{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T02:40:21Z","timestamp":1791772821052,"version":"4.3.4"},"reference-count":44,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2006,9,12]],"date-time":"2006-09-12T00:00:00Z","timestamp":1158019200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosmedicine.org"],"crossmark-restriction":false},"short-container-title":["PLoS Med"],"DOI":"10.1371\/journal.pmed.0030348","type":"journal-article","created":{"date-parts":[[2006,9,11]],"date-time":"2006-09-11T13:55:01Z","timestamp":1157982901000},"page":"e348","update-policy":"https:\/\/doi.org\/10.1371\/journal.pmed.corrections_policy","source":"Crossref","is-referenced-by-count":107,"title":["A New Arthritis Therapy with Oxidative Burst Inducers"],"prefix":"10.1371","volume":"3","author":[{"given":"Malin","family":"Hultqvist","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Olofsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyra A","family":"Gelderman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Holmberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rikard","family":"Holmdahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2006,9,12]]},"reference":[{"key":"journal-pmed-0030348-b001","first-page":"226","volume":"15","author":"Shanahan","year":"2003","journal-title":"Curr Opin Rheumatol","ISSN":"https:\/\/id.crossref.org\/issn\/1040-8711","issn-type":"print"},{"key":"journal-pmed-0030348-b002","first-page":"113","volume":"75","author":"Davies","year":"1997","journal-title":"Immunol Cell Biol","ISSN":"https:\/\/id.crossref.org\/issn\/0818-9641","issn-type":"print"},{"key":"journal-pmed-0030348-b003","first-page":"802","volume":"2","author":"Wanstrat","year":"2001","journal-title":"Nat Immunol","ISSN":"https:\/\/id.crossref.org\/issn\/1529-2908","issn-type":"print"},{"key":"journal-pmed-0030348-b004","first-page":"163","volume":"26","author":"Horikawa","year":"2000","journal-title":"Nat Genet","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"key":"journal-pmed-0030348-b005","first-page":"845","volume":"70","author":"Lesage","year":"2002","journal-title":"Am J Hum Genet","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"key":"journal-pmed-0030348-b006","first-page":"666","volume":"32","author":"Prokunina","year":"2002","journal-title":"Nat Genet","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"key":"journal-pmed-0030348-b007","first-page":"25","volume":"33","author":"Olofsson","year":"2003","journal-title":"Nat Genet","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"key":"journal-pmed-0030348-b008","first-page":"1464","volume":"93","author":"Babior","year":"1999","journal-title":"Blood","ISSN":"https:\/\/id.crossref.org\/issn\/0006-4971","issn-type":"print"},{"key":"journal-pmed-0030348-b009","first-page":"1025","volume":"78","author":"Sheppard","year":"2005","journal-title":"J Leukoc Biol","ISSN":"https:\/\/id.crossref.org\/issn\/0741-5400","issn-type":"print"},{"key":"journal-pmed-0030348-b010","first-page":"200","volume":"9","author":"Rosen","year":"1995","journal-title":"FASEB J","ISSN":"https:\/\/id.crossref.org\/issn\/0892-6638","issn-type":"print"},{"key":"journal-pmed-0030348-b011","first-page":"747","volume":"11","author":"Henrotin","year":"2003","journal-title":"Osteoarthr Cartil","ISSN":"https:\/\/id.crossref.org\/issn\/1063-4584","issn-type":"print"},{"key":"journal-pmed-0030348-b012","first-page":"652","volume":"82","author":"Olofsson","year":"2003","journal-title":"Genomics","ISSN":"https:\/\/id.crossref.org\/issn\/0888-7543","issn-type":"print"},{"key":"journal-pmed-0030348-b013","first-page":"216","volume":"68","author":"Hua","year":"2000","journal-title":"J Leukoc Biol","ISSN":"https:\/\/id.crossref.org\/issn\/0741-5400","issn-type":"print"},{"key":"journal-pmed-0030348-b014","first-page":"3","volume":"232","author":"Dahlgren","year":"1999","journal-title":"J Immunol Methods","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1759","issn-type":"print"},{"key":"journal-pmed-0030348-b015","first-page":"181","volume":"166","author":"Smith","year":"1975","journal-title":"Arch Biochem Biophys","ISSN":"https:\/\/id.crossref.org\/issn\/0003-9861","issn-type":"print"},{"key":"journal-pmed-0030348-b016","author":"Holmdahl","year":"1998","journal-title":"Human Genome Methods"},{"key":"journal-pmed-0030348-b017","first-page":"89","volume":"178","author":"Vowells","year":"1995","journal-title":"J Immunol Methods","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1759","issn-type":"print"},{"key":"journal-pmed-0030348-b018","first-page":"302","volume":"52","author":"Buege","year":"1978","journal-title":"Methods Enzymol","ISSN":"https:\/\/id.crossref.org\/issn\/0076-6879","issn-type":"print"},{"key":"journal-pmed-0030348-b019","first-page":"583","volume":"31","author":"Saxne","year":"1992","journal-title":"Br J Rheumatol","ISSN":"https:\/\/id.crossref.org\/issn\/1460-2172","issn-type":"print"},{"key":"journal-pmed-0030348-b020","first-page":"1675","volume":"149","author":"Vingsbo","year":"1996","journal-title":"Am J Pathol","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9440","issn-type":"print"},{"key":"journal-pmed-0030348-b021","first-page":"273","volume":"26","author":"El