{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T21:02:55Z","timestamp":1768770175945,"version":"3.49.0"},"reference-count":33,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2009,6,9]],"date-time":"2009-06-09T00:00:00Z","timestamp":1244505600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0000457","type":"journal-article","created":{"date-parts":[[2009,6,8]],"date-time":"2009-06-08T22:36:08Z","timestamp":1244500568000},"page":"e457","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":86,"title":["Evaluation of Wuchereria bancrofti GST as a Vaccine Candidate for Lymphatic Filariasis"],"prefix":"10.1371","volume":"3","author":[{"given":"Anandharaman","family":"Veerapathran","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gajalakshmi","family":"Dakshinamoorthy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Munirathinam","family":"Gnanasekar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryada Venkata Rami","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramaswamy","family":"Kalyanasundaram","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2009,6,9]]},"reference":[{"key":"ref1","first-page":"1","article-title":"Lymphatic filariasis: the disease and its control. Fifth report of the WHO Expert Committee on Filariasis.","volume":"821","year":"1992","journal-title":"World Health Organ Tech Rep Ser"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1017\/S0031182000066646","article-title":"Re-assessing the global prevalence and distribution of lymphatic filariasis.","volume":"112 (Pt 4)","author":"E Michael","year":"1996","journal-title":"Parasitology"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1080\/00034983.1992.11812684","article-title":"Diethylcarbamazine treatment of bancroftian and malayan filariasis with emphasis on side effects.","volume":"86","author":"PC Fan","year":"1992","journal-title":"Ann Trop Med Parasitol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1172\/JCI113850","article-title":"Protective immunity in bancroftian filariasis. Selective recognition of a 43-kD larval stage antigen by infection-free individuals in an endemic area.","volume":"83","author":"DO Freedman","year":"1989","journal-title":"J Clin Invest"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1111\/j.1365-3024.1985.tb00107.x","article-title":"Serum dependent cell-mediated immune reactions to <italic>Brugia pahangi<\/italic> infective larvae.","volume":"7","author":"R Chandrashekar","year":"1985","journal-title":"Parasite Immunol"},{"key":"ref6","first-page":"319","article-title":"Immunogenicity of homogenates of the developmental stages of <italic>Litomosoides carinii<\/italic> in albino rats.","volume":"38","author":"K Mehta","year":"1981","journal-title":"Acta Trop"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/0020-7519(90)90005-8","article-title":"Antibody-mediated cytotoxic effects in vitro and in vivo of rat cells on infective larvae of <italic>Brugia malayi<\/italic>.","volume":"20","author":"R Chandrashekar","year":"1990","journal-title":"Int J Parasitol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/0014-4894(86)90043-3","article-title":"<italic>Brugia malayi<\/italic>: rat cell interactions with infective larvae mediated by complement.","volume":"62","author":"R Chandrashekar","year":"1986","journal-title":"Exp Parasitol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"33","DOI":"10.18388\/abp.2006_3361","article-title":"Molecules released by helminth parasites involved in hostcolonization.","volume":"53","author":"JM Dzik","year":"2006","journal-title":"Acta Biochim Pol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1016\/S0264-410X(96)00147-8","article-title":"Protection of cattle against <italic>Fasciola hepatica<\/italic> infection by vaccination with glutathione S-transferase.","volume":"14","author":"CA Morrison","year":"1996","journal-title":"Vaccine"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1002\/eji.1830230223","article-title":"Protective immunity induced in rat schistosomiasis by a single dose of the Sm28GST recombinant antigen: effector mechanisms involving IgE and IgA antibodies.","volume":"23","author":"D Grezel","year":"1993","journal-title":"Eur J Immunol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"3905","DOI":"10.4049\/jimmunol.145.11.3905","article-title":"Glutathione S-transferase. Novel vaccine against <italic>Fasciola hepatica<\/italic> infection in sheep.","volume":"145","author":"JL Sexton","year":"1990","journal-title":"J Immunol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.exppara.2004.12.003","article-title":"<italic>Setaria cervi<\/italic>: immunoprophylactic potential of glutathione-S-transferase against filarial parasite <italic>Brugia malayi<\/italic>.","volume":"109","author":"S Gupta","year":"2005","journal-title":"Exp Parasitol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1159\/000053656","article-title":"Vaccine strategies against schistosomiasis: from concepts to clinical trials.","volume":"124","author":"A Capron","year":"2001","journal-title":"Int Arch Allergy Immunol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1111\/j.1365-3024.1993.tb00623.x","article-title":"Suppression of <italic>Schistosoma bovis<\/italic> egg production in cattle by vaccination with either glutathione S-transferase or keyhole limpet haemocyanin.","volume":"15","author":"HO Bushara","year":"1993","journal-title":"Parasite Immunol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1111\/j.1365-3024.1994.tb00367.x","article-title":"Vaccination of goats against the trematode <italic>Schistosoma bovis<\/italic> with a recombinant homologous schistosome-derived glutathione S-transferase.","volume":"16","author":"D Boulanger","year":"1994","journal-title":"Parasite Immunol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"527","DOI":"10.4049\/jimmunol.150.2.527","article-title":"IgA