{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T02:23:21Z","timestamp":1792981401066,"version":"4.5.0"},"reference-count":19,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T00:00:00Z","timestamp":1752451200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosglobalpublichealth.org"],"crossmark-restriction":false},"short-container-title":["PLOS Glob Public Health"],"abstract":"<jats:p>Chorioamnionitis is a medical illness marked by maternal fever, leukocytosis, tachycardia, uterine discomfort, and preterm membrane rupture. Chorioamnionitis affects approximately 4% of full-term deliveries worldwide, but it is more common in preterm pregnancies and early membrane rupture. This study aimed to assess the prevalence and associated factors of chorioamnionitis among mothers in public hospitals in Addis Ababa, Ethiopia.A hospital-based cross-sectional study was conducted among maternity patients at Zewditu Memorial, Gandhi Memorial, and Abebech Gobena MCH Hospitals from June 15 to July 15, 2024. A simple random sampling technique with proportional size allocation was used to select a total sample of 379 patients. Data were collected using an interviewer-administered questionnaire and analyzed with SPSS version 26.Binary logistic regression was used to analyze the association between dependent and independent variables. Significance was set at p\u2009&lt;\u20090.05 with a 95% confidence interval, and data were presented in tables and graphs.A total number of 356 patient\u2019s data were analysed and the proportion of patients with Chorioamnionitis was found to be 21.3%. After adjustment for possible confounders on multi-variable binary logistic regression analysis age\u2009&lt;\u200925 years [AOR\u2009=\u20090.26, 95% CI (0.09-0.72)], having premature rupture of membrane [AOR\u2009=\u20092.24, 95% CI (1.05-4.78)], duration of labor\u2009&lt;\u200912 hour [AOR\u2009=\u20090.10, 95% CI (0.04-0.24)], and having urinary tract infection [AOR\u2009=\u20093.54, 95% CI (1.72-7.27)] were the significant variable associated with Chorioamnionitis. Chorioamnionitis is a common complication in maternity patients. The magnitude of Chorioamnionitis in the selected public hospital was 21.3%. Age, premature rupture of membrane, duration of labor and urinary tract infection were the factors that had significant association with Chorioamnionitis. The Ministry of Health should focus on creating strategies to prevent and intervene in Chorioamnionitis for patients with premature rupture of membranes and prolonged labor.<\/jats:p>","DOI":"10.1371\/journal.pgph.0004467","type":"journal-article","created":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T17:24:45Z","timestamp":1752513885000},"page":"e0004467","update-policy":"https:\/\/doi.org\/10.1371\/journal.pgph.corrections_policy","source":"Crossref","is-referenced-by-count":5,"title":["Chorioamnionitis and its associated factors among women admitted to the maternity unit of Public Hospitals in Addis Ababa, Ethiopia"],"prefix":"10.1371","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2476-5959","authenticated-orcid":true,"given":"Tadios Niguss","family":"Derese","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mekdes Dereje","family":"Wondafrash","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8388-0880","authenticated-orcid":true,"given":"Abel Melese","family":"Teka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0334-3387","authenticated-orcid":true,"given":"Hiwot Soboksa","family":"Mideksa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidia Dagne","family":"Mario","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-7871-0569","authenticated-orcid":true,"given":"Tsegaye Gebreyes","family":"Hundie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robel Bayou","family":"Tilahun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abel Abebe","family":"Demie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,7,14]]},"reference":[{"issue":"2","key":"pgph.0004467.ref001","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.clp.2010.02.003","article-title":"Diagnosis and management of clinical chorioamnionitis","volume":"37","author":"ATN Tita","year":"2010","journal-title":"Clin Perinatol"},{"issue":"2","key":"pgph.0004467.ref002","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1053\/hupa.2002.31291","article-title":"Re-evaluation of chorioamnionitis and funisitis with a special reference to subacute chorioamnionitis","volume":"33","author":"M Ohyama","year":"2002","journal-title":"Hum 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infection","volume":"36","author":"ER Newton","year":"1993","journal-title":"Clin Obstet Gynecol"},{"issue":"20","key":"pgph.0004467.ref010","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1056\/NEJM200005183422007","article-title":"Intrauterine infection and preterm delivery","volume":"342","author":"RL Goldenberg","year":"2000","journal-title":"N Engl J Med"},{"issue":"1","key":"pgph.0004467.ref011","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.ajog.2005.06.081","article-title":"Acute and chronic chorioamnionitis and the risk of perinatal human immunodeficiency virus-1 transmission","volume":"194","author":"BH Chi","year":"2006","journal-title":"Am J Obstet Gynecol"},{"key":"pgph.0004467.ref012","article-title":"Prevalence and factors associated with histological chorioamnionitis among term women delivering from Mbarara regional referral hospital","author":"J Njagi","year":"2016","journal-title":"Journal of Health, Medicine and 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Cristal XimenaGallego-Betancourt, Prevalence of histologic Chorioamnionitis in patients with spontaneous pre-term labour in Popay\u00e1n, Colombia, 2014-2016."},{"issue":"4","key":"pgph.0004467.ref015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0215058","article-title":"The prevalence of histologic acute chorioamnionitis among HIV infected pregnant women in Uganda and its association with adverse birth outcomes","volume":"14","author":"J Ategeka","year":"2019","journal-title":"PLoS One"},{"issue":"1","key":"pgph.0004467.ref016","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3329\/bjog.v26i1.13752","article-title":"The Incidence, Risk Factors and Common Foetal outcome of Chorioamnionitis in Women with Preterm Premature Rupture of Membrane (PPROM): A Single Centre Study","volume":"26","author":"NS Afza","year":"2013","journal-title":"Bangladesh J Obstet Gynaecol"},{"issue":"3","key":"pgph.0004467.ref017","first-page":"60","article-title":"The prevalence and management outcome of pregnant mothers with chorioamnionitis in Mekane Salem Primary Hospital, Ethiopia, 2019.","volume":"1","author":"IR Augustin","year":"2020","journal-title":"Universe Int J Interdiscip Res"},{"issue":"12","key":"pgph.0004467.ref018","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1038\/jp.2016.150","article-title":"Prevalence and risk factors of chorioamnionitis in Dhaka, Bangladesh","volume":"36","author":"GJ Chan","year":"2016","journal-title":"J Perinatol"},{"issue":"9373","key":"pgph.0004467.ref019","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1016\/S0140-6736(03)13553-2","article-title":"Estimated early-onset group B streptococcal neonatal disease","volume":"361","author":"S Luck","year":"2003","journal-title":"Lancet"}],"container-title":["PLOS Global Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pgph.0004467","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T17:24:52Z","timestamp":1752513892000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pgph.0004467"}},"subtitle":[],"editor":[{"given":"Shiyam","family":"Sunder","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,7,14]]},"references-count":19,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2025,7,14]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pgph.0004467","relation":{},"ISSN":["2767-3375"],"issn-type":[{"value":"2767-3375","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,14]]}}}