{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T18:19:33Z","timestamp":1778696373517,"version":"3.51.4"},"update-to":[{"DOI":"10.1371\/journal.pcbi.1014252","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T00:00:00Z","timestamp":1778630400000}}],"reference-count":81,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T00:00:00Z","timestamp":1778198400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.ploscompbiol.org"],"crossmark-restriction":false},"short-container-title":["PLoS Comput Biol"],"abstract":"<jats:p>Protecting public health from infectious diseases requires collective action, as individual behaviors\u2014such as vaccination and mask-wearing\u2014directly influence disease dynamics. During the COVID-19 pandemic, unexpected public responses often undermined the effectiveness of interventions, highlighting the need to understand collective behavioral patterns and motivations to design more effective mitigation strategies. This study presents an agent-based simulation model that captures how individuals adjust self-protective behaviors based on evolving opinions about disease risk and examines how these decisions interact with external factors, such as public health interventions, to shape collective outcomes. To improve the representativeness of the simulated population, multiple datasets were integrated to generate artificial populations. Model behavior was then calibrated against selected observed patterns, acknowledging that this calibration is partial and subject to model assumptions. Simulation experiments were conducted under varying conditions, including optional non-pharmaceutical interventions (NPIs), heterogeneous responses to pro- and anti-intervention messaging, and alternative vaccine eligibility policies. Results suggest that decision-making patterns may vary across demographic groups and that interactions between individual behaviors and external influences can substantially affect disease dynamics within the model. The simulation framework reproduces patterns consistent with observed phenomena, such as reduced mask-wearing following the lifting of mandates for vaccinated populations and higher infection burdens among economically disadvantaged populations. The framework suggests plausible mechanisms through which such patterns may emerge under the model assumptions. The study also suggests subpopulations likely to experience greater pressure under NPI mandates and highlights how vaccine eligibility strategies may enhance disease control when behavioral responses are considered. Overall, this work underscores the importance of integrating behavioral dynamics into epidemic response planning, while recognizing that findings are contingent on model structure and assumptions.<\/jats:p>","DOI":"10.1371\/journal.pcbi.1014252","type":"journal-article","created":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T23:11:12Z","timestamp":1778281872000},"page":"e1014252","update-policy":"https:\/\/doi.org\/10.1371\/journal.pcbi.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Modeling individual self-protective behavior during epidemics"],"prefix":"10.1371","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4394-0022","authenticated-orcid":true,"given":"Geonsik","family":"Yu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Garee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Ventresca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2087-7718","authenticated-orcid":true,"given":"Yuehwern","family":"Yih","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2026,5,8]]},"reference":[{"key":"pcbi.1014252.ref001","unstructured":"Wong T. Shincheonji and coronavirus: The mysterious \u2018cult\u2019 church blamed for S Korea\u2019s outbreak. BBC News. 2020;:14."},{"issue":"7826","key":"pcbi.1014252.ref002","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/d41586-020-02611-y","article-title":"\u201cWe didn\u2019t model that people would go to a party if they tested positive\u201d","volume":"585","author":"G Guglielmi","year":"2020","journal-title":"Nature"},{"key":"pcbi.1014252.ref003","doi-asserted-by":"crossref","unstructured":"Bernheim BD, Buchmann N, Freitas-Groff Z, Otero S. The effects of large group meetings on the spread of COVID-19: The case of Trump rallies. The Effects of Large Group Meetings on the Spread of COVID-19: The Case of Trump Rallies. 