{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:29:39Z","timestamp":1779928179636,"version":"3.53.1"},"update-to":[{"DOI":"10.1371\/journal.pcbi.1012903","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000}}],"reference-count":84,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T00:00:00Z","timestamp":1744070400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"crossref","award":["2022R1F1A1064487"],"award-info":[{"award-number":["2022R1F1A1064487"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"crossref","award":["4299990414089"],"award-info":[{"award-number":["4299990414089"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2024-00405375"],"award-info":[{"award-number":["RS-2024-00405375"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.ploscompbiol.org"],"crossmark-restriction":false},"short-container-title":["PLoS Comput Biol"],"abstract":"<jats:p>Infectious diseases have caused significant economic and human losses worldwide. Growing concerns exist regarding climate change potentially exacerbating the spread of these diseases, particularly those transmitted by vectors such as ticks and mosquitoes. Tick-borne diseases, such as Severe Fever with Thrombocytopenia Syndrome (SFTS), can be particularly detrimental to elderly and immunocompromised individuals. This study utilizes a mathematical modeling approach to predict changes in tick populations under climate change scenarios, incorporating tick ecology and climate-sensitive parameters. Sensitivity analysis is performed to investigate the factors influencing tick population dynamics. The study further explores effective tick control strategies and their cost-effectiveness in the context of climate change. The findings indicate that the efficacy of tick population reduction varies greatly depending on the timing of control measure implementation and the effectiveness of the control strategies exhibits a strong dependence on the duration of implementation. Furthermore, as climate change intensifies, tick populations are projected to increase, leading to a rise in control costs and SFTS cases. In light of these findings, identifying and implementing appropriate control measures to manage tick populations under climate change will be increasingly crucial.<\/jats:p>","DOI":"10.1371\/journal.pcbi.1012903","type":"journal-article","created":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T18:38:56Z","timestamp":1744137536000},"page":"e1012903","update-policy":"https:\/\/doi.org\/10.1371\/journal.pcbi.corrections_policy","source":"Crossref","is-referenced-by-count":8,"title":["The impact of climate change on ecology of tick associated with tick-borne diseases"],"prefix":"10.1371","volume":"21","author":[{"given":"Heejin","family":"Choi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3247-5791","authenticated-orcid":true,"given":"Chang Hyeong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,4,8]]},"reference":[{"issue":"7181","key":"pcbi.1012903.ref001","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1038\/nature06536","article-title":"Global trends in emerging infectious diseases","volume":"451","author":"KE Jones","year":"2008","journal-title":"Nature"},{"issue":"1","key":"pcbi.1012903.ref002","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1038\/emi.2013.1","article-title":"A highly pathogenic new bunyavirus emerged in China","volume":"2","author":"D Li","year":"2013","journal-title":"Emerg Microbes Infect"},{"issue":"5","key":"pcbi.1012903.ref003","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1038\/s12276-021-00610-1","article-title":"Severe fever with thrombocytopenia syndrome virus: emerging novel phlebovirus and their control strategy","volume":"53","author":"MA Casel","year":"2021","journal-title":"Exp Mol Med"},{"issue":"9","key":"pcbi.1012903.ref004","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.3390\/microorganisms11092309","article-title":"Emerging tick-borne dabie bandavirus: virology, epidemiology, and prevention","volume":"11","author":"E-H Kim","year":"2023","journal-title":"Microorganisms"},{"issue":"2","key":"pcbi.1012903.ref005","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.ttbdis.2017.09.002","article-title":"Prevalence of antibodies against severe fever with thrombocytopenia syndrome virus in shelter dogs in the Republic of Korea","volume":"9","author":"S-H Lee","year":"2018","journal-title":"Ticks