{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T21:45:45Z","timestamp":1790459145778,"version":"4.1.0"},"reference-count":65,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2018,8,2]],"date-time":"2018-08-02T00:00:00Z","timestamp":1533168000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 CA014520"],"award-info":[{"award-number":["P30 CA014520"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HD075079"],"award-info":[{"award-number":["R01HD075079"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosgenetics.org"],"crossmark-restriction":false},"short-container-title":["PLoS Genet"],"DOI":"10.1371\/journal.pgen.1007488","type":"journal-article","created":{"date-parts":[[2018,8,2]],"date-time":"2018-08-02T17:28:07Z","timestamp":1533230887000},"page":"e1007488","update-policy":"https:\/\/doi.org\/10.1371\/journal.pgen.corrections_policy","source":"Crossref","is-referenced-by-count":38,"title":["Dynamic expression patterns of Irx3 and Irx5 during germline nest breakdown and primordial follicle formation promote follicle survival in mouse ovaries"],"prefix":"10.1371","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2010-1365","authenticated-orcid":true,"given":"Anqi","family":"Fu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5829-6789","authenticated-orcid":true,"given":"Sydney M.","family":"Oberholtzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3710-4797","authenticated-orcid":true,"given":"Stefan","family":"Bagheri-Fam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8513-1063","authenticated-orcid":true,"given":"Raphael H.","family":"Rastetter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Holdreith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5084-8929","authenticated-orcid":true,"given":"Valeria L.","family":"Caceres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7967-1864","authenticated-orcid":true,"given":"Steven V.","family":"John","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0875-7633","authenticated-orcid":true,"given":"Sarah A.","family":"Shaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4028-4779","authenticated-orcid":true,"given":"Kathleen J.","family":"Krentz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3286-7624","authenticated-orcid":true,"given":"Xiaoyun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7047-6694","authenticated-orcid":true,"given":"Chi-chung","family":"Hui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7757-4075","authenticated-orcid":true,"given":"Dagmar","family":"Wilhelm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5787-8856","authenticated-orcid":true,"given":"Joan S.","family":"Jorgensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2018,8,2]]},"reference":[{"issue":"1 Suppl Proceedings","key":"ref1","first-page":"S7","article-title":"Systemic adversities of ovarian failure","volume":"8","author":"AE Taylor","year":"2001","journal-title":"J Soc Gynecol Investig"},{"issue":"4","key":"ref2","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1093\/humupd\/dmi012","article-title":"Premature ovarian failure","volume":"11","author":"D Goswami","year":"2005","journal-title":"Hum Reprod Update"},{"issue":"12","key":"ref3","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1002\/mrd.22232","article-title":"Defining the neighborhoods that escort the oocyte through its early life events and into a functional follicle","volume":"80","author":"JS Jorgensen","year":"2013","journal-title":"Mol Reprod Dev"},{"issue":"3","key":"ref4","doi-asserted-by":"crossref","first-page":"R145","DOI":"10.1530\/JOE-14-0062","article-title":"Development of mammalian ovary","volume":"221","author":"P Smith","year":"2014","journal-title":"J Endocrinol"},{"issue":"12","key":"ref5","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1002\/dvg.20258","article-title":"From primordial germ cell to primordial follicle: mammalian female germ cell development","volume":"44","author":"ME Pepling","year":"2006","journal-title":"Genesis"},{"issue":"7","key":"ref6","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/s10815-011-9553-5","article-title":"Premature ovarian failure in nobox-deficient mice is caused by defects in somatic cell invasion and germ cell cyst breakdown","volume":"28","author":"A Lechowska","year":"2011","journal-title":"J Assist Reprod Genet"},{"issue":"17","key":"ref7","doi-asserted-by":"crossref","first-page":"3323","DOI":"10.1242\/dev.125.17.3323","article-title":"Female mouse germ cells form synchronously dividing cysts","volume":"125","author":"ME