2020.","DOI":"10.2139\/ssrn.3722299"},{"issue":"50","key":"pcbi.1014252.ref004","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1098\/rsif.2010.0142","article-title":"Modelling the influence of human behaviour on the spread of infectious diseases: a review","volume":"7","author":"S Funk","year":"2010","journal-title":"J R Soc Interface"},{"key":"pcbi.1014252.ref005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.physrep.2016.10.006","article-title":"Statistical physics of vaccination","volume":"664","author":"Z Wang","year":"2016","journal-title":"Physics Reports"},{"issue":"125","key":"pcbi.1014252.ref006","doi-asserted-by":"crossref","first-page":"20160820","DOI":"10.1098\/rsif.2016.0820","article-title":"Behavioural change models for infectious disease transmission: a systematic review (2010-2015)","volume":"13","author":"F Verelst","year":"2016","journal-title":"J R Soc Interface"},{"issue":"3","key":"pcbi.1014252.ref007","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1086\/719918","article-title":"Partisanship and the Politics of COVID Vaccine Hesitancy","volume":"54","author":"DR Jones","year":"2022","journal-title":"Polity"},{"issue":"4","key":"pcbi.1014252.ref008","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1093\/pubmed\/fdad105","article-title":"Perceptions of COVID-19 vaccine side effects by political affiliation","volume":"45","author":"D Farabee","year":"2023","journal-title":"J Public Health (Oxf)"},{"issue":"12","key":"pcbi.1014252.ref009","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0208601","article-title":"Beyond confidence: Development of a measure assessing the 5C psychological antecedents of vaccination","volume":"13","author":"C Betsch","year":"2018","journal-title":"PLoS One"},{"issue":"5","key":"pcbi.1014252.ref010","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1007\/s40615-021-01117-1","article-title":"Racial\/Ethnic Differences in Prosocial Beliefs and Prevention Behavior During the COVID-19 Pandemic","volume":"9","author":"H Orom","year":"2022","journal-title":"J Racial Ethn Health Disparities"},{"issue":"1","key":"pcbi.1014252.ref011","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1353\/hpu.2021.0010","article-title":"Institutional Distrust among African Americans and Building Trustworthiness in the COVID-19 Response: Implications for Ethical Public Health Practice","volume":"32","author":"AL Best","year":"2021","journal-title":"J Health Care Poor Underserved"},{"issue":"11","key":"pcbi.1014252.ref012","doi-asserted-by":"crossref","first-page":"7918","DOI":"10.1007\/s12144-020-01211-3","article-title":"Behavioral and psychosocial factors associated with COVID-19 skepticism in the United States","volume":"41","author":"CA Latkin","year":"2022","journal-title":"Curr Psychol"},{"key":"pcbi.1014252.ref013","doi-asserted-by":"crossref","unstructured":"Poterek ML, Santos-Vega M, Perkins TA. Equilibrium properties of a coupled contagion model of mosquito-borne disease and mosquito preventive behaviors. medRxiv. 2025;:2025\u201302.","DOI":"10.1101\/2025.02.01.25321519"},{"issue":"16","key":"pcbi.1014252.ref014","doi-asserted-by":"crossref","first-page":"6872","DOI":"10.1073\/pnas.0810762106","article-title":"The spread of awareness and its impact on epidemic outbreaks","volume":"106","author":"S Funk","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"pcbi.1014252.ref015","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1186\/s12889-024-18310-6","article-title":"How individuals\u2019 opinions influence society\u2019s resistance to epidemics: an agent-based model approach","volume":"24","author":"G Yu","year":"2024","journal-title":"BMC Public Health"},{"issue":"12","key":"pcbi.1014252.ref016","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0208775","article-title":"An open-data-driven agent-based model to simulate infectious disease outbreaks","volume":"13","author":"E Hunter","year":"2018","journal-title":"PLoS One"},{"issue":"7","key":"pcbi.1014252.ref017","article-title":"Covasim: An agent-based model of COVID-19 dynamics and interventions","volume":"17","author":"CC Kerr","year":"2021","journal-title":"PLoS Comput Biol"},{"issue":"36","key":"pcbi.1014252.ref018","doi-asserted-by":"crossref","first-page":"13391","DOI":"10.1073\/pnas.0403823101","article-title":"Vaccination and the theory of games","volume":"101","author":"CT Bauch","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"2","key":"pcbi.1014252.ref019","doi-asserted-by":"crossref","first-page":"124","DOI":"10.3390\/fractalfract9020124","article-title":"Overview and research prospects on fractional co-evolution modeling of \u201cepidemic\u2013opinion\u201d system","volume":"9","author":"D Ding","year":"2025","journal-title":"Fractal and Fractional"},{"key":"pcbi.1014252.ref020","unstructured":"Bricker D. Ipsos press release. https\/\/www.ipsos.com\/sites\/default\/files\/ct\/news\/documents\/2020-04\/coronavirus-wave-8-april-16-pr-ipsos.pdf 2022."