Tick Borne Dis"},{"issue":"10","key":"pcbi.1012903.ref006","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.jiac.2018.06.007","article-title":"Seroprevalence of severe fever with thrombocytopenia syndrome (SFTS) virus antibodies in humans and animals in Ehime prefecture, Japan, an endemic region of SFTS","volume":"24","author":"T Kimura","year":"2018","journal-title":"J Infect Chemother"},{"issue":"3","key":"pcbi.1012903.ref007","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.jcv.2014.03.020","article-title":"Seroprevalence of antibodies against SFTS virus infection in farmers and animals, Jiangsu, China","volume":"60","author":"Z Li","year":"2014","journal-title":"J Clin Virol"},{"issue":"16","key":"pcbi.1012903.ref008","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1056\/NEJMoa1010095","article-title":"Fever with thrombocytopenia associated with a novel bunyavirus in China","volume":"364","author":"X-J Yu","year":"2011","journal-title":"N Engl J Med"},{"issue":"3","key":"pcbi.1012903.ref009","doi-asserted-by":"crossref","first-page":"195","DOI":"10.3961\/jpmph.18.289","article-title":"Epidemiological and clinical characteristics of confirmed cases of severe fever with thrombocytopenia syndrome in Jeju Province, Korea, 2014-2018","volume":"52","author":"J Kim","year":"2019","journal-title":"J Prev Med Public Health"},{"issue":"11","key":"pcbi.1012903.ref010","first-page":"1892","article-title":"Severe fever with thrombocytopenia syndrome, South Korea, 2012","volume":"19","author":"K Kim","year":"2013","journal-title":"Emerg Infect Dis."},{"key":"pcbi.1012903.ref011"},{"issue":"4","key":"pcbi.1012903.ref012","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.ijpara.2004.12.013","article-title":"A dynamic population model to investigate effects of climate on geographic range and seasonality of the tick Ixodes scapularis","volume":"35","author":"NH Ogden","year":"2005","journal-title":"Int J Parasitol"},{"key":"pcbi.1012903.ref013","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.jtbi.2012.11.014","article-title":"Developing a temperature-driven map of the basic reproductive number of the emerging tick vector of Lyme disease Ixodes scapularis in Canada","volume":"319","author":"X Wu","year":"2013","journal-title":"J Theor Biol"},{"issue":"6","key":"pcbi.1012903.ref014","doi-asserted-by":"crossref","first-page":"609","DOI":"10.3390\/rs9060609","article-title":"Analyzing the potential risk of climate change on lyme disease in Eastern Ontario, Canada using time series remotely sensed temperature data and tick population modelling","volume":"9","author":"A Cheng","year":"2017","journal-title":"Remote Sensing"},{"key":"pcbi.1012903.ref015","article-title":"Deterministic models and temperature-driven R0 maps. In: Transmission dynamics of tick-borne diseases with co-feeding, developmental and behavioural diapause. Springer","author":"J Wu","year":"2020"},{"issue":"4","key":"pcbi.1012903.ref016","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1111\/j.1365-2664.2011.02003.x","article-title":"A modified matrix model to describe the seasonal population ecology of the European tick Ixodes ricinus","volume":"48","author":"ADM Dobson","year":"2011","journal-title":"J Appl Ecol"},{"key":"pcbi.1012903.ref017","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.ecolmodel.2012.06.007","article-title":"Simulation of climate\u2013host\u2013parasite\u2013landscape interactions: a spatially explicit model for ticks (Acari: Ixodidae)","volume":"243","author":"H-H Wang","year":"2012","journal-title":"Ecol Model"},{"issue":"1","key":"pcbi.1012903.ref018","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1186\/s13071-017-2261-y","article-title":"Impact of life stage-dependent dispersal on the colonization dynamics of host patches by ticks and tick-borne infectious agents","volume":"10","author":"S Kada","year":"2017","journal-title":"Parasit Vectors"},{"key":"pcbi.1012903.ref019","first-page":"75","article-title":"Emissions scenarios for the IPCC: an update","author":"J Leggett","year":"1992","journal-title":"Climate change."