{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T20:40:41Z","timestamp":1790887241037,"version":"4.1.0"},"reference-count":75,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2013,10,24]],"date-time":"2013-10-24T00:00:00Z","timestamp":1382572800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0002512","type":"journal-article","created":{"date-parts":[[2013,10,25]],"date-time":"2013-10-25T03:12:53Z","timestamp":1382670773000},"page":"e2512","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":35,"title":["In Pulmonary Paracoccidioidomycosis IL-10 Deficiency Leads to Increased Immunity and Regressive Infection without Enhancing Tissue Pathology"],"prefix":"10.1371","volume":"7","author":[{"given":"T\u00e2nia A.","family":"Costa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia B.","family":"Bazan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Feriotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliseu F.","family":"Ara\u00fajo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00canio J.","family":"Bassi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fl\u00e1vio V.","family":"Loures","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera L. G.","family":"Calich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2013,10,24]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/nri2939","article-title":"Immunity to fungal infections","volume":"11","author":"L Romani","year":"2011","journal-title":"Nat Rev Immunol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/nri1255","article-title":"Immunity to fungal infections","volume":"4","author":"L Romani","year":"2004","journal-title":"Nat Rev Immunol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev-immunol-030409-101229","article-title":"Innate antifungal immunity: the key role of phagocytes","volume":"29","author":"GD Brown","year":"2011","journal-title":"Annu Rev Immunol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.4049\/jimmunol.0801599","article-title":"TLR2 is a negative regulator of Th17 cells and tissue pathology in a pulmonary model of fungal infection","volume":"183","author":"FV Loures","year":"2009","journal-title":"J Immunol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0051071","article-title":"Anti-CD25 treatment depletes Treg cells and decreases disease severity in susceptible and resistant mice infected with <italic>Paracoccidioides brasiliensis<\/italic>","volume":"7","author":"M Felonato","year":"2012","journal-title":"PLoS One"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1128\/CMR.6.2.89","article-title":"Paracoccidioidomycosis: an update","volume":"6","author":"E Brummer","year":"1993","journal-title":"Clin Microbiol Rev"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1590\/S0100-879X1998000500003","article-title":"Cytokines produced by susceptible and resistant mice in the course of Paracoccidioides brasiliensis infection","volume":"31","author":"VL Calich","year":"1998","journal-title":"Braz J Med Biol Res"},{"key":"ref8","first-page":"585","article-title":"Susceptibility and resistance of inbred mice to <italic>Paracoccidioides brasiliensis<\/italic>","volume":"66","author":"VLG Calich","year":"1985","journal-title":"Brit J Exp Path"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1128\/IAI.66.2.800-806.1998","article-title":"Protective role of interferon-gamma in experimental pulmonary paracoccidioidomycosis","volume":"66","author":"LE Cano","year":"1998","journal-title":"Infect Immun"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S1473-3099(06)70577-1","article-title":"The two faces of interleukin 10 in human infectious diseases","volume":"6","author":"JL Mege","year":"2006","journal-title":"Lancet Infect Dis"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/nri2097","article-title":"T(H)1 cells control themselves by producing interleukin-10","volume":"7","author":"A O'Garra","year":"2007","journal-title":"Nat Rev Immunol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1600-065X.2008.00711.x","article-title":"Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulation","volume":"226","author":"CL Maynard","year":"2008","journal-title":"Immunol Rev"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"2964","DOI":"10.1128\/IAI.00047-11","article-title":"Interleukin-10 and immunity against prokaryotic and eukaryotic intracellular pathogens","volume":"79","author":"JC Cyktor","year":"2011","journal-title":"Infect Immun"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s12026-009-8150-5","article-title":"Cell type-specific regulation of IL-10 expression in inflammation and disease","volume":"47","author":"CM