{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T18:46:58Z","timestamp":1768589218713,"version":"3.49.0"},"reference-count":58,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T00:00:00Z","timestamp":1602720000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201100005C"],"award-info":[{"award-number":["HHSN268201100005C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201100006C"],"award-info":[{"award-number":["HHSN268201100006C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201100007C"],"award-info":[{"award-number":["HHSN268201100007C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201100008C"],"award-info":[{"award-number":["HHSN268201100008C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201100009C"],"award-info":[{"award-number":["HHSN268201100009C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201100010C"],"award-info":[{"award-number":["HHSN268201100010C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201100011C"],"award-info":[{"award-number":["HHSN268201100011C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268 201100012C"],"award-info":[{"award-number":["HHSN268 201100012C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01HL59367"],"award-info":[{"award-number":["R01HL59367"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01HL135008"],"award-info":[{"award-number":["R01HL135008"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01HL143224"],"award-info":[{"award-number":["R01HL143224"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"crossref","award":["R01HL150342"],"award-info":[{"award-number":["R01HL150342"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"crossref","award":["R01HL148218"],"award-info":[{"award-number":["R01HL148218"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["K24HL152008"],"award-info":[{"award-number":["K24HL152008"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Brigham and Women\u2019s Heart and Vascular Center","award":["Watkins Discovery Award"],"award-info":[{"award-number":["Watkins Discovery Award"]}]}],"content-domain":{"domain":["www.plosmedicine.org"],"crossmark-restriction":false},"short-container-title":["PLoS Med"],"DOI":"10.1371\/journal.pmed.1003361","type":"journal-article","created":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T17:28:00Z","timestamp":1602782880000},"page":"e1003361","update-policy":"https:\/\/doi.org\/10.1371\/journal.pmed.corrections_policy","source":"Crossref","is-referenced-by-count":13,"title":["Pulmonary vascular dysfunction among people aged over 65 years in the community in the Atherosclerosis Risk In Communities (ARIC) Study: A cross-sectional analysis"],"prefix":"10.1371","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4217-9497","authenticated-orcid":true,"given":"Kanako","family":"Teramoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rio","family":"Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Claggett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7174-9858","authenticated-orcid":true,"given":"Jenine E.","family":"John","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott D.","family":"Solomon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dalane","family":"Kitzman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2635-2699","authenticated-orcid":true,"given":"Aaron R.","family":"Folsom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7871-6143","authenticated-orcid":true,"given":"Mary","family":"Cushman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7179-718X","authenticated-orcid":true,"given":"Kunihiro","family":"Matsushita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5629-4138","authenticated-orcid":true,"given":"Hicham","family":"Skali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1056-4451","authenticated-orcid":true,"given":"Amil M.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2020,10,15]]},"reference":[{"issue":"13","key":"pmed.1003361.ref001","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1161\/CIRCULATIONAHA.115.020207","article-title":"Association of Borderline Pulmonary Hypertension With Mortality and Hospitalization in a Large Patient Cohort: Insights From the Veterans Affairs Clinical Assessment, Reporting, and Tracking Program","volume":"133","author":"BA Maron","year":"2016","journal-title":"Circulation"},{"issue":"1","key":"pmed.1003361.ref002","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/eurheartj\/ehv317","article-title":"2015 ESC\/ERS guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (APEC), International Society for Heart and Lung Transplantation (ISHLT)","volume":"37","author":"N Gali\u00e8","year":"2016","journal-title":"Eur