{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T18:07:15Z","timestamp":1789668435813,"version":"4.0.1"},"reference-count":11,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.ploscompbiol.org"],"crossmark-restriction":false},"short-container-title":["PLoS Comput Biol"],"DOI":"10.1371\/journal.pcbi.1014789","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T17:33:41Z","timestamp":1789666421000},"page":"e1014789","update-policy":"https:\/\/doi.org\/10.1371\/journal.pcbi.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["When models choose metrics: Hidden geometry in computational biology"],"prefix":"10.1371","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4594-4219","authenticated-orcid":true,"given":"Dillion M.","family":"Fox","sequence":"first","affiliation":[{"name":"GSK","place":["Collegeville, Pennsylvania, United States of America"],"department":["AIML"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,9,17]]},"reference":[{"issue":"4","key":"pcbi.1014789.ref001","doi-asserted-by":"crossref","first-page":"325","DOI":"10.2307\/1942268","article-title":"An ordination of the upland forest communities of southern Wisconsin","volume":"27","author":"JR Bray","year":"1957","journal-title":"Ecol Monogr"},{"issue":"12","key":"pcbi.1014789.ref002","doi-asserted-by":"crossref","first-page":"8228","DOI":"10.1128\/AEM.71.12.8228-8235.2005","article-title":"UniFrac: a new phylogenetic method for comparing microbial communities","volume":"71","author":"C Lozupone","year":"2005","journal-title":"Appl Environ Microbiol"},{"issue":"5","key":"pcbi.1014789.ref003","doi-asserted-by":"crossref","first-page":"485","DOI":"10.3390\/e21050485","article-title":"On the Jensen-Shannon symmetrization of distances relying on abstract means","volume":"21","author":"F Nielsen","year":"2019","journal-title":"Entropy (Basel)"},{"key":"pcbi.1014789.ref004","volume-title":"Methods of information geometry","author":"SI Amari","year":"2000"},{"key":"pcbi.1014789.ref005","volume-title":"Statistical decision rules and optimal inference","author":"NN Chentsov","year":"1982"},{"key":"pcbi.1014789.ref006","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-319-56478-4","volume-title":"Information geometry","author":"N Ay","year":"2017"},{"issue":"1","key":"pcbi.1014789.ref007","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s41884-018-0006-4","article-title":"Chentsov\u2019s theorem for exponential families","volume":"1","author":"JG Dowty","year":"2018","journal-title":"Info Geo"},{"issue":"2","key":"pcbi.1014789.ref008","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.2517-6161.1982.tb01195.x","article-title":"The statistical analysis of compositional data","volume":"44","author":"J Aitchison","year":"1982","journal-title":"J R Stat Soc Series B Stat Methodol"},{"issue":"1","key":"pcbi.1014789.ref009","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s41884-023-00104-1","article-title":"Power transformations of relative count data as a shrinkage problem","volume":"6","author":"I Erb","year":"2023","journal-title":"Info Geo"},{"key":"pcbi.1014789.ref010","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/978-3-030-71175-7_2","article-title":"The information-geometric perspective of compositional data analysis.","volume-title":"Advances in compositional data analysis","author":"I Erb","year":"2021"},{"issue":"12","key":"pcbi.1014789.ref011","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"MI Love","year":"2014","journal-title":"Genome Biol"}],"container-title":["PLOS Computational Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pcbi.1014789","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T17:33:43Z","timestamp":1789666423000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pcbi.1014789"}},"subtitle":[],"editor":[{"given":"Feilim","family":"Mac Gabhann","sequence":"first","affiliation":[{"name":"Johns Hopkins University","place":["UNITED STATES OF AMERICA"]}],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,9,17]]},"references-count":11,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,9,17]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pcbi.1014789","relation":{},"ISSN":["1553-7358"],"issn-type":[{"value":"1553-7358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,17]]}}}