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(1995) Report on the consultative meeting on Leishmania\/HIV co-infection. report no. WHO\/LEISH\/95.35, pp. 1\u201314. Geneva: World Health Organization."},{"key":"ref2","first-page":"62","article-title":"Epidemiology of visceral leishmaniasis in india","volume":"12","author":"D Bora","year":"1999","journal-title":"Natl Med J India"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"e000926","DOI":"10.1136\/bmjopen-2012-000926","article-title":"Estimate of HIV prevalence and number of people living with HIV in india 2008\u20132009","volume":"2","author":"A Pandey","year":"2012","journal-title":"BMJ Open"},{"key":"ref4","unstructured":"Government of India, Ministry of Health and Family Welfare. (2010) United Nations general assembly special session on HIV\/AIDS country report: India."},{"key":"ref5","doi-asserted-by":"crossref","first-page":"80","DOI":"10.3389\/fimmu.2012.00080","article-title":"T helper1\/t helper2 cells and resistance\/susceptibility to leishmania infection: Is this paradigm still relevant?","volume":"3","author":"J Alexander","year":"2012","journal-title":"Front Immunol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"e1002635","DOI":"10.1371\/journal.ppat.1002635","article-title":"Leishmania induces survival, proliferation and elevated cellular dNTP levels in human monocytes promoting acceleration of HIV co-infection","volume":"8","author":"DJ Mock","year":"2012","journal-title":"PLoS Pathog"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/QCO.0b013e32835c2198","article-title":"Clinical aspects of visceral leishmaniasis in HIV infection","volume":"26","author":"JN Jarvis","year":"2013","journal-title":"Curr Opin Infect Dis"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1128\/CMR.00061-07","article-title":"The relationship between leishmaniasis and AIDS: The second 10 years","volume":"21","author":"J Alvar","year":"2008","journal-title":"Clin Microbiol Rev"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/00126334-200301010-00017","article-title":"Visceral leishmaniasis and HIV coinfection in Bihar, India","volume":"32","author":"PK Sinha","year":"2003","journal-title":"J Acquir Immune Defic Syndr"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1097\/00126334-200304150-00017","article-title":"Kala-azar (visceral leishmaniasis) and HIV coinfection in Bihar, India: Is this combination increasing?","volume":"32","author":"CP Thakur","year":"2003","journal-title":"J Acquir Immune Defic Syndr"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1097\/01.aids.0000226971.42622.4e","article-title":"Leishmania-HIV co-infection: An emerging problem in India","volume":"20","author":"NS Redhu","year":"2006","journal-title":"AIDS"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1099\/jmm.0.46574-0","article-title":"Visceral leishmaniasis\/human immunodeficiency virus co-infection in India: The focus of two epidemics","volume":"55","author":"P Mathur","year":"2006","journal-title":"J Med Microbiol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/S0035-9203(00)90238-4","article-title":"Miltefosine in a case of visceral leishmaniasis with HIV co-infection; and rising incidence of this disease in india","volume":"94","author":"CP Thakur","year":"2000","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref14","article-title":"HIV and visceral leishmaniasis co-infection in Bihar, India: An under-recognised and under-diagnosed threat against elimination","author":"S Burza","year":"2014","journal-title":"Clin Infect Dis"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"e2195","DOI":"10.1371\/journal.pntd.0002195","article-title":"Efficacy of anti-leishmania therapy in visceral leishmaniasis among HIV infected patients: A systematic review with indirect comparison","volume":"7","author":"GF Cota","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1517\/14728214.2012.748036","article-title":"Liposomal amphotericin B as a treatment for human leishmaniasis","volume":"17","author":"M Balasegaram","year":"2012","journal-title":"Expert Opin Emerg Drugs"},{"key":"ref17","unstructured":"WHO control of the leishmaniasis (2010) Report of a meeting of the WHO expert committee on the control of leishmaniasis, 22\u201326 March 2010. Geneva: WHO."