{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:58:37Z","timestamp":1791233917710,"version":"4.1.0"},"reference-count":27,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2014,7,31]],"date-time":"2014-07-31T00:00:00Z","timestamp":1406764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0003058","type":"journal-article","created":{"date-parts":[[2014,7,31]],"date-time":"2014-07-31T21:04:34Z","timestamp":1406840674000},"page":"e3058","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":63,"title":["Treatment of Tungiasis with Dimeticone: A Proof-of-Principle Study in Rural Kenya"],"prefix":"10.1371","volume":"8","author":[{"given":"Marlene","family":"Thielecke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Nordin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Ngomi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hermann","family":"Feldmeier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,7,31]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"152","DOI":"10.2471\/BLT.07.047308","article-title":"Epidermal parasitic skin diseases: a neglected category of poverty-associated plagues","volume":"87","author":"H Feldmeier","year":"2009","journal-title":"Bull World Health Org"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/j.0269-283X.2004.00532.x","article-title":"The animal reservoir of <italic>Tunga penetrans<\/italic> in severely affected communities of north-east Brazil","volume":"18","author":"J Heukelbach","year":"2004","journal-title":"Med Vet Entomol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1046\/j.1365-3156.2001.00716.x","article-title":"Tungiasis: a neglected health problem of poor communities","volume":"6","author":"J Heukelbach","year":"2001","journal-title":"Trop Med Int Health"},{"key":"ref4","first-page":"63","article-title":"Tungiasis: a neglected disease causing severe morbidity in a shantytown in Fortaleza, State of Cear\u00e1","volume":"40","author":"L Ariza","year":"2007","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref5","first-page":"107","article-title":"Tungiasis among five communities in south-western Trinidad, West Indies","volume":"92","author":"DD Chadee","year":"1998","journal-title":"Ann Trop Med Parasitol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.trstmh.2005.06.033","article-title":"Identifying risk factor for tungiasis and heavy infestation in a resource-poor community in northeast Brazil","volume":"100","author":"M Muehlen","year":"2006","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref7","first-page":"551","article-title":"<italic>Tunga penetrans<\/italic> (Insecta, Siphonaptera, Tungidae) \u00e0 Madagascar: une nuisance n\u00e9glig\u00e9e","volume":"11","author":"J Ratovonjato","year":"2008","journal-title":"Revue Med Vet"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0001-706X(02)00133-X","article-title":"High prevalence of tungiasis in a poor neighbourhood in Fortaleza, Northeast Brazil","volume":"83","author":"T Wilcke","year":"2002","journal-title":"Acta Trop"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s10096-012-1725-4","article-title":"Tungiasis (sand flea disease): a parasitic disease with intriguing challenges for public health","volume":"32","author":"H Feldmeier","year":"2012","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"ref10","unstructured":"Ahadi Kenya Trust (2010) The Jigger Menace in Kenya Report Volume 2. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.jigger-ahadi.org\/anti_jigger_magazine_year_2_%20final.pdf\" xlink:type=\"simple\">http:\/\/www.jigger-ahadi.org\/anti_jigger_magazine_year_2_%20final.pdf<\/ext-link>. Accessed 25 March 2014."},{"key":"ref11","doi-asserted-by":"crossref","first-page":"949","DOI":"10.3201\/eid0908.030041","article-title":"Severe tungiasis in underprivileged communities: case series from Brazil","volume":"9","author":"H Feldmeier","year":"2003","journal-title":"Emerg Infect Dis"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1007\/s00436-003-0950-2","article-title":"Investigations on the biology, epidemiology, pathology and control of <italic>Tunga penetrans<\/italic> in Brazil: III. Determination of cytokines in the peripheral blood of infected humans","volume":"91","author":"H Feldmeier","year":"2003","journal-title":"Parasitol Res"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1046\/j.1365-3156.2002.00904.x","article-title":"Bacterial superinfection in human tungiasis","volume":"7","author":"H Feldmeier","year":"2002","journal-title":"Trop Med Int Health"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s00436-002-0817-y","article-title":"Investigations on the