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Eldoret, Kenya: Moi University. 1\u2013282 p."},{"key":"ref45","article-title":"Environmental, Cultural and Social Changes and their Influence on Parasite Infections","author":"TN Petney","year":"2001","journal-title":"International Journal for Parasitology 31"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev.en.37.010192.000245","article-title":"The Analysis of Parasite Transmission by Blood-Sucking Insects","volume":"37","author":"C Dye","year":"1992","journal-title":"Annual Review of Entomology"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"e27","DOI":"10.1186\/1476-072X-4-27","article-title":"Towards understanding the presence\/absence of Human African Trypanosomosis in a focus of C\u00f4te d&apos;Ivoire:a spatial analysis of the pathogenic system","volume":"4","author":"F Courtin","year":"2005","journal-title":"International Journal of Health Geographics"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1080\/00034983.1986.11812048","article-title":"Trypanosoma Infection Rates in Glossina fuscipes fuscipes Newstead in Busoga Sleeping Sickness focus in Uganda","volume":"80","author":"J Okoth","year":"1986","journal-title":"Annals of Tropical Medicine and Parasitology"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1289\/ehp.6877","article-title":"Members of the Working Group on Land Use Change Disease Emergence. Unhealthy Landscapes: Policy Recommendations on Land Use Change and Infectious Disease Emergence","volume":"112","author":"JA Patz","year":"2004","journal-title":"Environmental Health Perspectives"},{"key":"ref50","unstructured":"Odiit M (2003) Epidemiology of Trypanosoma brucei rhodesiense Sleeping Sickness in Eastern Uganda [PhD Thesis]. United Kingdom: The University of Edinburgh."},{"key":"ref51","unstructured":"GoU (2006) Busia District Development Plan 2006\u20132009. Kampala, Uganda: The Republic of Uganda."},{"key":"ref52","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0001-706X(93)90072-J","article-title":"Isoenzyme Comparison of Trypanozoon Isolates from Two Sleeping Sickness Areas of South-eastern Uganda","volume":"55","author":"JK Enyaru","year":"1993","journal-title":"Acta Tropica"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1111\/j.1365-3156.2009.02271.x","article-title":"Trypanosoma Brucei Gambiense in Domestic Livestock of Kogo and Mbini foci (Equatorial Guinea)","volume":"14","author":"C Cordon-Obras","year":"2009","journal-title":"Tropical Medicine and International Health"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"e941","DOI":"10.1371\/journal.pntd.0000941","article-title":"Factors Associated with Acquisition of Human Infective and Animal Infective Trypanosome Infections in Domestic Livestock in Western Kenya","volume":"5","author":"B von Wissmann","year":"2011","journal-title":"PLoS Neglected Tropical Diseases"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1016\/S0140-6736(01)07096-9","article-title":"Identification of Human-Infective Trypanosomes in Animal Reservoir of Sleeping Sickness in Uganda by Means of Serum-Resistance-Associated (SRA) Gene","volume":"358","author":"SC Welburn","year":"2001","journal-title":"Lancet"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/0035-9203(84)90141-X","article-title":"Tsetse feeding habits in an area of endemic sleeping sickness in southern","volume":"78","author":"WF Snow","year":"1984","journal-title":"Transactions of the Royal Society of Tropical Medicine Hygiene"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/0001-706X(93)90089-T","article-title":"Current Situation of African Trypanosomiasis","volume":"54","author":"FA Kuzoe","year":"1993","journal-title":"Acta Tropica"}],"container-title":["PLoS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0002186","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T08:05:47Z","timestamp":1688198747000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0002186"}},"subtitle":[],"editor":[{"given":"Joseph Mathu","family":"Ndung'u","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,4,25]]},"references-count":57,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2013,4,25]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0002186","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,25]]}}}