Pepling","year":"1998","journal-title":"Development"},{"issue":"5","key":"ref8","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1530\/REP-06-0270","article-title":"BAX regulates follicular endowment in mice","volume":"133","author":"CR Greenfeld","year":"2007","journal-title":"Reproduction"},{"issue":"8","key":"ref9","doi-asserted-by":"crossref","first-page":"3580","DOI":"10.1210\/en.2007-0088","article-title":"Estradiol, progesterone, and genistein inhibit oocyte nest breakdown and primordial follicle assembly in the neonatal mouse ovary in vitro and in vivo","volume":"148","author":"Y Chen","year":"2007","journal-title":"Endocrinology"},{"issue":"5687","key":"ref10","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1126\/science.1099755","article-title":"NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression","volume":"305","author":"A Rajkovic","year":"2004","journal-title":"Science"},{"issue":"2","key":"ref11","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1210\/en.2008-0213","article-title":"Suppression of Notch signaling in the neonatal mouse ovary decreases primordial follicle formation","volume":"150","author":"DJ Trombly","year":"2009","journal-title":"Endocrinology"},{"issue":"5","key":"ref12","doi-asserted-by":"crossref","first-page":"1968","DOI":"10.1210\/en.2006-1083","article-title":"Neonatal exposure to estrogens suppresses activin expression and signaling in the mouse ovary","volume":"148","author":"JL Kipp","year":"2007","journal-title":"Endocrinology"},{"issue":"12","key":"ref13","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1093\/molehr\/gap073","article-title":"The primordial pool of follicles and nest breakdown in mammalian ovaries","volume":"15","author":"C Tingen","year":"2009","journal-title":"Mol Hum Reprod"},{"issue":"10","key":"ref14","doi-asserted-by":"crossref","first-page":"e47238","DOI":"10.1371\/journal.pone.0047238","article-title":"Germ cells are not required to establish the female pathway in mouse fetal gonads","volume":"7","author":"DM Maatouk","year":"2012","journal-title":"PLoS One"},{"issue":"4","key":"ref15","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1139\/Y10-009","article-title":"Bidirectional communication between oocytes and follicle cells: ensuring oocyte developmental competence","volume":"88","author":"GM Kidder","year":"2010","journal-title":"Can J Physiol Pharmacol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/1477-7827-4-19","article-title":"Oocyte-granulosa cell interactions during mouse follicular development: regulation of kit ligand expression and its role in oocyte growth","volume":"4","author":"FH Thomas","year":"2006","journal-title":"Reprod Biol Endocrinol"},{"issue":"5576","key":"ref17","doi-asserted-by":"crossref","first-page":"2178","DOI":"10.1126\/science.1071965","article-title":"Intercellular communication in the mammalian ovary: oocytes carry the conversation","volume":"296","author":"MM Matzuk","year":"2002","journal-title":"Science"},{"issue":"3","key":"ref18","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/nrm3531","article-title":"The road to maturation: somatic cell interaction and self-organization of the mammalian oocyte","volume":"14","author":"R Li","year":"2013","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"12","key":"ref19","doi-asserted-by":"crossref","first-page":"8060","DOI":"10.1073\/pnas.122066899","article-title":"A negative feedback system between oocyte bone morphogenetic protein 15 and granulosa cell kit ligand: its role in regulating granulosa cell mitosis","volume":"99","author":"F Otsuka","year":"2002","journal-title":"Proceedings of the National Academy of Sciences"},{"issue":"1","key":"ref20","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1210\/endo-120-1-198","article-title":"Gonadotropins and estradiol stimulate immunoreactive insulin-like growth factor-I production by porcine granulosa cells in vitro","volume":"120","author":"C-J Hsu","year":"1987","journal-title":"Endocrinology"},{"issue":"4","key":"ref21","doi-asserted-by":"crossref","first-page":"2184","DOI":"10.1210\/endo-126-4-2184","article-title":"Insulin-Like Growth Factor-Binding Protein (IGF-BP) Inhibition of Granulosa Cell Function: Effect on Cyclic Adenosine 3\u20195\u2019-Monophosphate, Deoxyribonucleic Acid Synthesis, and Comparison with the Effect of an IGF-I Antibody","volume":"126","author":"TA Bicsak","year":"1990","journal-title":"Endocrinology"},{"issue":"18","key":"ref22","doi-asserted-by":"crossref","first-page":"5694","DOI":"10.1016\/S0021-9258(17)33113-7","article-title":"Studies on the role of