","volume":"23","author":"Y Tian","year":"2020","journal-title":"Nat Neurosci."},{"issue":"9","key":"pbio.3003277.ref088","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1038\/s41593-018-0195-0","article-title":"Hierarchy of transcriptomic specialization across human cortex captured by structural neuroimaging topography","volume":"21","author":"JB Burt","year":"2018","journal-title":"Nat Neurosci."},{"issue":"10","key":"pbio.3003277.ref089","doi-asserted-by":"crossref","first-page":"6207","DOI":"10.1093\/cercor\/bhac496","article-title":"Auditory cortical connectivity in humans","volume":"33","author":"ET Rolls","year":"2022","journal-title":"Cerebral Cortex."},{"key":"pbio.3003277.ref090","doi-asserted-by":"crossref","unstructured":"Magistretti J, Allaman I. Brain energy and metabolism. Neuroscience in the 21st Century: From Basic to Clinical. Springer; 2022. p. 2197\u2013227.","DOI":"10.1007\/978-3-030-88832-9_56"},{"issue":"5","key":"pbio.3003277.ref091","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1073\/pnas.1214900110","article-title":"Coupling of functional connectivity and regional cerebral blood flow reveals a physiological basis for network hubs of the human brain","volume":"110","author":"X Liang","year":"2013","journal-title":"Proc Natl Acad Sci USA."},{"issue":"2","key":"pbio.3003277.ref092","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.cell.2012.02.052","article-title":"Large-scale cellular-resolution gene profiling in human neocortex reveals species-specific molecular signatures","volume":"149","author":"H Zeng","year":"2012","journal-title":"Cell."},{"issue":"5","key":"pbio.3003277.ref093","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/0361-9230(81)90007-1","article-title":"Cortical blood vessels of the human brain","volume":"7","author":"HM Duvernoy","year":"1981","journal-title":"Brain Res Bullet."},{"issue":"7","key":"pbio.3003277.ref094","doi-asserted-by":"crossref","first-page":"2467","DOI":"10.1007\/s00429-019-01919-4","article-title":"High resolution atlas of the venous brain vasculature from 7 T quantitative susceptibility maps","volume":"224","author":"J Huck","year":"2019","journal-title":"Brain Struct Funct."},{"key":"pbio.3003277.ref095","doi-asserted-by":"crossref","first-page":"118724","DOI":"10.1016\/j.neuroimage.2021.118724","article-title":"Laminar perfusion imaging with zoomed arterial spin labeling at 7 Tesla","volume":"245","author":"X Shao","year":"2021","journal-title":"NeuroImage."},{"issue":"4","key":"pbio.3003277.ref096","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/ana.410040402","article-title":"Local cerebral glucose utilization in the normal conscious macaque monkey","volume":"4","author":"C Kennedy","year":"1978","journal-title":"Annals Neurol."},{"issue":"10","key":"pbio.3003277.ref097","doi-asserted-by":"crossref","first-page":"3673","DOI":"10.1093\/cercor\/bhu221","article-title":"Vascular supply of the cerebral cortex is specialized for cell layers but not columns","volume":"25","author":"DL Adams","year":"2014","journal-title":"Cereb Cortex."},{"key":"pbio.3003277.ref098","article-title":"Mapping vascular network architecture in primate brain using ferumoxytol-weighted laminar MRI","author":"JA Autio","year":"2024","journal-title":"bioRxiv."},{"issue":"4","key":"pbio.3003277.ref099","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/j.neuroimage.2005.11.013","article-title":"Cortical layer-dependent BOLD and CBV responses measured by spin-echo and gradient-echo fMRI: insights into hemodynamic regulation","volume":"30","author":"F Zhao","year":"2006","journal-title":"NeuroImage."},{"key":"pbio.3003277.ref100","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.ics.2004.04.024","article-title":"Cortical layer-dependent CBF changes induced by neural activity","volume":"1265","author":"S-G Kim","year":"2004","journal-title":"Int Congr Ser."},{"issue":"7","key":"pbio.3003277.ref101","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1038\/nn.3426","article-title":"The cortical angiome: an interconnected vascular network with noncolumnar patterns of blood flow","volume":"16","author":"P Blinder","year":"2013","journal-title":"Nat Neurosci."},{"issue":"4","key":"pbio.3003277.ref102","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2020.01.028","article-title":"Mapping the fine-scale organization and plasticity of the brain vasculature","volume":"180","author":"C Kirst","year":"2020","journal-title":"Cell."},{"issue":"12","key":"pbio.3003277.ref103","doi-asserted-by":"crossref","first-page":"110978","DOI":"10.1016\/j.celrep.2022.110978","article-title":"Quantitative relationship between cerebrovascular network and neuronal cell types in mice","volume":"39","author":"Y Wu","year":"2022","journal-title":"Cell Reports."},{"issue":"1","key":"pbio.3003277.ref104","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/75556","article-title":"Gene ontology: tool for the unification of biology","volume":"25","author":"M Ashburner","year":"2000","journal-title":"Nat Genet."},{"issue":"1","key":"pbio.3003277.ref105","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.1038\/s41467-021-22862-1","article-title":"Overcoming false-positive gene-category enrichment in the analysis of spatially resolved transcriptomic brain atlas data","volume":"12","author":"BD Fulcher","year":"2021","journal-title":"Nat Commun."},{"key":"pbio.3003277.ref106","doi-asserted-by":"crossref","unstructured":"Ceballos EG, Farahani A, Liu ZQ, Milisav F, Hansen JY, Dagher A. Mapping neuropeptide signaling in the human brain. bioRxiv. 2024. p. 2024-12.","DOI":"10.1101\/2024.12.11.627947"},{"issue":"2","key":"pbio.3003277.ref107","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s10571-010-9605-x","article-title":"Brain pericytes: emerging concepts and functional roles in brain homeostasis","volume":"31","author":"M Kamouchi","year":"2010","journal-title":"Cell Mol Neurobiol."},{"issue":"7693","key":"pbio.3003277.ref108","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1038\/nature25739","article-title":"A molecular atlas of cell types and zonation in the brain vasculature","volume":"554","author":"M Vanlandewijck","year":"2018","journal-title":"Nature."},{"key":"pbio.3003277.ref109","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.nbd.2016.04.004","article-title":"Energy deficit in parvalbumin neurons leads to circuit dysfunction, impaired sensory gating and social disability","volume":"93","author":"M Inan","year":"2016","journal-title":"Neurobiol Dis."},{"key":"pbio.3003277.ref110","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.nbd.2015.08.005","article-title":"The interneuron energy hypothesis: implications for brain disease","volume":"90","author":"O Kann","year":"2016","journal-title":"Neurobiol Dis."},{"key":"pbio.3003277.ref111","first-page":"100121","article-title":"Physiological features of parvalbumin-expressing GABAergic interneurons contributing to high-frequency oscillations in the cerebral cortex","author":"KD Milicevic","year":"2023","journal-title":"Curr Res Neurobiol."},{"issue":"12","key":"pbio.3003277.ref112","doi-asserted-by":"crossref","first-page":"4954","DOI":"10.1038\/s41380-023-02168-y","article-title":"Fast-spiking parvalbumin-positive interneurons in brain physiology and Alzheimer\u2019s disease","volume":"28","author":"S Hijazi","year":"2023","journal-title":"Mol Psychiatry."},{"issue":"11","key":"pbio.3003277.ref113","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1038\/s41592-022-01625-w","article-title":"Neuromaps: structural and functional interpretation of brain maps","volume":"19","author":"RD Markello","year":"2022","journal-title":"Nat Methods."