},{"issue":"2","key":"pcbi.1012903.ref020","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/BF03354031","article-title":"Overview of mitigation scenarios for global climate stabilization based on new IPCC emission scenarios (SRES)","volume":"3","author":"T Morita","year":"2000","journal-title":"Environ Econ Policy Stud"},{"key":"pcbi.1012903.ref021"},{"issue":"10","key":"pcbi.1012903.ref022","doi-asserted-by":"crossref","first-page":"104056","DOI":"10.1088\/1748-9326\/abb051","article-title":"Global surface air temperatures in CMIP6: historical performance and future changes","volume":"15","author":"X Fan","year":"2020","journal-title":"Environ Res Lett"},{"issue":"2","key":"pcbi.1012903.ref023","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/s41748-020-00157-7","article-title":"Projections of precipitation and temperature over the South Asian Countries in CMIP6","volume":"4","author":"M Almazroui","year":"2020","journal-title":"Earth Syst Environ"},{"issue":"7","key":"pcbi.1012903.ref024","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1007\/s12517-022-09848-z","article-title":"Projection of temperature and precipitation under climate change in Tabriz, Iran","volume":"15","author":"B Ghazi","year":"2022","journal-title":"Arab J Geosci"},{"issue":"1","key":"pcbi.1012903.ref025","doi-asserted-by":"crossref","first-page":"337","DOI":"10.2166\/wcc.2021.015","article-title":"Projected changes in temperature and precipitation over mainland Southeast Asia by CMIP6 models","volume":"13","author":"S Supharatid","year":"2022","journal-title":"J Water Climate Change."},{"issue":"4","key":"pcbi.1012903.ref026","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1603\/0022-2585-41.4.622","article-title":"Investigation of relationships between temperature and developmental rates of tick Ixodes scapularis (Acari: Ixodidae) in the laboratory and field","volume":"41","author":"NH Ogden","year":"2004","journal-title":"J Med Entomol"},{"issue":"4","key":"pcbi.1012903.ref027","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1093\/jme\/tjaa220","article-title":"Possible effects of climate change on ixodid ticks and the pathogens they transmit: predictions and observations","volume":"58","author":"NH Ogden","year":"2021","journal-title":"J Med Entomol"},{"issue":"1","key":"pcbi.1012903.ref028","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1186\/s13071-016-1894-6","article-title":"The impact of temperature and precipitation on blacklegged tick activity and Lyme disease incidence in endemic and emerging regions","volume":"9","author":"JC Burtis","year":"2016","journal-title":"Parasit Vectors"},{"issue":"7","key":"pcbi.1012903.ref029","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1002\/ece3.1014","article-title":"Climate of origin affects tick (Ixodes ricinus) host-seeking behavior in response to temperature: implications for resilience to climate change?","volume":"4","author":"L Gilbert","year":"2014","journal-title":"Ecol Evol"},{"issue":"116","key":"pcbi.1012903.ref030","doi-asserted-by":"crossref","first-page":"20160140","DOI":"10.1098\/rsif.2016.0140","article-title":"Modelling the seasonality of Lyme disease risk and the potential impacts of a warming climate within the heterogeneous landscapes of Scotland","volume":"13","author":"S Li","year":"2016","journal-title":"J R Soc Interface"},{"issue":"1","key":"pcbi.1012903.ref031","first-page":"1","article-title":"The potential impact of climate change on the transmission risk of tick-borne encephalitis in Hungary","volume":"20","author":"K Nah","year":"2020","journal-title":"BMC Infect Dis."},{"issue":"4","key":"pcbi.1012903.ref032","doi-asserted-by":"crossref","first-page":"83","DOI":"10.14745\/ccdr.v45i04a02","article-title":"N Increased risk of tick-borne diseases with climate and environmental changes","volume":"45","author":"C Bouchard","year":"2019","journal-title":"Can Commun Dis Rep"},{"key":"pcbi.1012903.ref033","doi-asserted-by":"crossref","first-page":"8448","DOI":"10.3402\/gha.v4i0.8448","article-title":"The impact of climate change on the expansion of Ixodes persulcatus habitat and the incidence of tick-borne encephalitis in the North of European Russia","volume":"4","author":"NK Tokarevich","year":"2011","journal-title":"Glob Health Action"},{"issue":"11","key":"pcbi.1012903.ref034","doi-asserted-by":"crossref","first-page":"e80724","DOI":"10.1371\/journal.pone.0080724","article-title":"Poleward expansion of the white-footed mouse (Peromyscus leucopus) under climate change: implications for the spread of lyme disease","volume":"8","author":"E Roy-Dufresne","year":"2013","journal-title":"PLoS