{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T18:08:01Z","timestamp":1788890881252,"version":"build-2803163510"},"reference-count":43,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["INV-0003212"],"award-info":[{"award-number":["INV-0003212"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosglobalpublichealth.org"],"crossmark-restriction":false},"short-container-title":["PLOS Glob Public Health"],"abstract":"<jats:p>Community case management has been scaled up nationally in Zambia over the last decade. However, there is limited evidence on how this nationwide implementation has affected febrile patients\u2019 access to malaria diagnosis and treatment in Zambia. This study analyzed four rounds of Malaria Indicator Survey (MIS) data (2012\u20132021) to evaluate: 1) proportion of all-ages individuals with fever who sought treatment from a formal provider, 2) proportion of individuals going to CHWs over time, among those who sought treatment at a formal provider, 3) time duration between fever onset and treatment seeking at a formal provider, and 4) proportion of children &lt;5 with malaria that received Artemether-Lumefantrine (AL) treatment. Mixed-effect logit models were employed to examine determinants of treatment-seeking behavior and factors affecting AL receipt among children &lt;5 with malaria cases. The proportion of febrile patients seeking treatment remained below 60% throughout 2012\u20132021, and AL receipt among children with malaria cases consistently stayed below 50%. The mean interval between fever onset and initial treatment-seeking encounter decreased from 2.42 days in 2012 to 1.71 days in 2021. Among formal care seekers, CHW utilization increased from 1.5% in 2012 to 10.0% in 2018 before declining to 3.2% in 2021. Longer walking time to the nearest health facility was associated with lower odds of treatment seeking, whereas CHW density was not associated with treatment seeking or AL receipt. Children who did not go to formal providers had lower odds of AL receipt than those who sought treatment from CHWs. Despite nationwide CCM scale-up over the last decade, significant barriers persist in malaria patients\u2019 access to diagnosis and treatment in Zambia. Our results indicate that while CCM coverage should be maintained and further expanded, additional complementary interventions are also needed to overcome remaining access barriers.<\/jats:p>","DOI":"10.1371\/journal.pgph.0007216","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T17:30:25Z","timestamp":1788888625000},"page":"e0007216","update-policy":"https:\/\/doi.org\/10.1371\/journal.pgph.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Access to malaria diagnosis and treatment in Zambia in the context of scaling-up community case management: Results from repeated national cross-sectional surveys"],"prefix":"10.1371","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3999-0705","authenticated-orcid":true,"given":"Zhiyuan","family":"Mao","sequence":"first","affiliation":[{"name":"Tulane University","place":["New Orleans, Louisiana, United States of America"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Bennett","sequence":"additional","affiliation":[{"name":"PATH","place":["Seattle, Washington, United States of America"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kafula","family":"Silumbe","sequence":"additional","affiliation":[{"name":"PATH","place":["Lusaka, Zambia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Miller","sequence":"additional","affiliation":[{"name":"PATH","place":["Lusaka, Zambia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Millar","sequence":"additional","affiliation":[{"name":"PATH","place":["Seattle, Washington, United States of America"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4291-7899","authenticated-orcid":true,"given":"Hannah","family":"Slater","sequence":"additional","affiliation":[{"name":"PATH","place":["Seattle, Washington, United States of America"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josh","family":"Yukich","sequence":"additional","affiliation":[{"name":"Tulane University","place":["New Orleans, Louisiana, United States of America"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7248-7730","authenticated-orcid":true,"given":"Ruth A.","family":"Ashton","sequence":"additional","affiliation":[{"name":"Tulane University","place":["New Orleans, Louisiana, United States of America"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Kyomuhangi","sequence":"additional","affiliation":[{"name":"Tulane University","place":["New Orleans, Louisiana, United States of America"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8639-3914","authenticated-orcid":true,"given":"Andrew","family":"Andrada","sequence":"additional","affiliation":[{"name":"Tulane University","place":["New Orleans, Louisiana, United States of America"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-7383-1159","authenticated-orcid":true,"given":"Refilwe","family":"Karabo","sequence":"additional","affiliation":[{"name":"Tulane University","place":["New Orleans, Louisiana, United States of America"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2205-622X","authenticated-orcid":true,"given":"Thomas P.","family":"Eisele","sequence":"additional","affiliation":[{"name":"Tulane University","place":["New Orleans, Louisiana, United States of America"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,9,8]]},"reference":[{"key":"pgph.0007216.ref001","unstructured":"World malaria report 2022. 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