{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T01:34:10Z","timestamp":1790472850337,"version":"4.1.0"},"reference-count":47,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2017,6,15]],"date-time":"2017-06-15T00:00:00Z","timestamp":1497484800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"UNAIDS Regional Office for West and Central Africa"},{"name":"NIH, through the HPTN Modelling Centre","award":["NIH UM1 AI068617"],"award-info":[{"award-number":["NIH UM1 AI068617"]}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosmedicine.org"],"crossmark-restriction":false},"short-container-title":["PLoS Med"],"DOI":"10.1371\/journal.pmed.1002321","type":"journal-article","created":{"date-parts":[[2017,6,15]],"date-time":"2017-06-15T16:39:40Z","timestamp":1497544780000},"page":"e1002321","update-policy":"https:\/\/doi.org\/10.1371\/journal.pmed.corrections_policy","source":"Crossref","is-referenced-by-count":47,"title":["Population-level impact of an accelerated HIV response plan to reach the UNAIDS 90-90-90 target in C\u00f4te d\u2019Ivoire: Insights from mathematical modeling"],"prefix":"10.1371","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8363-4388","authenticated-orcid":true,"given":"Mathieu","family":"Maheu-Giroux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1103-9587","authenticated-orcid":true,"given":"Juan F.","family":"Vesga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Souleymane","family":"Diabat\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Alary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5482-2419","authenticated-orcid":true,"given":"Stefan","family":"Baral","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daouda","family":"Diouf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kouam\u00e9","family":"Abo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Claude","family":"Boily","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,6,15]]},"reference":[{"issue":"8","key":"ref1","doi-asserted-by":"crossref","first-page":"e361","DOI":"10.1016\/S2352-3018(16)30087-X","article-title":"Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980\u20132015: the Global Burden of Disease Study 2015","volume":"3","year":"2016","journal-title":"The Lancet HIV"},{"key":"ref2","first-page":"300-","article-title":"Modeling the HIV Epidemic in Cote d'Ivoire: Impact of Past Interventions","volume":"32","author":"M Maheu-Giroux","year":"2016","journal-title":"Aids Res Hum Retrovir"},{"key":"ref3","unstructured":"Diabat\u00e9 S, Maheu-Giroux M, Vesga J, Boily M, Alary M. Plan d'acc\u00e9l\u00e9ration de la r\u00e9ponse nationale au VIH en C\u00f4te d'Ivoire: Rapport pr\u00e9sent\u00e9 \u00e0 ONUSIDA\u2014R\u00e9gion d'Afrique de l'ouest et du centre; 2015. 139 p."},{"key":"ref4","unstructured":"UNAIDS. 90-90-90: an ambitious treatment target to help end the AIDS epidemic. Geneva, Switzerland: Joint United Nations Programme on HIV\/AIDS (UNAIDS), 2014 Contract No.: JC2684."},{"key":"ref5","unstructured":"UNAIDS. Fast-Track: ending the AIDS epidemic by 2030. Geneva, Switzerland: Joint United Nations Programme on HIV\/AIDS (UNAIDS), 2014 Contract No.: JC2686."},{"issue":"5","key":"ref6","doi-asserted-by":"crossref","first-page":"e221","DOI":"10.1016\/S2352-3018(16)00037-0","article-title":"Botswana's progress toward achieving the 2020 UNAIDS 90-90-90 antiretroviral therapy and virological suppression goals: a population-based survey","volume":"3","author":"T Gaolathe","year":"2016","journal-title":"Lancet HIV"},{"issue":"Suppl 1","key":"ref7","doi-asserted-by":"crossref","first-page":"S61","DOI":"10.1097\/QAD.0000000000000109","article-title":"Exploring the population-level impact of antiretroviral treatment: the influence of baseline intervention context","volume":"28","author":"S Mishra","year":"2014","journal-title":"AIDS"},{"key":"ref8","article-title":"Enqu\u00eate D\u00e9mographique et de Sant\u00e9 et \u00e0 