Hedrich","year":"2010","journal-title":"Immunol Res"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.cytogfr.2010.09.002","article-title":"Biology of interleukin-10","volume":"21","author":"R Sabat","year":"2010","journal-title":"Cytokine Growth Factor Rev"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1146\/annurev-immunol-031210-101312","article-title":"Regulation and functions of the IL-10 family of cytokines in inflammation and disease","volume":"29","author":"W Ouyang","year":"2011","journal-title":"Annu Rev Immunol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1038\/ni0909-929","article-title":"From IL-10 to IL-12: how pathogens and their products stimulate APCs to induce T(H)1 development","volume":"10","author":"A O'Garra","year":"2009","journal-title":"Nat Immunol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"5771","DOI":"10.4049\/jimmunol.180.9.5771","article-title":"IL-10: the master regulator of immunity to infection","volume":"180","author":"KN Couper","year":"2008","journal-title":"J Immunol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"3444","DOI":"10.4049\/jimmunol.146.10.3444","article-title":"IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells","volume":"146","author":"DF Fiorentino","year":"1991","journal-title":"J Immunol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1084\/jem.178.3.1041","article-title":"Interleukin-10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor\/IL-12 synthesis in accessory cells","volume":"178","author":"A D'Andrea","year":"1993","journal-title":"J Exp Med"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1084\/jem.20062175","article-title":"Conventional T-bet(+)Foxp3(\u2212) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection","volume":"204","author":"D Jankovic","year":"2007","journal-title":"J Exp Med"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1038\/nature10957","article-title":"Pathogen-induced human TH17 cells produce IFN-\u03b3 or IL-10 and are regulated by IL-1\u03b2","volume":"484","author":"CE Zielinski","year":"2012","journal-title":"Nature"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.ijid.2009.06.028","article-title":"Genetic variability of innate immunity impacts human susceptibility to fungal diseases","volume":"14","author":"A Carvalho","year":"2010","journal-title":"Int J Infect Dis"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1086\/432119","article-title":"<italic>Paracoccidioides brasiliensis<\/italic> disseminated disease in a patient with inherited deficiency in the beta1 subunit of the interleukin (IL)-12\/IL-23 receptor","volume":"41","author":"D Moraes-Vasconcelos","year":"2005","journal-title":"Clin Infect Dis"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s11046-007-9065-0","article-title":"An overview of the immunopathology of human paracoccidioidomycosis","volume":"165","author":"G Benard","year":"2008","journal-title":"Mycopathologia"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1080\/13693780801971450","article-title":"Cell mediated immunity to fungi: a reassessment","volume":"46","author":"L Romani","year":"2008","journal-title":"Med Mycol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1086\/429964","article-title":"Influence of interleukin-10 on <italic>Aspergillus fumigatus<\/italic> infection in patients with cystic fibrosis","volume":"191","author":"J Brouard","year":"2005","journal-title":"J Infect Dis"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1006\/cyto.2002.0884","article-title":"IL-12 and neutralization of endogenous IL-10 revert the <italic>in vitro<\/italic> antigen-specific cellular immunosuppression of paracoccidioidomycosis patients","volume":"18","author":"CC Romano","year":"2002","journal-title":"Cytokine"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.clim.2004.09.005","article-title":"The role of interleukin-10 in the differential expression of interleukin-12p70 and its beta2 receptor on patients with active or treated paracoccidioidomycosis and healthy infected subjects","volume":"114","author":"CC Romano","year":"2005","journal-title":"Clin Immunol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1089\/107999000312766","article-title":"Resistance to <italic>Paracoccidioides brasiliensis<\/italic> infection is linked to a preferential Th1 immune response, whereas susceptibility is associated with absence of IFN-gamma production","volume":"20","author":"SS Kashino","year":"2000","journal-title":"J Interferon Cytokine Res"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1086\/314479","article-title":"Suppressive effects