Heart J"},{"issue":"6","key":"pmed.1003361.ref003","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s11906-013-0396-6","article-title":"Physiology of the pulmonary circulation and the right heart","volume":"15","author":"R Naeije","year":"2013","journal-title":"Curr Hypertens Rep"},{"issue":"17","key":"pmed.1003361.ref004","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1161\/CIRCULATIONAHA.117.031608","article-title":"Global Pulmonary Vascular Remodeling in Pulmonary Hypertension Associated With Heart Failure and Preserved or Reduced Ejection Fraction","volume":"137","author":"AU Fayyaz","year":"2017","journal-title":"Circulation"},{"issue":"5","key":"pmed.1003361.ref005","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1378\/chest.13-1510","article-title":"Prognostic relevance of pulmonary arterial compliance in patients with chronic heart failure","volume":"145","author":"P Pellegrini","year":"2014","journal-title":"Chest"},{"issue":"3","key":"pmed.1003361.ref006","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1136\/thx.33.3.335","article-title":"Structural basis for the changing physical properties of human pulmonary vessels with age","volume":"33","author":"EH Mackay","year":"1978","journal-title":"Thorax"},{"issue":"20","key":"pmed.1003361.ref007","doi-asserted-by":"crossref","first-page":"2663","DOI":"10.1161\/CIRCULATIONAHA.108.838698","article-title":"Age-associated increases in pulmonary artery systolic pressure in the general population","volume":"119","author":"CS Lam","year":"2009","journal-title":"Circulation"},{"issue":"5","key":"pmed.1003361.ref008","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1161\/CIRCULATIONAHA.116.024825","article-title":"Contemporary Assessment of Left Ventricular Diastolic Function in Older Adults: The atherosclerosis risk in communities study","volume":"135","author":"AM Shah","year":"2017","journal-title":"Circulation"},{"issue":"2","key":"pmed.1003361.ref009","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/s11906-014-0523-z","article-title":"The conundrum of arterial stiffness, elevated blood pressure, and aging","volume":"17","author":"M AlGhatrif","year":"2015","journal-title":"Curr Hypertens Rep"},{"issue":"4","key":"pmed.1003361.ref010","doi-asserted-by":"crossref","first-page":"4058","DOI":"10.1016\/j.ijcard.2013.07.005","article-title":"Accuracy and precision of echocardiography versus right heart catheterization for the assessment of pulmonary hypertension","volume":"168","author":"M D'Alto","year":"2013","journal-title":"Int J Cardiol"},{"key":"pmed.1003361.ref011","doi-asserted-by":"crossref","first-page":"e005711","DOI":"10.1161\/CIRCIMAGING.116.005711","article-title":"Accuracy of Echocardiography to Estimate Pulmonary Artery Pressures With Exercise: A Simultaneous Invasive-Noninvasive Comparison","volume":"10","author":"AC van Riel","year":"2017","journal-title":"Circ Cardiovasc Imaging"},{"issue":"4","key":"pmed.1003361.ref012","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1093\/oxfordjournals.aje.a115184","article-title":"The atherosclerosis risk in communities (aric) study: Design and objectives. The ARIC investigators","volume":"129","year":"1989","journal-title":"Am J Epidemiol"},{"issue":"7","key":"pmed.1003361.ref013","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/j.amjcard.2007.11.061","article-title":"Heart failure incidence and survival (from the atherosclerosis risk in communities study).","volume":"101","author":"LR Loehr","year":"2008","journal-title":"Am J Cardiol"},{"issue":"2","key":"pmed.1003361.ref014","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1161\/CIRCHEARTFAILURE.111.963199","article-title":"Classification of heart failure in the Atherosclerosis Risk in Communities (ARIC) study: A comparison of diagnostic criteria","volume":"5","author":"WD Rosamond","year":"2012","journal-title":"Circ Heart Fail"},{"issue":"1","key":"pmed.1003361.ref015","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1161\/CIRCIMAGING.113.000736","article-title":"Rationale and design of a multicenter echocardiographic study to assess the relationship between cardiac structure and function and heart failure risk in a biracial cohort of community-dwelling elderly persons: The Atherosclerosis Risk in Communities study","volume":"7","author":"AM Shah","year":"2014","journal-title":"Circ Cardiovasc Imaging"},{"issue":"3","key":"pmed.1003361.ref016","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1093\/ehjci\/jev014","article-title":"Recommendations for cardiac chamber quantification by echocardiography in adults: An