plasminogen activator in ovulation. In vitro response of granulosa cells to gonadotropins, cyclic nucleotides, and prostaglandins","volume":"251","author":"S Strickland","year":"1976","journal-title":"Journal of Biological Chemistry"},{"issue":"5","key":"ref23","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1095\/biolreprod.110.088559","article-title":"The fused toes locus is essential for somatic-germ cell interactions that foster germ cell maturation in developing gonads in mice","volume":"84","author":"B Kim","year":"2011","journal-title":"Biol Reprod"},{"issue":"4","key":"ref24","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0959-437X(02)00317-9","article-title":"Iroquois genes: genomic organization and function in vertebrate neural development","volume":"12","author":"JL Gomez-Skarmeta","year":"2002","journal-title":"Curr Opin Genet Dev"},{"issue":"15","key":"ref25","doi-asserted-by":"crossref","first-page":"2847","DOI":"10.1242\/dev.128.15.2847","article-title":"The Iroquois family of genes: from body building to neural patterning","volume":"128","author":"F Cavodeassi","year":"2001","journal-title":"Development"},{"issue":"10","key":"ref26","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1101\/gr.144100","article-title":"Organization of mouse Iroquois homeobox genes in two clusters suggests a conserved regulation and function in vertebrate development","volume":"10","author":"T Peters","year":"2000","journal-title":"Genome Res"},{"issue":"1\u20132","key":"ref27","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0925-4773(01)00451-8","article-title":"Gene and cluster-specific expression of the Iroquois family members during mouse development","volume":"107","author":"AC Houweling","year":"2001","journal-title":"Mech Dev"},{"issue":"6","key":"ref28","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.modgep.2005.04.011","article-title":"Irx3 is differentially up-regulated in female gonads during sex determination","volume":"5","author":"JS Jorgensen","year":"2005","journal-title":"Gene Expr Patterns"},{"issue":"2","key":"ref29","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.ydbio.2010.10.010","article-title":"Primordial germ cell proliferation is impaired in Fused Toes mutant embryos","volume":"349","author":"B Kim","year":"2011","journal-title":"Dev Biol"},{"issue":"7","key":"ref30","doi-asserted-by":"crossref","first-page":"e41683","DOI":"10.1371\/journal.pone.0041683","article-title":"Identification of novel markers of mouse fetal ovary development","volume":"7","author":"H Chen","year":"2012","journal-title":"PLoS One"},{"issue":"3","key":"ref31","doi-asserted-by":"crossref","first-page":"e1002575","DOI":"10.1371\/journal.pgen.1002575","article-title":"Temporal transcriptional profiling of somatic and germ cells reveals biased lineage priming of sexual fate in the fetal mouse gonad","volume":"8","author":"SA Jameson","year":"2012","journal-title":"PLoS genetics"},{"issue":"21","key":"ref32","doi-asserted-by":"crossref","first-page":"4007","DOI":"10.1242\/dev.081703","article-title":"Cooperative and antagonistic roles for Irx3 and Irx5 in cardiac morphogenesis and postnatal physiology","volume":"139","author":"N Gaborit","year":"2012","journal-title":"Development"},{"issue":"2","key":"ref33","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.devcel.2014.03.001","article-title":"Formation of proximal and anterior limb skeleton requires early function of Irx3 and Irx5 and is negatively regulated by Shh signaling","volume":"29","author":"D Li","year":"2014","journal-title":"Dev Cell"},{"issue":"4","key":"ref34","first-page":"471","article-title":"Superovulation strategies for 6 commonly used mouse strains","volume":"50","author":"C Luo","year":"2011","journal-title":"Journal of the American Association for Laboratory Animal Science"},{"issue":"7492","key":"ref35","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1038\/nature13138","article-title":"Obesity-associated variants within FTO form long-range functional connections with IRX3","volume":"507","author":"S Smemo","year":"2014","journal-title":"Nature"},{"issue":"1","key":"ref36","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.ydbio.2005.08.029","article-title":"The Iroquois homeobox gene, Irx5, is required for retinal cone bipolar cell development","volume":"287","author":"CW Cheng","year":"2005","journal-title":"Developmental biology"},{"issue":"33","key":"ref37","doi-asserted-by":"crossref","first-page":"13576","DOI":"10.1073\/pnas.1106911108","article-title":"Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network","volume":"108","author":"SS