{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T19:27:20Z","timestamp":1764617240565,"version":"3.46.0"},"reference-count":52,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Institut Pasteur de C\u00c3\u00b4te d'Ivoire"},{"DOI":"10.13039\/501100003762","name":"Institut Pasteur","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003762","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosglobalpublichealth.org"],"crossmark-restriction":false},"short-container-title":["PLOS Glob Public Health"],"abstract":"<jats:p>\n                    Cysticercosis is a parasitic disease caused by\n                    <jats:italic>Taenia solium<\/jats:italic>\n                    , primarily transmitted via fecal-oral route. It is a public health concern because it contributes to increasing morbidity of epilepsy. Its true prevalence remains largely unknown in C\u00f4te d\u2019Ivoire. This study aimed to estimate the seroprevalence of cysticercosis in rural southeastern C\u00f4te d\u2019Ivoire and identify risk factors. Two cross-sectional cluster sample surveys were conducted in villages in the departments of Dabou and Agboville. Data on socio-demographic, neurological history, knowledge about taeniasis\/cysticercosis complex and hygiene behaviors\u2019 were collected. A blood sample was collected for serological analysis to detect anti-cysticercosis immunoglobulin G antibodies by ELISA and EITB. The Stata survey command was used for statistical analysis. Qualitative variables were compared using the Chi2 test. A multivariate logistic regression was used to model cysticercosis seropositivity. Cysticercosis seroprevalence was estimated at 9.65% (95%CI: 4.83-18.34%) and 13.11% (95%CI: 9.55-17.74%) in Dabou and Agboville respectively. In Dabou, seropositivity was determined by area of residence and previous knowledge of cysticercosis. The rural population in the Toupah sub-prefecture was more likely to be seropositive (adjusted Odds Ratio [aOR]: 3.53, 95%CI: 1.09-11.44). In Agboville, older adults were 2.74 times more likely to be seropositive than youth at age under 16. Educated individuals (aOR: 0.63, 95%CI: 0.43-0.95), those of muslim faith (aOR: 0.56, 95%CI: 0.34-0.92) and those who reported washing raw vegetables before consumption (aOR: 0.45, 95%CI: 0.22-0.92) had a lower risk. This initial study confirms the circulation of\n                    <jats:italic>Taenia solium<\/jats:italic>\n                    and the endemicity of cysticercosis in these rural regions of south-eastern C\u00f4te d\u2019Ivoire, area that supply pigs to markets in Abidjan. Insufficient hygiene practices put communities at high risk of fecal-oral transmission. These findings showed public health issue of cysticercosis in rural areas of C\u00f4te d\u2019Ivoire, suggesting that targeted interventions should be considered to reduce transmission and associated neurological problems.\n                  <\/jats:p>","DOI":"10.1371\/journal.pgph.0004634","type":"journal-article","created":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T18:32:52Z","timestamp":1764613972000},"page":"e0004634","update-policy":"https:\/\/doi.org\/10.1371\/journal.pgph.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Human cysticercosis in Southeastern C\u00f4te d\u2019Ivoire: Seroprevalence and risk factors in two rural departments"],"prefix":"10.1371","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6482-3917","authenticated-orcid":true,"given":"Man-Koumba","family":"Soumahoro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kouadio Thierry-Borel","family":"N\u2019Dri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kouassi Eug\u00e8ne","family":"Koffi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariame Sarranh","family":"Fanny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gildas Boris","family":"Tazemda-Kuitsouc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yves Landry","family":"Kangah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kouadio Narcisse","family":"Tano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8620-0457","authenticated-orcid":true,"given":"Kouam\u00e9 Mathias","family":"N\u2019Dri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cataud Marius","family":"Gu\u00e9d\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Offianan