update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"16","author":"RM Lang","year":"2015","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"12","key":"pmed.1003361.ref017","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1093\/ehjci\/jew082","article-title":"Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"17","author":"SF Nagueh","year":"2016","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"4","key":"pmed.1003361.ref018","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1161\/01.CIR.70.4.657","article-title":"Noninvasive estimation of right ventricular systolic pressure by doppler ultrasound in patients with tricuspid regurgitation","volume":"70","author":"PG Yock","year":"1984","journal-title":"Circulation"},{"issue":"4","key":"pmed.1003361.ref019","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/S0735-1097(85)80477-0","article-title":"Continuous wave Doppler determination of right ventricular pressure: A simultaneous Doppler-catheterization study in 127 patients","volume":"6","author":"PJ Currie","year":"1985","journal-title":"J Am Coll Cardiol"},{"issue":"7","key":"pmed.1003361.ref020","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.echo.2009.04.007","article-title":"An alternative echocardiographic method to estimate mean pulmonary artery pressure: Diagnostic and clinical implications","volume":"22","author":"JF Aduen","year":"2009","journal-title":"J Am Soc Echocardiogr"},{"issue":"6","key":"pmed.1003361.ref021","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/S0735-1097(02)02973-X","article-title":"A Simple Method for Noninvasive Estimation of Pulmonary Vascular Resistance","volume":"41","author":"AE Abbas","year":"2003","journal-title":"J Am Coll Cardiol"},{"issue":"13","key":"pmed.1003361.ref022","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1093\/eurheartj\/ehn103","article-title":"Pulmonary vascular resistance and compliance stay inversely related during treatment of pulmonary hypertension","volume":"29","author":"JW Lankhaar","year":"2008","journal-title":"Eur Heart J"},{"key":"pmed.1003361.ref023","first-page":"141","volume-title":"Respiratory Medicine","author":"JJ Marini","year":"1997","edition":"2"},{"key":"pmed.1003361.ref024","first-page":"18","volume-title":"Manual of Pulmonary Function Testing","author":"G Ruppel","year":"1991","edition":"5"},{"issue":"4","key":"pmed.1003361.ref025","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1164\/rccm.201204-0596PP","article-title":"Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary","volume":"187","author":"J Vestbo","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"pmed.1003361.ref026","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.amjmed.2004.01.018","article-title":"Deep vein thrombosis and pulmonary embolism in two cohorts: the longitudinal investigation of thromboembolism etiology","volume":"117","author":"M Cushman","year":"2004","journal-title":"Am J Med"},{"issue":"9","key":"pmed.1003361.ref027","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"A new equation to estimate glomerular filtration rate","volume":"150","author":"AS Levey","year":"2009","journal-title":"Ann Intern Med"},{"issue":"2","key":"pmed.1003361.ref028","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0895-4356(95)00041-0","article-title":"Community surveillance of coronary heart disease in the atherosclerosis risk in communities (aric) study: Methods and initial two years' experience","volume":"49","author":"AD White","year":"1996","journal-title":"J Clin Epidemiol"},{"issue":"1","key":"pmed.1003361.ref029","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.ahj.2009.05.010","article-title":"Incidence of atrial fibrillation in whites and African-Americans: the Atherosclerosis Risk in Communities (aric) study","volume":"158","author":"A Alonso","year":"2009","journal-title":"Am Heart J"},{"issue":"7","key":"pmed.1003361.ref030","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.echo.2010.05.010","article-title":"Guidelines for the echocardiographic assessment of the right heart in adults: A report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography","volume":"23","author":"LG Rudski","year":"2010","journal-title":"J Am Soc Echocardiogr"},{"issue":"13","key":"pmed.1003361.ref031","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1161\/CIRCULATIONAHA.110.005264","article-title":"Cardiac troponin T measured by a highly sensitive assay predicts coronary heart disease, heart failure, and mortality in the Atherosclerosis Risk in Communities study","volume":"123","author":"JT Saunders","year":"2011","journal-title":"Circulation"},{"issue":"25 