{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T03:39:25Z","timestamp":1775619565682,"version":"3.50.1"},"reference-count":37,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T00:00:00Z","timestamp":1241740800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosgenetics.org"],"crossmark-restriction":false},"short-container-title":["PLoS Genet"],"DOI":"10.1371\/journal.pgen.1000468","type":"journal-article","created":{"date-parts":[[2009,5,7]],"date-time":"2009-05-07T21:14:20Z","timestamp":1241730860000},"page":"e1000468","update-policy":"https:\/\/doi.org\/10.1371\/journal.pgen.corrections_policy","source":"Crossref","is-referenced-by-count":17,"title":["Evaluation of Haplotype Inference Using Definitive Haplotype Data Obtained from Complete Hydatidiform Moles, and Its Significance for the Analyses of Positively Selected Regions"],"prefix":"10.1371","volume":"5","author":[{"given":"Koichiro","family":"Higasa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoji","family":"Kukita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyoko","family":"Kato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norio","family":"Wake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoko","family":"Tahira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenshi","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2009,5,8]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1038\/nature06258","article-title":"A second generation human haplotype map of over 3.1 million SNPs.","volume":"449","author":"KA Frazer","year":"2007","journal-title":"Nature"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1038\/nature04226","article-title":"A haplotype map of the human genome.","volume":"437","year":"2005","journal-title":"Nature"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"e254","DOI":"10.1371\/journal.pbio.0050254","article-title":"The diploid genome sequence of an individual human.","volume":"5","author":"S Levy","year":"2007","journal-title":"PLoS Biol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1086\/428594","article-title":"Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation.","volume":"76","author":"M Stephens","year":"2005","journal-title":"Am J Hum Genet"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1086\/521987","article-title":"Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering.","volume":"81","author":"SR Browning","year":"2007","journal-title":"Am J Hum Genet"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.ajhg.2009.01.005","article-title":"A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals.","volume":"84","author":"BL Browning","year":"2009","journal-title":"Am J Hum Genet"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1186\/1471-2105-7-542","article-title":"HaploRec: efficient and accurate large-scale reconstruction of haplotypes.","volume":"7","author":"L Eronen","year":"2006","journal-title":"BMC Bioinformatics"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1086\/502802","article-title":"A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase.","volume":"78","author":"P Scheet","year":"2006","journal-title":"Am J Hum Genet"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1086\/500808","article-title":"A comparison of phasing algorithms for trios and unrelated individuals.","volume":"78","author":"J Marchini","year":"2006","journal-title":"Am J Hum Genet"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1002\/gepi.20185","article-title":"Understanding the accuracy of statistical haplotype inference with sequence data of known phase.","volume":"31","author":"AM Andres","year":"2007","journal-title":"Genet Epidemiol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"D685","DOI":"10.1093\/nar\/gkl848","article-title":"D-HaploDB: a database of definitive haplotypes determined by genotyping complete hydatidiform mole samples.","volume":"35","author":"K Higasa","year":"2007","journal-title":"Nucleic Acids Res"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1101\/gr.4371105","article-title":"Genome-wide definitive haplotypes determined using a collection of complete hydatidiform moles.","volume":"15","author":"Y Kukita","year":"2005","journal-title":"Genome Res"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1006\/geno.2001.6676","article-title":"Paternal origins of complete hydatidiform moles proven by whole genome single-nucleotide polymorphism haplotyping.","volume":"79","author":"JB Fan","year":"2002","journal-title":"Genomics"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1006\/geno.1997.5042","article-title":"The homozygous complete hydatidiform mole: a unique resource for genome studies.","volume":"46","author":"P Taillon-Miller","year":"1997","journal-title":"Genomics"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1038\/nature01140","article-title":"Detecting recent positive selection in the human genome from haplotype structure.","volume":"419","author":"PC Sabeti","year":"2002","journal-title":"Nature"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1038\/nature06250","article-title":"Genome-wide detection and characterization of positive selection in human populations.","volume":"449","author":"PC Sabeti","year":"2007","journal-title":"Nature"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"e72","DOI":"10.1371\/journal.pbio.0040072","article-title":"A map of recent positive selection in the human genome.","volume":"4","author":"BF