Indicateurs Multiples de C\u00f4te d'Ivoire 2011\u20132012","year":"2012"},{"issue":"Suppl 2","key":"ref9","doi-asserted-by":"crossref","first-page":"S91","DOI":"10.1097\/QAI.0000000000000448","article-title":"An urgent need for integration of family planning services into HIV care: the high burden of unplanned pregnancy, termination of pregnancy, and limited contraception use among female sex workers in C\u00f4te d'Ivoire","volume":"68","author":"S Schwartz","year":"2015","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"4","key":"ref10","doi-asserted-by":"crossref","first-page":"e0125218","DOI":"10.1371\/journal.pone.0125218","article-title":"The Epidemiology of HIV and Prevention Needs of Men Who Have Sex with Men in Abidjan, Cote d'Ivoire","volume":"10","author":"AJ Hakim","year":"2015","journal-title":"PLoS ONE"},{"key":"ref11","article-title":"Plan strat\u00e9gique national de lutte contre l'infection a VIH, le SIDA et les IST 2011\u20132015","year":"2011"},{"key":"ref12","article-title":"Changing dynamics of HIV transmission in C\u00f4te d\u2019Ivoire: modeling who acquired and transmitted infections and estimating the impact of past HIV interventions (1976\u20132015)","author":"M Maheu-Giroux","year":"2017","journal-title":"JAIDS"},{"key":"ref13","article-title":"Enqu\u00eate D\u00e9mographique et de Sant\u00e9, C\u00f4te d'Ivoire 1998\u20131999","year":"2001"},{"key":"ref14","article-title":"Enqu\u00eate sur les Indicateurs du Sida, C\u00f4te d'Ivoire 2005","year":"2006"},{"key":"ref15","article-title":"Enqu\u00eate D\u00e9mographique et de Sant\u00e9, C\u00f4te d'Ivoire 1994","author":"S N'Cho","year":"1995"},{"issue":"8","key":"ref16","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1093\/infdis\/jis480","article-title":"Quantifying ongoing HIV-1 exposure in HIV-1-serodiscordant couples to identify individuals with potential host resistance to HIV-1","volume":"206","author":"RD Mackelprang","year":"2012","journal-title":"J Infect Dis"},{"issue":"7","key":"ref17","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1007\/s10461-015-1002-5","article-title":"Risk Factors for HIV Acquisition in High Risk Women in a Generalised Epidemic Setting","volume":"19","author":"N Naicker","year":"2015","journal-title":"AIDS Behav"},{"key":"ref18","article-title":"World Population Prospects:The 2015 Revision\u2014Key Findings and Advance Tables","year":"2015"},{"issue":"Suppl 1","key":"ref19","doi-asserted-by":"crossref","first-page":"i11","DOI":"10.1136\/sti.2008.029991","article-title":"Bayesian melding for estimating uncertainty in national HIV prevalence estimates","volume":"84","author":"L Alkema","year":"2008","journal-title":"Sex Transm Infect"},{"issue":"452","key":"ref20","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1080\/01621459.2000.10474324","article-title":"Inference for Deterministic Simulation Models: The Bayesian Melding Approach","volume":"95","author":"D Poole","year":"2000","journal-title":"Journal of the American Statistical Association"},{"issue":"4","key":"ref21","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1111\/j.1541-0420.2010.01399.x","article-title":"Estimating and projecting trends in HIV\/AIDS generalized epidemics using Incremental Mixture Importance Sampling","volume":"66","author":"AE Raftery","year":"2010","journal-title":"Biometrics"},{"issue":"12","key":"ref22","first-page":"1193","article-title":"Seroprevalence of HIV infection in the general population of the C\u00f4te d'Ivoire, West Africa","volume":"3","author":"SN Benoit","year":"1990","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"3","key":"ref23","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/BF02098100","article-title":"Rapid spread of HIV infections in Abidjan, Ivory Coast, 1987\u20131990","volume":"11","author":"K Koffi","year":"1992","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"2","key":"ref24","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1097\/00002030-200201250-00015","article-title":"Increase