Suppl","key":"pmed.1003361.ref032","doi-asserted-by":"crossref","first-page":"D109","DOI":"10.1016\/j.jacc.2013.10.036","article-title":"Pulmonary hypertension in chronic lung diseases","volume":"62","author":"W Seeger","year":"2013","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"pmed.1003361.ref033","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2105\/AJPH.88.1.15","article-title":"Use and misuse of population attributable fractions","volume":"88","author":"B Rockhill","year":"1998","journal-title":"Am J Public Health"},{"issue":"1","key":"pmed.1003361.ref034","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1097\/EDE.0b013e318230e861","article-title":"Accounting for bias due to selective attrition: The example of smoking and cognitive decline","volume":"23","author":"J Weuve","year":"2012","journal-title":"Epidemiology"},{"issue":"8","key":"pmed.1003361.ref035","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1093\/aje\/kwu020","article-title":"Impact of differential attrition on the association of education with cognitive change over 20 years of follow-up: The ARIC neurocognitive study","volume":"179","author":"RF Gottesman","year":"2014","journal-title":"Am J Epidemiol"},{"issue":"4","key":"pmed.1003361.ref036","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1001\/jamacardio.2018.0128","article-title":"Association Between Hemodynamic Markers of Pulmonary Hypertension and Outcomes in Heart Failure With Preserved Ejection Fraction","volume":"3","author":"RR Vanderpool","year":"2018","journal-title":"JAMA Cardiol"},{"issue":"13","key":"pmed.1003361.ref037","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.jacc.2008.11.051","article-title":"Pulmonary hypertension in heart failure with preserved ejection fraction: a community-based study","volume":"53","author":"CS Lam","year":"2009","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"pmed.1003361.ref038","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1378\/chest.12-3079","article-title":"Echocardiography of the pulmonary circulation and right ventricular function: exploring the physiologic spectrum in 1,480 normal subjects","volume":"145","author":"A D'Andrea","year":"2014","journal-title":"Chest"},{"issue":"3","key":"pmed.1003361.ref039","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.echo.2011.11.022","article-title":"Pulmonary artery pressure in young healthy subjects","volume":"25","author":"A Grossman","year":"2012","journal-title":"J Am Soc Echocardiogr"},{"issue":"23","key":"pmed.1003361.ref040","doi-asserted-by":"crossref","first-page":"2797","DOI":"10.1161\/hc4801.100076","article-title":"Clinical correlates and reference intervals for pulmonary artery systolic pressure among echocardiographically normal subjects","volume":"104","author":"BM McQuillan","year":"2001","journal-title":"Circulation"},{"issue":"134","key":"pmed.1003361.ref041","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1183\/09059180.00007814","article-title":"The changing landscape of pulmonary arterial hypertension and implications for patient care","volume":"23","author":"MM Hoeper","year":"2014","journal-title":"Eur Respir Rev"},{"issue":"25","key":"pmed.1003361.ref042","doi-asserted-by":"crossref","first-page":"2310","DOI":"10.1161\/CIRCULATIONAHA.113.008461","article-title":"Right ventricular function in heart failure with preserved ejection fraction: A community-based study","volume":"130","author":"SF Mohammed","year":"2014","journal-title":"Circulation"},{"issue":"2","key":"pmed.1003361.ref043","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1161\/CIRCULATIONAHA.111.051540","article-title":"Pulmonary capillary wedge pressure augments right ventricular pulsatile loading","volume":"125","author":"RJ Tedford","year":"2012","journal-title":"Circulation"},{"issue":"2","key":"pmed.1003361.ref044","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1097\/MAT.0000000000000467","article-title":"Pulmonary arterial compliance improves rapidly after left ventricular assist device implantation","volume":"63","author":"SC Masri","year":"2017","journal-title":"ASAIO J"},{"issue":"6","key":"pmed.1003361.ref045","doi-asserted-by":"crossref","first-page":"H2154","DOI":"10.1152\/ajpheart.00694.2009","article-title":"RC time constant of single lung equals that of both lungs together: A study in chronic thromboembolic pulmonary hypertension","volume":"297","author":"N Saouti","year":"2009","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"17","key":"pmed.1003361.ref046","doi-asserted-by":"crossref","first-page":"4279","DOI":"10.1113\/jphysiol.2012.234310","article-title":"Pulmonary vascular distensibility predicts