},{"issue":"4","key":"pbio.3003277.ref114","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/S0306-4522(98)00196-1","article-title":"Endothelial expression of the 5-hydroxytryptamine1B antimigraine drug receptor in rat and human brain microvessels","volume":"86","author":"M Riad","year":"1998","journal-title":"Neuroscience."},{"issue":"6","key":"pbio.3003277.ref115","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1038\/sj.bjp.0702773","article-title":"Contractile 5-HT1B receptors in human cerebral arteries: pharmacological characterization and localization with immunocytochemistry","volume":"128","author":"T Nilsson","year":"1999","journal-title":"Br J Pharmacol."},{"issue":"1","key":"pbio.3003277.ref116","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-22444-0","article-title":"Cerebral blood flow predicts differential neurotransmitter activity","volume":"8","author":"J Dukart","year":"2018","journal-title":"Sci Rep."},{"issue":"18","key":"pbio.3003277.ref117","doi-asserted-by":"crossref","first-page":"4411","DOI":"10.3390\/ijms20184411","article-title":"Vascular endothelial cell biology: an update","volume":"20","author":"A Kr\u00fcger-Genge","year":"2019","journal-title":"IJMS."},{"key":"pbio.3003277.ref118","doi-asserted-by":"crossref","unstructured":"Tanveer J, Baig A, Rubeen R, Qureshi SR, Bashir N, Khan K. Unlocking the mysteries: serotonin receptor networks explored. In: Serotonin-neurotransmitter and hormone of brain, bowels and blood. IntechOpen; 2024.","DOI":"10.5772\/intechopen.1004061"},{"issue":"4","key":"pbio.3003277.ref119","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1002\/jmri.20839","article-title":"Age dependence of cerebral perfusion assessed by magnetic resonance continuous arterial spin labeling","volume":"25","author":"L Biagi","year":"2007","journal-title":"Magnet Resonance Imaging."},{"issue":"6","key":"pbio.3003277.ref120","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1093\/cercor\/bhq224","article-title":"Alterations in cerebral metabolic rate and blood supply across the adult lifespan","volume":"21","author":"H Lu","year":"2010","journal-title":"Cerebral Cortex."},{"issue":"3","key":"pbio.3003277.ref121","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1002\/mrm.23286","article-title":"Arterial spin labeling MRI study of age and gender effects on brain perfusion hemodynamics","volume":"68","author":"Y Liu","year":"2011","journal-title":"Magnetic Resonance Med."},{"issue":"23","key":"pbio.3003277.ref122","doi-asserted-by":"crossref","first-page":"8643","DOI":"10.1073\/pnas.1400178111","article-title":"Impact of puberty on the evolution of cerebral perfusion during adolescence","volume":"111","author":"TD Satterthwaite","year":"2014","journal-title":"Proc Natl Acad Sci USA."},{"issue":"2","key":"pbio.3003277.ref123","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1002\/jmri.25938","article-title":"Arterial-spin-labeling (ASL) perfusion MRI predicts cognitive function in elderly individuals: a 4-year longitudinal study","volume":"48","author":"JB De Vis","year":"2018","journal-title":"J Magnet Resonance Imaging."},{"key":"pbio.3003277.ref124","article-title":"The organization of the human cerebral cortex estimated by intrinsic functional connectivity","author":"BT Yeo","year":"2011","journal-title":"J Neurophysiol."},{"issue":"29","key":"pbio.3003277.ref125","doi-asserted-by":"crossref","first-page":"13135","DOI":"10.1073\/pnas.1001229107","article-title":"Similar patterns of cortical expansion during human development and evolution","volume":"107","author":"J Hill","year":"2010","journal-title":"Proc Natl Acad Sci USA."},{"issue":"9","key":"pbio.3003277.ref126","doi-asserted-by":"crossref","first-page":"3095","DOI":"10.1093\/cercor\/bhx179","article-title":"Local-global parcellation of the human cerebral cortex from intrinsic functional connectivity MRI","volume":"28","author":"A Schaefer","year":"2017","journal-title":"Cerebral Cortex."},{"issue":"3","key":"pbio.3003277.ref127","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1203\/00006450-199309000-00028","article-title":"Developmental and physiologic changes in cerebral blood flow velocity","volume":"34","author":"I Horiuchi","year":"1993","journal-title":"Pediatr Res."},{"issue":"5","key":"pbio.3003277.ref128","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1203\/01.PDR.0000182579.52820.C3","article-title":"Development of cerebral blood flow volume in preterm neonates during the first two weeks of life","volume":"58","author":"M Kehrer","year":"2005","journal-title":"Pediatr Res."},{"issue":"3","key":"pbio.3003277.ref129","doi-asserted-by":"crossref","first-page":"593","DOI":"10.3174\/ajnr.A3728","article-title":"Regional cerebral blood flow in children from 3 to 5 months of age","volume":"35","author":"AF Duncan","year":"2013","journal-title":"AJNR Am J Neuroradiol."},{"issue":"1","key":"pbio.3003277.ref130","article-title":"Age-related changes of normal cerebral and cardiac blood flow in children and adults aged 7 months to 61 years","volume":"5","author":"C Wu","year":"2016","journal-title":"J Am Heart Assoc."},{"key":"pbio.3003277.ref131","doi-asserted-by":"crossref","first-page":"116224","DOI":"10.1016\/j.neuroimage.2019.116224","article-title":"Cerebral blood flow increases across early childhood","volume":"204","author":"D Paniukov","year":"2020","journal-title":"NeuroImage."},{"key":"pbio.3003277.ref132","article-title":"Infant brain regional cerebral blood flow increases supporting emergence of the default-mode network","volume":"12","author":"Q Yu","year":"2023","journal-title":"eLife."},{"key":"pbio.3003277.ref133","article-title":"Spatiotemporal cerebral blood flow dynamics underlies emergence of the limbic-sensorimotor-association cortical gradient in human infancy","author":"M Ouyang","year":"2024","journal-title":"Nat Commun."},{"issue":"10","key":"pbio.3003277.ref134","doi-asserted-by":"crossref","first-page":"2681","DOI":"10.1113\/JP271056","article-title":"Developmental trajectories of cerebrovascular reactivity in healthy children and young adults assessed with magnetic resonance imaging","volume":"594","author":"J Leung","year":"2016","journal-title":"J Physiol."},{"issue":"32","key":"pbio.3003277.ref135","doi-asserted-by":"crossref","first-page":"13281","DOI":"10.1073\/pnas.1105108108","article-title":"Extraordinary neoteny of synaptic spines in the human prefrontal cortex","volume":"108","author":"Z Petanjek","year":"2011","journal-title":"Proc Natl Acad Sci USA."},{"key":"pbio.3003277.ref136","unstructured":"Huttenlocher PR. Synaptogenesis, synapse elimination, and neural plasticity in human cerebral cortex. Threats to optimal development. Routledge; 2013. p. 35\u201354."},{"issue":"6","key":"pbio.3003277.ref137","article-title":"Morphometric brain organization across the human lifespan reveals increased dispersion linked to cognitive performance","volume":"22","author":"J Li","year":"2024","journal-title":"PLoS Biol."},{"key":"pbio.3003277.ref138","article-title":"Functional connectome through the human life span","author":"L Sun","year":"2024","journal-title":"Biorxiv."},{"issue":"4","key":"pbio.3003277.ref139","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1038\/s41593-023-01282-y","article-title":"Intrinsic activity development unfolds along a sensorimotor\u2013association cortical axis in youth","volume":"26","author":"VJ Sydnor","year":"2023","journal-title":"Nat Neurosci."},{"issue":"2","key":"pbio.3003277.ref140","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1161\/01.STR.15.2.221","article-title":"The pathogenesis of watershed infarcts in the brain.","volume":"15","author":"A Torvik","year":"1984","journal-title":"Stroke."