in condom use and decline in HIV and sexually transmitted diseases among female sex workers in Abidjan, C\u00f4te d'Ivoire, 1991\u20131998","volume":"16","author":"PD Ghys","year":"2002","journal-title":"AIDS"},{"issue":"3","key":"ref25","doi-asserted-by":"crossref","first-page":"e32627","DOI":"10.1371\/journal.pone.0032627","article-title":"HIV and STI prevalence among female sex workers in C\u00f4te d'Ivoire: why targeted prevention programs should be continued and strengthened","volume":"7","author":"B Vuylsteke","year":"2012","journal-title":"PLoS ONE"},{"key":"ref26","unstructured":"Bamba A, Grover E, Ezouatchi R, Thiam-Niangoin M, Papworth E, Grosso A, et al. \u00c9tude biologique et comportementale des IST\/VIH\/SIDA chez les professionnelles du sexe du district d'Abidjan et examen des interventions en direction des populations clefs en C\u00f4te d'Ivoire. Minist\u00e8re de la Sant\u00e9 et de la Lutte contre le SIDA, ENDA Sant\u00e9, Johns Hopkins University, 2014."},{"issue":"11","key":"ref27","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1097\/00002030-200307250-00014","article-title":"HIV prevalence and risk behavior among clients of female sex workers in Abidjan, C\u00f4te d'Ivoire","volume":"17","author":"BL Vuylsteke","year":"2003","journal-title":"AIDS"},{"key":"ref28","unstructured":"DIPE. Rapport annuel VIH\/Sida du secteur sant\u00e9 en C\u00f4te d'Ivoire 2007\u20132008. Abidjan, C\u00f4te d'Ivoire: Direction de l'Information, de la Planification et de l'\u00c9valuation. Minist\u00e8re de la Sant\u00e9 et de l'Hygi\u00e8ne Publique, 2009."},{"key":"ref29","unstructured":"DIPE. Rapport annuel des indicateurs VIH du secteur sant\u00e9 en C\u00f4te d'Ivoire 2009. Abidjan, C\u00f4te d'Ivoire: Direction de l'Information, de la Planification et de l'\u00c9valuation. Minist\u00e8re de la Sant\u00e9 et de l'Hygi\u00e8ne Publique., 2010."},{"key":"ref30","unstructured":"DIPE. Rapport annuel des indicateurs VIH du secteur Sant\u00e9 en C\u00f4te d'Ivoire 2010. Abidjan, C\u00f4te d'Ivoire: Direction de l'Information, de la Planification et de l'\u00c9valuation. Minist\u00e8re de la Sant\u00e9 et de l'Hygi\u00e8ne Publique., 2011."},{"key":"ref31","unstructured":"DIPE. Rapport annuel des indicateurs VIH du secteur sant\u00e9 en C\u00f4te d'Ivoire 2011. Abidjan, C\u00f4te d'Ivoire: Direction de l'Information, de la Planification, et de l'\u00c9valuation. Minist\u00e8re de la Sant\u00e9 et de la Lutte contre le Sida, 2012."},{"key":"ref32","unstructured":"DIPE. Rapport annuel des indicateurs VIH du secteur sant\u00e9 en C\u00f4te d'Ivoire 2012. Abidjan, C\u00f4te d'Ivoire: Direction de l'Information, de la Planification et de l'\u00c9valuation. Minist\u00e8re de la Sant\u00e9 et de la Lutte contre le SIDA., 2013."},{"key":"ref33","unstructured":"DIPE. Rapport annuel des indicateurs VIH du secteur sant\u00e9 en C\u00f4te d'Ivoire 2013. Abidjan, C\u00f4te d'Ivoire: Direction de l'Information, de la Planification et de l'\u00c9valuation, 2014."},{"key":"ref34","unstructured":"DIPE. Rapport annuel des indicateurs VIH du secteur sant\u00e9 en C\u00f4te d'Ivoire 2014\u2014Non consolid\u00e9. Abidjan, C\u00f4te d'Ivoire: Direction de l'Information, de la Planification et de l'\u00c9valuation. Minist\u00e8re de la sant\u00e9 et de la lutte contre le sida., 2015."