},{"key":"pcbi.1014252.ref021","unstructured":"Ellison G. YouGov Data, COVID-19 Behaviour Tracker. https:\/\/github.com\/YouGov-Data\/COVID-19-tracker\/. 2023."},{"issue":"5","key":"pcbi.1014252.ref022","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1177\/1075547020950735","article-title":"Politicization and polarization in COVID-19 news coverage","volume":"42","author":"PS Hart","year":"2020","journal-title":"Science Communication"},{"issue":"345","key":"pcbi.1014252.ref023","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1080\/01621459.1974.10480137","article-title":"Reaching a Consensus","volume":"69","author":"MH Degroot","year":"1974","journal-title":"Journal of the American Statistical Association"},{"issue":"6","key":"pcbi.1014252.ref024","doi-asserted-by":"crossref","DOI":"10.1140\/epjp\/s13360-020-00541-2","article-title":"Recent advances in opinion propagation dynamics: a 2020 survey","volume":"135","author":"H Noorazar","year":"2020","journal-title":"Eur Phys J Plus"},{"issue":"4","key":"pcbi.1014252.ref025","doi-asserted-by":"crossref","DOI":"10.18564\/jasss.3521","article-title":"Models of Social Influence: Towards the Next Frontiers","volume":"20","author":"A Flache","year":"2017","journal-title":"JASSS"},{"issue":"4","key":"pcbi.1014252.ref026","article-title":"How can extremism prevail? A study based on the relative agreement interaction model","volume":"5","author":"G Deffuant","year":"2002","journal-title":"Journal of Artificial Societies & Social Simulation"},{"issue":"3","key":"pcbi.1014252.ref027","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1109\/TCNS.2022.3145748","article-title":"On a Networked SIS Epidemic Model With Cooperative and Antagonistic Opinion Dynamics","volume":"9","author":"B She","year":"2022","journal-title":"IEEE Trans Control Netw Syst"},{"issue":"4","key":"pcbi.1014252.ref028","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1109\/LCSYS.2020.3035873","article-title":"Influence of Opinion Dynamics to Inhibit Epidemic Spreading Over Multiplex Network","volume":"5","author":"S Bhowmick","year":"2021","journal-title":"IEEE Control Syst Lett"},{"issue":"1","key":"pcbi.1014252.ref029","doi-asserted-by":"crossref","DOI":"10.18564\/jasss.4723","article-title":"Fear, Behaviour, and the COVID-19 Pandemic: A City-Scale Agent-Based Model Using Socio-Demographic and Spatial Map Data","volume":"25","author":"CO Retzlaff","year":"2022","journal-title":"JASSS"},{"issue":"5","key":"pcbi.1014252.ref030","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1000793","article-title":"Game theory of social distancing in response to an epidemic","volume":"6","author":"TC Reluga","year":"2010","journal-title":"PLoS Comput Biol"},{"key":"pcbi.1014252.ref031","doi-asserted-by":"crossref","first-page":"102804","DOI":"10.1016\/j.apgeog.2022.102804","article-title":"Assessing the spatial variability of raising public risk awareness for the intervention performance of COVID-19 voluntary screening: A spatial simulation approach","volume":"148","author":"F-Y Kuo","year":"2022","journal-title":"Appl Geogr"},{"issue":"29","key":"pcbi.1014252.ref032","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1098\/rsif.2008.0271","article-title":"The effect of opinion clustering on disease outbreaks","volume":"5","author":"M Salath\u00e9","year":"2008","journal-title":"J R Soc Interface"},{"key":"pcbi.1014252.ref033","author":"G Yu","year":"2025"},{"issue":"8","key":"pcbi.1014252.ref034","doi-asserted-by":"crossref","first-page":"3375","DOI":"10.1016\/j.cnsns.2010.11.019","article-title":"Epidemic spreading of an SEIRS model in scale-free networks","volume":"16","author":"J Liu","year":"2011","journal-title":"Communications in Nonlinear Science and Numerical Simulation"},{"issue":"23","key":"pcbi.1014252.ref035","doi-asserted-by":"crossref","first-page":"2760","DOI":"10.1016\/j.ecolmodel.2010.08.019","article-title":"The ODD protocol: A review and first update","volume":"221","author":"V Grimm","year":"2010","journal-title":"Ecological Modelling"},{"key":"pcbi.1014252.ref036","unstructured":"Magee JF. Decision trees for decision making. Harvard Business Review. 