},{"issue":"7","key":"pbio.3003277.ref141","doi-asserted-by":"crossref","DOI":"10.1111\/psyp.13796","article-title":"Age-related changes in cerebrovascular health and their effects on neural function and cognition: a comprehensive review","volume":"58","author":"B Zimmerman","year":"2021","journal-title":"Psychophysiology."},{"key":"pbio.3003277.ref142","unstructured":"Faria AV. Annotated clinical MRIs, linked metadata of patients with acute stroke, Baltimore and Maryland 2009 -2019. 2022."},{"issue":"1","key":"pbio.3003277.ref143","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/s41597-022-01923-0","article-title":"Digital 3D brain MRI arterial territories Atlas","volume":"10","author":"C-F Liu","year":"2023","journal-title":"Sci Data."},{"key":"pbio.3003277.ref144","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2004.05.018","article-title":"Partial least squares analysis of neuroimaging data: applications and advances","volume":"23","author":"AR McIntosh","year":"2004","journal-title":"NeuroImage."},{"issue":"1","key":"pbio.3003277.ref145","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1146\/annurev-psych-113011-143804","article-title":"Multivariate statistical analyses for neuroimaging data","volume":"64","author":"AR McIntosh","year":"2013","journal-title":"Annu Rev Psychol."},{"issue":"5","key":"pbio.3003277.ref146","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1093\/brain\/113.5.1395","article-title":"Cerebral blood flow in progressive aphasia without dementia: case report, using 133xenon inhalation, technetium 99m hexamethylpropyleneamine oxime and single photon emission computerized tomography","volume":"113","author":"F Delecluse","year":"1990","journal-title":"Brain."},{"issue":"6","key":"pbio.3003277.ref147","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1002\/ana.20493","article-title":"Cerebral hypoperfusion and clinical onset of dementia: the Rotterdam study","volume":"57","author":"A Ruitenberg","year":"2005","journal-title":"Annals Neurol."},{"issue":"49","key":"pbio.3003277.ref148","doi-asserted-by":"crossref","first-page":"18727","DOI":"10.1073\/pnas.0606298103","article-title":"Hypoxia facilitates Alzheimer\u2019s disease pathogenesis by up-regulating BACE1 gene expression","volume":"103","author":"X Sun","year":"2006","journal-title":"Proc Natl Acad Sci USA."},{"issue":"3","key":"pbio.3003277.ref149","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s00401-010-0718-6","article-title":"The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia","volume":"120","author":"C Iadecola","year":"2010","journal-title":"Acta Neuropathol."},{"issue":"5","key":"pbio.3003277.ref150","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/j.bbadis.2015.12.016","article-title":"Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer\u2019s disease","volume":"1862","author":"AR Nelson","year":"2016","journal-title":"Biochim Biophys Acta (BBA) \u2013 Molecul Basis Disease."},{"issue":"1","key":"pbio.3003277.ref151","first-page":"1","article-title":"The contribution of vascular risk factors in neurodegenerative disorders: from mild cognitive impairment to Alzheimer\u2019s disease","volume":"12","author":"Y-W Cheng","year":"2020","journal-title":"Alz Res Therapy."},{"issue":"10","key":"pbio.3003277.ref152","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1038\/s41593-018-0234-x","article-title":"The role of brain vasculature in neurodegenerative disorders","volume":"21","author":"MD Sweeney","year":"2018","journal-title":"Nat Neurosci."},{"issue":"9","key":"pbio.3003277.ref153","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/s41582-023-00846-7","article-title":"Limbic-predominant age-related TDP43 encephalopathy (LATE) neuropathological change in neurodegenerative diseases","volume":"19","author":"S Nag","year":"2023","journal-title":"Nat Rev Neurol."},{"issue":"11","key":"pbio.3003277.ref154","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1001\/archneur.55.11.1475","article-title":"Impaired clearance of emboli (washout) is an important link between hypoperfusion, embolism, and ischemic stroke","volume":"55","author":"LR Caplan","year":"1998","journal-title":"Arch Neurol."},{"issue":"2","key":"pbio.3003277.ref155","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1254\/jphs.09R02CP","article-title":"\u03b2-Amyloid accumulation in neurovascular units following brain embolism","volume":"111","author":"F Han","year":"2009","journal-title":"J Pharmacol Sci."},{"issue":"3","key":"pbio.3003277.ref156","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1161\/01.STR.0000202590.75972.39","article-title":"Internal and cortical border-zone infarction: clinical and diffusion-weighted imaging features","volume":"37","author":"SW Yong","year":"2006","journal-title":"Stroke."},{"issue":"1","key":"pbio.3003277.ref157","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1365-2990.2010.01139.x","article-title":"Review: cerebral microvascular pathology in ageing and neurodegeneration","volume":"37","author":"WR Brown","year":"2011","journal-title":"Neuropathol Appl Neurobio."},{"issue":"7","key":"pbio.3003277.ref158","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1161\/STROKEAHA.114.008194","article-title":"Selective vulnerability of cortical border zone to microembolic infarct","volume":"46","author":"M Bergui","year":"2015","journal-title":"Stroke."},{"issue":"11","key":"pbio.3003277.ref159","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1136\/jnnp-2016-314978","article-title":"Patterns of atrophy in pathologically confirmed dementias: a voxelwise analysis","volume":"88","author":"L Harper","year":"2017","journal-title":"J Neurol Neurosurg Psychiatry."},{"key":"pbio.3003277.ref160","article-title":"Microsurgical neurovascular anatomy of the brain: the posterior circulation (part II)","volume":"92","author":"AG Lucifero","year":"2021","journal-title":"Acta Bio Medica: Atenei Parmensis."},{"key":"pbio.3003277.ref161","first-page":"308","article-title":"Altered cerebral blood flow covariance network in schizophrenia","volume":"10","author":"F Liu","year":"2016","journal-title":"Front Neurosci."},{"issue":"3","key":"pbio.3003277.ref162","article-title":"Associations of cerebral blood flow patterns with gray and white matter structure in patients with temporal lobe epilepsy","volume":"103","author":"A Ngo","year":"2024","journal-title":"Neurology."},{"issue":"11","key":"pbio.3003277.ref163","doi-asserted-by":"crossref","first-page":"963","DOI":"10.3390\/diagnostics10110963","article-title":"Consistent cerebral blood flow covariance networks across healthy individuals and their similarity with resting state networks and vascular territories","volume":"10","author":"A Pirastru","year":"2020","journal-title":"Diagnostics."},{"issue":"8","key":"pbio.3003277.ref164","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1038\/nmeth.1635","article-title":"Large-scale automated synthesis of human functional neuroimaging data","volume":"8","author":"T Yarkoni","year":"2011","journal-title":"Nat Methods."},{"key":"pbio.3003277.ref165","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3389\/fninf.2011.00017","article-title":"The cognitive atlas: toward a knowledge foundation for cognitive neuroscience","volume":"5","author":"RA Poldrack","year":"2011","journal-title":"Front Neuroinform."},{"issue":"3","key":"pbio.3003277.ref166","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1016\/j.neuroimage.2011.09.017","article-title":"Activation likelihood estimation meta-analysis revisited","volume":"59","author":"SB Eickhoff","year":"2012","journal-title":"NeuroImage."