},{"issue":"6","key":"ref35","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1056\/NEJMoa1105243","article-title":"Prevention of HIV-1 infection with early antiretroviral therapy","volume":"365","author":"MS Cohen","year":"2011","journal-title":"N Engl J Med"},{"issue":"9731","key":"ref36","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1016\/S0140-6736(10)60705-2","article-title":"Heterosexual HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort analysis","volume":"375","author":"D Donnell","year":"2010","journal-title":"Lancet"},{"issue":"9989","key":"ref37","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0140-6736(15)60658-4","article-title":"Defeating AIDS\u2014advancing global health","volume":"386","author":"P Piot","year":"2015","journal-title":"Lancet"},{"issue":"11","key":"ref38","doi-asserted-by":"crossref","first-page":"e1001907","DOI":"10.1371\/journal.pmed.1001907","article-title":"The HIV Treatment Gap: Estimates of the Financial Resources Needed versus Available for Scale-Up of Antiretroviral Therapy in 97 Countries from 2015 to 2020","volume":"12","author":"A Dutta","year":"2015","journal-title":"PLoS Med"},{"issue":"2","key":"ref39","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/COH.0000000000000034","article-title":"Concentrated HIV subepidemics in generalized epidemic settings","volume":"9","author":"F Tanser","year":"2014","journal-title":"Curr Opin HIV AIDS"},{"issue":"9939","key":"ref40","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0140-6736(14)61053-9","article-title":"Maximising the effect of combination HIV prevention through prioritisation of the people and places in greatest need: a modelling study","volume":"384","author":"SJ Anderson","year":"2014","journal-title":"Lancet"},{"issue":"2","key":"ref41","doi-asserted-by":"crossref","first-page":"e1002240","DOI":"10.1371\/journal.pmed.1002240","article-title":"Evidence for scaling up HIV treatment in sub-Saharan Africa: A call for incorporating health system constraints","volume":"14","author":"E Mikkelsen","year":"2017","journal-title":"PLoS Med"},{"issue":"5","key":"ref42","doi-asserted-by":"crossref","first-page":"e1002015","DOI":"10.1371\/journal.pmed.1002015","article-title":"Initiating Antiretroviral Therapy for HIV at a Patient's First Clinic Visit: The RapIT Randomized Controlled Trial","volume":"13","author":"S Rosen","year":"2016","journal-title":"PLoS Med"},{"issue":"7","key":"ref43","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1097\/QAD.0000000000001435","article-title":"Determinants of time from HIV infection to linkage-to-care in rural KwaZulu-Natal, South Africa","volume":"31","author":"M Maheu-Giroux","year":"2017","journal-title":"AIDS"},{"key":"ref44","article-title":"Validity of data on self-reported HIV status in Malawi and Uganda and implications for measurement of ARV coverage","author":"J Fishel","year":"2014"},{"key":"ref45","unstructured":"UNAIDS. Global AIDS Response Progress Reporting 2016\u2014Construction of core indicators for monitoring the 2011 United Nations Political Declaration on HIV and AIDS. Geneva, Switzerland: Joint United Nations Programme on HIV\/AIDS, 2016."},{"issue":"46","key":"ref46","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.15585\/mmwr.mm6446a3","article-title":"Scale-up of HIV Viral Load Monitoring\u2014Seven Sub-Saharan African Countries","volume":"64","author":"S Lecher","year":"2015","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"7580","key":"ref47","doi-asserted-by":"crossref","first-page":"S68","DOI":"10.1038\/nature16046","article-title":"Sustainable HIV treatment in Africa through viral-load-informed differentiated care","volume":"528","author":"A Phillips","year":"2015","journal-title":"Nature"}],"container-title":["PLOS Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pmed.1002321","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,22]],"date-time":"2018-10-22T13:28:50Z","timestamp":1540214930000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pmed.1002321"}},"subtitle":[],"editor":[{"given":"Nicola","family":"Low","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,6,15]]},"references-count":47,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2017,6,15]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pmed.1002321","relation":{},"ISSN":["1549-1676"],"issn-type":[{"value":"1549-1676","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,15]]}}}