One"},{"key":"pcbi.1012903.ref035","doi-asserted-by":"crossref","first-page":"110421","DOI":"10.1016\/j.ecolmodel.2023.110421","article-title":"A mathematical model of the impacts of climate change on the winter tick epizootic in moose","volume":"483","author":"DC Elzinga","year":"2023","journal-title":"Ecol Model"},{"issue":"217","key":"pcbi.1012903.ref036","doi-asserted-by":"crossref","first-page":"20240004","DOI":"10.1098\/rsif.2024.0004","article-title":"GIS-ODE: linking dynamic population models with GIS to predict pathogen vector abundance across a country under climate change scenarios","volume":"21","author":"AJ Worton","year":"2024","journal-title":"J R Soc Interface"},{"issue":"1","key":"pcbi.1012903.ref037","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s00442-009-1430-x","article-title":"Altitudinal patterns of tick and host abundance: a potential role for climate change in regulating tick-borne diseases?","volume":"162","author":"L Gilbert","year":"2010","journal-title":"Oecologia"},{"issue":"12","key":"pcbi.1012903.ref038","doi-asserted-by":"crossref","first-page":"e0189092","DOI":"10.1371\/journal.pone.0189092","article-title":"Climate change influences on the potential geographic distribution of the disease vector tick Ixodes ricinus","volume":"12","author":"AA Alkishe","year":"2017","journal-title":"PLoS One"},{"key":"pcbi.1012903.ref039"},{"issue":"1","key":"pcbi.1012903.ref040","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3390\/v13010010","article-title":"Prognostic factors of severe fever with thrombocytopenia syndrome in South Korea","volume":"13","author":"M Kim","year":"2020","journal-title":"Viruses"},{"issue":"9","key":"pcbi.1012903.ref041","doi-asserted-by":"crossref","first-page":"2292","DOI":"10.3201\/eid2609.200065","article-title":"Severe fever with thrombocytopenia syndrome virus in ticks and SFTS incidence in humans, South Korea","volume":"26","author":"JR Yoo","year":"2020","journal-title":"Emerg Infect Dis"},{"issue":"1","key":"pcbi.1012903.ref042","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/BF01200415","article-title":"Effects of temperature on development and growth in the tick, Haemaphysalis longicornis","volume":"3","author":"Y Yano","year":"1987","journal-title":"Exp Appl Acarol"},{"issue":"8","key":"pcbi.1012903.ref043","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/S0020-7519(02)00030-9","article-title":"An empirical quantitative framework for the seasonal population dynamics of the tick Ixodes ricinus","volume":"32","author":"SE Randolph","year":"2002","journal-title":"Int J Parasitol"},{"key":"pcbi.1012903.ref044","doi-asserted-by":"crossref","DOI":"10.5109\/23873","article-title":"Effects of humidity on development and growth in the tick, Haemaphysalis longicornis","author":"Y Yano","year":"1988","journal-title":"J Faculty Agricult Kyushu Univ"},{"key":"pcbi.1012903.ref045"},{"issue":"8","key":"pcbi.1012903.ref046","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.3390\/microorganisms9081630","article-title":"Nationwide temporal and geographical distribution of tick populations and phylogenetic analysis of severe fever with thrombocytopenia syndrome virus in ticks in Korea, 2020","volume":"9","author":"M-G Seo","year":"2021","journal-title":"Microorganisms"},{"issue":"4","key":"pcbi.1012903.ref047","first-page":"445","article-title":"Cytogenetics of ticks (Acari: Ixodoidea)","volume":"45","author":"Jr Oliver JH","year":"1974","journal-title":"14. Chromosomes of nine species of Asian haemaphysalines. Chromosoma"},{"issue":"1","key":"pcbi.1012903.ref048","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1186\/s13104-021-05740-3","article-title":"Data from expressed sequence tags from the organs and embryos of parthenogenetic Haemaphysalis longicornis","volume":"14","author":"R Umemiya-Shirafuji","year":"2021","journal-title":"BMC Res Notes"},{"issue":"1","key":"pcbi.1012903.ref049","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s11538-006-9125-5","article-title":"Modeling tick-borne disease: a metapopulation model","volume":"69","author":"HD Gaff","year":"2007","journal-title":"Bull Math Biol"},{"key":"pcbi.1012903.ref050"},{"key":"pcbi.1012903.ref051"},{"key":"pcbi.1012903.ref052"},{"issue":"3","key":"pcbi.1012903.ref053","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s10584-013-0905-2","article-title":"A new scenario framework for climate change research: the concept of