},{"issue":"11","key":"pbio.3003277.ref167","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1212\/WNL.0000000000000780","article-title":"A systematic study of topographical memory and posterior cerebral artery infarctions","volume":"83","author":"T Busigny","year":"2014","journal-title":"Neurology."},{"issue":"2","key":"pbio.3003277.ref168","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/0278-2626(91)90024-3","article-title":"Visual imagery and knowledge about the visual appearance of objects in patients with posterior cerebral artery lesions","volume":"15","author":"G Goldenberg","year":"1991","journal-title":"Brain and Cognition."},{"issue":"18","key":"pbio.3003277.ref169","doi-asserted-by":"crossref","first-page":"5854","DOI":"10.1523\/JNEUROSCI.5192-08.2009","article-title":"The anatomy of object recognition\u2014visual form agnosia caused by medial occipitotemporal stroke","volume":"29","author":"H-O Karnath","year":"2009","journal-title":"J Neurosci."},{"issue":"11","key":"pbio.3003277.ref170","doi-asserted-by":"crossref","first-page":"2138","DOI":"10.1016\/j.apmr.2005.07.289","article-title":"Clinical characteristics and rehabilitation outcomes of patients with posterior cerebral artery stroke","volume":"86","author":"YS Ng","year":"2005","journal-title":"Archiv Phys Med Rehabilit."},{"issue":"1","key":"pbio.3003277.ref171","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0030433","article-title":"Visual agnosia and posterior cerebral artery infarcts: an anatomical-clinical study","volume":"7","author":"O Martinaud","year":"2012","journal-title":"PLoS One."},{"issue":"1","key":"pbio.3003277.ref172","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1212\/WNL.48.1.165","article-title":"Specific semantic memory loss after hypoxic-ischemic injury","volume":"48","author":"MP Alexander","year":"1997","journal-title":"Neurology."},{"issue":"4","key":"pbio.3003277.ref173","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1093\/brain\/awp013","article-title":"Posterior cerebral artery infarcts and semantic category dissociations: a study of 28 patients","volume":"132","author":"E Capitani","year":"2009","journal-title":"Brain."},{"issue":"24","key":"pbio.3003277.ref174","doi-asserted-by":"crossref","first-page":"2386","DOI":"10.1212\/01.wnl.0000314686.94007.d0","article-title":"Anterior cerebral artery infarction: stroke mechanism and clinical-imaging study in 100 patients","volume":"70","author":"SY Kang","year":"2008","journal-title":"Neurology."},{"key":"pbio.3003277.ref175","unstructured":"Wolff CB. Oxygen transport to tissue XXVIII. Springer; 2008. p. 169\u201382."},{"issue":"2","key":"pbio.3003277.ref176","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/aja.1000010204","article-title":"The development of the arm in man","volume":"1","author":"WH Lewis","year":"1902","journal-title":"Am J Anat."},{"key":"pbio.3003277.ref177","doi-asserted-by":"crossref","DOI":"10.3389\/fnint.2022.818685","article-title":"From a demand-based to a supply-limited framework of brain metabolism","volume":"16","author":"S Herculano-Houzel","year":"2022","journal-title":"Front Integr Neurosci."},{"issue":"6","key":"pbio.3003277.ref178","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.1002\/hbm.22768","article-title":"The effect of ageing on fMRI: correction for the confounding effects of vascular reactivity evaluated by joint fMRI and MEG in 335 adults","volume":"36","author":"KA Tsvetanov","year":"2015","journal-title":"Human Brain Mapping."},{"issue":"1815","key":"pbio.3003277.ref179","doi-asserted-by":"crossref","first-page":"20190631","DOI":"10.1098\/rstb.2019.0631","article-title":"Separating vascular and neuronal effects of age on fMRI BOLD signals","volume":"376","author":"KA Tsvetanov","year":"2021","journal-title":"Philos Trans R Soc B."},{"issue":"7","key":"pbio.3003277.ref180","doi-asserted-by":"crossref","DOI":"10.1111\/psyp.13714","article-title":"The effects of age on resting-state BOLD signal variability is explained by cardiovascular and cerebrovascular factors","volume":"58","author":"KA Tsvetanov","year":"2021","journal-title":"Psychophysiology."},{"issue":"11","key":"pbio.3003277.ref181","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1242\/jeb.017574","article-title":"Energy limitation as a selective pressure on the evolution of sensory systems","volume":"211","author":"JE Niven","year":"2008","journal-title":"J Exp Biol."},{"issue":"5","key":"pbio.3003277.ref182","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1111\/j.1460-9568.1994.tb00984.x","article-title":"Modular organization of human extrastriate visual cortex: evidence from cytochrome oxidase pattern in normal and macular degeneration cases","volume":"6","author":"S Clarke","year":"1994","journal-title":"Eur J Neurosci."},{"issue":"6","key":"pbio.3003277.ref183","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1017\/S0952523803206088","article-title":"Complete flatmounting of the macaque cerebral cortex","volume":"20","author":"LC SINCICH","year":"2003","journal-title":"Vis Neurosci."},{"issue":"3","key":"pbio.3003277.ref184","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1046\/j.1460-9568.1999.00518.x","article-title":"Dorsolateral prefrontal cortex: comparative cytoarchitectonic analysis in the human and the macaque brain and corticocortical connection patterns","volume":"11","author":"M Petrides","year":"1999","journal-title":"Eur J Neurosci."},{"issue":"3","key":"pbio.3003277.ref185","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.mvr.2009.01.007","article-title":"The pericyte: cellular regulator of microvascular blood flow","volume":"77","author":"ME Kutcher","year":"2009","journal-title":"Microvascul Res."},{"issue":"7494","key":"pbio.3003277.ref186","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/nature13165","article-title":"Capillary pericytes regulate cerebral blood flow in health and disease","volume":"508","author":"CN Hall","year":"2014","journal-title":"Nature."},{"issue":"11","key":"pbio.3003277.ref187","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1016\/j.ajpath.2021.02.023","article-title":"Endothelial control of cerebral blood flow","volume":"191","author":"JW Ashby","year":"2021","journal-title":"Am J Pathol."},{"issue":"8","key":"pbio.3003277.ref188","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1038\/jcbfm.2014.104","article-title":"Highly energized inhibitory interneurons are a central element for information processing in cortical networks","volume":"34","author":"O Kann","year":"2014","journal-title":"J Cereb Blood Flow Metab."},{"issue":"3","key":"pbio.3003277.ref189","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/BF00310651","article-title":"Coupling of function, metabolism, and blood flow in the brain","volume":"14","author":"W Kuschinsky","year":"1991","journal-title":"Neurosurg Rev."},{"issue":"1","key":"pbio.3003277.ref190","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.neuron.2024.12.014","article-title":"The pathobiology of neurovascular aging","volume":"113","author":"MM Santisteban","year":"2025","journal-title":"Neuron."},{"issue":"4","key":"pbio.3003277.ref191","doi-asserted-by":"crossref","DOI":"10.1152\/ajpheart.1980.238.4.H449","article-title":"Cerebral circulatory and metabolic effects of vasoactive intestinal polypeptide","volume":"238","author":"J McCulloch","year":"1980","journal-title":"Am J Physiol-Heart Circul Physiol."},{"issue":"3","key":"pbio.3003277.ref192","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0014-2999(82)90041-3","article-title":"Vasoactive intestinal peptide as a neurotransmitter in the cerebral circulation","volume":"78","author":"SP Duckles","year":"1982","journal-title":"Eur J Pharmacol."