{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T11:07:29Z","timestamp":1783163249688,"version":"3.54.6"},"reference-count":41,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2024,1,5]],"date-time":"2024-01-05T00:00:00Z","timestamp":1704412800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosglobalpublichealth.org"],"crossmark-restriction":false},"short-container-title":["PLOS Glob Public Health"],"abstract":"<jats:p>Pre-eclampsia or eclampsia is a serious reproductive health problem which can cause maternal, fetal and neonatal morbidity and mortality worldwide. However till the notable reasons of it is not very clear at all. The main essence of the present study was to examine the association between dietary intake, iron and folic acid consumption during pregnancy and the chances of occurrences of pre-eclampsia or eclampsia among Indian women. A cross sectional observational study was performed by using NFHS-5 (2019\u201321) data. 190,797 ever married women aged between 15\u201349 years who had a live birth in the past five years preceding the survey were availed for this study. Multivariable logistic regression analysis was carried out to find out the association between dietary and supplementary intake and occurrences of eclampsia. About 3.6% of the sample women had pre-eclampsia or eclampsia. The results of the study indicated that the likelihood of the prevalence of pre-eclampsia or eclampsia was significantly higher among those women who did not take adequate diet and as well as not consumed iron and folic acid tablet or syrup for at least 90 days during pregnancy compared to those women who took adequate diet and iron and folic acid supplementation even after controlling some maternal, health and lifestyle, socio-economic and demographic characteristics. Integrated and quality ANC services can only ensure adequate nutritional intake in terms of healthy and balanced diet. So, quality ANC services and with this micronutrients intake could be an effective way to reduce the prevalence of pre-eclampsia or eclampsia.<\/jats:p>","DOI":"10.1371\/journal.pgph.0001633","type":"journal-article","created":{"date-parts":[[2024,1,5]],"date-time":"2024-01-05T18:21:42Z","timestamp":1704478902000},"page":"e0001633","update-policy":"https:\/\/doi.org\/10.1371\/journal.pgph.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["An association of deficiencies in balanced dietary practices and inadequate iron and folic acid supplement\u2019s intake during pregnancy and increasing risk of pre-eclampsia or eclampsia among Indian women"],"prefix":"10.1371","volume":"4","author":[{"given":"Priya","family":"Das","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanu","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Partha","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3256-8904","authenticated-orcid":true,"given":"TamalBasu","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,1,5]]},"reference":[{"key":"pgph.0001633.ref001","unstructured":"World Health Organization. WHO recommendations for prevention and treatment of pre-eclampsia and eclampsia."},{"issue":"6","key":"pgph.0001633.ref002","doi-asserted-by":"crossref","first-page":"2","DOI":"10.4172\/2325-9795.1000169","article-title":"Prevalence and risk factors for pre-eclampsia in Indian women: a national cross sectional study","volume":"3","author":"S Agrawal","year":"2014","journal-title":"J Womens Health"},{"issue":"1","key":"pgph.0001633.ref003","doi-asserted-by":"crossref","first-page":"3","DOI":"10.3390\/jcdd5010003","article-title":"Pre-eclampsia and eclampsia: An update on the pharmacological treatment applied in Portugal","volume":"5","author":"GM Peres","year":"2018","journal-title":"Journal of cardiovascular development and disease"},{"issue":"4","key":"pgph.0001633.ref004","doi-asserted-by":"crossref","first-page":"959","DOI":"10.3390\/cells10040959","article-title":"PROVE\u2014pre-eclampsia obstetric adverse events: establishment of a biobank and database for 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