{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T02:23:02Z","timestamp":1785637382074,"version":"3.56.0"},"reference-count":54,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T00:00:00Z","timestamp":1672272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["SFRH\/BD\/117037\/2016"],"award-info":[{"award-number":["SFRH\/BD\/117037\/2016"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosglobalpublichealth.org"],"crossmark-restriction":false},"short-container-title":["PLOS Glob Public Health"],"abstract":"<jats:p>Newborn mortality and adverse birth outcomes (ABOs) in Sao Tome &amp; Pr\u00edncipe (STP) are overwhelmingly high, and access to quality-antenatal care (ANC) is one of the strategies to tackle it. This study aimed to fill the gaps in ANC screenings with a focus on how to improve neonatal outcomes. We conducted a retrospective hospital-based study in which ANC pregnancy cards were reviewed. Screenings were described and compared according to the total number of ANC contacts: 1\u20133 (inadequate), 4\u20137 (adequate), and \u22658 (complete). The collected data were entered into QuickTapSurvey and exported to SPSS version 25 for analysis. Statistical significance was considered at a p-value \u22640.05. A total of 511 ANC pregnancy cards were reviewed. Mothers\u2019 mean age was 26.6 (SD = 7.1), 51.7% had a first trimester early booking, 14.9% (76) had 1\u20133 ANC contacts, 46.4% (237) had 4\u20137 and 38.7% (198) \u22658. Screening absence was found in 24%-41%, lack of money was registered in 36%. Pregnant women had no screening performed for HIV in 4.5%, syphilis in 8.8%, HBV 39.3%, malaria 25.8%, hemoglobin 24.5%, blood glucose 45.4%, urine 29.7%, stool exams 27.8% and 41.1% had no ultrasound. Screening completion for blood group, HIV, malaria, urine, hemoglobin, and coproparasitological exam were found to have a statistically significant difference (p&lt;0.001) for the complete ANC group when compared to other groups. Antenatal problems identified were: 1) bacteriuria (43.2%); 2) maternal anemia (37%); 3) intestinal parasitic infections (59.2%); 4) sickle cell solubility test positive (13%); and 5) a RhD-negative phenotype (5.8%). Missed-ANC treatments were up to 50%. This study reveals a coverage-quality gap in STP since no pregnant woman is left without ANC contact, although most still miss evidence-based screenings with an impact on neonatal outcomes. Strategies such as implementing a total free ANC screening package in STP would enhance maternal diagnosis and prompt treatments.<\/jats:p>","DOI":"10.1371\/journal.pgph.0001444","type":"journal-article","created":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T18:24:10Z","timestamp":1672338250000},"page":"e0001444","update-policy":"https:\/\/doi.org\/10.1371\/journal.pgph.corrections_policy","source":"Crossref","is-referenced-by-count":15,"title":["Antenatal screenings and maternal diagnosis among pregnant women in Sao Tome &amp; Principe\u2014Missed opportunities to improve neonatal health: A hospital-based study"],"prefix":"10.1371","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8042-0846","authenticated-orcid":true,"given":"Alexandra","family":"Vasconcelos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7954-6393","authenticated-orcid":true,"given":"Swasilanne","family":"Sousa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelson","family":"Bandeira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7421-8550","authenticated-orcid":true,"given":"Marta","family":"Alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2918-8364","authenticated-orcid":true,"given":"Ana Lu\u00edsa","family":"Papoila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filomena","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria C\u00e9u","family":"Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2022,12,29]]},"reference":[{"key":"pgph.0001444.ref001","volume-title":"Antenatal care in developing countries: Promises achievements and missed opportunities: An analysis of trends, level and differentials","author":"CL Abou-Zahr","year":"2003"},{"issue":"1","key":"pgph.0001444.ref002","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1186\/s12913-019-4130-1","article-title":"Examining the impact of WHO\u2019s Focused Antenatal Care policy on early access, underutilisation and quality of antenatal care services in Malawi: a retrospective study","volume":"19","author":"M Mchenga","year":"2019","journal-title":"BMC Health Serv Res"},{"key":"pgph.0001444.ref003","first-page":"2015","article-title":"Alternative versus standard packages of antenatal care for low-risk pregnancy","author":"T Dowswell","year":"2015","journal-title":"Cochrane Libr"},{"key":"pgph.0001444.ref004","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2018\/1673517","article-title":"Determinants of antenatal healthcare utilisation by pregnant women in third trimester in Peri-urban Ghana","volume":"2018","author":"JA Akowuah","year":"2018","journal-title":"J Trop Med"},{"issue":"1","key":"pgph.0001444.ref005","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1080\/07399332.2016.1225743","article-title":"Wealth and antenatal care utilization in Nigeria: Policy implications","volume":"38","author":"AF Fagbamigbe","year":"2017","journal-title":"Health Care Women Int"},{"key":"pgph.0001444.ref006","volume-title":"WHO Recommendations on Antenatal Care for a Positive Pregnancy Experience","author":"World Health Organization"},{"key":"pgph.0001444.ref007","volume-title":"WHO antenatal care randomized trial: manual for the implementation of the new model","author":"World Health Organization","year":"2002"},{"key":"pgph.0001444.ref008","doi-asserted-by":"crossref","first-page":"6696829","DOI":"10.1155\/2021\/6696829","article-title":"Noncompliance with the WHO\u2019s recommended eight antenatal care visits among pregnant women in sub-Saharan Africa: A multilevel analysis","volume":"2021","author":"EK Odusina","year":"2021","journal-title":"Biomed Res Int"},{"key":"pgph.0001444.ref009","first-page":"55","article-title":"Antenatal care. 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