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A tutorial on how (not) to over-interpret STRUCTURE\/ADMIXTURE bar plots [Internet]. bioRxiv. 2018. p. 066431. 10.1101\/066431","DOI":"10.1101\/066431"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nmeth.1785","article-title":"A linear complexity phasing method for thousands of genomes","volume":"9","author":"O Delaneau","year":"2011","journal-title":"Nat Methods"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"e1002453","DOI":"10.1371\/journal.pgen.1002453","article-title":"Inference of population structure using dense haplotype data","volume":"8","author":"DJ Lawson","year":"2012","journal-title":"PLoS Genet"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1126\/science.1243518","article-title":"A genetic atlas of human admixture history","volume":"343","author":"G Hellenthal","year":"2014","journal-title":"Science"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1534\/genetics.112.145037","article-title":"Ancient admixture in human history","volume":"192","author":"N Patterson","year":"2012","journal-title":"Genetics"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1038\/nature06250","article-title":"Genome-wide detection and characterization of positive selection in human populations","volume":"449","author":"PC Sabeti","year":"2007","journal-title":"Nature"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"e72","DOI":"10.1371\/journal.pbio.0040072","article-title":"A map of recent positive selection in the human genome","volume":"4","author":"BF Voight","year":"2006","journal-title":"PLoS Biol"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1093\/bioinformatics\/bts115","article-title":"rehh: an R package to detect footprints of selection in genome-wide SNP data from haplotype structure","volume":"28","author":"M Gautier","year":"2012","journal-title":"Bioinformatics"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1534\/genetics.112.144071","article-title":"Limited evidence for classic selective sweeps in African populations","volume":"192","author":"JM Granka","year":"2012","journal-title":"Genetics"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1038\/nprot.2015.105","article-title":"Genomic variant annotation and prioritization with ANNOVAR and wANNOVAR","volume":"10","author":"H Yang","year":"2015","journal-title":"Nat Protoc"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nature18964","article-title":"The Simons Genome Diversity Project: 300 genomes from 142 diverse populations","volume":"538","author":"S Mallick","year":"2016","journal-title":"Nature"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1093\/bioinformatics\/18.2.337","article-title":"Generating samples under a Wright-Fisher neutral model of genetic variation","volume":"18","author":"RR Hudson","year":"2002","journal-title":"Bioinformatics"}],"updated-by":[{"DOI":"10.1371\/journal.pgen.1008027","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2019,3,20]],"date-time":"2019-03-20T00:00:00Z","timestamp":1553040000000}}],"container-title":["PLOS Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pgen.1008027","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T15:32:26Z","timestamp":1663083146000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pgen.1008027"}},"subtitle":[],"editor":[{"given":"Jun Z","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2019,3,8]]},"references-count":76,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,3,8]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pgen.1008027","relation":{"new_version":[{"id-type":"doi","id":"10.1371\/journal.pgen.1008027","asserted-by":"object"}]},"ISSN":["1553-7404"],"issn-type":[{"value":"1553-7404","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,8]]}}}