},{"issue":"2","key":"pbio.3003277.ref193","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/0196-9781(84)90229-8","article-title":"Distribution and dilatory effect of vasoactive intestinal polypeptide (VIP) in human cerebral arteries","volume":"5","author":"L Edvinsson","year":"1984","journal-title":"Peptides."},{"key":"pbio.3003277.ref194","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/0166-2236(85)90050-5","article-title":"Functional role of perivascular peptides in the control of cerebral circulation","volume":"8","author":"L Edvinsson","year":"1985","journal-title":"Trends Neurosci."},{"key":"pbio.3003277.ref195","doi-asserted-by":"crossref","unstructured":"Wahl M, Schilling L. Regulation of cerebral blood flow\u2014a brief review. 1993.","DOI":"10.1007\/978-3-7091-9302-0_1"},{"issue":"6","key":"pbio.3003277.ref196","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1056\/NEJM199508103330607","article-title":"Endothelins","volume":"333","author":"ER Levin","year":"1995","journal-title":"New Engl J Med."},{"issue":"2","key":"pbio.3003277.ref197","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1097\/00006123-199702000-00023","article-title":"Presence of contractile Endothelin-A and dilatory Endothelin-B receptors in human cerebral arteries","volume":"40","author":"T Nilsson","year":"1997","journal-title":"Neurosurgery."},{"issue":"11","key":"pbio.3003277.ref198","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1046\/j.1440-1681.1999.03151.x","article-title":"The \u2018ABC\u2019 of GABA receptors: a brief review","volume":"26","author":"M Chebib","year":"1999","journal-title":"Clin Exp Pharmacol Physiol."},{"issue":"2","key":"pbio.3003277.ref199","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0022-510X(98)00288-3","article-title":"Gender-related effects of indomethacin on cerebrovascular CO2 reactivity","volume":"162","author":"A Kastrup","year":"1999","journal-title":"J Neurologic Sci."},{"issue":"5","key":"pbio.3003277.ref200","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1210\/er.2001-0045","article-title":"Estrogen modulation of endothelial nitric oxide synthase","volume":"23","author":"KL Chambliss","year":"2002","journal-title":"Endocrine Rev."},{"issue":"2","key":"pbio.3003277.ref201","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1006\/exnr.1993.1095","article-title":"Microvascular density of the human paraventricular nucleus decreases with aging but not hypertension","volume":"121","author":"WB Abernethy","year":"1993","journal-title":"Exp Neurol."},{"issue":"8","key":"pbio.3003277.ref202","doi-asserted-by":"crossref","first-page":"3515","DOI":"10.1210\/endo.138.8.5330","article-title":"Decreases in cerebral microvasculature with age are associated with the decline in growth hormone and insulin-like growth factor 1*","volume":"138","author":"WE Sonntag","year":"1997","journal-title":"Endocrinology."},{"issue":"6","key":"pbio.3003277.ref203","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/S0301-0082(00)00068-X","article-title":"Cerebral microvascular pathology in aging and Alzheimer\u2019s disease","volume":"64","author":"E Farkas","year":"2001","journal-title":"Prog Neurobiol."},{"issue":"5","key":"pbio.3003277.ref204","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1161\/STROKEAHA.108.535245","article-title":"Carotid artery atherosclerosis, MRI indices of brain ischemia, aging, and cognitive impairment","volume":"40","author":"JR Romero","year":"2009","journal-title":"Stroke."},{"issue":"3","key":"pbio.3003277.ref205","doi-asserted-by":"crossref","first-page":"813","DOI":"10.3233\/JAD-2010-100081","article-title":"Cardiac output as a potential risk factor for abnormal brain aging","volume":"20","author":"AL Jefferson","year":"2010","journal-title":"JAD."},{"issue":"5","key":"pbio.3003277.ref206","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1111\/jnc.14234","article-title":"Cerebral blood flow in normal aging adults: cardiovascular determinants, clinical implications, and aerobic fitness","volume":"144","author":"T Tarumi","year":"2017","journal-title":"J Neurochem."},{"issue":"1","key":"pbio.3003277.ref207","doi-asserted-by":"crossref","first-page":"6398","DOI":"10.1038\/s41467-024-50559-8","article-title":"Aging drives cerebrovascular network remodeling and functional changes in the mouse brain","volume":"15","author":"HC Bennett","year":"2024","journal-title":"Nat Commun."},{"issue":"4","key":"pbio.3003277.ref208","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1017\/S031716710003095X","article-title":"The mechanism of embolic watershed infarction: experimental studies","volume":"17","author":"MS Pollanen","year":"1990","journal-title":"Can J Neurol Sci."},{"issue":"7","key":"pbio.3003277.ref209","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1002\/oby.20170","article-title":"Low cerebral blood flow is associated with lower memory function in metabolic syndrome","volume":"21","author":"AC Birdsill","year":"2013","journal-title":"Obesity."},{"issue":"6","key":"pbio.3003277.ref210","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.1177\/0271678X16663214","article-title":"Insulin resistance is associated with lower arterial blood flow and reduced cortical perfusion in cognitively asymptomatic middle-aged adults","volume":"37","author":"SM Hoscheidt","year":"2016","journal-title":"J Cereb Blood Flow Metab."},{"key":"pbio.3003277.ref211","doi-asserted-by":"crossref","first-page":"56","DOI":"10.2337\/diab.32.2.S56","article-title":"The effect of diabetes on blood flow properties","volume":"32","author":"DE McMillan","year":"1983","journal-title":"Diabetes."},{"issue":"11","key":"pbio.3003277.ref212","doi-asserted-by":"crossref","first-page":"2601","DOI":"10.1172\/JCI118709","article-title":"Obesity\/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance.","volume":"97","author":"HO Steinberg","year":"1996","journal-title":"J Clin Invest."},{"issue":"1","key":"pbio.3003277.ref213","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1210\/edrv.22.1.0417","article-title":"Diabetes and endothelial dysfunction: a clinical perspective","volume":"22","author":"J Calles-Escandon","year":"2001","journal-title":"Endocrine Rev."},{"issue":"1","key":"pbio.3003277.ref214","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1749-6632.2012.06480.x","article-title":"LDL-cholesterol versus HDL-cholesterol in the atherosclerotic plaque: inflammatory resolution versus thrombotic chaos","volume":"1254","author":"L Badimon","year":"2012","journal-title":"Annals New York Acad Sci."},{"issue":"10","key":"pbio.3003277.ref215","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1161\/CIRCRESAHA.119.312617","article-title":"HDL and reverse cholesterol transport: basic mechanisms and their roles in vascular health and disease","volume":"124","author":"M Ouimet","year":"2019","journal-title":"Circulat Res."},{"issue":"1","key":"pbio.3003277.ref216","doi-asserted-by":"crossref","first-page":"11934","DOI":"10.1038\/ncomms11934","article-title":"Early role of vascular dysregulation on late-onset Alzheimer\u2019s disease based on multifactorial data-driven analysis","volume":"7","author":"Y Iturria-Medina","year":"2016","journal-title":"Nat Commun."},{"key":"pbio.3003277.ref217","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jns.2012.07.066","article-title":"Late and early onset dementia: what is the role of vascular factors? A retrospective study","volume":"322","author":"A Carotenuto","year":"2012","journal-title":"J Neurol Sci."