Benna","year":"2002","journal-title":"Inflammation","ISSN":"https:\/\/id.crossref.org\/issn\/0360-3997","issn-type":"print"},{"key":"journal-pmed-0030348-b022","first-page":"1172","volume":"176","author":"Holmberg","year":"2006","journal-title":"J Immunol","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"key":"journal-pmed-0030348-b023","first-page":"857","volume":"146","author":"Trentham","year":"1977","journal-title":"J Exp Med","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1007","issn-type":"print"},{"key":"journal-pmed-0030348-b024","first-page":"1237","volume":"26","author":"Stuart","year":"1983","journal-title":"Arthritis Rheum","ISSN":"https:\/\/id.crossref.org\/issn\/0004-3591","issn-type":"print"},{"key":"journal-pmed-0030348-b025","first-page":"401","volume":"20","author":"Vingsbo-Lundberg","year":"1998","journal-title":"Nat Genet","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"key":"journal-pmed-0030348-b026","first-page":"359","volume":"99","author":"Vingsbo","year":"1995","journal-title":"Clin Exp Immunol","ISSN":"https:\/\/id.crossref.org\/issn\/0009-9104","issn-type":"print"},{"key":"journal-pmed-0030348-b027","first-page":"975","volume":"36","author":"Drabikova","year":"2002","journal-title":"Free Radic Res","ISSN":"https:\/\/id.crossref.org\/issn\/1071-5762","issn-type":"print"},{"key":"journal-pmed-0030348-b028","first-page":"244","volume":"2","author":"Brennan","year":"1989","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"key":"journal-pmed-0030348-b029","first-page":"151","volume":"38","author":"Arend","year":"1995","journal-title":"Arthritis Rheum","ISSN":"https:\/\/id.crossref.org\/issn\/0004-3591","issn-type":"print"},{"key":"journal-pmed-0030348-b030","first-page":"907","volume":"344","author":"Choy","year":"2001","journal-title":"N Engl J Med","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"key":"journal-pmed-0030348-b031","first-page":"32","volume":"115","author":"\u00c5kerlund","year":"1999","journal-title":"Clin Exp Immunol","ISSN":"https:\/\/id.crossref.org\/issn\/0009-9104","issn-type":"print"},{"key":"journal-pmed-0030348-b032","first-page":"12646","volume":"101","author":"Hultqvist","year":"2004","journal-title":"Proc Natl Acad Sci U S A","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"key":"journal-pmed-0030348-b033","first-page":"751","volume":"182","author":"Jackson","year":"1995","journal-title":"J Exp Med","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1007","issn-type":"print"},{"key":"journal-pmed-0030348-b034","first-page":"4756","volume":"61","author":"Schmielau","year":"2001","journal-title":"Cancer Res","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"key":"journal-pmed-0030348-b035","first-page":"183","volume":"153","author":"van der Veen","year":"2004","journal-title":"J Neuroimmunol","ISSN":"https:\/\/id.crossref.org\/issn\/0165-5728","issn-type":"print"},{"key":"journal-pmed-0030348-b036","first-page":"735","volume":"10","author":"Hildeman","year":"1999","journal-title":"Immunity","ISSN":"https:\/\/id.crossref.org\/issn\/1074-7613","issn-type":"print"},{"key":"journal-pmed-0030348-b037","first-page":"400","volume":"22","author":"Gringhuis","year":"2002","journal-title":"Mol Cell Biol","ISSN":"https:\/\/id.crossref.org\/issn\/0270-7306","issn-type":"print"},{"key":"journal-pmed-0030348-b038","first-page":"1491","volume":"99","author":"Angelini","year":"2002","journal-title":"Proc Natl Acad Sci U S A","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"key":"journal-pmed-0030348-b039","first-page":"818","volume":"5","author":"Jackson","year":"2004","journal-title":"Nat Immunol","ISSN":"https:\/\/id.crossref.org\/issn\/1529-2908","issn-type":"print"},{"key":"journal-pmed-0030348-b040","first-page":"387","volume":"9","author":"Meng","year":"2002","journal-title":"Mol Cell","ISSN":"https:\/\/id.crossref.org\/issn\/1097-2765","issn-type":"print"},{"key":"journal-pmed-0030348-b041","first-page":"330","volume":"75","author":"Begovich","year":"2004","journal-title":"Am J Hum Genet","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"key":"journal-pmed-0030348-b042","first-page":"920","volume":"173","author":"Remans","year":"2004","journal-title":"J Immunol","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"key":"journal-pmed-0030348-b043","first-page":"501","volume":"175","author":"Bluml","year":"2005","journal-title":"J Immunol","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"key":"journal-pmed-0030348-b044","first-page":"1197","volume":"23","author":"Walton","year":"2003","journal-title":"Arterioscler Thromb Vasc Biol","ISSN":"https:\/\/id.crossref.org\/issn\/1079-5642","issn-type":"print"}],"container-title":["PLoS Medicine"],"original-title":[],"language":"en","deposited":{"date-parts":[[2018,10,19]],"date-time":"2018-10-19T20:59:13Z","timestamp":1539982753000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pmed.0030348"}},"subtitle":[],"editor":[{"given":"Cor","family":"Verweij","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2006,9,12]]},"references-count":44,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2006,9,12]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pmed.0030348","relation":{},"ISSN":["1549-1676"],"issn-type":[{"value":"1549-1676","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,9,12]]}}}