of interleukin-10 on human mononuclear phagocyte function against <italic>Candida albicans<\/italic> and <italic>Staphylococcus aureus<\/italic>","volume":"178","author":"E Roilides","year":"1998","journal-title":"J Infect Dis"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.cellimm.2010.03.016","article-title":"Interleukin-10 but not Transforming Growth Factor beta inhibits murine activated macrophages <italic>Paracoccidioides brasiliensis<\/italic> killing: effect on H<sub>2<\/sub>O<sub>2<\/sub> and NO production","volume":"263","author":"AP Moreira","year":"2010","journal-title":"Cell Immunol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"3514","DOI":"10.4049\/jimmunol.152.7.3514","article-title":"Neutralization of IL-10 up-regulates nitric oxide production and protects susceptible mice from challenge with <italic>Candida albicans<\/italic>","volume":"152","author":"L Romani","year":"1994","journal-title":"J Immunol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"3601","DOI":"10.1128\/IAI.67.7.3601-3609.1999","article-title":"Differential regulation of immune responses by highly and weakly virulent <italic>Cryptococcus neoformans<\/italic> isolates","volume":"67","author":"R Blackstock","year":"1999","journal-title":"Infect Immun"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/S1286-4579(99)00245-2","article-title":"Antifungal type 1 responses are upregulated in IL-10-deficient mice","volume":"1","author":"G Del Sero","year":"1999","journal-title":"Microbes Infect"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1046\/j.1365-2249.2000.01382.x","article-title":"Role of IL-10 in invasive aspergillosis: increased resistance of IL-10 gene knockout mice to lethal systemic aspergillosis","volume":"122","author":"KV Clemons","year":"2000","journal-title":"Clin Exp Immunol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"5353","DOI":"10.4049\/jimmunol.171.10.5353","article-title":"Protective and memory immunity to <italic>Histoplasma capsulatum<\/italic> in the absence of IL-10","volume":"171","author":"GS Deepe Jr","year":"2003","journal-title":"J Immunol"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/BF02282801","article-title":"Alterations in the pathogenicity of one <italic>Paracoccidioides brasiliensis<\/italic> isolate do not correlative with its in vitro growth","volume":"111","author":"SS Kashino","year":"1990","journal-title":"Mycopathologia"},{"key":"ref39","first-page":"177","article-title":"Ant\u00edgeno polissacar\u00eddico do <italic>Paracoccidioides brasiliensis<\/italic>. Estudo do tempo de cultivo do <italic>P. brasiliensis<\/italic> necess\u00e1rio ao preparo do ant\u00edgeno","volume":"11","author":"C Fava Netto","year":"1969","journal-title":"Rev Inst Med Trop"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1128\/IAI.63.5.1777-1783.1995","article-title":"Pulmonary paracoccidioidomycosis in resistant and susceptible mice: relationship among progression of infection, bronchoalveolar cell activation, cellular immune response, and specific isotype patterns","volume":"63","author":"LE Cano","year":"1995","journal-title":"Infect Immun"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1080\/02681219280000331","article-title":"The source of the growth-promoting factor(s) affects the plating efficiency of <italic>Paracoccidioides brasiliensis<\/italic>","volume":"30","author":"LM Singer-Vermes","year":"1992","journal-title":"J Med Vet Mycol"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.4049\/jimmunol.141.7.2407","article-title":"Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages","volume":"141","author":"AH Ding","year":"1988","journal-title":"J Immun"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/BF01103767","article-title":"Delayed-type hypersensitivity response in an isogenic murine model of paracoccidioidomycosis","volume":"126","author":"RA Fazioli","year":"1994","journal-title":"Mycopathologia"},{"key":"ref44","first-page":"197","article-title":"Estudos quantitativos sobre fixa\u00e7\u00e3o do complemento na blastomicose sul-americana com ant\u00edgeno polissacar\u00eddico","volume":"18","author":"C Fava Netto","year":"1955","journal-title":"Arq Cir Clin Exp"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"847","DOI":"10.2353\/ajpath.2006.050522","article-title":"Distinct compartmentalization of CD4+T-cell effector function versus proliferative capacity during pulmonary cryptococcosis","volume":"168","author":"DM Lindell","year":"2006","journal-title":"Am J Pathol"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1080\/02681219180000061","article-title":"The use of