},{"key":"ref18","doi-asserted-by":"crossref","first-page":"e2603","DOI":"10.1371\/journal.pntd.0002603","article-title":"Five-year field results and long-term effectiveness of 20 mg\/kg liposomal amphotericin B (ambisome) for visceral leishmaniasis in Bihar, India","volume":"8","author":"S Burza","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"ref19","first-page":"951","article-title":"Laboratory diagnosis of visceral leishmaniasis","volume":"9","author":"S Sundar","year":"2002","journal-title":"Clin Diagn Lab Immunol"},{"key":"ref20","unstructured":"World Health Organization (2011) Field safety notice no. 1, 2011. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/Http:\/\/www.who.int\/diagnostics_laboratory\/procurement\/111201_productalert_for_product0027_mx012.pdf\" xlink:type=\"simple\">Http:\/\/www.who.int\/diagnostics_laboratory\/procurement\/111201_productalert_for_product0027_mx012.pdf<\/ext-link>. Accessed 25 January 2014."},{"key":"ref21","unstructured":"World Health Organization (2010) Indicators for monitoring and evaluation of the kala-azar elimination programme. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.who.int\/tdr\/publications\/documents\/kala_azar_indicators.pdf\" xlink:type=\"simple\">http:\/\/www.who.int\/tdr\/publications\/documents\/kala_azar_indicators.pdf<\/ext-link>. Accessed 1 June 2014."},{"key":"ref22","doi-asserted-by":"crossref","first-page":"357","DOI":"10.4269\/ajtmh.2010.10-0156","article-title":"Effectiveness and safety of liposomal amphotericin B for visceral leishmaniasis under routine program conditions in Bihar, India","volume":"83","author":"PK Sinha","year":"2010","journal-title":"Am J Trop Med Hyg"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"e91","DOI":"10.1093\/cid\/cir521","article-title":"Liposomal amphotericin B for visceral leishmaniasis in human immunodeficiency virus-coinfected patients: 2-year treatment outcomes in Bihar, India","volume":"53","author":"PK Sinha","year":"2011","journal-title":"Clin Infect Dis"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1177\/1536867X0400400301","article-title":"Multiple imputation of missing values","volume":"4","author":"P Royston","year":"2004","journal-title":"Stata Journal"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1093\/aje\/kwp107","article-title":"Competing risk regression models for epidemiologic data","volume":"170","author":"B Lau","year":"2009","journal-title":"Am J Epidemiol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1002\/(SICI)1097-0258(19970430)16:8<901::AID-SIM543>3.0.CO;2-M","article-title":"Non-parametric inference for cumulative incidence functions in competing risks studies","volume":"16","author":"DY Lin","year":"1997","journal-title":"Stat Med"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"e1153","DOI":"10.1371\/journal.pntd.0001153","article-title":"Predictors of visceral leishmaniasis relapse in HIV-infected patients: A systematic review","volume":"5","author":"GF Cota","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1086\/587899","article-title":"Concordant HIV infection and visceral leishmaniasis in Ethiopia: The influence of antiretroviral treatment and other factors on outcome","volume":"46","author":"R ter Horst","year":"2008","journal-title":"Clin Infect Dis"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"e152","DOI":"10.1093\/cid\/cir674","article-title":"Limited effectiveness of high-dose liposomal amphotericin B (AmBisome) for treatment of visceral leishmaniasis in an ethiopian population with high HIV prevalence","volume":"53","author":"K Ritmeijer","year":"2011","journal-title":"Clin Infect Dis"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"e2536","DOI":"10.1371\/journal.pntd.0002536","article-title":"Risk factors for visceral leishmaniasis relapse in immunocompetent patients following treatment with 20 mg\/kg liposomal amphotericin B (ambisome) in Bihar, India","volume":"8","author":"S Burza","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1093\/cid\/cit508","article-title":"One-year follow-up of immunocompetent male patients treated with miltefosine for primary visceral leishmaniasis in Bihar, India","volume":"57","author":"S Burza","year":"2013","journal-title":"Clin Infect Dis"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1093\/cid\/cit102","article-title":"Increasing failure of miltefosine in the treatment of kala-azar in Nepal and the potential role of parasite drug resistance, reinfection, or noncompliance","volume":"56","author":"S Rijal","year":"2013","journal-title":"Clin Infect Dis"},{"key":"ref33","unstructured":"National AIDS Control Organization (2007) Antiretroviral therapy guidelines for HIV-infected adults and adolescents, including post-exposure prophylaxis, May 2007, 125 pp."