{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T04:42:23Z","timestamp":1792816943762,"version":"4.5.0"},"reference-count":26,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2008,4,9]],"date-time":"2008-04-09T00:00:00Z","timestamp":1207699200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0000219","type":"journal-article","created":{"date-parts":[[2008,4,8]],"date-time":"2008-04-08T17:52:05Z","timestamp":1207677125000},"page":"e219","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":49,"title":["Tissue Invasion by Entamoeba histolytica: Evidence of Genetic Selection and\/or DNA Reorganization Events in Organ Tropism"],"prefix":"10.1371","volume":"2","author":[{"given":"Ibne Karim M.","family":"Ali","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahram","family":"Solaymani-Mohammadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmine","family":"Akhter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shantanu","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Gorrini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Calderaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah K.","family":"Parker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashidul","family":"Haque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William A.","family":"Petri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Graham","family":"Clark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2008,4,9]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/S0169-4758(00)01730-0","article-title":"Estimating the impact of amebiasis on health.","volume":"16","author":"WA Petri Jr","year":"2000","journal-title":"Parasitol Today"},{"key":"ref2","first-page":"13","article-title":"WHO\/PAHO\/UNESCO report. A consultation with experts on amoebiasis. Mexico City, Mexico 28\u201329 January, 1997.","volume":"18","author":"Anonymous","year":"1997","journal-title":"Epidemiol Bull"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"475","DOI":"10.4269\/ajtmh.2006.74.475","article-title":"Cognitive effects of diarrhea, malnutrition, and <italic>Entamoeba histolytica<\/italic> infection on school age children in Dhaka, Bangladesh.","volume":"74","author":"JL Tarleton","year":"2006","journal-title":"Am J Trop Med Hyg"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1016\/j.trstmh.2005.12.012","article-title":"<italic>Entamoeba histolytica<\/italic>-associated diarrheal illness is negatively associated with the growth of preschool children: evidence from a prospective study.","volume":"100","author":"D Mondal","year":"2006","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1086\/381272","article-title":"Influence of human leukocyte antigen class II alleles on susceptibility to <italic>Entamoeba histolytica<\/italic> infection in Bangladeshi children.","volume":"189","author":"P Duggal","year":"2004","journal-title":"J Infect Dis"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1128\/JCM.01335-06","article-title":"Evidence for a link between parasite genotype and outcome of infection with <italic>Entamoeba histolytica<\/italic>.","volume":"45","author":"IK Ali","year":"2007","journal-title":"J Clin Microbiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"5842","DOI":"10.1128\/JCM.43.12.5842-5847.2005","article-title":"Use of PCR amplification of tRNA gene-linked short tandem repeats for genotyping <italic>Entamoeba histolytica<\/italic>.","volume":"43","author":"IK Ali","year":"2005","journal-title":"J Clin Microbiol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1006\/expr.2001.4652","article-title":"<italic>Entamoeba histolytica<\/italic>: genetic diversity of clinical isolates from Bangladesh as demonstrated by polymorphisms in the serine-rich gene.","volume":"99","author":"PF Ayeh-Kumi","year":"2001","journal-title":"Exp Parasitol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"3235","DOI":"10.1128\/JCM.38.9.3235-3239.2000","article-title":"Diagnosis of amebic liver abscess and intestinal infection with the TechLab <italic>Entamoeba histolytica<\/italic> II antigen detection and antibody tests.","volume":"38","author":"R Haque","year":"2000","journal-title":"J Clin Microbiol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.trstmh.2005.07.015","article-title":"<italic>Entamoeba histolytica<\/italic> and Entamoeba dispar: comparison of two PCR assays for diagnosis in a non-endemic setting.","volume":"100","author":"A Calderaro","year":"2006","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"10881","DOI":"10.1093\/nar\/16.22.10881","article-title":"Multiple sequence alignment with hierarchical clustering.","volume":"16","author":"F Corpet","year":"1988","journal-title":"Nucleic Acids Res"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.molbiopara.2005.10.013","article-title":"Unique organisation of tRNA genes in <italic>Entamoeba histolytica<\/italic>.","volume":"146","author":"CG Clark","year":"2006","journal-title":"Mol Biochem Parasitol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1093\/molbev\/msm238","article-title":"Patterns