},{"key":"pbio.3003277.ref218","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.ejphar.2015.05.022","article-title":"New cardiovascular targets to prevent late onset Alzheimer disease","volume":"763","author":"JAHR Claassen","year":"2015","journal-title":"Eur J Pharmacol."},{"issue":"3","key":"pbio.3003277.ref219","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.3233\/JAD-170367","article-title":"Low prevalence and clinical effect of vascular risk factors in early-onset Alzheimer\u2019s disease","volume":"60","author":"Y Chen","year":"2017","journal-title":"JAD."},{"key":"pbio.3003277.ref220","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.brainres.2013.08.007","article-title":"Chronic cerebral ischemia induces redistribution and abnormal phosphorylation of transactivation-responsive DNA-binding protein-43 in mice","volume":"1533","author":"A Shindo","year":"2013","journal-title":"Brain Res."},{"issue":"2","key":"pbio.3003277.ref221","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1007\/s13311-021-01015-8","article-title":"Targeting TDP-43 pathology alleviates cognitive and motor deficits caused by chronic cerebral hypoperfusion","volume":"18","author":"SS Thammisetty","year":"2021","journal-title":"Neurotherapeutics."},{"issue":"11","key":"pbio.3003277.ref222","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1003956","article-title":"Epidemic spreading model to characterize misfolded proteins propagation in aging and associated neurodegenerative disorders","volume":"10","author":"Y Iturria-Medina","year":"2014","journal-title":"PLoS Comput Biol."},{"issue":"8","key":"pbio.3003277.ref223","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.acra.2006.05.009","article-title":"Analysis of ischemic stroke MR images by means of brain atlases of anatomy and blood supply territories","volume":"13","author":"WL Nowinski","year":"2006","journal-title":"Acad Radiol."},{"issue":"6","key":"pbio.3003277.ref224","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1161\/STROKEAHA.106.477000","article-title":"Digital map of posterior cerebral artery infarcts associated with posterior cerebral artery trunk and branch occlusion","volume":"38","author":"MBBS Phan","year":"2007","journal-title":"Stroke."},{"issue":"6","key":"pbio.3003277.ref225","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1159\/000214215","article-title":"Digital probabilistic Atlas of the border region between the middle and posterior cerebral arteries","volume":"27","author":"TG Phan","year":"2009","journal-title":"Cerebrovasc Dis."},{"issue":"1","key":"pbio.3003277.ref226","doi-asserted-by":"crossref","first-page":"11708","DOI":"10.1038\/s41598-019-48266-2","article-title":"Supratentorial cerebral arterial territories for computed tomograms: a mapping study in 1160 large artery infarcts","volume":"9","author":"D-E Kim","year":"2019","journal-title":"Sci Rep."},{"issue":"1","key":"pbio.3003277.ref227","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1001\/jamaneurol.2018.2808","article-title":"Mapping the supratentorial cerebral arterial territories using 1160 large artery infarcts","volume":"76","author":"D-E Kim","year":"2019","journal-title":"JAMA Neurol."},{"issue":"3","key":"pbio.3003277.ref228","doi-asserted-by":"crossref","first-page":"110","DOI":"10.3121\/cmr.2021.1632","article-title":"Where in the brain do strokes occur? A pilot study and call for data","volume":"19","author":"L Nichols","year":"2021","journal-title":"Clin Med Res."},{"key":"pbio.3003277.ref229","unstructured":"Nogles TE, Galuska MA. Middle cerebral artery stroke. StatPearls. StatPearls Publishing; 2023."},{"issue":"3","key":"pbio.3003277.ref230","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1161\/CIRCRESAHA.116.308398","article-title":"Stroke risk factors, genetics, and prevention","volume":"120","author":"AK Boehme","year":"2017","journal-title":"Circulat Res."},{"issue":"7","key":"pbio.3003277.ref231","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/S1474-4422(16)00102-2","article-title":"Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies","volume":"15","author":"G Chauhan","year":"2016","journal-title":"Lancet Neurol."},{"issue":"2","key":"pbio.3003277.ref232","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/S1474-4422(15)00338-5","article-title":"Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study","volume":"15","author":"SL Pulit","year":"2016","journal-title":"Lancet Neurol."},{"issue":"4","key":"pbio.3003277.ref233","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1016\/j.neuroimage.2004.07.057","article-title":"Probabilistic map of blood flow distribution in the brain from the internal carotid artery","volume":"23","author":"JS Lee","year":"2004","journal-title":"NeuroImage."},{"issue":"4","key":"pbio.3003277.ref234","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1161\/01.STR.0000120312.26163.EC","article-title":"Flow territory mapping of the cerebral arteries with regional perfusion MRI","volume":"35","author":"J Hendrikse","year":"2004","journal-title":"Stroke."},{"issue":"1","key":"pbio.3003277.ref235","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.neuroimage.2005.07.011","article-title":"In vivo flow territory mapping of major brain feeding arteries","volume":"29","author":"PJ van Laar","year":"2006","journal-title":"NeuroImage."},{"issue":"3","key":"pbio.3003277.ref236","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1002\/jmri.21462","article-title":"Mapping of vertebral artery perfusion territories using arterial spin labeling MRI","volume":"28","author":"AP Kansagra","year":"2008","journal-title":"Magnet Resonance Imaging."},{"issue":"12","key":"pbio.3003277.ref237","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1038\/s41583-023-00752-3","article-title":"Towards a biologically annotated brain connectome","volume":"24","author":"V Bazinet","year":"2023","journal-title":"Nat Rev Neurosci."},{"key":"pbio.3003277.ref238","doi-asserted-by":"crossref","unstructured":"Phellan R, Peixinho A, Falc\u00e3o A, Forkert ND. Vascular segmentation in TOF MRA images of the brain using a deep convolutional neural network. In: Intravascular Imaging, Computer Assisted Stenting,, Large-Scale Annotation of Biomedical Data, Expert Label Synthesis: 6th Joint International Workshops and CVII-STENT 2017 and Second International Workshop, LABELS 2017, Held in Conjunction with MICCAI 2017, Qu\u00e9bec City, QC, Canada, September 10\u201314, 2017, Proceedings 2, 2017. p. 39\u201346.","DOI":"10.1007\/978-3-319-67534-3_5"},{"key":"pbio.3003277.ref239","doi-asserted-by":"crossref","first-page":"104254","DOI":"10.1016\/j.compbiomed.2021.104254","article-title":"Synthesizing anonymized and labeled TOF-MRA patches for brain vessel segmentation using generative adversarial networks","volume":"131","author":"T Kossen","year":"2021","journal-title":"Comput Biol Med."},{"key":"pbio.3003277.ref240","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.71186","article-title":"Imaging of the pial arterial vasculature of the human brain in vivo using high-resolution 7T time-of-flight angiography","volume":"11","author":"S Bollmann","year":"2022","journal-title":"eLife."},{"key":"pbio.3003277.ref241","article-title":"Arterial spin labelling perfusion MRI analysis for the human connectome project lifespan ageing and development studies","volume":"3","author":"TF Kirk","year":"2025","journal-title":"Imaging Neurosci."},{"key":"pbio.3003277.ref242","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.neuroimage.2013.04.127","article-title":"The minimal preprocessing pipelines for the human connectome project","volume":"80","author":"MF Glasser","year":"2013","journal-title":"NeuroImage."