antibodies to a protective antigen in human <italic>Schistosomiasis mansoni<\/italic>.","volume":"150","author":"JM Grzych","year":"1993","journal-title":"J Immunol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.exppara.2008.01.014","article-title":"<italic>Fasciola gigantica<\/italic> and <italic>Schistosoma mansoni<\/italic>: vaccine potential of recombinant glutathione S-transferase (rFgGST26) against infections in mice.","volume":"119","author":"N Preyavichyapugdee","year":"2008","journal-title":"Exp Parasitol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1007\/s00894-005-0234-0","article-title":"Structure of glutathione S-transferase of the filarial parasite <italic>Wuchereria bancrofti<\/italic>: a target for drug development against adult worm.","volume":"11","author":"ST Nathan","year":"2005","journal-title":"J Mol Model"},{"key":"ref20","first-page":"7130","article-title":"Glutathione S-transferases. The first enzymatic step in mercapturic acid formation.","volume":"249","author":"WH Habig","year":"1974","journal-title":"J Biol Chem"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1128\/IAI.66.3.1142-1148.1998","article-title":"Relationship of impairment of schistosome 28-kilodalton glutathione S-transferase (GST) activity to expression of immunity to <italic>Schistosoma mattheei<\/italic> in calves vaccinated with recombinant <italic>Schistosoma bovis<\/italic> 28-kilodalton GST.","volume":"66","author":"JM Grzych","year":"1998","journal-title":"Infect Immun"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1046\/j.1365-3024.2000.00300.x","article-title":"Juvenile <italic>Fasciola hepatica<\/italic> are resistant to killing <italic>in vitro<\/italic> by free radicals compared with larvae of <italic>Schistosoma mansoni<\/italic>.","volume":"22","author":"D Piedrafita","year":"2000","journal-title":"Parasite Immunol"},{"key":"ref23","first-page":"15","article-title":"<italic>Brugia malayi<\/italic>: serum dependent cell-mediated reactions to microfilariae.","volume":"16","author":"R Chandrashekar","year":"1985","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s004360050507","article-title":"<italic>Trichinella spiralis<\/italic>: in vitro cytotoxicity of peritoneal cells against synchronous newborn larvae of different age.","volume":"85","author":"B Moskwa","year":"1999","journal-title":"Parasitol Res"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"4707","DOI":"10.1128\/IAI.72.8.4707-4715.2004","article-title":"Novel phage display-based subtractive screening to identify vaccine candidates of <italic>Brugia malayi<\/italic>.","volume":"72","author":"M Gnanasekar","year":"2004","journal-title":"Infect Immun"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1017\/S0031182000061369","article-title":"Glutathione transferase in helminths.","volume":"100 (Pt 2)","author":"PM Brophy","year":"1990","journal-title":"Parasitology"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0166-6851(93)90071-5","article-title":"Biochemical properties of cloned glutathione S-transferases from <italic>Schistosoma mansoni<\/italic> and <italic>Schistosoma japonicum<\/italic>.","volume":"61","author":"J Walker","year":"1993","journal-title":"Mol Biochem Parasitol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0166-6851(94)00205-2","article-title":"Biochemical analysis of recombinant glutathione S-transferase of <italic>Fasciola hepatica<\/italic>.","volume":"69","author":"L Salvatore","year":"1995","journal-title":"Mol Biochem Parasitol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"4094","DOI":"10.1016\/j.vaccine.2008.03.099","article-title":"Filarial glutathione-S-transferase: a potential vaccine candidate against lymphatic filariasis.","volume":"26","author":"S Rathaur","year":"2008","journal-title":"Vaccine"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1046\/j.1365-3156.1997.d01-384.x","article-title":"Characterization of human immune responses to the cytosolic superoxide dismutase and glutathione S-transferase from <italic>Onchocerca volvulus<\/italic>.","volume":"2","author":"NW Brattig","year":"1997","journal-title":"Trop Med Int Health"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"4174","DOI":"10.1128\/IAI.68.7.4174-4179.2000","article-title":"The abundant larval transcript-1 and -2 genes of <italic>Brugia malayi<\/italic> encode stage-specific candidate vaccine antigens for filariasis.","volume":"68","author":"WF Gregory","year":"2000","journal-title":"Infect Immun"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/j.1365-3024.1996.tb01031.x","article-title":"Glutathione-binding proteins of <italic>Setaria digitata<\/italic>: antibody responses in human infected with <italic>Wuchereria bancrofti<\/italic>.","volume":"18","author":"M Bal","year":"1996","journal-title":"Parasite Immunol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"4201","DOI":"10.4049\/jimmunol.143.12.4201","article-title":"Protective immunity against <italic>Brugia malayi<\/italic> infective larvae in mice. II. Induction by a T cell-dependent antigen isolated by monoclonal antibody affinity chromatography and SDS-PAGE.","volume":"143","author":"B Hammerberg","year":"1989","journal-title":"J Immunol"}],"container-title":["PLoS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0000457","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T16:15:47Z","timestamp":1685031347000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0000457"}},"subtitle":[],"editor":[{"given":"John Pius","family":"Dalton","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2009,6,9]]},"references-count":33,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2009,6,9]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0000457","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,6,9]]}}}