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To better understand the mechanisms that pattern and shape these structures, we focus on development of collagen-rich cuticle ridges (alae) in adult\n                    <jats:italic>C. elegans<\/jats:italic>\n                    . Previous studies suggested that longitudinal actin filament bundles (AFBs) in the lateral seam epidermis specify alae position through a mechanism that involves post-secretory matrix delamination. Here we identify additional components of this highly organized cortical actin network and show that loss of the apical \u03b2H-spectrin SMA-1 specifically disrupts organization of the two AFBs that would normally flank the site where the middle alae ridge forms. Correspondingly,\n                    <jats:italic>sma-1<\/jats:italic>\n                    loss, or mutation of its actin binding domains, also disrupts formation of the middle alae ridge. Ultrastructurally,\n                    <jats:italic>sma-1<\/jats:italic>\n                    mutants have expanded regions of matrix delamination that can explain middle ridge loss. Together, these data highlight the importance of apical spectrin for organizing a patterned actin network within epithelia and show that, via its effects on actin organization, spectrin can also change the extracellular matrix and its patterns on animal surfaces.\n                  <\/jats:p>","DOI":"10.1371\/journal.pgen.1012236","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T17:48:28Z","timestamp":1784224108000},"page":"e1012236","update-policy":"https:\/\/doi.org\/10.1371\/journal.pgen.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Apical spectrin organizes cortical actin filament bundles to pattern C. elegans cuticle ridges"],"prefix":"10.1371","volume":"22","author":[{"given":"Prioty Ferheen","family":"Sarwar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0854-241X","authenticated-orcid":true,"given":"Trevor 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