Zhang","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"10","key":"ref38","doi-asserted-by":"crossref","first-page":"3636","DOI":"10.1128\/MCB.23.10.3636-3645.2003","article-title":"Nonmuscle myosin promotes cytoplasmic localization of PBX","volume":"23","author":"H Huang","year":"2003","journal-title":"Mol Cell Biol"},{"issue":"47","key":"ref39","doi-asserted-by":"crossref","first-page":"49384","DOI":"10.1074\/jbc.M406046200","article-title":"Subcellular localization of multiple PREP2 isoforms is regulated by actin, tubulin, and nuclear export","volume":"279","author":"K Haller","year":"2004","journal-title":"J Biol Chem"},{"issue":"2","key":"ref40","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.yjmcc.2005.11.002","article-title":"Regional variation in mRNA transcript abundance within the ventricular wall","volume":"40","author":"B Rosati","year":"2006","journal-title":"J Mol Cell Cardiol"},{"issue":"2","key":"ref41","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.ydbio.2014.08.013","article-title":"Marker genes identify three somatic cell types in the fetal mouse ovary","volume":"394","author":"RH Rastetter","year":"2014","journal-title":"Dev Biol"},{"key":"ref42","first-page":"343","article-title":"Roles of extracellular matrix in follicular development. Journal of reproduction and fertility","volume":"54","author":"R Rodgers","year":"1999","journal-title":"Supplement"},{"issue":"3","key":"ref43","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/BF00318878","article-title":"Basal lamina and other extracellular matrix produced by bovine granulosa cells in anchorage-independent culture","volume":"282","author":"H Rodgers","year":"1995","journal-title":"Cell and tissue research"},{"issue":"8 Suppl","key":"ref44","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1177\/1933719107309818","article-title":"The role of the extracellular matrix in ovarian follicle development","volume":"14","author":"TK Woodruff","year":"2007","journal-title":"Reprod Sci"},{"issue":"5","key":"ref45","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1530\/rep.0.1230613","article-title":"Gap junctions and ovarian folliculogenesis","volume":"123","author":"GM Kidder","year":"2002","journal-title":"Reproduction"},{"issue":"2","key":"ref46","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1006\/dbio.2001.0216","article-title":"Intercellular communication via connexin43 gap junctions is required for ovarian folliculogenesis in the mouse","volume":"233","author":"CL Ackert","year":"2001","journal-title":"Developmental biology"},{"issue":"1\u20132","key":"ref47","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1080\/15419060600631748","article-title":"Cx37 and Cx43 localize to zona pellucida in mouse ovarian follicles","volume":"13","author":"AM Simon","year":"2006","journal-title":"Cell communication & adhesion"},{"issue":"2","key":"ref48","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1095\/biolreprod.111.095208","article-title":"Temporal differences in granulosa cell specification in the ovary reflect distinct follicle fates in mice","volume":"86","author":"L Mork","year":"2012","journal-title":"Biol Reprod"},{"issue":"3","key":"ref49","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1095\/biolreprod47.3.466","article-title":"Heterogeneity of cell populations that contribute to the formation of primordial follicles in rats","volume":"47","author":"AN Hirshfield","year":"1992","journal-title":"Biology of reproduction"},{"issue":"4","key":"ref50","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1093\/molehr\/gau007","article-title":"The two classes of primordial follicles in the mouse ovary: their development, physiological functions and implications for future research","volume":"20","author":"W Zheng","year":"2014","journal-title":"Mol Hum Reprod"},{"issue":"4","key":"ref51","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1093\/hmg\/ddt486","article-title":"Two classes of ovarian primordial follicles exhibit distinct developmental dynamics and physiological functions","volume":"23","author":"W Zheng","year":"2013","journal-title":"Human molecular genetics"},{"issue":"8","key":"ref52","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1038\/ncb3000","article-title":"Lgr5 marks stem\/progenitor cells in ovary and tubal epithelia","volume":"16","author":"A Ng","year":"2014","journal-title":"Nat Cell Biol"},{"issue":"8","key":"ref53","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1038\/ncb3020","article-title":"Ovarian