aerobic capacity in healthy individuals","volume":"590","author":"S Lalande","year":"2012","journal-title":"J Physiol"},{"issue":"4","key":"pmed.1003361.ref047","doi-asserted-by":"crossref","first-page":"H1731","DOI":"10.1152\/ajpheart.00336.2006","article-title":"Quantification of right ventricular afterload in patients with and without pulmonary hypertension","volume":"291","author":"JW Lankhaar","year":"2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"6","key":"pmed.1003361.ref048","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1111\/j.1365-2796.2003.01211.x","article-title":"Obstructive and restrictive lung disease and functional limitation: Data from the third national health and nutrition examination","volume":"254","author":"DM Mannino","year":"2003","journal-title":"J Intern Med"},{"issue":"1","key":"pmed.1003361.ref049","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1161\/CIRCULATIONAHA.110.979203","article-title":"Cardiac dysfunction and noncardiac dysfunction as precursors of heart failure with reduced and preserved ejection fraction in the community","volume":"124","author":"CS Lam","year":"2011","journal-title":"Circulation"},{"issue":"2","key":"pmed.1003361.ref050","doi-asserted-by":"crossref","first-page":"1601792","DOI":"10.1183\/13993003.01792-2016","article-title":"Incidence of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: a contemporary view of the published literature","volume":"49","author":"YM Ende-Verhaar","year":"2017","journal-title":"Eur Respir J"},{"issue":"4","key":"pmed.1003361.ref051","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1161\/CIRCHEARTFAILURE.114.001366","article-title":"Elevated pulmonary artery systolic pressure predicts heart failure admissions in African Americans: Jackson Heart Study","volume":"7","author":"G Choudhary","year":"2014","journal-title":"Circ Heart Fail"},{"issue":"14","key":"pmed.1003361.ref052","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1161\/01.CIR.0000013771.30198.82","article-title":"Pulmonary hypertension and risk of death in cardiomyopathy: Patients with myocarditis are at higher risk","volume":"105","author":"TP Cappola","year":"2002","journal-title":"Circulation"},{"issue":"1","key":"pmed.1003361.ref053","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/ejhf.192","article-title":"Pulmonary arterial capacitance in patients with heart failure and reactive pulmonary hypertension","volume":"17","author":"R Dragu","year":"2015","journal-title":"Eur J Heart Fail"},{"issue":"3","key":"pmed.1003361.ref054","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.hfc.2014.04.008","article-title":"Phenotypic spectrum of heart failure with preserved ejection fraction","volume":"10","author":"SJ Shah","year":"2014","journal-title":"Heart Fail Clin"},{"issue":"3","key":"pmed.1003361.ref055","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1161\/CIRCULATIONAHA.114.010637","article-title":"Phenomapping for novel classification of heart failure with preserved ejection fraction","volume":"131","author":"SJ Shah","year":"2015","journal-title":"Circulation"},{"issue":"8","key":"pmed.1003361.ref056","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.jchf.2018.06.008","article-title":"Heart Failure With Preserved Ejection Fraction Expert Panel Report: Current Controversies and Implications for Clinical Trials","volume":"6","author":"KS Parikh","year":"2018","journal-title":"JACC Heart Fail"},{"issue":"7","key":"pmed.1003361.ref057","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1164\/rccm.200811-1691OC","article-title":"Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension","volume":"179","author":"MR Fisher","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"pmed.1003361.ref058","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1183\/09031936.05.00035205","article-title":"Interpretative strategies for lung function tests","volume":"26","author":"R Pellegrino","year":"2005","journal-title":"Eur Respir J"}],"container-title":["PLOS Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pmed.1003361","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T17:29:01Z","timestamp":1602782941000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pmed.1003361"}},"subtitle":[],"editor":[{"given":"Kazem","family":"Rahimi","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,10,15]]},"references-count":58,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2020,10,15]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pmed.1003361","relation":{},"ISSN":["1549-1676"],"issn-type":[{"value":"1549-1676","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,15]]}}}