},{"key":"ref34","doi-asserted-by":"crossref","first-page":"e66860","DOI":"10.1371\/journal.pone.0066860","article-title":"Adherence to antiretroviral therapy and its effect on survival of HIV-infected individuals in Jharkhand, India","volume":"8","author":"S Rai","year":"2013","journal-title":"PLoS One"},{"key":"ref35","unstructured":"National AIDS Control Organization And Central TB Division (2010) Ministry of health &amp; family welfare government of India, New Delhi. TB\/HIV module for ART centre staff. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.tbcindia.nic.in\/pdfs\/TB-HIV%20Module%20for%20ART%20Centre%20Staff.pdf\" xlink:type=\"simple\">http:\/\/www.tbcindia.nic.in\/pdfs\/TB-HIV%20Module%20for%20ART%20Centre%20Staff.pdf<\/ext-link>. Accessed: 1 May 2014."},{"key":"ref36","unstructured":"National AIDS Control organisation Ministry of Health and Family Welfare Government of India (2012) Operational guidelines for ART services 2012. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/Http:\/\/www.naco.gov.in\/upload\/Publication\/Treatment%20Care%20and%20support\/Operational%20guidelines%20for%20ART%20services.pdf\" xlink:type=\"simple\">Http:\/\/www.naco.gov.in\/upload\/Publication\/Treatment%20Care%20and%20support\/Operational%20guidelines%20for%20ART%20services.pdf<\/ext-link> Accessed 26 January 2014."},{"key":"ref37","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S1473-3099(10)70011-6","article-title":"Combination therapy for visceral leishmaniasis","volume":"10","author":"J van Griensven","year":"2010","journal-title":"Lancet Infect Dis"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1128\/AAC.00030-11","article-title":"Mechanism of amphotericin B resistance in clinical isolates of leishmania donovani","volume":"56","author":"B Purkait","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1128\/AAC.42.8.2141","article-title":"Leishmania infantum: Lack of parasite resistance to amphotericin B in a clinically resistant visceral leishmaniasis","volume":"42","author":"R Durand","year":"1998","journal-title":"Antimicrob Agents Chemother"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"e16","DOI":"10.1086\/595710","article-title":"Parasite susceptibility to amphotericin B in failures of treatment for visceral leishmaniasis in patients coinfected with HIV type 1 and leishmania infantum","volume":"48","author":"L Lachaud","year":"2009","journal-title":"Clin Infect Dis"},{"key":"ref41","article-title":"Multiple relapses of viceral leishmaniasis in a patient with HIV in India: A treatment challenge. International journal of infectious diseases","author":"S Patole","year":"2014","journal-title":"Int J Infect Dis"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"e1284","DOI":"10.1371\/journal.pntd.0001284","article-title":"Incidence of symptomatic and asymptomatic leishmania donovani infections in high-endemic foci in India and Nepal: A prospective study","volume":"5","author":"B Ostyn","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"key":"ref43","unstructured":"National vector borne disease control programme (2008) Directorate general of health services, ministry of health and family welfare. project implementation plan: National vector borne disease control support project under world bank on malaria control &amp; kala-azar elimination (2008\u20132013). Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/Http:\/\/nvbdcp.gov.in\/Doc\/PIP.pdf\" xlink:type=\"simple\">Http:\/\/nvbdcp.gov.in\/Doc\/PIP.pdf<\/ext-link>. Accessed 20 January 2014."}],"container-title":["PLoS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0003053","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T03:05:25Z","timestamp":1588993525000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0003053"}},"subtitle":[],"editor":[{"given":"Abhay R.","family":"Satoskar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,8,7]]},"references-count":43,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2014,8,7]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0003053","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8,7]]}}}