shared socioeconomic pathways","volume":"122","author":"BC O\u2019Neill","year":"2013","journal-title":"Climatic Change"},{"issue":"9","key":"pcbi.1012903.ref054","doi-asserted-by":"crossref","first-page":"3461","DOI":"10.5194\/gmd-9-3461-2016","article-title":"The scenario model intercomparison project (ScenarioMIP) for CMIP6","volume":"9","author":"BC O\u2019Neill","year":"2016","journal-title":"Geosci Model Dev"},{"issue":"6","key":"pcbi.1012903.ref055","doi-asserted-by":"crossref","first-page":"e0199205","DOI":"10.1371\/journal.pone.0199205","article-title":"Potential effects of climate change on dengue transmission dynamics in Korea","volume":"13","author":"H Lee","year":"2018","journal-title":"PLoS One"},{"issue":"3","key":"pcbi.1012903.ref056","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1093\/jme\/tjz215","article-title":"Availability and nature of commercial tick control services in three lyme disease endemic states","volume":"57","author":"RA Jordan","year":"2020","journal-title":"J Med Entomol"},{"key":"pcbi.1012903.ref057"},{"issue":"44","key":"pcbi.1012903.ref058","first-page":"3103","article-title":"Evaluation of effectiveness of mowing works for integrated tick control method","volume":"14","author":"C Jang","year":"2021","journal-title":"Public Health Weekly Report."},{"issue":"4","key":"pcbi.1012903.ref059","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.aspen.2015.09.004","article-title":"Acaricidal activity of commercialized insecticides against Haemaphysalis longicornis (Acari: Ixodidae) nymphs","volume":"18","author":"D-W Lee","year":"2015","journal-title":"J Asia-Pacific Entomol"},{"issue":"43","key":"pcbi.1012903.ref060","first-page":"3040","article-title":"Evaluation of the acaricidal efficacy of Haemaphyslis longicornis","volume":"14","author":"G Kim","year":"2021","journal-title":"a vector of Severe Fever with Thrombocytopenia Syndrome (SFTS). Public Health Weekly Report."},{"issue":"1","key":"pcbi.1012903.ref061","doi-asserted-by":"crossref","first-page":"e4369","DOI":"10.1002\/ecs2.4369","article-title":"Climatic stress decreases tick survival but increases rate of host\u2010seeking behavior","volume":"14","author":"C Nielebeck","year":"2023","journal-title":"Ecosphere"},{"issue":"20","key":"pcbi.1012903.ref062","doi-asserted-by":"crossref","first-page":"e156","DOI":"10.3346\/jkms.2023.38.e156","article-title":"Coinfection of severe fever with thrombocytopenia syndrome virus and Coxiella Burnetii in developmental stage of hard ticks in subtropical region of Korea","volume":"38","author":"JR Yoo","year":"2023","journal-title":"J Korean Med Sci"},{"key":"pcbi.1012903.ref063"},{"issue":"1","key":"pcbi.1012903.ref064","doi-asserted-by":"crossref","first-page":"9","DOI":"10.17945\/kjbt.2015.26.1.9","article-title":"A choice and precautions of replacement fluids for therapeutic plasma exchange","volume":"26","author":"GR Choi","year":"2015","journal-title":"KJBT"},{"key":"pcbi.1012903.ref065"},{"key":"pcbi.1012903.ref066"},{"issue":"1","key":"pcbi.1012903.ref067","doi-asserted-by":"crossref","first-page":"65","DOI":"10.5206\/mase\/10508","article-title":"Modeling the impact of host resistance on structured tick population dynamics","volume":"1","author":"M Alavinejad","year":"2020","journal-title":"Math Appl Sci Eng"},{"issue":"13","key":"pcbi.1012903.ref068","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1017\/S003118200800036X","article-title":"Effect of host populations on the intensity of ticks and the prevalence of tick-borne pathogens: how to interpret the results of deer exclosure experiments","volume":"135","author":"A Pugliese","year":"2008","journal-title":"Parasitology"},{"key":"pcbi.1012903.ref069"},{"issue":"6","key":"pcbi.1012903.ref070","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1002\/jca.21935","article-title":"A nationwide population-based study on therapeutic plasma exchange for 10 years in Korea using Health Insurance Review and Assessment database","volume":"36","author":"JH Park","year":"2021","journal-title":"J Clin Apher"},{"issue":"3","key":"pcbi.1012903.ref071","first-page":"211","article-title":"Experience of therapeutic plasma exchange in patients with severe fever with thrombocytopenia syndrome","volume":"25","author":"S Kim","year":"2014","journal-title":"Korean J Blood Transfusion."