cell-free antigens of <italic>Paracoccidioides brasiliensis<\/italic> in serological tests","volume":"29","author":"ZP Camargo","year":"1991","journal-title":"J Med Vet Mycol"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"3478","DOI":"10.1128\/JCM.38.9.3478-3480.2000","article-title":"PCR for diagnosis of paracoccidioidomycosis","volume":"38","author":"GM Gomes","year":"2000","journal-title":"J Clin Microbiol"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1006\/cyto.2000.0824","article-title":"Imbalance of IL-12, IFN-gamma and IL-10 secretion in the immunsupression associated with human paracoccidioidomycosis","volume":"13","author":"G Benard","year":"2001","journal-title":"Cytokine"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.cyto.2006.08.005","article-title":"Flow-cytometric analysis of cytokine production in human paracoccidioidomycosis","volume":"35","author":"RL Mamoni","year":"2006","journal-title":"Cytokine"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1126\/science.1069659","article-title":"Resolution of lung inflammation by CD44","volume":"296","author":"P Teder","year":"2002","journal-title":"Science"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.4049\/jimmunol.148.6.1792","article-title":"IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages","volume":"148","author":"RT Gazzinelli","year":"1992","journal-title":"J Immunol"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1002\/eji.1830260214","article-title":"Administration of interleukin-10 abolishes innate resistance to Listeria monocytogenes","volume":"26","author":"JP Kelly","year":"1996","journal-title":"Eur J Immunol"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.immuni.2006.02.014","article-title":"IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB\/AP-1proteins","volume":"24","author":"X Hu","year":"2006","journal-title":"Immunity"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1189\/jlb.0603252","article-title":"Interferon-gamma: an overview of signals, mechanisms and functions","volume":"75","author":"K Schroder","year":"2004","journal-title":"J Leukoc Biol"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"e54845, 1","DOI":"10.1371\/journal.pone.0054845","article-title":"Mannosyl-recognizing receptors induce an M1-like phenotype in macrophages of susceptible mice but an M2-like phenotype in mice resistant to a fungal infection","volume":"8","author":"C Feriotti","year":"2013","journal-title":"PLoS One"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"4790","DOI":"10.4049\/jimmunol.155.10.4790","article-title":"The role of monocyte chemotactic protein-1 (MCP-1) in the recruitment of monocytes and CD4+ T cells during a pulmonary <italic>Cryptococcus neoformans<\/italic> infection","volume":"155","author":"GB Huffnagle","year":"1995","journal-title":"J Immunol"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"6525","DOI":"10.4049\/jimmunol.167.11.6525","article-title":"Monocyte chemoattractant protein-1-dependent increase of V\u03b114 NKT cells lungs and their roles in Th1 response and host defense in Cryptococcal infection","volume":"167","author":"K Kawakami","year":"2001","journal-title":"J Immunol"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1046\/j.1365-2249.1998.00636.x","article-title":"Mice incapable of making IL-4 or IL-10 display normal resistance to infection with <italic>Mycobacterium tuberculosis<\/italic>","volume":"113","author":"RJ North","year":"1998","journal-title":"Clin Exp Immunol"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.4049\/jimmunol.162.2.1010","article-title":"IL-10 gene knockout mice show enhanced Th1-like protective immunity and absent granuloma formation following <italic>Chlamydia trachomatis<\/italic> lung infection","volume":"162","author":"X Yang","year":"1999","journal-title":"J Immunol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"5152","DOI":"10.4049\/jimmunol.170.10.5152","article-title":"The relative contribution of IL-4 receptor signaling and IL-10 to susceptibility to <italic>Leishmania major<\/italic>","volume":"170","author":"N Noben-Trauth","year":"2003","journal-title":"J Immunol"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"2848","DOI":"10.1002\/1521-4141(2001010)31:10<2848::AID-IMMU2848>3.0.CO;2-T","article-title":"IL-10 mediates susceptibility to <italic>Leishmania donovani<\/italic> infection","volume":"31","author":"ML Murphy","year":"2001","journal-title":"Eur J Immunol"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"4435","DOI":"10.1128\/IAI.67.9.4435-4442.1999","article-title":"A defect in interleukin-10 leads to enhanced