Andr\u00e9","family":"Tour\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phane","family":"Petres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allico Joseph","family":"Djaman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mireille","family":"Nowakowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronan","family":"Jambou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2025,12,1]]},"reference":[{"issue":"15","key":"pgph.0004634.ref001","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1016\/S1286-4579(00)01336-8","article-title":"Taenia solium disease in humans and pigs: an ancient parasitosis disease rooted in developing countries and emerging as a major health problem of global dimensions","volume":"2","author":"E Sciutto","year":"2000","journal-title":"Microbes Infect"},{"key":"pgph.0004634.ref002","unstructured":"WHO. Taeniasis\/cysticercose. 2019 [cited 2019 Nov 24]. Available from: https:\/\/www.who.int\/fr\/news-room\/fact-sheets\/detail\/taeniasis-cysticercosis"},{"issue":"3","key":"pgph.0004634.ref003","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.antinf.2012.06.002","article-title":"Pr\u00e9vention et traitement de la cysticercose","volume":"14","author":"M Boussard","year":"2012","journal-title":"J Anti-Infectieux"},{"issue":"9383","key":"pgph.0004634.ref004","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0140-6736(03)14117-7","article-title":"Taenia solium cysticercosis","volume":"362","author":"Cysticercosis Working Group in Peru","year":"2003","journal-title":"Lancet"},{"key":"pgph.0004634.ref005","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/B978-012422150-5\/50034-2","article-title":"Cysticercosis and epilepsy","volume-title":"The epilepsies: etiologies and prevention","author":"AC Sakamoto","year":"1999"},{"issue":"8","key":"pgph.0004634.ref006","first-page":"588","article-title":"Neurocysticercosis in patients presenting with epilepsy at St Elizabeth\u2019s Hospital, Lusikisiki","volume":"99","author":"G Serrano Ocana","year":"2009","journal-title":"S Afr Med J"},{"issue":"1","key":"pgph.0004634.ref007","first-page":"25","article-title":"\u00c9pid\u00e9miologie de l\u2019\u00e9pilepsie en Afrique subsaharienne: une revue de la litt\u00e9rature","volume":"18","author":"EB Ngoungou","year":"2006","journal-title":"Epilepsies"},{"key":"pgph.0004634.ref008","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0014-4894(03)00111-5","article-title":"Taenia saginata: polymerase chain reaction for taeniasis diagnosis in human fecal samples","volume":"104","author":"CM Nunes","year":"2003","journal-title":"Exp Parasitol"},{"issue":"10","key":"pgph.0004634.ref009","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1111\/j.1365-3156.2005.01480.x","article-title":"Evaluation of Taenia solium and Taenia crassiceps cysticercal antigens for the serodiagnosis of neurocysticercosis","volume":"10","author":"GC Arruda","year":"2005","journal-title":"Trop Med Int Health"},{"issue":"6","key":"pgph.0004634.ref010","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1128\/CDLI.8.6.1140-1144.2001","article-title":"Serodiagnosis of human cysticercosis by using antigens from vesicular fluid of Taenia crassiceps cysticerci","volume":"8","author":"EC Bueno","year":"2001","journal-title":"Clin Diagn Lab Immunol"},{"issue":"1","key":"pgph.0004634.ref011","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1179\/136485906X78445","article-title":"Evaluation of ELISA and dot blots for the serodiagnosis of neurocysticercosis, in children found to have single or multiple enhancing lesions in computerized tomographic scans of the brain","volume":"100","author":"J Mandal","year":"2006","journal-title":"Ann Trop Med Parasitol"},{"issue":"3","key":"pgph.0004634.ref012","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.pt.2009.12.008","article-title":"Immunodiagnosis of Taenia solium taeniosis\/cysticercosis","volume":"26","author":"N Deckers","year":"2010","journal-title":"Trends Parasitol"},{"issue":"5","key":"pgph.0004634.ref013","doi-asserted-by":"crossref","first-page":"610","DOI":"10.4269\/ajtmh.1992.46.610","article-title":"Immunodiagnosis of human cysticercosis (Taenia solium): a field comparison of an antibody-enzyme-linked immunosorbent assay (ELISA), an antigen-ELISA, and an enzyme-linked immunoelectrotransfer blot (EITB) assay in Peru. 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