Voight","year":"2006","journal-title":"PLoS Biol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"e171","DOI":"10.1371\/journal.pbio.0050171","article-title":"A new approach for using genome scans to detect recent positive selection in the human genome.","volume":"5","author":"K Tang","year":"2007","journal-title":"PLoS Biol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"e190","DOI":"10.1371\/journal.pgen.0020190","article-title":"Population structure and eigenanalysis.","volume":"2","author":"N Patterson","year":"2006","journal-title":"PLoS Genet"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1038\/ng1847","article-title":"Principal components analysis corrects for stratification in genome-wide association studies.","volume":"38","author":"AL Price","year":"2006","journal-title":"Nat Genet"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/ng1001-233","article-title":"Haplotype tagging for the identification of common disease genes.","volume":"29","author":"GC Johnson","year":"2001","journal-title":"Nat Genet"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1086\/381000","article-title":"Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium.","volume":"74","author":"CS Carlson","year":"2004","journal-title":"Am J Hum Genet"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"e114","DOI":"10.1371\/journal.pgen.0030114","article-title":"Imputation-based analysis of association studies: candidate regions and quantitative traits.","volume":"3","author":"B Servin","year":"2007","journal-title":"PLoS Genet"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1038\/ng2088","article-title":"A new multipoint method for genome-wide association studies by imputation of genotypes.","volume":"39","author":"J Marchini","year":"2007","journal-title":"Nat Genet"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1038\/ng1911","article-title":"A worldwide survey of haplotype variation and linkage disequilibrium in the human genome.","volume":"38","author":"DF Conrad","year":"2006","journal-title":"Nat Genet"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1038\/ng1885","article-title":"A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC.","volume":"38","author":"PI de Bakker","year":"2006","journal-title":"Nat Genet"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/ng1946","article-title":"Convergent adaptation of human lactase persistence in Africa and Europe.","volume":"39","author":"SA Tishkoff","year":"2007","journal-title":"Nat Genet"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1086\/421051","article-title":"Genetic signatures of strong recent positive selection at the lactase gene.","volume":"74","author":"T Bersaglieri","year":"2004","journal-title":"Am J Hum Genet"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1086\/379378","article-title":"A comparison of bayesian methods for haplotype reconstruction from population genotype data.","volume":"73","author":"M Stephens","year":"2003","journal-title":"Am J Hum Genet"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1086\/344347","article-title":"Haplotype inference in random population samples.","volume":"71","author":"S Lin","year":"2002","journal-title":"Am J Hum Genet"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1126\/science.1092500","article-title":"The fine-scale structure of recombination rate variation in the human genome.","volume":"304","author":"GA McVean","year":"2004","journal-title":"Science"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/0040-5809(77)90023-5","article-title":"Is the most frequent allele the oldest?","volume":"11","author":"GA Watterson","year":"1977","journal-title":"Theor Popul Biol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1038\/ng1508","article-title":"A common inversion under selection in Europeans.","volume":"37","author":"H Stefansson","year":"2005","journal-title":"Nat Genet"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1126\/science.1162986","article-title":"Real-time DNA sequencing from single polymerase molecules.","volume":"323","author":"J Eid","year":"2009","journal-title":"Science"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nature03959","article-title":"Genome sequencing in microfabricated high-density picolitre reactors.","volume":"437","author":"M Margulies","year":"2005","journal-title":"Nature"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1101\/gr.3770505","article-title":"Emerging technologies in DNA sequencing.","volume":"15","author":"ML Metzker","year":"2005","journal-title":"Genome Res"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1126\/science.1117389","article-title":"Accurate multiplex polony sequencing of an evolved bacterial genome.","volume":"309","author":"J Shendure","year":"2005","journal-title":"Science"}],"container-title":["PLoS Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pgen.1000468","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,19]],"date-time":"2019-05-19T22:57:34Z","timestamp":1558306654000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pgen.1000468"}},"subtitle":[],"editor":[{"given":"Jonathan","family":"Marchini","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2009,5,8]]},"references-count":37,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2009,5,8]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pgen.1000468","relation":{},"ISSN":["1553-7404"],"issn-type":[{"value":"1553-7404","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5,8]]}}}