biology, epidemiology, pathology and control of <italic>Tunga penetrans<\/italic> in Brazil: I. Natural history of tungiasis in man","volume":"90","author":"M Eisele","year":"2003","journal-title":"Parasitol Res"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.tmaid.2013.10.001","article-title":"Tungiasis - A Janus-faced parasitic skin disease","volume":"11","author":"H Feldmeier","year":"2013","journal-title":"Travel Med Infect Dis"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s00436-004-1197-2","article-title":"Investigations on the biology, epidemiology, pathology and control of <italic>Tunga penetrans<\/italic> in Brazil. IV. Clinical and histopathology","volume":"94","author":"H Feldmeier","year":"2004","journal-title":"Parasitol Res"},{"key":"ref17","unstructured":"Joyeux CH, Sic\u00e9 A (1937) Pr\u00e9cis de M\u00e9decine Coloniale. Masson et Cte, Paris. 441 p."},{"key":"ref18","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/j.trstmh.2005.11.006","article-title":"Tungiasis in rural Haiti: a community-based response","volume":"100","author":"JK Joseph","year":"2006","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref19","first-page":"20\/LB-2098A","article-title":"Health hazards associated with traditional treatment of tungiasis","volume":"89","author":"H Feldmeier","year":"2013","journal-title":"Am J Trop Med Hyg"},{"key":"ref20","first-page":"1","article-title":"Tungiasis in the past and present: A dire need for intervention","volume":"28","author":"J Heukelbach","year":"2007","journal-title":"Niger J Parasitol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1590\/S0074-02762004000800015","article-title":"Therapy of tungiasis: a double-binded randomized controlled trial with oral ivermectin","volume":"99","author":"J Heukelbach","year":"2004","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"ref22","first-page":"77","article-title":"Dimeticone-Based Pediculocides: A Physical Approach to Eradicate Head Lice","volume":"4","author":"J Heuckelbach","year":"2010","journal-title":"Open Dermatol J"},{"key":"ref23","first-page":"248","article-title":"Lethal effects of treatment with a special dimeticone formula on head lice and house crickets (Orthoptera, Ensifera: <italic>Acheta domestica<\/italic> and Anoplura, Phthiraptera: <italic>Pediculus humanus<\/italic>)","volume":"58","author":"I Richling","year":"2008","journal-title":"Drug Res"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1177\/1091581803022S204","article-title":"Final report on the safety assessment of stearoxy dimethicone, dimethicone, methicone, amino bispropyl dimethicone, aminopropyl dimethicone, amodimethicone, amodimethicone hydroxystearate, behenoxy dimethicone, C24\u201328 alkyl methicone, C30\u201345 alkyl methicone, C30\u201345 alkyl dimethicone, cetearyl methicone, cetyl dimethicone, dimethoxysilyl ethylenediaminopropyl dimethicone, hexyl methicone, hydroxypropyldimethicone, stearamidopropyl dimethicone, stearyl dimethicone, stearyl methicone, and vinyldimethicone","volume":"22","author":"B Nair","year":"2003","journal-title":"Int J Toxicol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"932","DOI":"10.4269\/ajtmh.13-0244","article-title":"Regression of severe tungiasis-associated morbidity after prevention of re-infestation: A case series from rural Madagascar","volume":"89","author":"M Thielecke","year":"2013","journal-title":"Am J Trop Med Hyg"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/1471-2334-8-115","article-title":"A highly efficacious pediculicide based on dimeticone: randomized observer blinded comparative trial","volume":"8","author":"J Heukelbach","year":"2008","journal-title":"BMC Infect Dis"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"e2462","DOI":"10.1371\/journal.pntd.0002426","article-title":"Prevention of tungiasis and tungiasis-associated morbidity using the plant-based repellent Zanzarin: A randomized, controlled field study in rural Madagascar","volume":"7","author":"M Thielecke","year":"2013","journal-title":"PloS Negl Trop Dis"}],"container-title":["PLoS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0003058","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,22]],"date-time":"2020-08-22T20:28:47Z","timestamp":1598128127000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0003058"}},"subtitle":[],"editor":[{"given":"Joseph M.","family":"Vinetz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,7,31]]},"references-count":27,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2014,7,31]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0003058","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,31]]}}}