epithelium regeneration by Lgr5(+) cells","volume":"16","author":"B Capel","year":"2014","journal-title":"Nat Cell Biol"},{"issue":"2","key":"ref54","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1006\/dbio.2000.9801","article-title":"Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart","volume":"224","author":"VM Christoffels","year":"2000","journal-title":"Dev Biol"},{"issue":"1","key":"ref55","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0925-4773(97)00165-2","article-title":"Identification of the vertebrate Iroquois homeobox gene family with overlapping expression during early development of the nervous system","volume":"69","author":"A Bosse","year":"1997","journal-title":"Mechanisms of development"},{"issue":"6","key":"ref56","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1210\/mend.15.6.0662","article-title":"Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function","volume":"15","author":"C Yan","year":"2001","journal-title":"Molecular Endocrinology"},{"issue":"1","key":"ref57","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/mrd.21265","article-title":"Integral role of GDF-9 and BMP-15 in ovarian function","volume":"78","author":"F Otsuka","year":"2011","journal-title":"Molecular reproduction and development"},{"issue":"5","key":"ref58","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.biomaterials.2005.06.016","article-title":"The in vitro regulation of ovarian follicle development using alginate-extracellular matrix gels","volume":"27","author":"PK Kreeger","year":"2006","journal-title":"Biomaterials"},{"issue":"5","key":"ref59","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1177\/31.5.6341456","article-title":"Developmental changes in the ovarian follicular basal lamina detected by immunofluorescence and electron microscopy","volume":"31","author":"P Bagavandoss","year":"1983","journal-title":"Journal of Histochemistry & Cytochemistry"},{"issue":"1","key":"ref60","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1530\/jrf.0.1040115","article-title":"Gene expression and protein distribution of collagen, fibronectin and laminin in bovine follicles and corpora lutea","volume":"104","author":"Y Zhao","year":"1995","journal-title":"Journal of reproduction and fertility"},{"issue":"1","key":"ref61","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0303-7207(02)00057-6","article-title":"Extracellular matrix of the bovine ovarian membrana granulosa","volume":"191","author":"R Rodgers","year":"2002","journal-title":"Molecular and cellular endocrinology"},{"issue":"5","key":"ref62","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/s00418-006-0194-1","article-title":"Distribution of extracellular matrix proteins type I collagen, type IV collagen, fibronectin, and laminin in mouse folliculogenesis","volume":"126","author":"CB Berkholtz","year":"2006","journal-title":"Histochem Cell Biol"},{"issue":"2","key":"ref63","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.ydbio.2014.12.024","article-title":"Oocyte glycoproteins regulate the form and function of the follicle basal lamina and theca cells","volume":"401","author":"AP Christensen","year":"2015","journal-title":"Dev Biol"},{"issue":"4","key":"ref64","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1096\/fj.13-233247","article-title":"Wnt4, a pleiotropic signal for controlling cell polarity, basement membrane integrity, and antim\u00fcllerian hormone expression during oocyte maturation in the female follicle","volume":"28","author":"R Prunskaite-Hyyryl\u00e4inen","year":"2014","journal-title":"The FASEB Journal"},{"issue":"5\u20136","key":"ref65","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.mod.2009.02.006","article-title":"Antagonism of the testis- and ovary-determining pathways during ovotestis development in mice","volume":"126","author":"D Wilhelm","year":"2009","journal-title":"Mech Dev"}],"container-title":["PLOS Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pgen.1007488","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,28]],"date-time":"2022-08-28T17:39:57Z","timestamp":1661708397000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pgen.1007488"}},"subtitle":[],"editor":[{"given":"Paula E.","family":"Cohen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2018,8,2]]},"references-count":65,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2018,8,2]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pgen.1007488","relation":{},"ISSN":["1553-7404"],"issn-type":[{"value":"1553-7404","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,2]]}}}