of evolution in the unique tRNA gene arrays of the genus <italic>Entamoeba<\/italic>.","volume":"25","author":"B Tawari","year":"2008","journal-title":"Mol Biol Evol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.exppara.2004.07.005","article-title":"<italic>Leishmania (Viannia)<\/italic>: genetic analysis of cutaneous and mucosal strains isolated from the same patient.","volume":"108","author":"P Cuervo","year":"2004","journal-title":"Exp Parasitol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"4081","DOI":"10.1128\/JCM.40.11.4081-4090.2002","article-title":"Remarkable genetic polymorphism among <italic>Entamoeba histolytica<\/italic> isolates from a limited geographic area.","volume":"40","author":"A Haghighi","year":"2002","journal-title":"J Clin Microbiol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"3748","DOI":"10.1128\/JCM.41.8.3748-3756.2003","article-title":"Geographic diversity among genotypes of <italic>Entamoeba histolytica<\/italic> field isolates.","volume":"41","author":"A Haghighi","year":"2003","journal-title":"J Clin Microbiol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/0166-6851(93)90006-J","article-title":"A family of transcripts (K2) of <italic>Entamoeba histolytica<\/italic> contains polymorphic repetitive regions with highly conserved elements.","volume":"59","author":"S Kohler","year":"1993","journal-title":"Mol Biochem Parasitol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"4976","DOI":"10.1073\/pnas.87.13.4976","article-title":"Cloning and expression of a membrane antigen of <italic>Entamoeba histolytica<\/italic> possessing multiple tandem repeats.","volume":"87","author":"SL Stanley Jr","year":"1990","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"578","DOI":"10.4269\/ajtmh.2002.66.578","article-title":"Epidemiology of amebiasis in a region of high incidence of amebic liver abscess in central Vietnam.","volume":"66","author":"J Blessmann","year":"2002","journal-title":"Am J Trop Med Hyg"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.arcmed.2005.09.010","article-title":"Diversity of clinical isolates of <italic>Entamoeba histolytica<\/italic> in Japan.","volume":"37","author":"T Nozaki","year":"2006","journal-title":"Arch Med Res"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1126\/science.1086132","article-title":"Structural dynamics of eukaryotic chromosome evolution.","volume":"301","author":"EE Eichler","year":"2003","journal-title":"Science"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1089\/dna.2006.25.359","article-title":"Increased recombination between active tRNA genes.","volume":"25","author":"MJ Pratt-Hyatt","year":"2006","journal-title":"DNA Cell Biol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1097\/00005792-198207000-00003","article-title":"New concepts of amebic liver abscess derived from hepatic imaging, serodiagnosis, and hepatic enzymes in 67 consecutive cases in San Diego.","volume":"61","author":"D Katzenstein","year":"1982","journal-title":"Medicine (Baltimore)"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1093\/clinids\/14.4.889","article-title":"Asymptomatic intestinal colonization by pathogenic <italic>Entamoeba histolytica<\/italic> in amebic liver abscess: prevalence, response to therapy, and pathogenic potential.","volume":"14","author":"EM Irusen","year":"1992","journal-title":"Clin Infect Dis"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/1471-2180-7-41","article-title":"Detection of excretory <italic>Entamoeba histolytica<\/italic> DNA in the urine, and detection of <italic>E. histolytica<\/italic> DNA and lectin antigen in the liver abscess pus for the diagnosis of amoebic liver abscess.","volume":"7","author":"SC Parija","year":"2007","journal-title":"BMC Microbiol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.4049\/jimmunol.177.2.1208","article-title":"Resistance of C57BL\/6 mice to amoebiasis is mediated by nonhemopoietic cells but requires hemopoietic IL-10 production.","volume":"177","author":"S Hamano","year":"2006","journal-title":"J Immunol"}],"updated-by":[{"DOI":"10.1371\/annotation\/6fb9dd82-4678-48cb-a3b4-9856fdbe58e5","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2008,6,2]],"date-time":"2008-06-02T00:00:00Z","timestamp":1212364800000}}],"container-title":["PLoS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0000219","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,3]],"date-time":"2020-05-03T20:35:02Z","timestamp":1588538102000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0000219"}},"subtitle":[],"editor":[{"given":"Anuradha","family":"Lohia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2008,4,9]]},"references-count":26,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2008,4,9]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0000219","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1103904.561047","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.1103904.589934","asserted-by":"object"}]},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,4,9]]}}}