{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T12:45:19Z","timestamp":1794660319942,"version":"4.9.1"},"reference-count":120,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T00:00:00Z","timestamp":1664409600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"British Columbia Immunization Committee"},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["151944"],"award-info":[{"award-number":["151944"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011094","name":"Public Health Agency of Canada","doi-asserted-by":"crossref","award":["151944"],"award-info":[{"award-number":["151944"]}],"id":[{"id":"10.13039\/100011094","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plosglobalpublichealth.org"],"crossmark-restriction":false},"short-container-title":["PLOS Glob Public Health"],"abstract":"<jats:p>Adolescence presents a key opportunity to build vaccine-related health literacy and promote vaccine confidence and uptake. Although adolescents are central to vaccination programs, their views around vaccines are frequently underrepresented in qualitative literature. We reviewed qualitative studies to systematically identify and summarize existing evidence on adolescents\u2019 own understanding of vaccines and experiences with vaccine decision-making, including self-consent when applicable. CINAHL; Embase; Ovid Medline; and Psych Info database searches were last updated on May 28, 2022. Data pertaining to general study characteristics, participant demographics, and qualitative content were extracted independently by two reviewers and analyzed using textual narrative synthesis. Out of 3559 individual records, 59 studies were included. The majority of the studies were conducted in high-income countries and 75% focused on human papilloma virus vaccines, with the remaining studies looking at COVID-19, meningococcal, hepatitis B and influenza vaccines or adolescent experiences with vaccines in general. Adolescent self-consent was explored in 7 studies. Perspectives from sexual and gender minorities were lacking across studies. Adolescents often had limited understanding of different vaccines and commonly perceived vaccine information to be directed towards their parents rather than themselves. Many adolescents felt school-based vaccine education and information available through healthcare providers were insufficient to make informed decisions about vaccines. While adolescents described obtaining vaccine information from traditional and online media, face-to-face interactions and opinions from trusted adults remained important. Adolescents generally relied on their parents for vaccine-decision making, even when self-consent was an option. A notable exception to this included marginalized adolescents who could not rely on parents for health-related advice. Qualitative literature about adolescent vaccines would be enriched by studies examining vaccines other than the HPV vaccine, studies examining adolescent vaccine programs in low and middle-income countries, and by deliberately eliciting vaccine experiences of adolescent with diverse sexual orientation and gender identities.<\/jats:p>","DOI":"10.1371\/journal.pgph.0001109","type":"journal-article","created":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T18:53:27Z","timestamp":1664477607000},"page":"e0001109","update-policy":"https:\/\/doi.org\/10.1371\/journal.pgph.corrections_policy","source":"Crossref","is-referenced-by-count":35,"title":["What do adolescents think about vaccines? Systematic review of qualitative studies"],"prefix":"10.1371","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6324-0779","authenticated-orcid":true,"given":"Hana","family":"Mitchell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5130-8812","authenticated-orcid":true,"given":"Rebecca","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7895-2461","authenticated-orcid":true,"given":"Prubjot K.","family":"Gill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4738-8711","authenticated-orcid":true,"given":"Joban","family":"Dhanoa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c8ve","family":"Dub\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2118-4174","authenticated-orcid":true,"given":"Julie A.","family":"Bettinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2022,9,29]]},"reference":[{"issue":"3","key":"pgph.0001109.ref001","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1001\/archpedi.161.3.252","article-title":"National Health Care Visit Patterns of Adolescents: Implications for Delivery of New Adolescent Vaccines.","volume":"161","author":"CM Rand","year":"2007","journal-title":"Arch Pediatr Adolesc Med."},{"issue":"5","key":"pgph.0001109.ref002","doi-asserted-by":"crossref","first-page":"130","DOI":"10.15585\/mmwr.mm6905a3","article-title":"Advisory Committee on Immunization Practices Recommended Immunization Schedule for Children and Adolescents Aged 18 Years or Younger\u2014United States, 2020.","volume":"69","author":"CL Robinson","year":"2020","journal-title":"MMWR Morb Mortal Wkly Rep."},{"key":"pgph.0001109.ref003","unstructured":"World Health Organization. WHO recommendations for routine immunization\u2014summary tables [Internet]. 2020 [cited 2020 Oct 10]. 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Korioth","year":"2020","journal-title":"Am Acad Pediatr News."},{"issue":"4","key":"pgph.0001109.ref008","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1080\/14760584.2018.1456921","article-title":"Educating children and adolescents about vaccines: a review of current literature.","volume":"17","author":"AR Maisonneuve","year":"2018","journal-title":"Expert Rev Vaccines"},{"issue":"1","key":"pgph.0001109.ref009","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jadohealth.2010.10.004","article-title":"Partnerships Between Parents and Health Care Professionals to Improve Adolescent Health.","volume":"49","author":"CA Ford","year":"2011","journal-title":"J Adolesc Health"},{"key":"pgph.0001109.ref010","unstructured":"World Health Organization. Adolescent Health [Internet]. 2021 [cited 2021 Feb 21]. Available from: https:\/\/www.who.int\/westernpacific\/health-topics\/adolescent-health"},{"key":"pgph.0001109.ref011","unstructured":"UN General Assembly. 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An Exploration of Italian Children\u2019s Knowledge and Perceptions About the HPV Vaccine","author":"A. Occa","year":"2020","journal-title":"J Cancer Educ Off J Am Assoc Cancer Educ"},{"issue":"1","key":"pgph.0001109.ref039","doi-asserted-by":"crossref","first-page":"216","DOI":"10.4161\/hv.26332","article-title":"Focusing on flu. 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