{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T21:56:05Z","timestamp":1792706165451,"version":"4.5.0"},"reference-count":17,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2016,3,29]],"date-time":"2016-03-29T00:00:00Z","timestamp":1459209600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosmedicine.org"],"crossmark-restriction":false},"short-container-title":["PLoS Med"],"DOI":"10.1371\/journal.pmed.1001980","type":"journal-article","created":{"date-parts":[[2016,3,29]],"date-time":"2016-03-29T18:14:24Z","timestamp":1459275264000},"page":"e1001980","update-policy":"https:\/\/doi.org\/10.1371\/journal.pmed.corrections_policy","source":"Crossref","is-referenced-by-count":82,"title":["Performance of the GeneXpert Ebola Assay for Diagnosis of Ebola Virus Disease in Sierra Leone: A Field Evaluation Study"],"prefix":"10.1371","volume":"13","author":[{"given":"Amanda E.","family":"Semper","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Jana","family":"Broadhurst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jade","family":"Richards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geraldine M.","family":"Foster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J. H.","family":"Simpson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher H.","family":"Logue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Daniel","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim J. G.","family":"Brooks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Murray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nira R.","family":"Pollock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2016,3,29]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1056\/NEJMoa0907847","article-title":"Rapid molecular detection of tuberculosis and rifampin resistance","volume":"363","author":"CC Boehme","year":"2010","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"e0142216","DOI":"10.1371\/journal.pone.0142216","article-title":"Analytical performance characteristics of the Cepheid GeneXpert Ebola assay for the detection of Ebola virus","volume":"10","author":"BA Pinsky","year":"2015","journal-title":"PLoS ONE"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"954","DOI":"10.4269\/ajtmh.2010.09-0636","article-title":"Comprehensive panel of real-time TaqMan polymerase chain reaction assays for detection and absolute quantification of filoviruses, arenaviruses, and New World hantaviruses","volume":"82","author":"AR Trombley","year":"2010","journal-title":"Am J Trop Med Hyg"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/S0140-6736(15)61042-X","article-title":"ReEBOV Antigen Rapid Test kit for point-of-care and laboratory-based testing for Ebola virus disease: a field validation study","volume":"386","author":"MJ Broadhurst","year":"2015","journal-title":"Lancet"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1191\/096228099673819272","article-title":"Measuring agreement in method comparison studies","volume":"8","author":"JM Bland","year":"1999","journal-title":"Stat Methods Med Res"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"2956","DOI":"10.1128\/JCM.01317-15","article-title":"Comparison of FilmArray(R) and qRT-PCR for the detection of Zaire Ebolavirus from contrived and clinical specimens","volume":"53","author":"TR Southern","year":"2015","journal-title":"J Clin Microbiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1056\/NEJMoa1411680","article-title":"Clinical illness and outcomes in patients with Ebola in Sierra Leone","volume":"371","author":"JS Schieffelin","year":"2014","journal-title":"N Engl J Med"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1093\/cid\/civ397","article-title":"Field evaluation of capillary blood samples as a collection specimen for the rapid diagnosis of Ebola virus infection during an outbreak emergency","volume":"61","author":"T Strecker","year":"2015","journal-title":"Clin Infect Dis"},{"issue":"12","key":"ref9","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES2015.20.12.21073","article-title":"Evaluation of a point-of-care blood test for identification of Ebola virus disease at Ebola holding units, Western Area, Sierra Leone, January to February 2015","volume":"20","author":"NF Walker","year":"2015","journal-title":"Euro Surveill"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"e0003734","DOI":"10.1371\/journal.pntd.0003734","article-title":"The case for improved diagnostic tools to control Ebola virus disease in West Africa and how to get there","volume":"9","author":"AC Chua","year":"2015","journal-title":"PLoS Negl Trop Dis"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1038\/516154a","article-title":"Ebola experts seek to expand testing","volume":"516","author":"D Butler","year":"2014","journal-title":"Nature"},{"key":"ref12","unstructured":"World Health Organization. Target product profile for Zaire ebolavirus rapid, simple test to be used in the control of the Ebola outbreak in West Africa. 2014 Oct 3 [cited 10 Mar 2015]. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.finddiagnostics.org\/programs\/ebola\/product_development\/tpp.html\" xlink:type=\"simple\">http:\/\/www.finddiagnostics.org\/programs\/ebola\/product_development\/tpp.html<\/ext-link>."},{"key":"ref13","unstructured":"US Food and Drug Administration. Emergency use authorization. [cited 23 Nov 2015]. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.fda.gov\/EmergencyPreparedness\/Counterterrorism\/MedicalCountermeasures\/MCMLegalRegulatoryandPolicyFramework\/ucm182568.htm\" xlink:type=\"simple\">http:\/\/www.fda.gov\/EmergencyPreparedness\/Counterterrorism\/MedicalCountermeasures\/MCMLegalRegulatoryandPolicyFramework\/ucm182568.htm<\/ext-link>."},{"key":"ref14","unstructured":"World Health Organization. Emergency use assessment and listing (EUAL) procedure for Ebola virus disease (IVDs). [cited 23 Nov 2015]. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.who.int\/diagnostics_laboratory\/procurement\/purchasing\/en\/\" xlink:type=\"simple\">http:\/\/www.who.int\/diagnostics_laboratory\/procurement\/purchasing\/en\/<\/ext-link>."},{"key":"ref15","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1016\/S0140-6736(15)01109-5","article-title":"ReEBOV Antigen Rapid Test kit for Ebola\u2014authors\u2019 reply","volume":"386","author":"MJ Broadhurst","year":"2015","journal-title":"Lancet"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1128\/JCM.00527-15","article-title":"Use of the FilmArray System for detection of Zaire ebolavirus in a small hospital in Bo, Sierra Leone","volume":"53","author":"TA Leski","year":"2015","journal-title":"J Clin Microbiol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1128\/JCM.02287-15","article-title":"Evaluation of the Biofire FilmArray BioThreat-E Test (v2.5) for rapid identification of ebola virus disease in heat-treated blood samples obtained in Sierra Leone and the United Kingdom","volume":"54","author":"SA Weller","year":"2016","journal-title":"J. Clin Microbiol"}],"container-title":["PLOS Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pmed.1001980","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T20:10:06Z","timestamp":1540325406000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pmed.1001980"}},"subtitle":[],"editor":[{"given":"Lorenz","family":"von Seidlein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,3,29]]},"references-count":17,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2016,3,29]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pmed.1001980","relation":{},"ISSN":["1549-1676"],"issn-type":[{"value":"1549-1676","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,29]]}}}