malarial disease in <italic>Plasmodium chabaudi chabaudi<\/italic> infection in mice","volume":"67","author":"C Li","year":"1999","journal-title":"Infect Immun"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"3311","DOI":"10.4049\/jimmunol.158.7.3311","article-title":"IL-10 is required to prevent immune hyperactivity during infection with <italic>Trypanosoma cruzi<\/italic>","volume":"158","author":"CA Hunter","year":"1997","journal-title":"J Immunol"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"798","DOI":"10.4049\/jimmunol.157.2.798","article-title":"In the absence of endogenous IL-10, mice acutely infected with <italic>Toxoplasma gondii<\/italic> succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha","volume":"157","author":"RT Gazzinelli","year":"1996","journal-title":"J Immunol"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S1473-3099(06)70577-1","article-title":"The two faces of interleukin 10 in human infectious diseases","volume":"6","author":"JL Mege","year":"2006","journal-title":"Lancet Infect Dis"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"4647","DOI":"10.1128\/IAI.59.12.4647-4654.1991","article-title":"Th1 and Th2 cytokine secretion patterns in murine candidiasis: association of Th1 responses with acquired resistance","volume":"59","author":"L Romani","year":"1991","journal-title":"Infect Immun"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1128\/IAI.66.2.786-793.1998","article-title":"Mapping of the T-cell epitope in the major 43-kilodalton glycoprotein of <italic>Paracoccidioides brasiliensis<\/italic> which induces a Th-1 response protective against fungal infection in BALB\/c mice","volume":"66","author":"CP Taborda","year":"1998","journal-title":"Infect Immun"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/S1369-5274(02)00337-5","article-title":"Induced humoral immunity and vaccination against major human fungal pathogens","volume":"5","author":"A Casadevall","year":"2002","journal-title":"Curr Opin Microbiol"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1128\/IAI.67.2.670-674.1999","article-title":"Early resistance of interleukin-10 knockout mice to acute systemic candidiasis","volume":"67","author":"A Vazquez-Torres","year":"1999","journal-title":"Infect Immun"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"3087","DOI":"10.1128\/IAI.67.6.3087-3095.1999","article-title":"Increased antimycobacterial immunity in interleukin-10-deficient mice","volume":"67","author":"PJ Murray","year":"1999","journal-title":"Infect Immun"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.4049\/jimmunol.158.5.2259","article-title":"Both innate and acquired immunity to Listeria monocytogenes infection are increased in IL-10-deficient mice","volume":"158","author":"WJ Dai","year":"1997","journal-title":"J Immunol"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1128\/IAI.01443-08","article-title":"Monoclonal antibodies to heat shock protein 60 alter the pathogenesis of <italic>Histoplasma capsulatum<\/italic>","volume":"77","author":"AJ Guimar\u00e3es","year":"2009","journal-title":"Infect Immun"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1172\/JCI19361","article-title":"Antibodies to a cell surface histone-like protein protect against <italic>Histoplasma capsulatum<\/italic>","volume":"12","author":"JD Nosanchuk","year":"2003","journal-title":"J Clin Invest"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"3712","DOI":"10.4049\/jimmunol.172.6.3712","article-title":"Toll-like receptor 2 suppresses immunity against <italic>Candida albicans<\/italic> through induction of IL-10 and regulatory T cells","volume":"172","author":"MG Netea","year":"2004","journal-title":"J Immunol"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"6298","DOI":"10.4049\/jimmunol.169.11.6298","article-title":"B7\/CD28-dependent CD4+CD25+ regulatory T cells are essential components of the memory-protective immunity to <italic>Candida albicans<\/italic>","volume":"169","author":"C Montagnoli","year":"2002","journal-title":"J Immunol"}],"container-title":["PLoS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0002512","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T22:25:00Z","timestamp":1716071100000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0002512"}},"subtitle":[],"editor":[{"given":"Joseph M.","family":"Vinetz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,10,24]]},"references-count":75,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2013,10,24]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0002512","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,24]]}}}