},{"key":"pbio.3003277.ref243","doi-asserted-by":"crossref","first-page":"1104508","DOI":"10.3389\/fninf.2023.1104508","article-title":"QuNex\u2014an integrative platform for reproducible neuroimaging analytics","volume":"17","author":"JL Ji","year":"2023","journal-title":"Front Neuroinform."},{"issue":"3","key":"pbio.3003277.ref244","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1002\/mrm.27499","article-title":"A framework for motion correction of background suppressed arterial spin labeling perfusion images acquired with simultaneous multi-slice EPI","volume":"81","author":"Y Suzuki","year":"2018","journal-title":"Magnetic Resonance Med."},{"key":"pbio.3003277.ref245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1162\/imag_a_00041","article-title":"BASIL: a toolbox for perfusion quantification using arterial spin labelling","volume":"1","author":"MA Chappell","year":"2023","journal-title":"Imaging Neurosci."},{"issue":"3","key":"pbio.3003277.ref246","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1002\/mrm.1910400308","article-title":"A general kinetic model for quantitative perfusion imaging with arterial spin labeling","volume":"40","author":"RB Buxton","year":"1998","journal-title":"Magnet Resonance Med."},{"issue":"4","key":"pbio.3003277.ref247","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1002\/mrm.22641","article-title":"Partial volume correction of multiple inversion time arterial spin labeling MRI data","volume":"65","author":"MA Chappell","year":"2011","journal-title":"Magnet Resonance Med."},{"issue":"4","key":"pbio.3003277.ref248","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1002\/mrm.28000","article-title":"Calibration of arterial spin labeling data\u2014potential pitfalls in post-processing","volume":"83","author":"J Pinto","year":"2020","journal-title":"Magnetic Resonance Med."},{"issue":"2","key":"pbio.3003277.ref249","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.neuroimage.2012.01.021","article-title":"FreeSurfer","volume":"62","author":"B Fischl","year":"2012","journal-title":"Neuroimage."},{"issue":"5","key":"pbio.3003277.ref250","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1109\/TMI.2019.2951080","article-title":"Toblerone: surface-based partial volume estimation","volume":"39","author":"TF Kirk","year":"2020","journal-title":"IEEE Trans Med Imaging."},{"key":"pbio.3003277.ref251","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.neuroimage.2014.05.069","article-title":"MSM: a new flexible framework for Multimodal Surface Matching","volume":"100","author":"EC Robinson","year":"2014","journal-title":"NeuroImage."},{"key":"pbio.3003277.ref252","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.neuroimage.2017.10.037","article-title":"Multimodal surface matching with higher-order smoothness constraints","volume":"167","author":"EC Robinson","year":"2018","journal-title":"NeuroImage."},{"key":"pbio.3003277.ref253","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.72129","article-title":"Standardizing workflows in imaging transcriptomics with the abagen toolbox","volume":"10","author":"RD Markello","year":"2021","journal-title":"eLife."},{"issue":"1","key":"pbio.3003277.ref254","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1038\/jcbfm.2009.195","article-title":"Kinetic modeling of the serotonin 5-HT1B receptor radioligand [11C]P943 in humans","volume":"30","author":"J-D Gallezot","year":"2009","journal-title":"J Cereb Blood Flow Metab."},{"key":"pbio.3003277.ref255","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/s00213-010-1881-0","article-title":"Reduced ventral striatal\/ventral pallidal serotonin1B receptor binding potential in major depressive disorder","volume":"213","author":"JW Murrough","year":"2010","journal-title":"Psychopharmacology."},{"issue":"9","key":"pbio.3003277.ref256","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1001\/archgenpsychiatry.2011.91","article-title":"The effect of early trauma exposure on serotonin type 1B receptor expression revealed by reduced selective radioligand binding","volume":"68","author":"JW Murrough","year":"2011","journal-title":"Arch Gen Psychiatry."},{"issue":"10","key":"pbio.3003277.ref257","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.biopsych.2013.11.022","article-title":"Reductions in brain 5-HT1B receptor availability in primarily cocaine-dependent humans","volume":"76","author":"D Matuskey","year":"2014","journal-title":"Biol Psychiatry."},{"key":"pbio.3003277.ref258","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.jad.2016.02.021","article-title":"OCD is associated with an altered association between sensorimotor gating and cortical and subcortical 5-HT1b receptor binding","volume":"196","author":"C Pittenger","year":"2016","journal-title":"J Affect Disord."},{"issue":"3","key":"pbio.3003277.ref259","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1007\/s00259-014-2958-5","article-title":"Test\u2013retest reliability of the novel 5-HT1B receptor PET radioligand [11C]P943","volume":"42","author":"A Saricicek","year":"2014","journal-title":"Eur J Nucl Med Mol Imaging."},{"issue":"10","key":"pbio.3003277.ref260","doi-asserted-by":"crossref","DOI":"10.1002\/syn.22159","article-title":"Inverse changes in raphe and cortical 5-HT1B receptor availability after acute tryptophan depletion in healthy human subjects","volume":"74","author":"SR Baldassarri","year":"2020","journal-title":"Synapse."},{"issue":"9","key":"pbio.3003277.ref261","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.2967\/jnumed.117.206516","article-title":"Age-related change in 5-HT6 receptor availability in healthy male Volunteers measured with 11C-GSK215083 PET","volume":"59","author":"R Radhakrishnan","year":"2018","journal-title":"J Nucl Med."},{"key":"pbio.3003277.ref262","doi-asserted-by":"crossref","first-page":"111007","DOI":"10.1016\/j.pscychresns.2019.111007","article-title":"In vivo 5-HT6 and 5-HT2A receptor availability in antipsychotic treated schizophrenia patients vs. unmedicated healthy humans measured with [11C]GSK215083 PET","volume":"295","author":"R Radhakrishnan","year":"2020","journal-title":"Psychiatry Res: Neuroimag."},{"key":"pbio.3003277.ref263","article-title":"In vivo NMDA receptor function in people with NMDA receptor antibody encephalitis","author":"M Galovic","year":"2021","journal-title":"medRxiv."},{"key":"pbio.3003277.ref264","doi-asserted-by":"crossref","first-page":"118194","DOI":"10.1016\/j.neuroimage.2021.118194","article-title":"Validation of a combined image derived input function and venous sampling approach for the quantification of [18F]GE-179 PET binding in the brain","volume":"237","author":"M Galovic","year":"2021","journal-title":"NeuroImage."},{"issue":"3","key":"pbio.3003277.ref265","doi-asserted-by":"crossref","first-page":"423","DOI":"10.2967\/jnumed.113.130641","article-title":"Initial evaluation of 18F-GE-179, a putative PET tracer for activated N-methyl d-aspartate receptors","volume":"55","author":"CJ McGinnity","year":"2014","journal-title":"J Nucl Med."},{"key":"pbio.3003277.ref266","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.neuroimage.2017.12.060","article-title":"Structural covariance networks are coupled to expression of genes enriched in supragranular layers of the human cortex","volume":"171","author":"R Romero-Garcia","year":"2018","journal-title":"NeuroImage."},{"issue":"8","key":"pbio.3003277.ref267","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1038\/s41583-022-00601-9","article-title":"Null models in network neuroscience","volume":"23","author":"F V\u00e1\u0161a","year":"2022","journal-title":"Nat Rev Neurosci."