1964."},{"key":"pcbi.1014252.ref037","doi-asserted-by":"crossref","unstructured":"Kaas R, Goovaerts M, Dhaene J, Denuit M. Utility theory and insurance. Modern actuarial risk theory. 2008. p. 1\u201316.","DOI":"10.1007\/978-3-540-70998-5_1"},{"issue":"1","key":"pcbi.1014252.ref038","doi-asserted-by":"crossref","DOI":"10.1002\/mds3.10163","article-title":"How effective is a mask in preventing COVID-19 infection?","volume":"4","author":"Y Wang","year":"2021","journal-title":"Medical Devices & Sensors"},{"key":"pcbi.1014252.ref039","doi-asserted-by":"crossref","DOI":"10.1101\/2020.05.31.20118521","article-title":"Summer vacation and COVID-19: effects of metropolitan people going to summer provinces. arXiv preprint","author":"T Britton","year":"2020"},{"issue":"4","key":"pcbi.1014252.ref040","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1111\/jors.12539","article-title":"Learning from deregulation: The asymmetric impact of lockdown and reopening on risky behavior during COVID-19","volume":"61","author":"EL Glaeser","year":"2021","journal-title":"J Reg Sci"},{"key":"pcbi.1014252.ref041","doi-asserted-by":"crossref","unstructured":"Yamana T, Pei S, Kandula S, Shaman J. Projection of COVID-19 cases and deaths in the US as individual states re-open. MedRxiv. 2020;:2020\u201305.","DOI":"10.1101\/2020.05.04.20090670"},{"key":"pcbi.1014252.ref042","unstructured":"Bureau UC. PINC-01. Selected characteristics of people 15 years and over, by total money income, work experience, race, Hispanic origin, and sex. 2024. https:\/\/www.census.gov\/data\/tables\/time-series\/demo\/income-poverty\/cps-pinc\/pinc-01.2019.html"},{"issue":"1","key":"pcbi.1014252.ref043","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/s41467-020-20544-y","article-title":"Inferring high-resolution human mixing patterns for disease modeling","volume":"12","author":"D Mistry","year":"2021","journal-title":"Nat Commun"},{"key":"pcbi.1014252.ref044","unstructured":"World Health Organization. WHO COVID-19 dashboard. https:\/\/data.who.int\/dashboards\/covid19. 2023."},{"key":"pcbi.1014252.ref045","unstructured":"Centers for Disease Control and Prevention. Weekly United States COVID-19 Cases and Deaths by State. https:\/\/data.cdc.gov\/Case-Surveillance\/Weekly-United-States-COVID-19-Cases-and-Deaths-by-\/pwn4-m3yp 2025."},{"key":"pcbi.1014252.ref046","unstructured":"Thomas K, Weiland N, LaFraniere S. Advisory panel gives green light to pfizer vaccine. The New York Times. 2020;:10."},{"key":"pcbi.1014252.ref047","unstructured":"Anthes E, Ngo M, Sullivan E. Adults in all US states are now eligible for vaccination, hitting Biden\u2019s target. Half have had at least one dose. The New York Times. 2021."},{"key":"pcbi.1014252.ref048","doi-asserted-by":"crossref","unstructured":"Selberg S, Sundbaum JK, Konradsen JR, Backman H, Hedman L, Lindberg A. Multiple manifestations of uncontrolled asthma increase the risk of severe COVID-19. Respiratory Medicine. 2023;:107308.","DOI":"10.1016\/j.rmed.2023.107308"},{"key":"pcbi.1014252.ref049","unstructured":"Westesson K. FHM: 16\u201317-\u00e5ringar ska erbjudas vaccin. https:\/\/www.svd.se\/a\/415326\/ekstrom-och-carlson-om-vaccin-till-barn 2021."},{"key":"pcbi.1014252.ref050","doi-asserted-by":"crossref","unstructured":"Schulman J, Lazer D, Perlis R, Baum M, Cadenasso S, Ognyanova K. The COVID States Project# 96: State of the COVID-19 Pandemic. 2022.","DOI":"10.31219\/osf.io\/tz3a4"},{"key":"pcbi.1014252.ref051","article-title":"Forschungsbericht","author":"D Kraft","year":"1988"},{"key":"pcbi.1014252.ref052","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2012\/674832","article-title":"Basin Hopping as a General and Versatile Optimization Framework for the Characterization of Biological Macromolecules","volume":"2012","author":"B Olson","year":"2012","journal-title":"Advances in Artificial Intelligence"},{"issue":"4","key":"pcbi.1014252.ref053","doi-asserted-by":"crossref","first-page":"766","DOI":"10.3390\/v14040766","article-title":"Early Emergence Phase of SARS-CoV-2 Delta Variant in Florida, US","volume":"14","author":"E Cella","year":"2022","journal-title":"Viruses"},{"issue":"4","key":"pcbi.1014252.ref054","doi-asserted-by":"crossref","first-page":"154","DOI":"10.7758\/RSF.2024.10.4.07","article-title":"Discourses of Distrust: How Lack of Trust