},{"issue":"2","key":"pcbi.1012903.ref072","doi-asserted-by":"crossref","first-page":"83","DOI":"10.17945\/kjbt.2021.32.2.83","article-title":"Therapeutic plasma exchange in patients with severe fever with thrombocytopenia syndrome: a single institution experience","volume":"32","author":"E-H Yoo","year":"2021","journal-title":"KJBT"},{"key":"pcbi.1012903.ref073"},{"key":"pcbi.1012903.ref074"},{"issue":"5","key":"pcbi.1012903.ref075","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1093\/jme\/tjad093","article-title":"Community-based integrated tick management programs: cost and feasibility scenarios","volume":"60","author":"TL Schulze","year":"2023","journal-title":"J Med Entomol"},{"issue":"12","key":"pcbi.1012903.ref076","first-page":"2664","article-title":"Climate crises and developing vector-borne diseases: a narrative review","volume":"51","author":"N Mojahed","year":"2022","journal-title":"Iran J Public Health"},{"issue":"10371","key":"pcbi.1012903.ref077","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0140-6736(22)02353-4","article-title":"Climate change threatens our health and survival within decades","volume":"401","author":"A Costello","year":"2023","journal-title":"Lancet"},{"issue":"3","key":"pcbi.1012903.ref078","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.ijppaw.2015.07.001","article-title":"Climate change, biodiversity, ticks and tick-borne diseases: the butterfly effect","volume":"4","author":"F Dantas-Torres","year":"2015","journal-title":"Int J Parasitol Parasites Wildl"},{"issue":"4","key":"pcbi.1012903.ref079","doi-asserted-by":"crossref","first-page":"e12704","DOI":"10.1111\/1748-5967.12704","article-title":"Analysis of spatial and seasonal variations of Haemaphysalis longicornis population based on field survey collected under different habitats and years","volume":"54","author":"S Yoon","year":"2024","journal-title":"Entomol Res"},{"issue":"1","key":"pcbi.1012903.ref080","doi-asserted-by":"crossref","first-page":"101581","DOI":"10.1016\/j.ttbdis.2020.101581","article-title":"A life stage-targeted acaricide application approach for the control of Haemaphysalis longicornis","volume":"12","author":"M Bickerton","year":"2021","journal-title":"Ticks Tick Borne Dis"},{"issue":"4","key":"pcbi.1012903.ref081","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1645\/GE-1483.1","article-title":"Influence of aggregation and relative humidity on longevity of unfed bush tick, Haemaphysalis longicornis Neumann (Acari: Ixodidae)","volume":"94","author":"T Tsunoda","year":"2008","journal-title":"J Parasitol"},{"issue":"3","key":"pcbi.1012903.ref082","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1093\/jme\/tjz202","article-title":"Early Season Applications of Bifenthrin Suppress Host-seeking Ixodes scapularis and Amblyomma americanum (Acari: Ixodidae) Nymphs","volume":"57","author":"TL Schulze","year":"2020","journal-title":"J Med Entomol"},{"issue":"2","key":"pcbi.1012903.ref083","doi-asserted-by":"crossref","first-page":"172","DOI":"10.3390\/pathogens12020172","article-title":"Effects of neighborhood-scale acaricidal treatments on infection prevalence of blacklegged ticks (ixodes scapularis) with three zoonotic pathogens","volume":"12","author":"RS Ostfeld","year":"2023","journal-title":"Pathogens"},{"issue":"1665","key":"pcbi.1012903.ref084","doi-asserted-by":"crossref","first-page":"20140051","DOI":"10.1098\/rstb.2014.0051","article-title":"Climate change and Ixodes tick-borne diseases of humans","volume":"370","author":"RS Ostfeld","year":"2015","journal-title":"Philos Trans R Soc Lond B Biol Sci"}],"updated-by":[{"DOI":"10.1371\/journal.pcbi.1012903","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000}}],"container-title":["PLOS Computational Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pcbi.1012903","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T17:59:35Z","timestamp":1744826375000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pcbi.1012903"}},"subtitle":[],"editor":[{"given":"Narendra M","family":"Dixit","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,4,8]]},"references-count":84,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,4,8]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pcbi.1012903","relation":{"new_version":[{"id-type":"doi","id":"10.1371\/journal.pcbi.1012903","asserted-by":"object"}]},"ISSN":["1553-7358"],"issn-type":[{"value":"1553-7358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,8]]}}}