},{"issue":"10","key":"pbio.3003277.ref268","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1093\/cercor\/bhr291","article-title":"Parcellations and hemispheric asymmetries of human cerebral cortex analyzed onsurface-based atlases","volume":"22","author":"DC Van Essen","year":"2012","journal-title":"Cerebral Cortex."},{"issue":"2","key":"pbio.3003277.ref269","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s00429-012-0460-z","article-title":"The myeloarchitectonic studies on the human cerebral cortex of the Vogt\u2013Vogt school, and their significance for the interpretation of functional neuroimaging data","volume":"218","author":"R Nieuwenhuys","year":"2012","journal-title":"Brain Struct Funct."},{"key":"pbio.3003277.ref270","unstructured":"Lotter LD, Dukart J, Fulcher BD. ABAnnotate: a toolbox for ensemble-based multimodal gene-category enrichment analysis of human neuroimaging data. 2022. https:\/\/doi.org\/10.5281\/zenodo.6463329"},{"issue":"1","key":"pbio.3003277.ref271","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1093\/cercor\/bhx249","article-title":"Adolescent tuning of association cortex in human structural brain networks","volume":"28","author":"F V\u00e1\u0161a","year":"2017","journal-title":"Cerebral Cortex."},{"key":"pbio.3003277.ref272","first-page":"1","article-title":"Generalized additive models for location scale and shape (GAMLSS) in R","volume":"23","author":"DM Stasinopoulos","year":"2008","journal-title":"J Statist Softw."},{"issue":"1","key":"pbio.3003277.ref273","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/scan\/nsy107","article-title":"Tracking mood fluctuations with functional network patterns","volume":"14","author":"N Mirchi","year":"2018","journal-title":"Soc Cognit Affect Neurosci."},{"issue":"9","key":"pbio.3003277.ref274","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1038\/s41562-021-01082-z","article-title":"Mapping gene transcription and neurocognition across human neocortex","volume":"5","author":"JY Hansen","year":"2021","journal-title":"Nat Hum Behav."},{"issue":"1","key":"pbio.3003277.ref275","doi-asserted-by":"crossref","DOI":"10.1038\/s42003-020-0794-7","article-title":"BrainSpace: a toolbox for the analysis of macroscale gradients in neuroimaging and connectomics datasets","volume":"3","author":"R Vos de Wael","year":"2020","journal-title":"Commun Biol."},{"issue":"2","key":"pbio.3003277.ref276","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1109\/MCSE.2011.37","article-title":"The NumPy array: a structure for efficient numerical computation","volume":"13","author":"S van der Walt","year":"2011","journal-title":"Comput Sci Eng."},{"issue":"7825","key":"pbio.3003277.ref277","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/s41586-020-2649-2","article-title":"Array programming with NumPy","volume":"585","author":"CR Harris","year":"2020","journal-title":"Nature."},{"issue":"3","key":"pbio.3003277.ref278","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1038\/s41592-019-0686-2","article-title":"SciPy 1.0: fundamental algorithms for scientific computing in Python","volume":"17","author":"P Virtanen","year":"2020","journal-title":"Nat Methods."},{"issue":"1","key":"pbio.3003277.ref279","first-page":"51","article-title":"Data structures for statistical computing in Python","volume":"445","author":"W McKinney","year":"2010","journal-title":"SciPy."},{"issue":"60","key":"pbio.3003277.ref280","doi-asserted-by":"crossref","first-page":"3021","DOI":"10.21105\/joss.03021","article-title":"seaborn: statistical data visualization","volume":"6","author":"M Waskom","year":"2021","journal-title":"JOSS."},{"issue":"3","key":"pbio.3003277.ref281","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1109\/MCSE.2007.55","article-title":"Matplotlib: a 2D graphics environment","volume":"9","author":"JD Hunter","year":"2007","journal-title":"Comput Sci Eng."},{"key":"pbio.3003277.ref282","doi-asserted-by":"crossref","unstructured":"Seabold S, Perktold J. Statsmodels: Econometric and statistical modeling with python. In: 9th Python in Science Conference; 2010.","DOI":"10.25080\/Majora-92bf1922-011"},{"issue":"3","key":"pbio.3003277.ref283","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.neuroimage.2009.10.003","article-title":"Complex network measures of brain connectivity: uses and interpretations","volume":"52","author":"M Rubinov","year":"2010","journal-title":"NeuroImage."},{"key":"pbio.3003277.ref284","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3389\/fninf.2014.00014","article-title":"Machine learning for neuroimaging with scikit-learn","volume":"8","author":"A Abraham","year":"2014","journal-title":"Front Neuroinform."},{"key":"pbio.3003277.ref285","unstructured":"Brett M, Markiewicz CJ, Hanke M, Cote MA, Cipollini B, McCarthy P, et al. 2022."},{"key":"pbio.3003277.ref286","doi-asserted-by":"crossref","first-page":"118052","DOI":"10.1016\/j.neuroimage.2021.118052","article-title":"Comparing spatial null models for brain maps","volume":"236","author":"RD Markello","year":"2021","journal-title":"NeuroImage."},{"key":"pbio.3003277.ref287","unstructured":"Gautier L. 2023. rpy2 Release 3.5.17. 2023. https:\/\/github.com\/rpy2\/rpy2\/releases\/tag\/RELEASE_3_5_17"},{"key":"pbio.3003277.ref288","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.neuroimage.2016.04.002","article-title":"The brain analysis library of spatial maps and Atlases (BALSA) database","volume":"144","author":"DC Van Essen","year":"2017","journal-title":"NeuroImage."},{"key":"pbio.3003277.ref289","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.neuroimage.2013.05.077","article-title":"Human connectome project informatics: quality control, database services, and data visualization","volume":"80","author":"DS Marcus","year":"2013","journal-title":"NeuroImage."},{"issue":"9","key":"pbio.3003277.ref290","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1038\/nn.4361","article-title":"The human connectome project\u2019s neuroimaging approach","volume":"19","author":"MF Glasser","year":"2016","journal-title":"Nat Neurosci."},{"issue":"19","key":"pbio.3003277.ref291","doi-asserted-by":"crossref","first-page":"9604","DOI":"10.1073\/pnas.1820754116","article-title":"Cortical patterning of abnormal morphometric similarity in psychosis is associated with brain expression of schizophrenia-related genes","volume":"116","author":"SE Morgan","year":"2019","journal-title":"Proc Natl Acad Sci USA."},{"issue":"23","key":"pbio.3003277.ref292","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2204433119","article-title":"Multiscale neural signatures of major depressive, anxiety, and stress-related disorders","volume":"119","author":"P Zhukovsky","year":"2022","journal-title":"Proc Natl Acad Sci USA."}],"updated-by":[{"DOI":"10.1371\/journal.pbio.3003277","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T00:00:00Z","timestamp":1754352000000}}],"container-title":["PLOS Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pbio.3003277","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T19:39:03Z","timestamp":1754422743000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pbio.3003277"}},"subtitle":[],"editor":[{"given":"Laura D.","family":"Lewis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,7,29]]},"references-count":292,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2025,7,29]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pbio.3003277","relation":{"new_version":[{"id-type":"doi","id":"10.1371\/journal.pbio.3003277","asserted-by":"object"}]},"ISSN":["1545-7885"],"issn-type":[{"value":"1545-7885","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,29]]}}}