in the U.S. Health-Care System Shaped COVID-19 Vaccine Hesitancy","volume":"10","author":"A Casselman-Hontalas","year":"2024","journal-title":"rsf"},{"issue":"7","key":"pcbi.1014252.ref055","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.24984","article-title":"Trust in Physicians and Hospitals During the COVID-19 Pandemic in a 50-State Survey of US Adults","volume":"7","author":"RH Perlis","year":"2024","journal-title":"JAMA Netw Open"},{"issue":"4","key":"pcbi.1014252.ref056","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1111\/j.1571-9979.1991.tb00634.x","article-title":"Barriers to Conflict Resolution","volume":"7","author":"L Ross","year":"1991","journal-title":"Negotiation Journal"},{"issue":"6532","key":"pcbi.1014252.ref057","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1126\/science.abe6959","article-title":"Model-informed COVID-19 vaccine prioritization strategies by age and serostatus","volume":"371","author":"KM Bubar","year":"2021","journal-title":"Science"},{"key":"pcbi.1014252.ref058","doi-asserted-by":"crossref","unstructured":"Smits J, Malik AA, Elharake JA, Mobarak AM, Omer SB. Did risk-based or age-based vaccine prioritization for COVID-19 save more lives?. medRxiv. 2022;:2022\u201310.","DOI":"10.1101\/2022.10.18.22281237"},{"issue":"16","key":"pcbi.1014252.ref059","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2025786118","article-title":"Dynamic prioritization of COVID-19 vaccines when social distancing is limited for essential workers","volume":"118","author":"JH Buckner","year":"2021","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"4","key":"pcbi.1014252.ref060","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3001211","article-title":"Evaluation of COVID-19 vaccination strategies with a delayed second dose","volume":"19","author":"SM Moghadas","year":"2021","journal-title":"PLoS Biol"},{"issue":"1","key":"pcbi.1014252.ref061","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1186\/s12889-021-10561-x","article-title":"Human mobility and poverty as key drivers of COVID-19 transmission and control","volume":"21","author":"M Yechezkel","year":"2021","journal-title":"BMC Public Health"},{"key":"pcbi.1014252.ref062","doi-asserted-by":"crossref","DOI":"10.15585\/mmwr.mm7226a5","article-title":"Disparities in COVID-19 disease incidence by income and vaccination coverage\u201481 communities, Los Angeles, California, July 2020\u2013September 2021","volume":"72","author":"JM Masterson","year":"2023","journal-title":"MMWR Morbidity and Mortality Weekly Report"},{"issue":"12","key":"pcbi.1014252.ref063","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1136\/jech-2020-216068","article-title":"Low-income neighbourhood was a key determinant of severe COVID-19 incidence during the first wave of the epidemic in Paris","volume":"75","author":"A-S Jannot","year":"2021","journal-title":"J Epidemiol Community Health"},{"issue":"6536","key":"pcbi.1014252.ref064","doi-asserted-by":"crossref","DOI":"10.1126\/science.abe8372","article-title":"Age groups that sustain resurging COVID-19 epidemics in the United States","volume":"371","author":"M Monod","year":"2021","journal-title":"Science"},{"key":"pcbi.1014252.ref065","unstructured":"Duca LM, Xu L, Price SF, McLean CA. COVID-19 stats: COVID-19 incidence, by age group - United States, March 1\u2013November 14, 2020 \u00a7. Morbidity and Mortality Weekly Report. 2021."},{"issue":"3","key":"pcbi.1014252.ref066","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1136\/jech-2021-216876","article-title":"Patterns of compliance with COVID-19 preventive behaviours: a latent class analysis of 20 000 UK adults","volume":"76","author":"L Wright","year":"2022","journal-title":"J Epidemiol Community Health"},{"issue":"2","key":"pcbi.1014252.ref067","doi-asserted-by":"crossref","first-page":"59","DOI":"10.21071\/psye.v14i2.14574","article-title":"Compliance with COVID-19 measures in adolescents and related sociodemographic and educational variables","volume":"14","author":"R Espejo-Siles","year":"2022","journal-title":"psye"},{"issue":"9","key":"pcbi.1014252.ref068","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.3201\/eid2909.221754","article-title":"Compliance trajectory and patterns of COVID-19 preventive measures, Japan, 2020\u20132022","volume":"29","author":"T Kusama","year":"2023","journal-title":"Emerging Infectious Diseases"},{"issue":"2","key":"pcbi.1014252.ref069","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.imj.2023.03.001","article-title":"Hesitant adopters: COVID-19 vaccine hesitancy among diverse vaccinated adults in the United States","volume":"2","author":"S Reece","year":"2023","journal-title":"Infect Med (Beijing)"},{"key":"pcbi.1014252.ref070","doi-asserted-by":"crossref","first-page":"877668","DOI":"10.3389\/fpubh.2022.877668","article-title":"COVID-19 vaccine hesitancy among older adolescents and young adults: a national cross-sectional study in China","volume":"10","author":"P Zhang","year":"2022","journal-title":"Frontiers in Public Health"},{"issue":"8","key":"pcbi.1014252.ref071","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.3390\/vaccines11081301","article-title":"Socioeconomic Inequalities in COVID-19 Vaccine Hesitancy and Uptake in Greece and Cyprus during the Pandemic","volume":"11","author":"II Pouliasi","year":"2023","journal-title":"Vaccines (Basel)"},{"issue":"2","key":"pcbi.1014252.ref072","doi-asserted-by":"crossref","first-page":"265","DOI":"10.3390\/vaccines10020265","article-title":"Factors Affecting Young Adults\u2019 Decision Making to Undergo COVID-19 Vaccination: A Patient Preference Study","volume":"10","author":"G Donin","year":"2022","journal-title":"Vaccines (Basel)"},{"issue":"1","key":"pcbi.1014252.ref073","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1038\/s41541-024-00893-1","article-title":"Myocarditis associated with COVID-19 vaccination","volume":"9","author":"A Buoninfante","year":"2024","journal-title":"NPJ Vaccines"},{"key":"pcbi.1014252.ref074","unstructured":"Gamble VN. Under the shadow of Tuskegee: African Americans and health care. Health Psychology. 2016;:418\u201325."},{"issue":"11","key":"pcbi.1014252.ref075","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.2105\/AJPH.2022.307088","article-title":"50 Years After the Tuskegee Revelations: Why Does the Mistrust Linger?","volume":"112","author":"JH Jones","year":"2022","journal-title":"Am J Public Health"},{"issue":"2","key":"pcbi.1014252.ref076","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1177\/1532673X221118888","article-title":"Political Partisanship and Trust in Government Predict Popular Support for COVID-19 Vaccine Mandates for Various Professions and Demographic Groups: A Research Note","volume":"51","author":"F Viskupi\u010d","year":"2023","journal-title":"Am Polit Res"},{"issue":"2","key":"pcbi.1014252.ref077","doi-asserted-by":"crossref","first-page":"148","DOI":"10.3390\/epidemiologia3020012","article-title":"Trust in the U.S. Government and Its Health Agencies in the Time of COVID-19","volume":"3","author":"M Geisterfer-Black","year":"2022","journal-title":"Epidemiologia (Basel)"},{"key":"pcbi.1014252.ref078","volume-title":"Open Forum Infectious Diseases","author":"A Richterman","year":"2022"},{"issue":"1","key":"pcbi.1014252.ref079","doi-asserted-by":"crossref","DOI":"10.1093\/jlb\/lsaa050","article-title":"COVID-19 vaccine: vaccinate the young to protect the old?","volume":"7","author":"A Giubilini","year":"2020","journal-title":"J Law Biosci"},{"issue":"11","key":"pcbi.1014252.ref080","doi-asserted-by":"crossref","first-page":"2522","DOI":"10.1080\/21645515.2015.1082014","article-title":"Vaccination of healthcare workers: A review","volume":"11","author":"S Haviari","year":"2015","journal-title":"Hum Vaccin Immunother"},{"issue":"10","key":"pcbi.1014252.ref081","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgph.0000020","article-title":"Vaccine rollout strategies: The case for vaccinating essential workers early","volume":"1","author":"N Mulberry","year":"2021","journal-title":"PLOS Glob Public Health"}],"updated-by":[{"DOI":"10.1371\/journal.pcbi.1014252","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T00:00:00Z","timestamp":1778630400000}}],"container-title":["PLOS Computational Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pcbi.1014252","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T17:55:04Z","timestamp":1778694904000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pcbi.1014252"}},"subtitle":[],"editor":[{"given":"Kimberly M.","family":"Pepin","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,5,8]]},"references-count":81,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,5,8]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pcbi.1014252","relation":{},"ISSN":["1553-7358"],"issn-type":[{"value":"1553-7358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,8]]}}}